iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Smo-108803

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-protein ligase, PUB59

Genbank Nucleotide ID

GL377573

Gene Name

PUB59-2; SELMODRAFT_168695

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_168695	EFJ31494	EFJ31494

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-25	87.5	259	289
E3 activity/RING/U-box	1.00e-14	55.0	2	66
UBD/Beta-Prp	5.40e-47	161.1	224	461

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH+ +vt+++f   d+l++++s D+t+k+W 
   Q: 259  GHSKKVTSVKFvaRDDLVLTASADKTVKIWQ 289
           8************99***************5 PP

E3 activity/RING/U-box

   S: 7    lCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
            C+Is+  +++Pv+++ sG  ++r+ Iek+la++g+ cPvt+++lteedl P +t +++  + + +
   Q: 2    FCAISGLTPEEPVISKrSGLLFERRLIEKHLAENGT-CPVTGESLTEEDLLPVKTNKAVKPRPVTA 66
           6**********************************9.********************999887665 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw...dlstgkcvhtlkghedsvlslsfspsgdklvsG 112
           +++++ +k++++tg+ dg  +v+d ++g  ++sl gh+++vt+vkf  ++++ +t+s D+t+k+w   +  +++c +tlk+h++++++++++p++ ++v++
   Q: 224  SIDIHHQKDVILTGGNDGNAIVFDRSSGEIVASLVGHSKKVTSVKFVARDDLVLTASADKTVKIWqggEEGAYSCKQTLKEHSAEIRAITVHPTNRFFVTA 324
           47889999999999999999999999999999999999999999999999999999999999999766666999999999999999999999999999999 PP
   S: 113  shdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           s+d+t   +dl++g+c  + t++  ++  + +++hpdg +l +G++ + vr+Wd+   ++ + + +++g h ++v+ lsf++ng +l++++ dg vk+wdl
   Q: 325  SDDKTWAFYDLNSGTCTTQvTDAAVQDGYTAASFHPDGLILGTGTAESLVRIWDVksqASSNNVAKFEG-HSGPVTELSFSENGYFLATAASDG-VKVWDL 423
           999999999999999999889999999999999999999999999999999999977777788889998.999999999999999999999998.899999 PP
   S: 210  qtgecvrtlnght..dnvksvrfspnderlvsgssDgs 245
           ++ +  r++  ++  ++++ v+f+  + +l+ ++sD  
   Q: 424  RKLKNFRSFSPYDpsTPTSTVQFDHSGSYLALAGSDIR 461
           98888888876544499999999999999999998855 PP

Organism

Selaginella moellendorffii

Protein Sequence
(Fasta)

MFCAISGLTP EEPVISKRSG LLFERRLIEK HLAENGTCPV TGESLTEEDL LPVKTNKAVK 60
PRPVTATSIP GMLGMFQNEW DAVVLSNYHL EQQLNNARQE LSHALYQHDA ACRVIARLKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCGGGAG CGGCTCGGCT CGTCACGATG TTCTGCGCCA GTGAGTGAAT GCTCCTTCTC 60
TAGCTCCAGC CGTCGTTACG AGCTCGTATT GTGTGTTTTT CTCGCAGTCT CTGGATTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

smo:SELMODRAFT_168695

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bci-013901	Botrytis cinerea	34.36	1.00e-72	266.00
IUUC-Nfi-068504	Neosartorya fischeri	35.98	4.00e-74	271.00
IUUC-Sce-106147	Saccharomyces cerevisiae	24.21	5.00e-21	95.10
IUUC-Ssl-108628	Sclerotinia sclerotiorum	32.82	5.00e-67	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence