iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009135

Ensembl Protein ID

CADANIAP00007048

UniProt Accession

C8V3C4; C8V3C4_EMENI

Genbank Protein ID

CBF70445.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

BN001301

Gene Name

ANIA_05972

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00007048	CADANIAT00007048	CADANIAP00007048

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-31	104.6	96	129
UBD/Beta-Prp	9.30e-66	221.1	13	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H d ++++a  ++ ++++++sdD tik+WD+ +g
   Q: 96   HPDYIRSIAVhPTqPFVLTASDDMTIKLWDWEKG 129
           99********9888****************8765 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           +++++ ++f+p +++++t+ ++g + +w+++t++ +++++  + +v+a +f+ +++++v gs+D  +++++++t++ + ++++h d+++s+++
   Q: 13   SERVKGIDFHPTEPWILTTLYSGHVYIWSYETQSIIKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRIYNYNTSEKIASFEAHPDYIRSIAV 105
           678999*************************************************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.. 192
           +p++ +++++s+d ti++wd+e+g++  ++ +gh++ v++++++p++ n ++s++lDrtv++W+l +     tl+   t+ v+++++ ++   
   Q: 106  HPTQPFVLTASDDMTIKLWDWEKGWKCVQVYEGHSHYVMGLAINPKDtNTFASACLDRTVKIWSLGSPHANFTLEAHETKGVNHVDYYPQAdk 198
           ************************98888***********************************************99********8887777 PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           ++l++ s+d+tvk+wd+ t+  + tl+ght+nv+    +p+   ++sgs+Dg+i+iW   +  l ++l++  ++ ++v++ + g++ ++lg +
   Q: 199  PYLLTTSDDKTVKVWDYTTKALIATLEGHTSNVSFACYHPELPVIISGSEDGTIKIWHANTYRLEQSLSYGLERAWCVSY-QRGKQGVALGFD 290
           *******************************************************************************9.666666666655 PP
   S: 286  dskvni 291
           d+ v +
   Q: 291  DGAVVV 296
           555544 PP

Organism

Aspergillus nidulans

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDIKRQLF ARSERVKGID FHPTEPWILT TLYSGHVYIW SYETQSIIKT FELTDVPVRA 60
GRFIARKNWI VCGSDDFQLR IYNYNTSEKI ASFEAHPDYI RSIAVHPTQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCGTCGA CGTTCTACAA GGCTTCTCCC CTCGGCTGCT CTCTCTTGTG CTTATATTTC 60
GCCGTCGAAC TATACTTTTG CCGAAAGTTT TCTGCAATTC CGGGCTGGGC TGTTAGAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	46.36	0.00e+00	780.00
IUUC-Aml-002154	Ailuropoda melanoleuca	54.21	0.00e+00	964.00
IUUC-Atr-003090	Amborella trichopoda	56.00	0.00e+00	901.00
IUUC-Apl-003976	Anas platyrhynchos	55.95	0.00e+00	962.00
IUUC-Aca-004301	Anolis carolinensis	53.06	0.00e+00	967.00
IUUC-Aly-005643	Arabidopsis lyrata	52.93	0.00e+00	889.00
IUUC-Ath-007630	Arabidopsis thaliana	53.39	0.00e+00	910.00
IUUC-Ago-007914	Ashbya gossypii	49.51	0.00e+00	834.00
IUUC-Acl-008237	Aspergillus clavatus	89.82	0.00e+00	1587.00
IUUC-Afl-008535	Aspergillus flavus	90.23	0.00e+00	1531.00
IUUC-Afu-008845	Aspergillus fumigatus	90.41	0.00e+00	1571.00
IUUC-Ang-009654	Aspergillus niger	94.51	0.00e+00	1321.00
IUUC-Aor-009939	Aspergillus oryzae	90.39	0.00e+00	1625.00
IUUC-Ate-010355	Aspergillus terreus	92.30	0.00e+00	1548.00
IUUC-Ame-010922	Astyanax mexicanus	51.92	0.00e+00	838.00
IUUC-Bgr-012249	Blumeria graminis	78.05	0.00e+00	1336.00
IUUC-Bta-013579	Bos taurus	55.93	0.00e+00	881.00
IUUC-Bci-013866	Botrytis cinerea	79.39	0.00e+00	1361.00
IUUC-Bdi-015046	Brachypodium distachyon	53.11	0.00e+00	914.00
IUUC-Bol-015466	Brassica oleracea	52.55	0.00e+00	885.00
IUUC-Bra-016617	Brassica rapa	52.24	0.00e+00	880.00
IUUC-Cel-018387	Caenorhabditis elegans	50.85	0.00e+00	888.00
IUUC-Cja-019145	Callithrix jacchus	54.33	0.00e+00	965.00
IUUC-Cfa-020564	Canis familiaris	52.55	0.00e+00	964.00
IUUC-Cpo-022201	Cavia porcellus	52.00	0.00e+00	966.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	53.72	0.00e+00	863.00
IUUC-Csa-023383	Chlorocebus sabaeus	58.70	0.00e+00	752.00
IUUC-Cho-024454	Choloepus hoffmanni	52.71	0.00e+00	836.00
IUUC-Cin-025681	Ciona intestinalis	52.95	0.00e+00	894.00
IUUC-Csv-026012	Ciona savignyi	53.15	0.00e+00	903.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	74.08	0.00e+00	1212.00
IUUC-Cne-026986	Cryptococcus neoformans	57.18	0.00e+00	975.00
IUUC-Cme-027219	Cyanidioschyzon merolae	46.77	0.00e+00	792.00
IUUC-Dre-027846	Danio rerio	53.88	0.00e+00	967.00
IUUC-Dor-030462	Dipodomys ordii	53.75	0.00e+00	779.00
IUUC-Dse-031268	Dothistroma septosporum	78.64	0.00e+00	1360.00
IUUC-Dme-031791	Drosophila melanogaster	53.17	0.00e+00	916.00
IUUC-Ete-033166	Echinops telfairi	52.32	0.00e+00	627.00
IUUC-Eca-034180	Equus caballus	50.98	0.00e+00	923.00
IUUC-Eeu-035086	Erinaceus europaeus	42.86	2.00e-99	355.00
IUUC-Fca-036265	Felis catus	54.21	0.00e+00	963.00
IUUC-Fal-037202	Ficedula albicollis	52.97	0.00e+00	916.00
IUUC-Fox-037711	Fusarium oxysporum	79.08	0.00e+00	1265.00
IUUC-Fso-038268	Fusarium solani	77.98	0.00e+00	1258.00
IUUC-Gmo-039046	Gadus morhua	55.57	0.00e+00	956.00
IUUC-Ggr-039863	Gaeumannomyces graminis	80.68	0.00e+00	1326.00
IUUC-Gga-041112	Gallus gallus	54.33	0.00e+00	965.00
IUUC-Gac-041733	Gasterosteus aculeatus	53.60	0.00e+00	935.00
IUUC-Gma-044333	Glycine max	52.94	0.00e+00	922.00
IUUC-Ggo-044984	Gorilla gorilla	52.43	0.00e+00	967.00
IUUC-Hsa-046698	Homo sapiens	52.31	0.00e+00	966.00
IUUC-Hvu-047669	Hordeum vulgare	60.73	1.00e-142	497.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	54.21	0.00e+00	962.00
IUUC-Kpa-049265	Komagataella pastoris	56.97	0.00e+00	980.00
IUUC-Lch-050473	Latimeria chalumnae	55.44	0.00e+00	958.00
IUUC-Lpe-051579	Leersia perrieri	52.39	0.00e+00	904.00
IUUC-Loc-052675	Lepisosteus oculatus	53.05	0.00e+00	960.00
IUUC-Lma-053218	Leptosphaeria maculans	74.70	0.00e+00	1262.00
IUUC-Laf-053757	Loxodonta africana	53.96	0.00e+00	956.00
IUUC-Mcc-054859	Macaca mulatta	54.33	0.00e+00	965.00
IUUC-Meu-056174	Macropus eugenii	42.70	4.00e-86	311.00
IUUC-Mor-057264	Magnaporthe oryzae	79.57	0.00e+00	1301.00
IUUC-Mpo-057538	Magnaporthe poae	80.68	0.00e+00	1347.00
IUUC-Mtr-058310	Medicago truncatula	52.61	0.00e+00	920.00
IUUC-Mla-058937	Melampsora laricipopulina	55.62	0.00e+00	969.00
IUUC-Mga-059875	Meleagris gallopavo	52.80	0.00e+00	961.00
IUUC-Mvi-060240	Microbotryum violaceum	54.99	0.00e+00	989.00
IUUC-Mmr-061261	Microcebus murinus	54.21	0.00e+00	964.00
IUUC-Mdo-062076	Monodelphis domestica	52.86	0.00e+00	967.00
IUUC-Mmu-063324	Mus musculus	54.58	0.00e+00	969.00
IUUC-Mac-064636	Musa acuminata	54.79	0.00e+00	905.00
IUUC-Mpu-065961	Mustela putorius furo	54.21	0.00e+00	963.00
IUUC-Mlu-067059	Myotis lucifugus	51.73	0.00e+00	933.00
IUUC-Nfi-068277	Neosartorya fischeri	90.49	0.00e+00	1560.00
IUUC-Ncr-068659	Neurospora crassa	75.69	0.00e+00	1323.00
IUUC-Nle-069034	Nomascus leucogenys	54.33	0.00e+00	965.00
IUUC-Opr-070334	Ochotona princeps	56.91	0.00e+00	912.00
IUUC-Ont-071563	Oreochromis niloticus	54.21	0.00e+00	963.00
IUUC-Oan-073416	Ornithorhynchus anatinus	55.85	0.00e+00	921.00
IUUC-Ocu-074522	Oryctolagus cuniculus	55.83	0.00e+00	960.00
IUUC-Oba-075760	Oryza barthii	52.32	0.00e+00	899.00
IUUC-Obr-076201	Oryza brachyantha	53.10	0.00e+00	908.00
IUUC-Ogl-077450	Oryza glaberrima	52.93	0.00e+00	922.00
IUUC-Ogu-078994	Oryza glumaepatula	52.32	0.00e+00	897.00
IUUC-Oin-079856	Oryza indica	49.72	0.00e+00	894.00
IUUC-Olo-080731	Oryza longistaminata	52.71	0.00e+00	884.00
IUUC-Ome-081554	Oryza meridionalis	46.46	0.00e+00	827.00
IUUC-Oni-082324	Oryza nivara	52.32	0.00e+00	899.00
IUUC-Opu-083400	Oryza punctata	50.00	0.00e+00	875.00
IUUC-Oru-084829	Oryza rufipogon	52.32	0.00e+00	899.00
IUUC-Osa-086026	Oryza sativa	53.17	0.00e+00	927.00
IUUC-Ola-087245	Oryzias latipes	55.95	0.00e+00	959.00
IUUC-Olu-087655	Ostreococcus lucimarinus	54.01	0.00e+00	912.00
IUUC-Oga-088163	Otolemur garnettii	52.50	0.00e+00	918.00
IUUC-Oar-089842	Ovis aries	51.77	0.00e+00	965.00
IUUC-Ptr-090501	Pan troglodytes	54.33	0.00e+00	965.00
IUUC-Pan-092011	Papio anubis	52.78	0.00e+00	967.00
IUUC-Psi-093308	Pelodiscus sinensis	53.40	0.00e+00	965.00
IUUC-Pma-094695	Petromyzon marinus	54.25	0.00e+00	897.00
IUUC-Pno-094785	Phaeosphaeria nodorum	78.89	3.00e-139	487.00
IUUC-Ppa-095638	Physcomitrella patens	53.63	0.00e+00	926.00
IUUC-Pfo-096587	Poecilia formosa	56.23	0.00e+00	962.00
IUUC-Pab-097926	Pongo abelii	51.21	0.00e+00	890.00
IUUC-Pop-099634	Populus trichocarpa	53.45	0.00e+00	924.00
IUUC-Pca-100965	Procavia capensis	53.11	0.00e+00	928.00
IUUC-Ppe-101470	Prunus persica	53.72	0.00e+00	924.00
IUUC-Pva-102451	Pteropus vampyrus	52.85	0.00e+00	765.00
IUUC-Pgr-103590	Puccinia graminis	58.44	0.00e+00	1013.00
IUUC-Ptt-103868	Puccinia triticina	57.72	0.00e+00	1006.00
IUUC-Pte-104274	Pyrenophora teres	76.41	0.00e+00	1298.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	71.98	0.00e+00	1227.00
IUUC-Rno-105979	Rattus norvegicus	48.70	0.00e+00	736.00
IUUC-Sce-106269	Saccharomyces cerevisiae	48.79	0.00e+00	880.00
IUUC-Sha-106905	Sarcophilus harrisii	54.46	0.00e+00	968.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	53.92	0.00e+00	902.00
IUUC-Spo-108299	Schizosaccharomyces pombe	53.47	0.00e+00	921.00
IUUC-Smo-108695	Selaginella moellendorffii	51.95	0.00e+00	909.00
IUUC-Sit-110239	Setaria italica	53.05	0.00e+00	924.00
IUUC-Sly-111775	Solanum lycopersicum	54.12	0.00e+00	925.00
IUUC-Stu-112906	Solanum tuberosum	53.00	0.00e+00	832.00
IUUC-Sar-113472	Sorex araneus	52.01	0.00e+00	697.00
IUUC-Sbi-113886	Sorghum bicolor	53.36	0.00e+00	922.00
IUUC-Sre-115040	Sporisorium reilianum	57.07	0.00e+00	990.00
IUUC-Ssc-115593	Sus scrofa	54.09	0.00e+00	962.00
IUUC-Tgu-117239	Taeniopygia guttata	53.65	0.00e+00	962.00
IUUC-Tru-118025	Takifugu rubripes	53.07	0.00e+00	956.00
IUUC-Tsy-118824	Tarsius syrichta	51.90	0.00e+00	708.00
IUUC-Tni-120142	Tetraodon nigroviridis	53.48	0.00e+00	954.00
IUUC-Tca-121613	Theobroma cacao	53.71	0.00e+00	926.00
IUUC-Tre-122072	Trichoderma reesei	77.80	0.00e+00	1314.00
IUUC-Tvi-122546	Trichoderma virens	77.97	0.00e+00	1316.00
IUUC-Tae-125292	Triticum aestivum	53.17	0.00e+00	920.00
IUUC-Tur-126283	Triticum urartu	46.72	0.00e+00	779.00
IUUC-Tme-127041	Tuber melanosporum	75.30	0.00e+00	1333.00
IUUC-Tbe-127770	Tupaia belangeri	54.20	0.00e+00	797.00
IUUC-Ttr-129294	Tursiops truncatus	52.20	0.00e+00	961.00
IUUC-Uma-129351	Ustilago maydis	56.21	0.00e+00	990.00
IUUC-Vda-129716	Verticillium dahliae	77.87	0.00e+00	1378.00
IUUC-Vpa-130037	Vicugna pacos	44.66	6.00e-109	386.00
IUUC-Vvi-131689	Vitis vinifera	53.96	0.00e+00	923.00
IUUC-Xtr-132633	Xenopus tropicalis	56.48	0.00e+00	970.00
IUUC-Xma-133347	Xiphophorus maculatus	56.10	0.00e+00	962.00
IUUC-Yli-134455	Yarrowia lipolytica	59.50	0.00e+00	980.00
IUUC-Zma-135867	Zea mays	53.60	0.00e+00	938.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence