iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111717

Ensembl Protein ID

Solyc12g088630.1.1

UniProt Accession

K4DGT4; K4DGT4_SOLLC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc12g088630.1	Solyc12g088630.1.1	Solyc12g088630.1.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-48	159.7	345	383
UBD/Beta-Prp	1.90e-79	267.7	225	505

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++ ++++++ ++  ll+s+s D t+k+W+++++v+l+
   Q: 345  GHKNAINAIKWdPSgSLLASCSEDTTVKIWSMKRDVCLH 383
           8***********6669*********************97 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
            + +t +++ ++++llatgs+dg  ++w  +  +l+++l +he+++ +vk++++g++l++gs+Drt+ vw++++g+  + +   ++  l+ 
   Q: 225  ND-VTTLDWNRKGTLLATGSYDGQARIWTRSG-SLFQTLNKHEGTIFSVKWNKKGDYLLSGSTDRTAVVWNVKSGELKQQFC-FNAGFLDA 312
           33.5559*********************7665.999**********************************************.88888888 PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsn 191
           ++   ++++++Gs d+ + + ++  +q ++  +sgh+ ++n ++++p+g+ll+s+s D+tv++W++k++ +l+ +++ h + ++ + ++++
   Q: 313  DWLD-NNSFAIGSTDNKVYICKVGVNQPVK-RFSGHKNAINAIKWDPSGSLLASCSEDTTVKIWSMKRDVCLHNFRE-HSKEINTVRWSPT 400
           8888.899**********************.*********************************************9.************* PP
   S: 192  g.........kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
           g           l+s+s d+tvklwd+++g+ +++lngh++ v+sv+fspn+++l+sgs D+  +iW ++  +++kt+       i   ++
   Q: 401  GagtsnpnkkLLLASASFDSTVKLWDIERGRLLHSLNGHREVVYSVAFSPNGDYLASGSLDKRMNIWSVKEAKIVKTYHTDG--GIFNVCW 489
           9*******988899**************************************************************998744..4444444 PP
   S: 274  sfgdnvlvlgsedskvn 290
           + ++n+++++ + +kv 
   Q: 490  NKEGNKVAACFS-NKVF 505
           555555444433.2444 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MASLTSDLLN FIVFRYLQES GFIHAAFSFG YEAGLNRSSI DGRLIPINAL IKIVQKGLQY 60
LELETNLSID DTDMDEDFRF VEPFDLITKS VSELQQMIKE EKEKVRKDKA NADNELDHER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTCTT TAACCTCCGA CCTGTTGAAT TTCATCGTCT TCCGGTACCT CCAGGAATCA 60
GGTAATTCAA TTTTCCTTTT CAGAACATGT ACAATCTTGT AGGATTCAAA TGATAGTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

sly:101257249

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024872	Choloepus hoffmanni	37.96	2.00e-34	139.00
IUUC-Mac-065508	Musa acuminata	53.76	2.00e-129	455.00
IUUC-Oin-079515	Oryza indica	51.01	4.00e-118	418.00
IUUC-Sja-107844	Schizosaccharomyces japonicus	26.37	4.00e-32	132.00
IUUC-Stu-112786	Solanum tuberosum	86.50	0.00e+00	907.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence