iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-021008

Ensembl Protein ID

ENSCAFP00000037556.1

UniProt Accession

J9NWL1; J9NWL1_CANLF

Genbank Protein ID

ENSCAFP00000037556

Protein Name

SUMO-conjugating enzyme

Genbank Nucleotide ID

AAEX03004652

Gene Name

UBE2I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000031449.1	ENSCAFT00000048668.1	ENSCAFP00000037556.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.10e-35	120.1	8	112

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdppegisakpvdesd....ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsi 85
           Rl++e k+++kd+p g++a p+++ d    l++we++i G+++tp+egg+Fkl++ f++dYP++PPk+kf+ ++fhPnvy++G+vClsi
   Q: 8    RLAQERKAWRKDHPFGFVAVPTKNPDgtmnLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSI 96
           99*****************99998877777*********************************************************** PP
   S: 86   lkeeekWspalsvesv 101
           l+e+++W+pa+++++v
   Q: 97   LEEDKDWRPAITIKQV 112
           **************98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL 60
RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED KDWRPAITIK QVGRQGARGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGAGGGG TCGCAGTGCT GCGCCCATTT CACAGATGAG ACCGAAACCG TCCGGACGGG 60
AGATGAGTGC CTAGCCCAAA CCCCGGCAGC CAGGGCAGCC AGGAAGCGGC TCTGAGGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR027230--Ubc9
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:1990234--C:transferase complex
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0061656--F:SUMO conjugating enzyme activity
GO:0019789--F:SUMO transferase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1903755--P:positive regulation of SUMO transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002383	Ailuropoda melanoleuca	99.11	7.00e-65	239.00
IUUC-Atr-002982	Amborella trichopoda	69.09	5.00e-34	136.00
IUUC-Apl-003840	Anas platyrhynchos	99.11	6.00e-65	239.00
IUUC-Aca-004772	Anolis carolinensis	99.11	7.00e-65	239.00
IUUC-Aly-005652	Arabidopsis lyrata	70.27	1.00e-43	168.00
IUUC-Ath-007084	Arabidopsis thaliana	70.27	1.00e-43	168.00
IUUC-Ago-007998	Ashbya gossypii	59.82	5.00e-40	156.00
IUUC-Acl-008040	Aspergillus clavatus	65.74	2.00e-41	161.00
IUUC-Afl-008563	Aspergillus flavus	63.89	6.00e-41	159.00
IUUC-Afu-008873	Aspergillus fumigatus	69.07	6.00e-39	153.00
IUUC-Ani-009222	Aspergillus nidulans	66.67	8.00e-42	162.00
IUUC-Ang-009740	Aspergillus niger	70.41	8.00e-40	156.00
IUUC-Aor-010170	Aspergillus oryzae	64.81	3.00e-41	160.00
IUUC-Ate-010410	Aspergillus terreus	67.59	3.00e-42	164.00
IUUC-Ame-011664	Astyanax mexicanus	100.00	6.00e-65	239.00
IUUC-Bgr-012012	Blumeria graminis	60.00	4.00e-36	143.00
IUUC-Bta-013269	Bos taurus	99.11	7.00e-65	239.00
IUUC-Bci-013748	Botrytis cinerea	66.36	7.00e-35	139.00
IUUC-Bdi-014273	Brachypodium distachyon	70.00	7.00e-43	166.00
IUUC-Bol-016125	Brassica oleracea	71.17	2.00e-35	141.00
IUUC-Bra-017235	Brassica rapa	71.17	2.00e-35	141.00
IUUC-Cel-018448	Caenorhabditis elegans	77.68	1.00e-53	202.00
IUUC-Cja-019349	Callithrix jacchus	99.11	7.00e-65	239.00
IUUC-Cpo-021324	Cavia porcellus	99.11	7.00e-65	239.00
IUUC-Cre-022836	Chlamydomonas reinhardtii	66.07	1.00e-42	165.00
IUUC-Csa-024207	Chlorocebus sabaeus	99.11	7.00e-65	239.00
IUUC-Cin-025734	Ciona intestinalis	84.82	6.00e-58	216.00
IUUC-Csv-026049	Ciona savignyi	82.14	3.00e-56	210.00
IUUC-Cgl-026699	Colletotrichum gloeosporioides	65.14	5.00e-40	156.00
IUUC-Cne-027034	Cryptococcus neoformans	66.07	7.00e-46	176.00
IUUC-Cme-027203	Cyanidioschyzon merolae	63.39	4.00e-41	160.00
IUUC-Dre-027701	Danio rerio	99.11	8.00e-65	238.00
IUUC-Dno-030037	Dasypus novemcinctus	99.11	7.00e-65	239.00
IUUC-Dor-030622	Dipodomys ordii	97.32	3.00e-63	233.00
IUUC-Dse-031366	Dothistroma septosporum	66.36	3.00e-43	167.00
IUUC-Dme-031818	Drosophila melanogaster	85.71	3.00e-58	217.00
IUUC-Ete-032517	Echinops telfairi	99.11	2.00e-64	237.00
IUUC-Eca-033789	Equus caballus	99.11	7.00e-65	239.00
IUUC-Fca-035851	Felis catus	99.11	7.00e-65	239.00
IUUC-Fal-037177	Ficedula albicollis	99.11	6.00e-65	239.00
IUUC-Fox-037789	Fusarium oxysporum	62.73	8.00e-42	162.00
IUUC-Fso-038166	Fusarium solani	62.73	2.00e-41	160.00
IUUC-Gmo-039482	Gadus morhua	99.11	7.00e-65	239.00
IUUC-Ggr-039892	Gaeumannomyces graminis	65.45	4.00e-42	164.00
IUUC-Gga-041199	Gallus gallus	99.11	7.00e-65	239.00
IUUC-Gac-042250	Gasterosteus aculeatus	99.11	7.00e-65	239.00
IUUC-Gma-043827	Glycine max	71.43	7.00e-45	172.00
IUUC-Ggo-045530	Gorilla gorilla	99.11	7.00e-65	239.00
IUUC-Hsa-046248	Homo sapiens	99.11	7.00e-65	239.00
IUUC-Hvu-047363	Hordeum vulgare	67.27	7.00e-42	162.00
IUUC-Itr-048429	Ictidomys tridecemlineatus	99.11	7.00e-65	239.00
IUUC-Kpa-049362	Komagataella pastoris	60.71	5.00e-40	156.00
IUUC-Lch-050644	Latimeria chalumnae	95.54	2.00e-63	234.00
IUUC-Lpe-051643	Leersia perrieri	70.91	5.00e-44	170.00
IUUC-Loc-052357	Lepisosteus oculatus	99.11	7.00e-65	239.00
IUUC-Lma-053142	Leptosphaeria maculans	63.30	4.00e-42	163.00
IUUC-Laf-053577	Loxodonta africana	99.11	7.00e-65	239.00
IUUC-Mcc-054925	Macaca mulatta	99.11	7.00e-65	239.00
IUUC-Meu-056094	Macropus eugenii	76.79	2.00e-45	174.00
IUUC-Mor-057141	Magnaporthe oryzae	62.73	2.00e-41	161.00
IUUC-Mpo-057613	Magnaporthe poae	65.45	8.00e-42	162.00
IUUC-Mtr-058465	Medicago truncatula	71.43	2.00e-46	177.00
IUUC-Mla-059115	Melampsora laricipopulina	67.86	1.00e-45	175.00
IUUC-Mga-059384	Meleagris gallopavo	99.11	7.00e-65	239.00
IUUC-Mvi-060328	Microbotryum violaceum	63.96	7.00e-40	155.00
IUUC-Mmr-061541	Microcebus murinus	99.11	7.00e-65	239.00
IUUC-Mdo-062540	Monodelphis domestica	99.11	7.00e-65	239.00
IUUC-Mmu-063818	Mus musculus	99.11	7.00e-65	239.00
IUUC-Mac-065019	Musa acuminata	70.00	1.00e-43	168.00
IUUC-Mpu-065734	Mustela putorius furo	99.11	7.00e-65	239.00
IUUC-Mlu-067619	Myotis lucifugus	99.11	7.00e-65	239.00
IUUC-Nfi-068567	Neosartorya fischeri	66.67	3.00e-42	164.00
IUUC-Ncr-068897	Neurospora crassa	66.36	2.00e-42	164.00
IUUC-Nle-069541	Nomascus leucogenys	99.10	3.00e-64	236.00
IUUC-Ont-071585	Oreochromis niloticus	99.11	7.00e-65	239.00
IUUC-Oan-073178	Ornithorhynchus anatinus	100.00	6.00e-42	161.00
IUUC-Ocu-074588	Oryctolagus cuniculus	88.39	1.00e-54	205.00
IUUC-Oba-075371	Oryza barthii	70.00	6.00e-43	166.00
IUUC-Obr-076199	Oryza brachyantha	70.00	4.00e-43	166.00
IUUC-Ogl-077506	Oryza glaberrima	70.00	6.00e-43	166.00
IUUC-Ogu-078474	Oryza glumaepatula	70.00	6.00e-43	166.00
IUUC-Oin-080036	Oryza indica	70.00	6.00e-43	166.00
IUUC-Olo-080940	Oryza longistaminata	60.91	9.00e-37	145.00
IUUC-Ome-081909	Oryza meridionalis	68.18	2.00e-42	165.00
IUUC-Oni-082340	Oryza nivara	70.00	6.00e-43	166.00
IUUC-Opu-083206	Oryza punctata	70.00	4.00e-43	167.00
IUUC-Oru-084239	Oryza rufipogon	70.00	6.00e-43	166.00
IUUC-Osa-086213	Oryza sativa	70.00	6.00e-43	166.00
IUUC-Ola-086314	Oryzias latipes	95.54	5.00e-63	233.00
IUUC-Olu-087715	Ostreococcus lucimarinus	54.31	1.00e-33	135.00
IUUC-Oga-088729	Otolemur garnettii	99.11	1.00e-64	238.00
IUUC-Oar-090221	Ovis aries	99.11	2.00e-64	238.00
IUUC-Ptr-090528	Pan troglodytes	99.11	7.00e-65	239.00
IUUC-Pan-092834	Papio anubis	99.11	7.00e-65	239.00
IUUC-Psi-093001	Pelodiscus sinensis	99.11	7.00e-65	239.00
IUUC-Pma-094539	Petromyzon marinus	95.54	1.00e-63	234.00
IUUC-Pno-094954	Phaeosphaeria nodorum	63.72	8.00e-42	162.00
IUUC-Ppa-095314	Physcomitrella patens	66.36	7.00e-42	162.00
IUUC-Pfo-097457	Poecilia formosa	99.11	5.00e-65	239.00
IUUC-Pab-098205	Pongo abelii	99.11	7.00e-65	239.00
IUUC-Pop-099063	Populus trichocarpa	70.00	1.00e-43	168.00
IUUC-Pca-100603	Procavia capensis	99.11	7.00e-64	236.00
IUUC-Ppe-101501	Prunus persica	70.91	2.00e-34	137.00
IUUC-Pva-103251	Pteropus vampyrus	74.11	2.00e-43	167.00
IUUC-Pte-104067	Pyrenophora teres	61.82	8.00e-42	162.00
IUUC-Pyt-104436	Pyrenophora triticirepentis	62.73	4.00e-42	163.00
IUUC-Rno-105794	Rattus norvegicus	99.11	7.00e-65	239.00
IUUC-Sce-106308	Saccharomyces cerevisiae	60.71	3.00e-40	157.00
IUUC-Sha-106997	Sarcophilus harrisii	87.39	4.00e-55	206.00
IUUC-Sja-108000	Schizosaccharomyces japonicus	69.09	2.00e-44	171.00
IUUC-Spo-108311	Schizosaccharomyces pombe	65.45	5.00e-42	163.00
IUUC-Smo-108685	Selaginella moellendorffii	70.00	7.00e-35	139.00
IUUC-Sit-109792	Setaria italica	70.91	8.00e-44	169.00
IUUC-Sly-111886	Solanum lycopersicum	69.09	4.00e-33	133.00
IUUC-Stu-111975	Solanum tuberosum	69.37	6.00e-44	169.00
IUUC-Sbi-114672	Sorghum bicolor	70.91	8.00e-44	169.00
IUUC-Sre-114957	Sporisorium reilianum	73.21	4.00e-49	186.00
IUUC-Ssc-116173	Sus scrofa	99.11	7.00e-65	239.00
IUUC-Tgu-116668	Taeniopygia guttata	99.11	7.00e-65	239.00
IUUC-Tru-118365	Takifugu rubripes	96.43	3.00e-63	233.00
IUUC-Tni-120455	Tetraodon nigroviridis	94.64	2.00e-62	230.00
IUUC-Tca-120956	Theobroma cacao	70.00	6.00e-43	166.00
IUUC-Tre-121927	Trichoderma reesei	64.55	9.00e-43	165.00
IUUC-Tvi-122363	Trichoderma virens	64.55	1.00e-42	165.00
IUUC-Tae-125311	Triticum aestivum	70.00	4.00e-43	166.00
IUUC-Tur-126625	Triticum urartu	70.00	4.00e-43	166.00
IUUC-Tme-126981	Tuber melanosporum	55.56	2.00e-30	124.00
IUUC-Ttr-128280	Tursiops truncatus	98.39	1.00e-33	134.00
IUUC-Uma-129582	Ustilago maydis	73.21	9.00e-49	185.00
IUUC-Vda-129845	Verticillium dahliae	65.45	9.00e-43	165.00
IUUC-Vpa-130242	Vicugna pacos	99.11	3.00e-64	237.00
IUUC-Vvi-130948	Vitis vinifera	68.47	1.00e-42	165.00
IUUC-Xtr-132540	Xenopus tropicalis	99.11	9.00e-65	238.00
IUUC-Xma-133010	Xiphophorus maculatus	99.11	5.00e-65	239.00
IUUC-Yli-134673	Yarrowia lipolytica	55.24	4.00e-36	143.00
IUUC-Zma-135055	Zea mays	70.91	4.00e-44	170.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence