iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115317

Ensembl Protein ID

ENSSSCP00000003147.2

UniProt Accession

F1RLF2; F1RLF2_PIG

Genbank Protein ID

ENSSSCP00000003147

Protein Name

WD repeat-containing protein 62

Genbank Nucleotide ID

CU694686

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000002923.2	ENSSSCT00000003228.2	ENSSSCP00000003147.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-28	95.8	153	190
UBD/Beta-Prp	9.80e-56	189.4	491	754

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkgh 93
           +k+ ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ +++  +tl  h
   Q: 491  MKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVRVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYSLEQTLDDH 579
           6777899*********************************************99887899**************99967788899**** PP
   S: 94   edsvlslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkl 171
           ++s+++++f  s+   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+
   Q: 580  SSSITAVKFTGSRdIQMISCGADKSIYF---RSAQQASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKC 665
           ***********775789*******9976...333333334445332122222333446777788****************988888888 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrs 253
            +  +g +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ ++ ++f+ +  +l+++s D  ++iW       ++ +
   Q: 666  YKGSQG-DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIITGMKFTYDCRHLITVSGDSCVFIWhlgpeitNCMK 753
           888888.999999999**************************************************************66555555444 PP
   S: 254  g 254
           +
   Q: 754  Q 754
           4 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MAALGTGGYV RNDAVEKLPT IMAGVPARRA QSSPPPAPPL CLRRRTRLTA APEDAVQNRV 60
SLEKVLGITA QNSSGLTCDP GTGHVAYLAG CVVVILNPKE NKQQHILNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCCGCGG CGGTTCGCTA TTCGAGTGGG TTGCGGCGGC GGCGGCGGCG GCGGCAGTTG 60
GGCGTGTAAC GGTCGCCCGG CCCTGGCGCG ACGATGGCGG CCTTGGGGAC CGGAGGCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	83.78	0.00e+00	2410.00
IUUC-Aca-004935	Anolis carolinensis	71.30	0.00e+00	1006.00
IUUC-Ath-007624	Arabidopsis thaliana	30.65	7.00e-93	335.00
IUUC-Acl-008257	Aspergillus clavatus	21.08	5.00e-23	103.00
IUUC-Afu-008757	Aspergillus fumigatus	21.46	2.00e-27	118.00
IUUC-Bta-013336	Bos taurus	83.08	0.00e+00	2358.00
IUUC-Cel-018592	Caenorhabditis elegans	28.53	2.00e-73	271.00
IUUC-Cja-019094	Callithrix jacchus	79.34	0.00e+00	2217.00
IUUC-Cfa-020529	Canis familiaris	83.45	0.00e+00	2395.00
IUUC-Cpo-021970	Cavia porcellus	86.26	0.00e+00	1629.00
IUUC-Csa-024161	Chlorocebus sabaeus	79.65	0.00e+00	2192.00
IUUC-Cho-024310	Choloepus hoffmanni	85.12	0.00e+00	1153.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.59	3.00e-23	103.00
IUUC-Dno-029933	Dasypus novemcinctus	77.51	0.00e+00	2125.00
IUUC-Dor-031147	Dipodomys ordii	76.91	0.00e+00	2066.00
IUUC-Dse-031501	Dothistroma septosporum	29.39	4.00e-22	100.00
IUUC-Eca-033675	Equus caballus	83.66	0.00e+00	2387.00
IUUC-Fca-035826	Felis catus	84.16	0.00e+00	2457.00
IUUC-Gma-043644	Glycine max	31.32	2.00e-101	363.00
IUUC-Ggo-045152	Gorilla gorilla	81.21	0.00e+00	2202.00
IUUC-Hsa-045891	Homo sapiens	81.34	0.00e+00	2217.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.81	0.00e+00	1528.00
IUUC-Lch-049669	Latimeria chalumnae	63.28	0.00e+00	1001.00
IUUC-Loc-052488	Lepisosteus oculatus	60.24	0.00e+00	1028.00
IUUC-Laf-053992	Loxodonta africana	79.53	0.00e+00	2255.00
IUUC-Mcc-054994	Macaca mulatta	80.69	0.00e+00	2197.00
IUUC-Meu-056815	Macropus eugenii	78.14	0.00e+00	1397.00
IUUC-Mtr-058383	Medicago truncatula	29.81	1.00e-49	190.00
IUUC-Mmr-060693	Microcebus murinus	78.51	0.00e+00	2190.00
IUUC-Mdo-063007	Monodelphis domestica	61.14	0.00e+00	1724.00
IUUC-Mmu-064067	Mus musculus	75.08	0.00e+00	2115.00
IUUC-Mpu-066532	Mustela putorius furo	84.53	0.00e+00	2445.00
IUUC-Mlu-066982	Myotis lucifugus	81.40	0.00e+00	2220.00
IUUC-Ncr-068758	Neurospora crassa	22.94	7.00e-31	129.00
IUUC-Nle-070042	Nomascus leucogenys	85.62	0.00e+00	1892.00
IUUC-Opr-070397	Ochotona princeps	77.86	0.00e+00	2216.00
IUUC-Ocu-074274	Oryctolagus cuniculus	81.91	0.00e+00	2263.00
IUUC-Oga-088577	Otolemur garnettii	79.40	0.00e+00	2271.00
IUUC-Oar-090117	Ovis aries	82.47	0.00e+00	2330.00
IUUC-Ptr-090553	Pan troglodytes	81.14	0.00e+00	2235.00
IUUC-Pan-092559	Papio anubis	71.32	0.00e+00	1024.00
IUUC-Psi-093710	Pelodiscus sinensis	64.84	0.00e+00	1385.00
IUUC-Pab-098510	Pongo abelii	80.30	0.00e+00	2179.00
IUUC-Pop-099155	Populus trichocarpa	32.04	3.00e-100	360.00
IUUC-Pca-100323	Procavia capensis	69.68	0.00e+00	1297.00
IUUC-Pva-102895	Pteropus vampyrus	83.96	0.00e+00	2391.00
IUUC-Rno-105598	Rattus norvegicus	76.06	0.00e+00	2151.00
IUUC-Sha-107013	Sarcophilus harrisii	64.21	0.00e+00	1734.00
IUUC-Smo-109134	Selaginella moellendorffii	37.36	5.00e-138	485.00
IUUC-Sar-113261	Sorex araneus	74.16	0.00e+00	2101.00
IUUC-Tsy-118799	Tarsius syrichta	90.81	0.00e+00	857.00
IUUC-Tni-120316	Tetraodon nigroviridis	56.50	0.00e+00	786.00
IUUC-Tvi-122281	Trichoderma virens	23.75	2.00e-31	130.00
IUUC-Tme-127128	Tuber melanosporum	23.96	6.00e-31	129.00
IUUC-Tbe-127555	Tupaia belangeri	92.32	0.00e+00	1008.00
IUUC-Ttr-128722	Tursiops truncatus	85.30	0.00e+00	2413.00
IUUC-Vda-129957	Verticillium dahliae	23.91	3.00e-30	127.00
IUUC-Vpa-130392	Vicugna pacos	61.30	8.00e-168	583.00
IUUC-Vvi-131035	Vitis vinifera	34.35	8.00e-109	388.00
IUUC-Xtr-131789	Xenopus tropicalis	59.22	0.00e+00	985.00
IUUC-Yli-134437	Yarrowia lipolytica	25.67	1.00e-15	78.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence