iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	24155900

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	4.20e-06	25.6	1239	1277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl + + g +   CgH f+++C+  w       + + +CP+C+
   Q: 1239 CSICLGEVEIGAI-IKCGHYFCKSCILTW------LRAHSKCPICK 1277
           ********99555.99*************......**********6 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

By heat shock and UV radiation.

Protein Sequence
(Fasta)

MSAVGALLAR EYNVTAEKCD FFLENGSFDS VIAALPALNQ EQETVTQKVS KNGKELINVA 60
SVNIEIPERI SLSNNGRQLF KFIVDIEILP CENDNEATLV VSSDSVSLFQ IGFKMENNSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGCAG TAGGTGCGCT ATTAGCAAGG GAGTACAACG TGACTGCCGA AAAATGCGAC 60
TTTTTCCTAG AAAATGGTTC TTTTGATTCA GTGATAGCAG CATTGCCAGC GCTAAATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0346--Stress response
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004386--F:helicase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0045003--P:double-strand break repair via synthesis-dependent strand annealing

KEGG

sce:YLR247C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007786	Ashbya gossypii	38.78	0.00e+00	923.00
IUUC-Acl-008380	Aspergillus clavatus	24.82	2.00e-83	302.00
IUUC-Afu-008890	Aspergillus fumigatus	26.87	6.00e-98	350.00
IUUC-Ani-009351	Aspergillus nidulans	26.19	5.00e-93	334.00
IUUC-Ang-009583	Aspergillus niger	25.54	2.00e-89	322.00
IUUC-Aor-009893	Aspergillus oryzae	25.15	2.00e-47	182.00
IUUC-Ate-010385	Aspergillus terreus	26.04	7.00e-86	310.00
IUUC-Bgr-012295	Blumeria graminis	25.52	1.00e-76	280.00
IUUC-Bci-013701	Botrytis cinerea	26.25	2.00e-88	319.00
IUUC-Cho-024617	Choloepus hoffmanni	35.66	1.00e-18	87.40
IUUC-Cgl-026624	Colletotrichum gloeosporioides	25.92	2.00e-93	335.00
IUUC-Cne-027060	Cryptococcus neoformans	24.84	5.00e-24	105.00
IUUC-Dse-031372	Dothistroma septosporum	23.74	7.00e-88	317.00
IUUC-Dme-031785	Drosophila melanogaster	28.72	7.00e-20	91.30
IUUC-Fox-038048	Fusarium oxysporum	25.08	6.00e-42	164.00
IUUC-Fso-038224	Fusarium solani	25.66	3.00e-83	301.00
IUUC-Ggr-040102	Gaeumannomyces graminis	24.70	6.00e-81	294.00
IUUC-Kpa-049196	Komagataella pastoris	26.90	5.00e-109	387.00
IUUC-Lma-053266	Leptosphaeria maculans	23.85	3.00e-56	211.00
IUUC-Meu-056104	Macropus eugenii	46.75	1.00e-15	77.80
IUUC-Mor-057226	Magnaporthe oryzae	23.01	2.00e-41	162.00
IUUC-Mpo-057528	Magnaporthe poae	26.38	2.00e-44	173.00
IUUC-Mvi-060213	Microbotryum violaceum	23.73	6.00e-67	248.00
IUUC-Nfi-068264	Neosartorya fischeri	26.58	1.00e-97	349.00
IUUC-Ncr-068745	Neurospora crassa	24.78	6.00e-85	307.00
IUUC-Pno-095005	Phaeosphaeria nodorum	25.44	1.00e-39	157.00
IUUC-Pte-104081	Pyrenophora teres	31.64	6.00e-38	151.00
IUUC-Pyt-104477	Pyrenophora triticirepentis	29.52	1.00e-39	157.00
IUUC-Sja-107755	Schizosaccharomyces japonicus	22.70	5.00e-32	131.00
IUUC-Spo-108132	Schizosaccharomyces pombe	23.61	9.00e-63	233.00
IUUC-Ssl-108615	Sclerotinia sclerotiorum	22.70	7.00e-33	134.00
IUUC-Sre-115189	Sporisorium reilianum	26.16	7.00e-40	158.00
IUUC-Tre-122005	Trichoderma reesei	25.63	1.00e-83	303.00
IUUC-Tvi-122328	Trichoderma virens	24.93	3.00e-82	298.00
IUUC-Uma-129442	Ustilago maydis	25.13	4.00e-36	145.00
IUUC-Vda-129795	Verticillium dahliae	23.81	1.00e-74	273.00
IUUC-Yli-134508	Yarrowia lipolytica	25.86	7.00e-44	171.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence