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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106379
UUCD1 version UUC-SaC-00138
Ensembl Protein ID YER107C
UniProt Accession P40066; D3DM14; GLE2_YEAST
Genbank Protein ID AAB64662.1; AAT92903.1; DAA07768.1
Protein Name Nucleoporin GLE2; Nuclear pore protein GLE2; poly(A) RNA export protein RAE1
Genbank Nucleotide ID U18839; AY692884; BK006939
Gene Name GLE2; RAE1; YER107C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YER107C YER107C YER107C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.90e-27 92.1 36 70
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           +ds++++af   +d +++++s+Dg++++WD+  gv
   Q: 36   EDSISDIAFspqQDFMFSASSWDGKVRIWDVQNGV 70
           589*******76557789999*********99887 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. It is specifically important for nuclear mRNA export.
 Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. It is specifically important for nuclear mRNA export.
Protein Sequence
(Fasta)
MSFFNRSNTT SALGTSTAMA NEKDLANDIV INSPAEDSIS DIAFSPQQDF MFSASSWDGK 60
VRIWDVQNGV PQGRAQHESS SPVLCTRWSN DGTKVASGGC DNALKLYDIA SGQTQQIGMH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106379|E3,WD_repeat|Saccharomyces cerevisiae
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Nucleotide Sequence
(Fasta)
ATGTCTTTTT TTAATCGATC AAATACAACC TCAGCTTTGG GAACGAGTAC TGCAATGGCG 60
AATGAAAAGG ATTTGGCCAA TGATATTGTC ATTAATAGCC CAGCAGAGGA CTCAATATCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106379|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0031965--C:nuclear membrane
GO:0005643--C:nuclear pore
GO:0031081--P:nuclear pore distribution
GO:0016973--P:poly(A)+ mRNA export from nucleus
GO:0000973--P:posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:2000728--P:regulation of mRNA export from nucleus in response to heat stress
GO:0000972--P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
KEGG sce:YER107C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000293 Aegilops tauschii 42.55 3.00e-77 279.00
IUUC-Aml-002179 Ailuropoda melanoleuca 42.20 1.00e-75 274.00
IUUC-Atr-002609 Amborella trichopoda 42.50 5.00e-81 292.00
IUUC-Apl-003637 Anas platyrhynchos 42.66 6.00e-79 285.00
IUUC-Aca-005042 Anolis carolinensis 43.35 7.00e-78 281.00
IUUC-Aly-006015 Arabidopsis lyrata 43.44 7.00e-81 291.00
IUUC-Ath-007659 Arabidopsis thaliana 42.25 2.00e-79 286.00
IUUC-Ago-008004 Ashbya gossypii 75.00 2.00e-165 572.00
IUUC-Acl-008030 Aspergillus clavatus 49.42 4.00e-102 362.00
IUUC-Afl-008636 Aspergillus flavus 50.29 6.00e-103 365.00
IUUC-Afu-009121 Aspergillus fumigatus 48.49 5.00e-102 362.00
IUUC-Ani-009238 Aspergillus nidulans 48.69 1.00e-101 360.00
IUUC-Ang-009801 Aspergillus niger 48.77 5.00e-102 362.00
IUUC-Aor-009974 Aspergillus oryzae 50.29 6.00e-103 365.00
IUUC-Ate-010406 Aspergillus terreus 48.54 5.00e-100 355.00
IUUC-Ame-011368 Astyanax mexicanus 42.20 2.00e-77 280.00
IUUC-Bgr-012233 Blumeria graminis 46.28 1.00e-93 334.00
IUUC-Bta-012856 Bos taurus 42.20 1.00e-75 274.00
IUUC-Bci-013964 Botrytis cinerea 48.70 3.00e-96 343.00
IUUC-Bdi-014049 Brachypodium distachyon 42.77 1.00e-80 291.00
IUUC-Bol-016601 Brassica oleracea 43.15 5.00e-79 285.00
IUUC-Bra-017292 Brassica rapa 43.73 7.00e-80 288.00
IUUC-Cel-018563 Caenorhabditis elegans 35.43 9.00e-63 231.00
IUUC-Cja-019700 Callithrix jacchus 42.20 6.00e-76 275.00
IUUC-Cfa-020337 Canis familiaris 42.20 1.00e-75 274.00
IUUC-Cpo-021858 Cavia porcellus 42.20 9.00e-76 275.00
IUUC-Cre-022748 Chlamydomonas reinhardtii 41.79 2.00e-78 283.00
IUUC-Csa-023322 Chlorocebus sabaeus 42.20 6.00e-76 275.00
IUUC-Cho-024930 Choloepus hoffmanni 34.02 4.00e-53 199.00
IUUC-Cin-025393 Ciona intestinalis 37.43 4.00e-71 259.00
IUUC-Csv-026093 Ciona savignyi 38.07 2.00e-71 260.00
IUUC-Cgl-026503 Colletotrichum gloeosporioides 42.34 5.00e-73 265.00
IUUC-Cne-026774 Cryptococcus neoformans 43.06 2.00e-78 283.00
IUUC-Cme-027243 Cyanidioschyzon merolae 37.21 9.00e-69 251.00
IUUC-Dre-028159 Danio rerio 43.06 4.00e-78 282.00
IUUC-Dno-028852 Dasypus novemcinctus 42.20 1.00e-75 274.00
IUUC-Dor-030318 Dipodomys ordii 34.62 2.00e-54 204.00
IUUC-Dse-031161 Dothistroma septosporum 49.00 5.00e-89 318.00
IUUC-Dme-032009 Drosophila melanogaster 44.54 1.00e-79 287.00
IUUC-Ete-032903 Echinops telfairi 32.14 5.00e-23 99.40
IUUC-Eca-033306 Equus caballus 41.91 5.00e-75 272.00
IUUC-Fca-035579 Felis catus 42.20 1.00e-75 274.00
IUUC-Fal-037582 Ficedula albicollis 42.94 2.00e-79 286.00
IUUC-Fox-037772 Fusarium oxysporum 49.86 4.00e-97 345.00
IUUC-Fso-038368 Fusarium solani 50.14 1.00e-100 357.00
IUUC-Gmo-038500 Gadus morhua 43.06 5.00e-77 279.00
IUUC-Ggr-040019 Gaeumannomyces graminis 48.57 4.00e-99 352.00
IUUC-Gga-040684 Gallus gallus 42.94 4.00e-79 286.00
IUUC-Gac-042592 Gasterosteus aculeatus 43.06 6.00e-78 282.00
IUUC-Gma-043208 Glycine max 43.57 4.00e-82 296.00
IUUC-Ggo-044965 Gorilla gorilla 42.20 1.00e-75 274.00
IUUC-Hsa-046779 Homo sapiens 43.17 7.00e-72 262.00
IUUC-Hvu-047380 Hordeum vulgare 44.09 3.00e-79 286.00
IUUC-Itr-048819 Ictidomys tridecemlineatus 42.20 1.00e-75 274.00
IUUC-Kpa-049284 Komagataella pastoris 56.01 2.00e-123 432.00
IUUC-Lch-050559 Latimeria chalumnae 39.13 1.00e-66 244.00
IUUC-Lpe-051050 Leersia perrieri 41.57 2.00e-82 297.00
IUUC-Loc-052874 Lepisosteus oculatus 43.35 7.00e-79 285.00
IUUC-Lma-053085 Leptosphaeria maculans 49.41 2.00e-94 337.00
IUUC-Laf-053980 Loxodonta africana 42.20 1.00e-75 274.00
IUUC-Mcc-055408 Macaca mulatta 42.20 6.00e-76 275.00
IUUC-Meu-056551 Macropus eugenii 39.31 3.00e-66 243.00
IUUC-Mor-057248 Magnaporthe oryzae 49.14 6.00e-100 355.00
IUUC-Mpo-057390 Magnaporthe poae 48.08 4.00e-98 349.00
IUUC-Mtr-058608 Medicago truncatula 43.15 8.00e-81 291.00
IUUC-Mla-059155 Melampsora laricipopulina 43.32 4.00e-87 312.00
IUUC-Mga-060140 Meleagris gallopavo 43.55 2.00e-72 263.00
IUUC-Mvi-060264 Microbotryum violaceum 49.54 2.00e-91 327.00
IUUC-Mmr-061533 Microcebus murinus 42.49 4.00e-76 276.00
IUUC-Mdo-062593 Monodelphis domestica 42.77 4.00e-77 279.00
IUUC-Mmu-063362 Mus musculus 42.20 1.00e-75 274.00
IUUC-Mac-064622 Musa acuminata 42.39 6.00e-78 282.00
IUUC-Mpu-065722 Mustela putorius furo 42.20 2.00e-75 274.00
IUUC-Mlu-068124 Myotis lucifugus 42.20 9.00e-76 275.00
IUUC-Nfi-068595 Neosartorya fischeri 50.00 6.00e-102 361.00
IUUC-Ncr-068790 Neurospora crassa 49.14 3.00e-99 353.00
IUUC-Nle-069273 Nomascus leucogenys 34.62 2.00e-54 203.00
IUUC-Opr-070320 Ochotona princeps 37.97 1.00e-65 241.00
IUUC-Ont-071303 Oreochromis niloticus 43.64 6.00e-79 285.00
IUUC-Oan-073724 Ornithorhynchus anatinus 43.06 5.00e-78 282.00
IUUC-Ocu-074961 Oryctolagus cuniculus 42.86 7.00e-72 262.00
IUUC-Oba-075879 Oryza barthii 41.92 3.00e-79 286.00
IUUC-Obr-076326 Oryza brachyantha 42.12 1.00e-80 291.00
IUUC-Ogl-077767 Oryza glaberrima 41.29 7.00e-82 295.00
IUUC-Ogu-078760 Oryza glumaepatula 41.30 3.00e-79 286.00
IUUC-Oin-080219 Oryza indica 41.29 7.00e-82 295.00
IUUC-Olo-081007 Oryza longistaminata 41.29 7.00e-82 295.00
IUUC-Ome-081848 Oryza meridionalis 38.89 2.00e-75 273.00
IUUC-Oni-082844 Oryza nivara 41.29 7.00e-82 295.00
IUUC-Opu-083511 Oryza punctata 39.83 3.00e-76 276.00
IUUC-Oru-085012 Oryza rufipogon 41.29 7.00e-82 295.00
IUUC-Osa-085287 Oryza sativa 41.29 7.00e-82 295.00
IUUC-Ola-087292 Oryzias latipes 43.93 2.00e-79 286.00
IUUC-Olu-087689 Ostreococcus lucimarinus 44.87 5.00e-88 315.00
IUUC-Oga-088821 Otolemur garnettii 42.20 1.00e-75 274.00
IUUC-Oar-090253 Ovis aries 42.20 1.00e-75 274.00
IUUC-Ptr-091097 Pan troglodytes 41.91 2.00e-75 273.00
IUUC-Pan-091835 Papio anubis 42.20 6.00e-76 275.00
IUUC-Psi-093000 Pelodiscus sinensis 43.64 6.00e-79 285.00
IUUC-Pma-094273 Petromyzon marinus 41.38 5.00e-78 282.00
IUUC-Pno-094920 Phaeosphaeria nodorum 46.48 5.00e-86 308.00
IUUC-Ppa-095202 Physcomitrella patens 47.64 3.00e-64 236.00
IUUC-Pfo-096388 Poecilia formosa 43.64 5.00e-79 285.00
IUUC-Pab-097533 Pongo abelii 42.20 6.00e-76 275.00
IUUC-Pop-099348 Populus trichocarpa 43.44 5.00e-76 275.00
IUUC-Pca-100326 Procavia capensis 34.41 4.00e-39 152.00
IUUC-Ppe-101817 Prunus persica 43.66 2.00e-82 297.00
IUUC-Pva-102233 Pteropus vampyrus 42.20 6.00e-76 275.00
IUUC-Pgr-103342 Puccinia graminis 44.94 8.00e-94 335.00
IUUC-Ptt-103836 Puccinia triticina 46.49 2.00e-94 337.00
IUUC-Pte-104387 Pyrenophora teres 49.11 5.00e-94 335.00
IUUC-Pyt-104737 Pyrenophora triticirepentis 45.65 5.00e-93 332.00
IUUC-Rno-105548 Rattus norvegicus 41.91 1.00e-75 274.00
IUUC-Sha-107617 Sarcophilus harrisii 43.60 2.00e-58 216.00
IUUC-Sja-107668 Schizosaccharomyces japonicus 52.73 7.00e-100 354.00
IUUC-Spo-108293 Schizosaccharomyces pombe 51.09 3.00e-105 372.00
IUUC-Ssl-108521 Sclerotinia sclerotiorum 28.15 3.00e-23 100.00
IUUC-Smo-109611 Selaginella moellendorffii 44.55 4.00e-85 305.00
IUUC-Sit-110436 Setaria italica 42.69 3.00e-79 286.00
IUUC-Sly-111037 Solanum lycopersicum 41.83 5.00e-86 308.00
IUUC-Stu-112371 Solanum tuberosum 38.20 5.00e-59 219.00
IUUC-Sar-113159 Sorex araneus 37.62 1.00e-15 74.70
IUUC-Sbi-113852 Sorghum bicolor 43.83 4.00e-80 289.00
IUUC-Sre-114922 Sporisorium reilianum 34.83 2.00e-62 230.00
IUUC-Ssc-116305 Sus scrofa 42.20 1.00e-75 274.00
IUUC-Tgu-116751 Taeniopygia guttata 42.94 2.00e-79 286.00
IUUC-Tru-117798 Takifugu rubripes 43.64 2.00e-79 286.00
IUUC-Tsy-119523 Tarsius syrichta 44.29 6.00e-68 248.00
IUUC-Tni-120477 Tetraodon nigroviridis 43.39 1.00e-78 284.00
IUUC-Tca-121802 Theobroma cacao 42.40 7.00e-80 288.00
IUUC-Tre-121994 Trichoderma reesei 49.86 4.00e-96 342.00
IUUC-Tvi-122631 Trichoderma virens 49.86 1.00e-95 341.00
IUUC-Tae-124794 Triticum aestivum 44.41 4.00e-80 289.00
IUUC-Tur-126390 Triticum urartu 41.59 1.00e-78 284.00
IUUC-Tme-127152 Tuber melanosporum 52.01 2.00e-104 370.00
IUUC-Tbe-127319 Tupaia belangeri 35.15 3.00e-37 147.00
IUUC-Ttr-129207 Tursiops truncatus 41.40 6.00e-74 268.00
IUUC-Uma-129342 Ustilago maydis 34.73 1.00e-52 198.00
IUUC-Vda-129865 Verticillium dahliae 48.14 1.00e-96 344.00
IUUC-Vpa-130076 Vicugna pacos 37.70 6.00e-55 205.00
IUUC-Vvi-131104 Vitis vinifera 43.60 5.00e-82 295.00
IUUC-Xtr-132917 Xenopus tropicalis 35.14 4.00e-50 189.00
IUUC-Xma-133615 Xiphophorus maculatus 43.35 9.00e-79 285.00
IUUC-Yli-134431 Yarrowia lipolytica 54.08 3.00e-116 409.00
IUUC-Zma-135142 Zea mays 42.90 2.00e-78 283.00
Created Date 25-Jun-2017

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