iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093050

Ensembl Protein ID

ENSPSIP00000002674.1

UniProt Accession

K7F3R4; K7F3R4_PELSI

Genbank Protein ID

ENSPSIP00000002674

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01161486

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000002613.1	ENSPSIT00000002683.1	ENSPSIP00000002674.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-29	99.0	185	219
UBD/Beta-Prp	4.90e-46	157.3	57	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlrt 32
           gH  +v ++a+ +     l+++s D  +k+WD+r+
   Q: 185  GHRQEVLAVAWsPRyeYVLATASADSRVKLWDVRR 219
           8**********84333559*************986 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl.............lrsl.sgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghed 95
           ++++++g+ dg i ++d+++ +                s    h+  v +v++ p++  ++ ++s D+t+k+wd +t ++  +++  e 
   Q: 57   GRYMLSGGSDGIIVLYDLENFSRkpcytckaicsvgR-SHpDVHKFSVETVQWYPHDTgMFTSSSFDKTLKIWDTNTLQPADVFT-FEG 143
           7899999999999999999966677777777666422.22345555599999887766699999999999999999999999999.999 PP
   S: 96   svlslsfsp..sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtl.... 175
           +v+s ++sp  ++   +++G++   +++ dl++g+c++ +l+gh++ v  v+++p    +l+++s+D+ v+lWd+ +   +l tl    
   Q: 144  TVYSHHMSPvaTKhCLIAVGTKSPKVQLCDLKSGSCSQ-ILQGHRQEVLAVAWSPRYeYVLATASADSRVKLWDVrRASGCLITLdqhn 231
           99999999997554778899999999999999999999.99999999999999999988899999999999999964445777777777 PP
   S: 176  ...........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
                        +h+++v+ l f+s+g +l+++++d++ +lw+ ++ge  +tl 
   Q: 232  gekskasseaaNTAHNGRVNGLCFTSDGLHLLTIGTDNRMRLWNSSSGE--NTLV 284
           7777777777745599999999999999999999999999999999885..4444 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MLAFISARQA GLDDPLPLRP AGCPPRWVLS LELNKDRDVE RIHGSGVNTL DIEPIEGRYM 60
LSGGSDGIIV LYDLENFSRK PCYTCKAICS VGRSHPDVHK FSVETVQWYP HDTGMFTSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGGCTT TCATTTCGGC CCGCCAGGCC GGTCTCGACG ATCCGTTGCC GCTGCGCCCG 60
GCCGGCTGCC CCCCGAGGTG CANNNNNNNN NNNGCTGGCC CCGAGCCGTT TAGTCTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	32.29	1.00e-37	152.00
IUUC-Aml-002201	Ailuropoda melanoleuca	83.67	0.00e+00	702.00
IUUC-Atr-002784	Amborella trichopoda	40.69	6.00e-40	158.00
IUUC-Apl-003202	Anas platyrhynchos	86.52	0.00e+00	686.00
IUUC-Aca-004708	Anolis carolinensis	84.53	0.00e+00	630.00
IUUC-Aly-006144	Arabidopsis lyrata	35.55	1.00e-68	253.00
IUUC-Ath-007489	Arabidopsis thaliana	34.55	4.00e-63	235.00
IUUC-Acl-008195	Aspergillus clavatus	39.77	5.00e-44	171.00
IUUC-Afl-008406	Aspergillus flavus	36.84	2.00e-38	152.00
IUUC-Afu-008759	Aspergillus fumigatus	37.12	9.00e-41	160.00
IUUC-Ani-009380	Aspergillus nidulans	37.27	3.00e-40	159.00
IUUC-Ang-009820	Aspergillus niger	35.97	7.00e-38	150.00
IUUC-Aor-010092	Aspergillus oryzae	36.52	1.00e-43	170.00
IUUC-Ate-010491	Aspergillus terreus	38.43	5.00e-45	175.00
IUUC-Bta-012825	Bos taurus	83.21	0.00e+00	697.00
IUUC-Bci-013856	Botrytis cinerea	31.61	2.00e-53	202.00
IUUC-Bdi-014899	Brachypodium distachyon	32.61	2.00e-56	213.00
IUUC-Bol-015337	Brassica oleracea	34.23	1.00e-66	246.00
IUUC-Bra-018089	Brassica rapa	34.13	2.00e-65	242.00
IUUC-Cja-018725	Callithrix jacchus	81.91	0.00e+00	693.00
IUUC-Cfa-021162	Canis familiaris	84.17	0.00e+00	702.00
IUUC-Cpo-022190	Cavia porcellus	82.91	0.00e+00	696.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	35.37	5.00e-38	152.00
IUUC-Csa-023610	Chlorocebus sabaeus	82.16	0.00e+00	697.00
IUUC-Cho-024689	Choloepus hoffmanni	83.56	0.00e+00	654.00
IUUC-Cin-025324	Ciona intestinalis	41.33	6.00e-81	294.00
IUUC-Csv-026059	Ciona savignyi	37.53	2.00e-70	259.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	36.05	4.00e-41	162.00
IUUC-Cme-027182	Cyanidioschyzon merolae	26.83	5.00e-12	66.20
IUUC-Dre-028696	Danio rerio	74.31	0.00e+00	627.00
IUUC-Dno-029102	Dasypus novemcinctus	83.42	0.00e+00	701.00
IUUC-Dor-030361	Dipodomys ordii	67.59	2.00e-154	537.00
IUUC-Dse-031167	Dothistroma septosporum	30.98	8.00e-48	184.00
IUUC-Ete-032856	Echinops telfairi	68.84	3.00e-159	553.00
IUUC-Eca-033611	Equus caballus	84.66	1.00e-177	615.00
IUUC-Eeu-034583	Erinaceus europaeus	62.06	9.00e-137	479.00
IUUC-Fca-036481	Felis catus	82.41	0.00e+00	693.00
IUUC-Fal-037327	Ficedula albicollis	86.76	1.00e-180	624.00
IUUC-Fox-037684	Fusarium oxysporum	34.80	6.00e-45	174.00
IUUC-Fso-038306	Fusarium solani	36.91	6.00e-55	207.00
IUUC-Gmo-039043	Gadus morhua	69.87	1.00e-169	588.00
IUUC-Ggr-039783	Gaeumannomyces graminis	30.31	7.00e-40	158.00
IUUC-Gga-041085	Gallus gallus	90.26	0.00e+00	654.00
IUUC-Gac-042328	Gasterosteus aculeatus	69.15	2.00e-164	571.00
IUUC-Gma-043004	Glycine max	34.35	2.00e-57	216.00
IUUC-Ggo-045627	Gorilla gorilla	74.69	0.00e+00	628.00
IUUC-Hsa-046028	Homo sapiens	82.16	0.00e+00	697.00
IUUC-Hvu-047678	Hordeum vulgare	29.84	4.00e-32	131.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	81.91	0.00e+00	696.00
IUUC-Kpa-049386	Komagataella pastoris	29.70	5.00e-44	171.00
IUUC-Lch-050590	Latimeria chalumnae	79.94	2.00e-161	561.00
IUUC-Lpe-051725	Leersia perrieri	35.08	7.00e-39	154.00
IUUC-Loc-051788	Lepisosteus oculatus	77.61	0.00e+00	639.00
IUUC-Lma-053082	Leptosphaeria maculans	34.55	5.00e-55	208.00
IUUC-Laf-053809	Loxodonta africana	83.96	0.00e+00	706.00
IUUC-Mcc-054998	Macaca mulatta	83.75	2.00e-144	504.00
IUUC-Meu-055929	Macropus eugenii	79.95	0.00e+00	642.00
IUUC-Mor-057003	Magnaporthe oryzae	35.42	6.00e-49	188.00
IUUC-Mtr-057921	Medicago truncatula	32.49	3.00e-56	212.00
IUUC-Mga-059449	Meleagris gallopavo	69.71	2.00e-130	458.00
IUUC-Mmr-061609	Microcebus murinus	79.90	0.00e+00	646.00
IUUC-Mdo-062564	Monodelphis domestica	87.91	0.00e+00	730.00
IUUC-Mmu-063904	Mus musculus	81.20	0.00e+00	685.00
IUUC-Mac-064716	Musa acuminata	31.00	1.00e-50	193.00
IUUC-Mpu-066617	Mustela putorius furo	83.42	0.00e+00	695.00
IUUC-Mlu-067054	Myotis lucifugus	82.16	0.00e+00	694.00
IUUC-Nfi-068467	Neosartorya fischeri	37.65	4.00e-35	141.00
IUUC-Nle-069731	Nomascus leucogenys	82.16	0.00e+00	697.00
IUUC-Opr-070297	Ochotona princeps	59.49	2.00e-73	268.00
IUUC-Ont-072558	Oreochromis niloticus	71.89	1.00e-170	592.00
IUUC-Oan-072864	Ornithorhynchus anatinus	89.29	1.00e-26	109.00
IUUC-Ocu-074415	Oryctolagus cuniculus	82.66	0.00e+00	700.00
IUUC-Oba-075759	Oryza barthii	30.46	2.00e-44	173.00
IUUC-Obr-076387	Oryza brachyantha	30.57	2.00e-46	179.00
IUUC-Ogl-077924	Oryza glaberrima	42.22	1.00e-19	89.00
IUUC-Ogu-078186	Oryza glumaepatula	34.55	6.00e-65	241.00
IUUC-Oin-079389	Oryza indica	35.01	5.00e-50	191.00
IUUC-Olo-080916	Oryza longistaminata	32.58	4.00e-17	80.50
IUUC-Ome-081471	Oryza meridionalis	39.69	4.00e-40	158.00
IUUC-Oni-082449	Oryza nivara	37.38	1.00e-40	160.00
IUUC-Opu-083210	Oryza punctata	32.69	2.00e-59	222.00
IUUC-Oru-085159	Oryza rufipogon	30.46	1.00e-44	173.00
IUUC-Osa-085926	Oryza sativa	43.92	1.00e-33	135.00
IUUC-Ola-087084	Oryzias latipes	70.71	1.00e-173	602.00
IUUC-Olu-087853	Ostreococcus lucimarinus	30.40	1.00e-41	163.00
IUUC-Oga-089008	Otolemur garnettii	81.25	0.00e+00	697.00
IUUC-Oar-089259	Ovis aries	83.46	0.00e+00	696.00
IUUC-Ptr-091112	Pan troglodytes	81.77	0.00e+00	688.00
IUUC-Pan-092303	Papio anubis	79.69	2.00e-60	223.00
IUUC-Pma-094259	Petromyzon marinus	57.28	6.00e-125	440.00
IUUC-Pno-094798	Phaeosphaeria nodorum	33.24	1.00e-51	196.00
IUUC-Ppa-095477	Physcomitrella patens	30.20	9.00e-52	197.00
IUUC-Pfo-096855	Poecilia formosa	69.98	2.00e-170	591.00
IUUC-Pab-098096	Pongo abelii	81.66	0.00e+00	692.00
IUUC-Pop-098800	Populus trichocarpa	33.33	5.00e-69	254.00
IUUC-Pca-100187	Procavia capensis	85.92	2.00e-106	378.00
IUUC-Ppe-101759	Prunus persica	37.61	2.00e-43	169.00
IUUC-Pva-102438	Pteropus vampyrus	69.42	6.00e-80	290.00
IUUC-Pte-104197	Pyrenophora teres	33.05	9.00e-50	190.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	34.18	1.00e-50	193.00
IUUC-Rno-106087	Rattus norvegicus	81.20	0.00e+00	689.00
IUUC-Sce-106276	Saccharomyces cerevisiae	24.74	4.00e-12	65.90
IUUC-Sha-106831	Sarcophilus harrisii	82.96	0.00e+00	688.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	32.84	1.00e-53	203.00
IUUC-Spo-108294	Schizosaccharomyces pombe	37.15	5.00e-65	241.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	32.30	6.00e-51	194.00
IUUC-Smo-109008	Selaginella moellendorffii	38.01	1.00e-71	263.00
IUUC-Sit-110300	Setaria italica	31.54	3.00e-55	208.00
IUUC-Sly-111441	Solanum lycopersicum	34.88	2.00e-58	219.00
IUUC-Stu-111995	Solanum tuberosum	34.63	3.00e-59	222.00
IUUC-Sar-113196	Sorex araneus	74.52	6.00e-115	407.00
IUUC-Sbi-113790	Sorghum bicolor	31.22	5.00e-46	178.00
IUUC-Ssc-115609	Sus scrofa	83.67	0.00e+00	701.00
IUUC-Tgu-116927	Taeniopygia guttata	85.50	0.00e+00	702.00
IUUC-Tru-118164	Takifugu rubripes	71.64	2.00e-178	618.00
IUUC-Tsy-119151	Tarsius syrichta	76.63	0.00e+00	640.00
IUUC-Tni-120896	Tetraodon nigroviridis	70.57	1.00e-168	585.00
IUUC-Tca-121592	Theobroma cacao	36.51	5.00e-43	168.00
IUUC-Tre-122023	Trichoderma reesei	34.95	8.00e-51	194.00
IUUC-Tvi-122507	Trichoderma virens	34.76	2.00e-52	199.00
IUUC-Tae-125730	Triticum aestivum	40.82	3.00e-42	165.00
IUUC-Tur-126092	Triticum urartu	32.25	2.00e-35	143.00
IUUC-Tbe-127422	Tupaia belangeri	63.61	2.00e-134	471.00
IUUC-Ttr-129097	Tursiops truncatus	81.66	0.00e+00	690.00
IUUC-Vda-130014	Verticillium dahliae	39.50	3.00e-52	199.00
IUUC-Vpa-130782	Vicugna pacos	82.71	0.00e+00	695.00
IUUC-Vvi-131494	Vitis vinifera	37.39	5.00e-43	168.00
IUUC-Xtr-132165	Xenopus tropicalis	80.05	0.00e+00	636.00
IUUC-Xma-133205	Xiphophorus maculatus	70.65	1.00e-173	602.00
IUUC-Yli-134614	Yarrowia lipolytica	33.89	5.00e-57	214.00
IUUC-Zma-135861	Zea mays	35.71	7.00e-63	234.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence