iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117862

UUCD1 version

UUC-TaR-00497

Ensembl Protein ID

ENSTRUP00000024439.1

UniProt Accession

H2TID7; H2TID7_TAKRU

Protein Name

Uncharacterized protein

Gene Name

tbl1x; LOC101062383

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009728.1	ENSTRUT00000024538.1	ENSTRUP00000024439.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-53	177.1	442	478
UBD/Beta-Prp	2.10e-64	218.8	164	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H+++v+++af +d ++l+sGs D+ +++W+++tg l+
   Q: 442  HQEPVYSVAFsPDgKHLASGSFDKCVHIWNTTTGALV 478
           9**********999*******************9876 PP

UBD/Beta-Prp

   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.............tlsghdgvvncvvvhpdgnllvsGslDrtvrl 163
            +l+ghe++v  ++++p +d l+sGs d+t+r+w+l+++  +++              + + ++ v+++ +++dg ll++Gs+D++ r+
   Q: 164  TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENNNSNStqlvlrhcireggQDVPSNKDVTSLDWNSDGTLLATGSYDGFARI 252
           5789**************************************999************89999999************************ PP
   S: 164  WdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
           W  k g+l  tl + h++++  l+++++g++++s++ d+t ++wd +tge  +++  h+++ ++v+   n++ ++s+s D  i +  l 
   Q: 253  W-TKDGNLASTLGQ-HKGPIFALKWNKKGNSILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCRLG 338
           *.88********76.**************************************************988.99****************** PP
   S: 253  sgdllktlqlh 263
           s+ +lkt+q+h
   Q: 339  SDRPLKTFQGH 349
           *********98 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

AKMSITSDEV NFLVYRYLQE SGFSHSAFTF GIESHISQSN INGTLVPPAA LISILQKGLQ 60
YVEAEISINE DGTVFDGRPI ESLSLIDAVM PDVVQTRQQA FRDKLAQQQV ANATAASSSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTAAGATGA GTATTACCAG TGACGAAGTC AACTTCTTGG TCTACAGATA CCTTCAGGAA 60
TCAGGTTTGT GTCACTTCTG CTCTGCTATA AGCTGTGGGG GCATGTTATA TTACCAACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	91.26	0.00e+00	942.00
IUUC-Apl-003232	Anas platyrhynchos	90.06	0.00e+00	947.00
IUUC-Aca-005035	Anolis carolinensis	89.22	0.00e+00	959.00
IUUC-Ago-007869	Ashbya gossypii	25.10	5.00e-37	149.00
IUUC-Bta-013202	Bos taurus	89.58	0.00e+00	946.00
IUUC-Cja-019281	Callithrix jacchus	89.40	0.00e+00	936.00
IUUC-Cfa-020929	Canis familiaris	89.54	0.00e+00	941.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.75	4.00e-130	458.00
IUUC-Csa-023943	Chlorocebus sabaeus	88.72	0.00e+00	937.00
IUUC-Csv-026257	Ciona savignyi	71.32	0.00e+00	763.00
IUUC-Cme-027258	Cyanidioschyzon merolae	39.62	4.00e-106	378.00
IUUC-Ete-032822	Echinops telfairi	80.54	0.00e+00	800.00
IUUC-Eca-033897	Equus caballus	89.73	0.00e+00	946.00
IUUC-Fca-036462	Felis catus	89.18	0.00e+00	942.00
IUUC-Fal-037388	Ficedula albicollis	90.82	0.00e+00	952.00
IUUC-Gga-040671	Gallus gallus	90.82	0.00e+00	952.00
IUUC-Gac-041851	Gasterosteus aculeatus	96.49	0.00e+00	985.00
IUUC-Gma-044208	Glycine max	47.64	2.00e-151	528.00
IUUC-Ggo-045373	Gorilla gorilla	87.71	0.00e+00	937.00
IUUC-Hsa-045841	Homo sapiens	88.45	0.00e+00	938.00
IUUC-Kpa-049338	Komagataella pastoris	28.91	6.00e-32	132.00
IUUC-Lch-050535	Latimeria chalumnae	92.20	0.00e+00	954.00
IUUC-Laf-054071	Loxodonta africana	89.04	0.00e+00	944.00
IUUC-Mga-059895	Meleagris gallopavo	90.65	0.00e+00	952.00
IUUC-Mmr-061286	Microcebus murinus	89.25	0.00e+00	948.00
IUUC-Mmu-063447	Mus musculus	89.75	0.00e+00	946.00
IUUC-Mac-065508	Musa acuminata	45.73	2.00e-107	382.00
IUUC-Nle-069151	Nomascus leucogenys	88.40	0.00e+00	934.00
IUUC-Ont-072252	Oreochromis niloticus	96.10	0.00e+00	1008.00
IUUC-Oan-073562	Ornithorhynchus anatinus	89.75	0.00e+00	947.00
IUUC-Opu-083505	Oryza punctata	48.11	7.00e-143	500.00
IUUC-Olu-087589	Ostreococcus lucimarinus	52.16	1.00e-156	546.00
IUUC-Oar-089506	Ovis aries	91.81	0.00e+00	949.00
IUUC-Pan-091909	Papio anubis	88.80	0.00e+00	938.00
IUUC-Psi-093358	Pelodiscus sinensis	88.74	0.00e+00	906.00
IUUC-Pfo-097214	Poecilia formosa	94.35	0.00e+00	964.00
IUUC-Ppe-101572	Prunus persica	50.89	8.00e-144	503.00
IUUC-Rno-105857	Rattus norvegicus	89.75	0.00e+00	946.00
IUUC-Sha-107326	Sarcophilus harrisii	91.42	0.00e+00	960.00
IUUC-Sja-107844	Schizosaccharomyces japonicus	24.05	7.00e-27	115.00
IUUC-Stu-112786	Solanum tuberosum	48.95	2.00e-141	496.00
IUUC-Ssc-115646	Sus scrofa	89.45	0.00e+00	952.00
IUUC-Tgu-116898	Taeniopygia guttata	90.25	0.00e+00	950.00
IUUC-Tni-119656	Tetraodon nigroviridis	98.45	0.00e+00	1004.00
IUUC-Tae-125368	Triticum aestivum	49.28	4.00e-151	528.00
IUUC-Tur-126856	Triticum urartu	42.16	2.00e-74	273.00
IUUC-Ttr-128826	Tursiops truncatus	90.25	0.00e+00	875.00
IUUC-Xma-133591	Xiphophorus maculatus	94.95	0.00e+00	969.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence