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Tag Content
iUUCD ID IUUC-Aca-004305
Ensembl Protein ID ENSACAP00000004192.3
UniProt Accession H9G8S9; H9G8S9_ANOCA
Protein Name Uncharacterized protein
Gene Name MDM2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSACAG00000004204.3 ENSACAT00000004291.3 ENSACAP00000004192.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 59.57 2.00e-117 420.00 IUUC-Hsa-046376
E3 activity/RING/RING 52.72 2.00e-97 353.00 IUUC-Mmu-063207
E3 activity/RING/RING 55.58 4.00e-106 382.00 IUUC-Rno-105641
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Anolis carolinensis
Protein Sequence
(Fasta)
MASALEPAAA GTSGSSGTSQ ETLVKPKPLL LKLLKFAGAQ KDTFTMKEIL LYIGQYIMSK 60
HLYDEKQQHI VHCANDLLGE LFGVQSFSIK EQRQLYMMIS KNLVTVSRQD NVNTTVNQSR 120
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Protein Fasta Sequence



>IUUC-Aca-004305|E3,RING|Anolis carolinensis
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Nucleotide Sequence
(Fasta)
CACCTCCCAA CAAAGAATTC CCCCAGTCAG GAAGCGGGCA GGCTTTGAAG CTGCAAGGCC 60
ATCCAATGCT AATCAAGCTG GCTAATTGCA ACATTCACAC TTGCCTCCAA CAGACAAGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Aca-004305|E3,RING|Anolis carolinensis
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0003283--P:atrial septum development
GO:0003181--P:atrioventricular valve morphogenesis
GO:0001568--P:blood vessel development
GO:0001974--P:blood vessel remodeling
GO:0060411--P:cardiac septum morphogenesis
GO:0071456--P:cellular response to hypoxia
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0003203--P:endocardial cushion morphogenesis
GO:0045184--P:establishment of protein localization
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0018205--P:peptidyl-lysine modification
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006461--P:protein complex assembly
GO:0031648--P:protein destabilization
GO:0034504--P:protein localization to nucleus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0002027--P:regulation of heart rate
GO:0046677--P:response to antibiotic
GO:0007089--P:traversing start control point of mitotic cell cycle
GO:0003281--P:ventricular septum development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002039 Ailuropoda melanoleuca 59.62 9.00e-130 456.00
IUUC-Apl-003193 Anas platyrhynchos 62.08 7.00e-128 450.00
IUUC-Ame-010675 Astyanax mexicanus 46.61 1.00e-73 270.00
IUUC-Bta-013270 Bos taurus 58.55 2.00e-123 435.00
IUUC-Cja-019744 Callithrix jacchus 59.20 2.00e-125 442.00
IUUC-Cfa-020807 Canis familiaris 57.82 4.00e-119 421.00
IUUC-Cpo-022182 Cavia porcellus 58.03 2.00e-117 415.00
IUUC-Csa-023541 Chlorocebus sabaeus 60.38 1.00e-124 439.00
IUUC-Cho-024831 Choloepus hoffmanni 50.19 3.00e-47 181.00
IUUC-Csv-026151 Ciona savignyi 30.11 7.00e-13 67.00
IUUC-Dre-028419 Danio rerio 45.34 2.00e-70 259.00
IUUC-Dno-028950 Dasypus novemcinctus 58.90 1.00e-124 439.00
IUUC-Dor-031048 Dipodomys ordii 52.14 2.00e-46 179.00
IUUC-Ete-032264 Echinops telfairi 49.79 2.00e-57 216.00
IUUC-Eca-033301 Equus caballus 56.75 1.00e-119 423.00
IUUC-Eeu-035005 Erinaceus europaeus 52.33 2.00e-95 342.00
IUUC-Fca-035454 Felis catus 57.11 5.00e-121 427.00
IUUC-Fal-036720 Ficedula albicollis 65.12 8.00e-66 243.00
IUUC-Gmo-039296 Gadus morhua 42.32 2.00e-35 142.00
IUUC-Gga-040251 Gallus gallus 61.42 2.00e-123 435.00
IUUC-Ggo-044948 Gorilla gorilla 56.63 3.00e-114 405.00
IUUC-Hsa-046376 Homo sapiens 60.81 3.00e-126 444.00
IUUC-Itr-048328 Ictidomys tridecemlineatus 59.11 1.00e-119 422.00
IUUC-Lch-050037 Latimeria chalumnae 53.44 2.00e-91 329.00
IUUC-Loc-051837 Lepisosteus oculatus 50.00 2.00e-98 352.00
IUUC-Laf-053483 Loxodonta africana 54.09 7.00e-124 437.00
IUUC-Mcc-055294 Macaca mulatta 60.38 4.00e-125 441.00
IUUC-Mga-060007 Meleagris gallopavo 60.32 5.00e-113 400.00
IUUC-Mmr-060673 Microcebus murinus 59.36 2.00e-126 446.00
IUUC-Mdo-063057 Monodelphis domestica 59.14 1.00e-128 452.00
IUUC-Mmu-063207 Mus musculus 50.32 1.00e-98 353.00
IUUC-Mpu-065836 Mustela putorius furo 56.75 1.00e-124 439.00
IUUC-Mlu-068193 Myotis lucifugus 55.77 5.00e-113 401.00
IUUC-Nle-069927 Nomascus leucogenys 60.38 3.00e-125 441.00
IUUC-Opr-070590 Ochotona princeps 54.06 1.00e-101 363.00
IUUC-Ont-071984 Oreochromis niloticus 41.55 1.00e-64 240.00
IUUC-Oan-072744 Ornithorhynchus anatinus 60.47 3.00e-120 425.00
IUUC-Ocu-074071 Oryctolagus cuniculus 57.63 2.00e-117 416.00
IUUC-Ola-087329 Oryzias latipes 36.80 1.00e-46 180.00
IUUC-Oga-088135 Otolemur garnettii 54.45 4.00e-112 398.00
IUUC-Oar-090078 Ovis aries 59.83 8.00e-129 453.00
IUUC-Ptr-091399 Pan troglodytes 60.59 1.00e-125 443.00
IUUC-Pan-092720 Papio anubis 60.38 4.00e-125 441.00
IUUC-Psi-093591 Pelodiscus sinensis 63.13 4.00e-64 238.00
IUUC-Pfo-096316 Poecilia formosa 40.75 8.00e-70 257.00
IUUC-Pab-097696 Pongo abelii 60.59 3.00e-124 438.00
IUUC-Pca-100974 Procavia capensis 52.75 8.00e-122 430.00
IUUC-Pva-102488 Pteropus vampyrus 51.50 2.00e-104 372.00
IUUC-Rno-105641 Rattus norvegicus 55.25 2.00e-108 385.00
IUUC-Sce-106414 Saccharomyces cerevisiae 28.57 1.70e-01 31.20
IUUC-Sha-107314 Sarcophilus harrisii 58.71 7.00e-130 457.00
IUUC-Sar-112938 Sorex araneus 55.84 5.00e-118 417.00
IUUC-Ssc-115495 Sus scrofa 57.42 3.00e-123 435.00
IUUC-Tgu-116623 Taeniopygia guttata 61.33 2.00e-120 425.00
IUUC-Tru-117820 Takifugu rubripes 41.39 5.00e-67 248.00
IUUC-Tsy-119162 Tarsius syrichta 40.73 2.00e-30 126.00
IUUC-Tbe-127816 Tupaia belangeri 59.15 6.00e-63 234.00
IUUC-Ttr-129194 Tursiops truncatus 58.24 1.00e-97 350.00
IUUC-Vpa-130326 Vicugna pacos 52.98 2.00e-104 372.00
IUUC-Xtr-132216 Xenopus tropicalis 54.04 4.00e-107 381.00
Created Date 25-Jun-2017

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