iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-13	48.6	348	366

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 15   llvsGsdDgtikvWDlrtg 33
            +++Gs D t+k+WD+r  
   Q: 348  EIATGSLDRTLKIWDTRNL 366
           49*************9865 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA in vitro (PubMed:22367945). May be involved in DNA-metabolic processes (PubMed:23349438).

Protein Sequence
(Fasta)

MPELTEFQKK RLENIKRNND LLKKLHLSGV ASQIKHEAGV LEKSRAPAKK KQKTTNTRAT 60
KSASPTLPTR RSRRLRGESA DDVKGIPNVN DNQLLKMGSP DGQDKNFIDA IKEKPVIGDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGAAT TAACAGAATT TCAGAAAAAA CGTTTAGAGA ACATCAAAAG GAATAACGAT 60
TTATTGAAAA AACTCCATTT GTCTGGAGTA GCATCTCAAA TTAAGCACGA GGCTGGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR033052--Cmr1/WDR76
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0034399--C:nuclear periphery
GO:0003677--F:DNA binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000001--P:regulation of DNA damage checkpoint

KEGG

sce:YDL156W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002605	Amborella trichopoda	24.68	8.00e-16	76.30
IUUC-Apl-003441	Anas platyrhynchos	22.73	8.00e-22	96.30
IUUC-Aca-004241	Anolis carolinensis	26.98	1.00e-26	112.00
IUUC-Aly-005444	Arabidopsis lyrata	25.23	3.00e-28	117.00
IUUC-Ath-007550	Arabidopsis thaliana	24.65	4.00e-27	114.00
IUUC-Ago-007715	Ashbya gossypii	56.48	3.00e-160	556.00
IUUC-Acl-008370	Aspergillus clavatus	31.68	8.00e-60	222.00
IUUC-Afl-008586	Aspergillus flavus	34.70	2.00e-55	208.00
IUUC-Afu-008907	Aspergillus fumigatus	31.78	5.00e-59	219.00
IUUC-Ani-009415	Aspergillus nidulans	34.78	2.00e-55	207.00
IUUC-Ang-009597	Aspergillus niger	27.31	1.00e-17	82.40
IUUC-Aor-010197	Aspergillus oryzae	34.70	1.00e-55	209.00
IUUC-Ate-010280	Aspergillus terreus	35.69	1.00e-57	215.00
IUUC-Bgr-012236	Blumeria graminis	33.70	2.00e-63	234.00
IUUC-Bta-013059	Bos taurus	24.06	2.00e-27	115.00
IUUC-Bci-013796	Botrytis cinerea	32.90	6.00e-63	233.00
IUUC-Bdi-015040	Brachypodium distachyon	25.75	6.00e-17	80.10
IUUC-Bol-015934	Brassica oleracea	24.62	5.00e-19	86.70
IUUC-Bra-018032	Brassica rapa	24.82	8.00e-21	93.20
IUUC-Cja-019043	Callithrix jacchus	24.53	1.00e-23	102.00
IUUC-Cfa-021103	Canis familiaris	25.38	2.00e-25	108.00
IUUC-Cpo-021508	Cavia porcellus	23.42	3.00e-24	104.00
IUUC-Cre-022967	Chlamydomonas reinhardtii	23.78	1.00e-08	53.10
IUUC-Csa-023555	Chlorocebus sabaeus	24.20	1.00e-22	99.00
IUUC-Cho-024931	Choloepus hoffmanni	24.76	4.00e-07	47.80
IUUC-Cin-025651	Ciona intestinalis	25.29	3.00e-25	107.00
IUUC-Cgl-026604	Colletotrichum gloeosporioides	36.69	3.00e-56	210.00
IUUC-Cne-027093	Cryptococcus neoformans	26.39	2.00e-32	131.00
IUUC-Cme-027238	Cyanidioschyzon merolae	21.47	2.00e-18	85.10
IUUC-Dre-027441	Danio rerio	25.38	2.00e-28	118.00
IUUC-Dno-029575	Dasypus novemcinctus	25.56	7.00e-28	116.00
IUUC-Dor-030554	Dipodomys ordii	26.79	5.00e-27	113.00
IUUC-Dse-031299	Dothistroma septosporum	35.33	2.00e-57	214.00
IUUC-Ete-032716	Echinops telfairi	26.16	4.00e-14	70.90
IUUC-Eca-034027	Equus caballus	23.73	4.00e-13	67.40
IUUC-Eeu-035234	Erinaceus europaeus	29.01	5.00e-13	67.40
IUUC-Fca-035892	Felis catus	28.28	9.00e-25	106.00
IUUC-Fal-036986	Ficedula albicollis	24.94	3.00e-18	84.30
IUUC-Fox-037750	Fusarium oxysporum	31.53	8.00e-63	232.00
IUUC-Fso-038198	Fusarium solani	30.85	5.00e-50	190.00
IUUC-Gmo-039683	Gadus morhua	21.24	1.00e-07	48.90
IUUC-Gga-040479	Gallus gallus	24.92	9.00e-16	75.90
IUUC-Gac-042043	Gasterosteus aculeatus	23.28	2.00e-24	104.00
IUUC-Gma-043913	Glycine max	24.28	1.00e-31	128.00
IUUC-Ggo-045290	Gorilla gorilla	24.58	5.00e-23	100.00
IUUC-Hsa-047021	Homo sapiens	24.58	1.00e-23	102.00
IUUC-Hvu-047193	Hordeum vulgare	30.03	6.00e-23	99.80
IUUC-Itr-047914	Ictidomys tridecemlineatus	24.44	2.00e-26	112.00
IUUC-Kpa-049275	Komagataella pastoris	33.51	5.00e-78	283.00
IUUC-Lch-049718	Latimeria chalumnae	23.64	8.00e-26	110.00
IUUC-Lpe-051708	Leersia perrieri	28.21	1.00e-17	82.40
IUUC-Loc-052565	Lepisosteus oculatus	24.53	9.00e-26	109.00
IUUC-Lma-053276	Leptosphaeria maculans	30.94	2.00e-59	222.00
IUUC-Laf-053970	Loxodonta africana	25.70	8.00e-30	123.00
IUUC-Mcc-054740	Macaca mulatta	23.87	4.00e-23	100.00
IUUC-Meu-056546	Macropus eugenii	23.44	2.00e-11	62.40
IUUC-Mtr-058451	Medicago truncatula	26.00	2.00e-35	141.00
IUUC-Mla-058906	Melampsora laricipopulina	27.81	3.00e-34	137.00
IUUC-Mga-059328	Meleagris gallopavo	26.57	2.00e-21	94.70
IUUC-Mvi-060555	Microbotryum violaceum	25.55	2.00e-28	118.00
IUUC-Mmr-061520	Microcebus murinus	26.03	2.00e-30	125.00
IUUC-Mdo-062812	Monodelphis domestica	25.48	3.00e-32	131.00
IUUC-Mmu-064011	Mus musculus	25.51	2.00e-20	91.70
IUUC-Mac-065376	Musa acuminata	25.70	9.00e-09	52.40
IUUC-Mpu-066486	Mustela putorius furo	25.62	4.00e-27	114.00
IUUC-Mlu-067721	Myotis lucifugus	24.42	1.00e-14	72.40
IUUC-Nfi-068314	Neosartorya fischeri	31.43	2.00e-59	221.00
IUUC-Ncr-068896	Neurospora crassa	30.15	9.00e-54	202.00
IUUC-Nle-069369	Nomascus leucogenys	24.00	3.00e-25	107.00
IUUC-Opr-070975	Ochotona princeps	26.54	2.00e-30	125.00
IUUC-Ont-072528	Oreochromis niloticus	24.33	7.00e-25	106.00
IUUC-Oan-072955	Ornithorhynchus anatinus	23.71	2.00e-24	105.00
IUUC-Ocu-074561	Oryctolagus cuniculus	25.67	9.00e-21	93.20
IUUC-Oba-074982	Oryza barthii	28.86	7.00e-24	103.00
IUUC-Obr-076551	Oryza brachyantha	28.45	5.00e-17	79.30
IUUC-Ogl-077685	Oryza glaberrima	28.81	5.00e-25	106.00
IUUC-Ogu-078331	Oryza glumaepatula	28.81	5.00e-25	106.00
IUUC-Oin-079507	Oryza indica	28.30	6.00e-24	103.00
IUUC-Olo-080604	Oryza longistaminata	29.58	8.00e-20	89.40
IUUC-Ome-081816	Oryza meridionalis	28.81	4.00e-24	103.00
IUUC-Oni-082051	Oryza nivara	28.81	4.00e-25	107.00
IUUC-Opu-083372	Oryza punctata	28.13	2.00e-23	101.00
IUUC-Oru-084578	Oryza rufipogon	28.81	5.00e-25	106.00
IUUC-Osa-086177	Oryza sativa	28.81	5.00e-25	106.00
IUUC-Ola-087208	Oryzias latipes	24.91	1.00e-22	98.60
IUUC-Olu-087680	Ostreococcus lucimarinus	23.56	3.00e-22	97.80
IUUC-Oga-088104	Otolemur garnettii	25.94	2.00e-25	108.00
IUUC-Oar-090157	Ovis aries	25.09	1.00e-28	119.00
IUUC-Ptr-091615	Pan troglodytes	24.39	5.00e-24	103.00
IUUC-Pan-092212	Papio anubis	24.20	5.00e-23	100.00
IUUC-Psi-092950	Pelodiscus sinensis	26.67	3.00e-25	107.00
IUUC-Pma-094625	Petromyzon marinus	26.06	2.00e-10	57.80
IUUC-Pno-094824	Phaeosphaeria nodorum	32.59	8.00e-66	242.00
IUUC-Pfo-096922	Poecilia formosa	25.58	6.00e-30	123.00
IUUC-Pab-097591	Pongo abelii	24.77	1.00e-24	106.00
IUUC-Pop-099337	Populus trichocarpa	26.12	1.00e-31	128.00
IUUC-Pca-101025	Procavia capensis	24.05	2.00e-24	105.00
IUUC-Ppe-101256	Prunus persica	24.20	7.00e-20	90.10
IUUC-Pva-102453	Pteropus vampyrus	26.47	1.00e-25	109.00
IUUC-Pgr-103436	Puccinia graminis	26.09	7.00e-38	149.00
IUUC-Ptt-103899	Puccinia triticina	32.17	2.00e-35	141.00
IUUC-Pte-104258	Pyrenophora teres	30.40	3.00e-57	214.00
IUUC-Pyt-104625	Pyrenophora triticirepentis	30.43	1.00e-57	215.00
IUUC-Rno-104843	Rattus norvegicus	22.43	3.00e-20	91.30
IUUC-Sha-106672	Sarcophilus harrisii	26.57	8.00e-36	142.00
IUUC-Smo-109660	Selaginella moellendorffii	27.27	4.00e-25	106.00
IUUC-Sit-109704	Setaria italica	29.44	1.00e-29	122.00
IUUC-Sly-111853	Solanum lycopersicum	23.36	5.00e-16	77.00
IUUC-Stu-112482	Solanum tuberosum	22.16	2.00e-12	65.10
IUUC-Sbi-114517	Sorghum bicolor	29.09	6.00e-20	90.10
IUUC-Sre-114960	Sporisorium reilianum	26.67	7.00e-18	83.60
IUUC-Ssc-115568	Sus scrofa	24.81	6.00e-26	110.00
IUUC-Tgu-117276	Taeniopygia guttata	22.59	1.00e-14	72.40
IUUC-Tru-117559	Takifugu rubripes	32.58	7.00e-11	57.00
IUUC-Tsy-119027	Tarsius syrichta	24.09	6.00e-09	53.10
IUUC-Tni-120358	Tetraodon nigroviridis	25.19	5.00e-32	130.00
IUUC-Tca-121273	Theobroma cacao	25.79	3.00e-21	94.40
IUUC-Tre-121932	Trichoderma reesei	37.54	3.00e-58	217.00
IUUC-Tvi-122567	Trichoderma virens	33.08	3.00e-64	237.00
IUUC-Tae-123506	Triticum aestivum	28.25	9.00e-22	95.90
IUUC-Tme-126958	Tuber melanosporum	35.94	3.00e-40	157.00
IUUC-Tbe-127425	Tupaia belangeri	27.25	3.00e-24	104.00
IUUC-Ttr-129123	Tursiops truncatus	26.86	7.00e-23	100.00
IUUC-Uma-129495	Ustilago maydis	23.31	4.00e-19	87.80
IUUC-Vda-129981	Verticillium dahliae	30.63	1.00e-61	228.00
IUUC-Vpa-130437	Vicugna pacos	26.47	2.00e-25	108.00
IUUC-Vvi-131430	Vitis vinifera	24.86	1.00e-19	88.60
IUUC-Xtr-132670	Xenopus tropicalis	24.86	7.00e-25	106.00
IUUC-Xma-133375	Xiphophorus maculatus	29.73	4.00e-28	117.00
IUUC-Yli-134341	Yarrowia lipolytica	34.32	2.00e-70	258.00
IUUC-Zma-135413	Zea mays	28.97	8.00e-29	119.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence