iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043354

UUCD1 version

UUC-GlM-02893

Ensembl Protein ID

GLYMA04G43440.2

UniProt Accession

K7KMA4; K7KMA4_SOYBN

Genbank Protein ID

KRH64789.1; KRH64790.1; KRH64791.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM000837; CM000837; CM000837

Gene Name

LOC100778853; GLYMA_04G255100

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA04G43440	GLYMA04G43440.2	GLYMA04G43440.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-36	123.1	50	86
UBD/Beta-Prp	5.50e-76	257.2	3	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H+++v++++f ++ +l+vsG+dD +ik+W+++ +++l
   Q: 50   HEGPVRGVHFhDSqPLFVSGGDDYKIKLWNYKLHRCL 86
           9*********8556****************8777665 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f++++++++++  +g i++wd+++g+l+ ++++he++v+ v f+++++++v+g++D+ ik+w+++   c+ +l gh d+v
   Q: 3    TKFETKSNRVKGLSFHKKRPWILASLHSGVIQLWDYRMGTLVDRFEEHEGPVRGVHFHDSQPLFVSGGDDYKIKLWNYKLHRCLFSLLGHLDYV 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.................ktgkllrt 174
           ++++f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp ++llvs+slD+t+r+Wd+                 + + + + 
   Q: 97   RTVQFHHESPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPRDDLLVSASLDQTLRVWDIsplrkkspssddmpfgsPDAVVKYV 189
           *********************************.************************************************998666666666 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           l+g h++ v++ sf++  + +vs+++d+++klw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++++ ++t+ +++++
   Q: 190  LEG-HDRGVNWASFHPALPLIVSAADDRQLKLWRMNDTKAweVDTLRGHMNNVSCVLFHAKQDIIVSNSEDKSIRVWDATKRTGIQTFRREHDR 282
           677.********************************777668**************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwklkknep 299
           ++  a+ +++ n l++g  ds   ++kl++++p
   Q: 283  FWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 313
           ******.6666655555.689999999988765 PP

Organism

Glycine max

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHKK RPWILASLHS GVIQLWDYRM GTLVDRFEEH EGPVRGVHFH 60
DSQPLFVSGG DDYKIKLWNY KLHRCLFSLL GHLDYVRTVQ FHHESPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTTTTTCT TTTACTTTTC TCTTCCTTTT TATACCAATT TACCTCGCTT CCCTTTTCAT 60
GCCTTTTTCT TGCTCCTCCG TACAACTTCA TGATCAACTG GTGAAAGAAC CCACATTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

gmx:100778853

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003385	Anas platyrhynchos	50.86	0.00e+00	1039.00
IUUC-Ate-010302	Aspergillus terreus	48.37	0.00e+00	1160.00
IUUC-Cin-025572	Ciona intestinalis	51.25	0.00e+00	1252.00
IUUC-Eeu-034874	Erinaceus europaeus	42.74	0.00e+00	668.00
IUUC-Gmo-039602	Gadus morhua	51.09	0.00e+00	1232.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	47.13	0.00e+00	775.00
IUUC-Nfi-068270	Neosartorya fischeri	48.13	0.00e+00	1122.00
IUUC-Opr-070952	Ochotona princeps	42.64	0.00e+00	670.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	38.65	0.00e+00	715.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.25	0.00e+00	934.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence