iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006829

Ensembl Protein ID

AT2G01330.1

UniProt Accession

Q9ZU34; AIP11_ARATH

Genbank Protein ID

AAD14533.1; AEC05436.1; AEC05437.1

Protein Name

Actin-interacting protein 1-1

Genbank Nucleotide ID

AC006200; CP002685; CP002685

Gene Name

AIP1-1; At2g01330

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G01330	AT2G01330.1	AT2G01330.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-35	118.6	231	265
UBD/Beta-Prp	2.10e-55	188.9	54	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH++s++++++ +d +++++ s D++ kvW++ ++
   Q: 231  GHKGSIYAVSWsPDsKRVLTVSADKSAKVWEVAED 265
           8***********999****************9766 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD....rtikvwdlstgkcvhtlkghedsvls 99
           g+h   +t+  +sp+++++a++  +gt++vw +++g +l+       + v ++++s dg +++ +s D     +++ +  ++g ++  + gh+++vls
   Q: 54   GEHGYAVTVARYSPNGEWIASADVSGTVRVWGTHNGFVLKNEfRVLAGRVDDLQWSFDG-LRIVASGDgkgkSLVRSFAWDSGNTMGDFDGHSRRVLS 150
           66777899999*************************9977665999999*********9.9999999999999************************* PP
   S: 100  lsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsngke 194
           ++f p++  ++++ ++d  ++ +d +  +  +   ++h+ +vnc++++pdg  +++ s D++ +++d ktg+ + +l  + gh++s+y +s+++++k+
   Q: 151  CAFKPTRpFRIATCGEDFLVNFYDGPPFKFHS-SHREHSNFVNCIRYSPDGTKFITVSSDKKGMIYDGKTGDKVGELasEDGHKGSIYAVSWSPDSKR 247
           *****99789******************9999.*********************************************9777**************** PP
   S: 195  lvsgsldgtvklwdlq....tgecvrtlnght....dnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlqlhnssvisvavlsfgdnvlvl 282
           ++++s d++ k+w++      g++++tl   +    + +++  ++ ++++l+++s  g+ +++  d + +++   l++h ++v+s avl+ +++ +++
   Q: 248  VLTVSADKSAKVWEVAedgtIGSVIKTLSFMEsggaEDMLVGCLW-QNDHLITVSLGGTMSLFsaD-DMDKPPLLLSGHIKNVTSLAVLGENQKTILS 343
           ****************76664444555543334444666666677.67778899999999999765.6899999************************ PP
   S: 283  gsedskvniw 292
           +s d+ +  w
   Q: 344  CSYDGLIVKW 353
           **99988665 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins.

Protein Sequence
(Fasta)

MAKLLETFPC VPSTERGRGI LISGDSKSDT ILYCNGRSVF IRSLRQLQDV QVYGEHGYAV 60
TVARYSPNGE WIASADVSGT VRVWGTHNGF VLKNEFRVLA GRVDDLQWSF DGLRIVASGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCCCCAAC CCTTAATTTC CTCCTAAACT TTCTCCTCCT CTGAAGAAGA AGAAGAAGAA 60
GAAGAAGAAG AAATGACGCA CTCCTTCACC GATTCTTCCT ACCAACAATT CCACGATGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0042643--C:actomyosin, actin portion
GO:0030864--C:cortical actin cytoskeleton
GO:0051015--F:actin filament binding
GO:0030042--P:actin filament depolymerization
GO:0030836--P:positive regulation of actin filament depolymerization

KEGG

ath:AT2G01330

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006423	Arabidopsis lyrata	92.44	0.00e+00	1199.00
IUUC-Ago-007920	Ashbya gossypii	28.07	3.00e-64	239.00
IUUC-Afl-008471	Aspergillus flavus	30.66	1.00e-69	256.00
IUUC-Bci-013925	Botrytis cinerea	33.33	1.00e-88	320.00
IUUC-Bol-016043	Brassica oleracea	90.85	0.00e+00	1160.00
IUUC-Bra-017719	Brassica rapa	89.95	0.00e+00	1151.00
IUUC-Cel-018417	Caenorhabditis elegans	32.69	1.00e-87	316.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	32.67	5.00e-86	311.00
IUUC-Dse-031526	Dothistroma septosporum	31.42	3.00e-83	301.00
IUUC-Fox-037924	Fusarium oxysporum	33.22	3.00e-91	328.00
IUUC-Fso-038199	Fusarium solani	33.22	6.00e-91	327.00
IUUC-Ggr-039830	Gaeumannomyces graminis	31.69	2.00e-79	289.00
IUUC-Kpa-049183	Komagataella pastoris	33.60	8.00e-78	283.00
IUUC-Mor-056940	Magnaporthe oryzae	31.66	1.00e-78	286.00
IUUC-Mpo-057557	Magnaporthe poae	27.33	8.00e-56	210.00
IUUC-Ncr-068948	Neurospora crassa	31.98	4.00e-86	311.00
IUUC-Sce-106383	Saccharomyces cerevisiae	31.97	2.00e-71	263.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	32.03	3.00e-85	308.00
IUUC-Sar-113415	Sorex araneus	46.21	1.00e-31	130.00
IUUC-Sre-114900	Sporisorium reilianum	34.03	5.00e-91	327.00
IUUC-Tre-122076	Trichoderma reesei	30.78	2.00e-79	289.00
IUUC-Uma-129631	Ustilago maydis	34.35	7.00e-96	343.00
IUUC-Vda-129732	Verticillium dahliae	30.27	4.00e-70	258.00
IUUC-Yli-134335	Yarrowia lipolytica	31.43	3.00e-78	285.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence