iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-16	56.7	583	620
UBD/Beta-Prp	3.30e-44	149.7	543	644

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++++t+++f ++ + +vs+s D ti+ WDl tg ++
   Q: 583  GHSNRITAFDFsPEgRWIVSASLDSTIRTWDLPTGGCI 620
           8***********99999******************996 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklv 110
           +++it++ ++++++l+a + +d +i v d+ t+ ++r+l gh++ +ta +fsp+g ++v++s D ti+ wdl tg c+  +   ++ ++ ++fsp+gd l+
   Q: 543  DAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDSTIRTWDLPTGGCIDGII-VDNVATNVKFSPNGDLLA 642
           6799*****************************************************************************9.9999999******99998 PP
   S: 111  sG 112
           ++
   Q: 643  TT 644
           75 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

Protein Sequence
(Fasta)

MSIDLKKRKV EEDVRSRGKN SKIFSPFRII GNVSNGVPFA TGTLGSTFYI VTCVGKTFQI 60
YDANTLHLLF VSEKETPSSI VALSAHFHYV YAAYENKVGI YKRGIEEHLL ELETDANVEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTATCG ACTTGAAAAA AAGAAAAGTC GAAGAAGACG TAAGAAGTAG AGGGAAAAAT 60
TCTAAGATAT TTTCCCCTTT CCGGATTATT GGTAATGTTA GCAATGGTGT TCCTTTTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0042274--P:ribosomal small subunit biogenesis
GO:0031167--P:rRNA methylation
GO:0006364--P:rRNA processing

KEGG

sce:YLR409C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	29.99	1.00e-110	392.00
IUUC-Aml-002289	Ailuropoda melanoleuca	31.66	1.00e-120	425.00
IUUC-Atr-002859	Amborella trichopoda	28.98	3.00e-88	317.00
IUUC-Apl-003505	Anas platyrhynchos	29.64	8.00e-98	349.00
IUUC-Aca-004339	Anolis carolinensis	29.39	2.00e-109	388.00
IUUC-Aly-005913	Arabidopsis lyrata	30.13	3.00e-111	394.00
IUUC-Ath-006767	Arabidopsis thaliana	30.85	2.00e-113	401.00
IUUC-Ago-007763	Ashbya gossypii	64.29	0.00e+00	1258.00
IUUC-Acl-008275	Aspergillus clavatus	36.42	5.00e-115	406.00
IUUC-Afl-008457	Aspergillus flavus	37.26	5.00e-121	426.00
IUUC-Afu-008914	Aspergillus fumigatus	36.76	1.00e-122	431.00
IUUC-Ani-009225	Aspergillus nidulans	34.82	1.00e-133	468.00
IUUC-Aor-010046	Aspergillus oryzae	34.43	5.00e-151	526.00
IUUC-Ate-010337	Aspergillus terreus	34.50	3.00e-145	507.00
IUUC-Ame-010963	Astyanax mexicanus	30.10	3.00e-106	377.00
IUUC-Bgr-011973	Blumeria graminis	35.12	2.00e-151	527.00
IUUC-Bta-012462	Bos taurus	31.95	2.00e-118	418.00
IUUC-Bci-013940	Botrytis cinerea	34.40	6.00e-158	549.00
IUUC-Bdi-014725	Brachypodium distachyon	29.78	1.00e-109	388.00
IUUC-Bol-016534	Brassica oleracea	30.16	6.00e-108	383.00
IUUC-Bra-016781	Brassica rapa	29.88	1.00e-103	369.00
IUUC-Cel-018581	Caenorhabditis elegans	26.44	3.00e-59	221.00
IUUC-Cja-019675	Callithrix jacchus	31.72	1.00e-128	451.00
IUUC-Cfa-020118	Canis familiaris	31.21	3.00e-117	414.00
IUUC-Cpo-021798	Cavia porcellus	31.90	4.00e-122	430.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	29.82	1.00e-28	119.00
IUUC-Csa-023547	Chlorocebus sabaeus	31.76	2.00e-118	417.00
IUUC-Cho-024518	Choloepus hoffmanni	32.48	4.00e-55	207.00
IUUC-Cin-025339	Ciona intestinalis	29.44	1.00e-111	395.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	34.41	2.00e-144	504.00
IUUC-Cne-026859	Cryptococcus neoformans	34.18	2.00e-137	481.00
IUUC-Cme-027173	Cyanidioschyzon merolae	26.17	2.00e-60	225.00
IUUC-Dre-027733	Danio rerio	30.84	9.00e-109	385.00
IUUC-Dno-029439	Dasypus novemcinctus	32.27	1.00e-120	425.00
IUUC-Dor-030329	Dipodomys ordii	33.87	2.00e-62	231.00
IUUC-Dse-031511	Dothistroma septosporum	33.04	6.00e-127	446.00
IUUC-Dme-031694	Drosophila melanogaster	29.23	3.00e-99	354.00
IUUC-Ete-032930	Echinops telfairi	32.27	1.00e-107	382.00
IUUC-Eca-033302	Equus caballus	32.44	5.00e-120	423.00
IUUC-Eeu-034516	Erinaceus europaeus	31.54	2.00e-126	444.00
IUUC-Fca-036064	Felis catus	31.78	2.00e-120	424.00
IUUC-Fal-037024	Ficedula albicollis	29.30	5.00e-110	390.00
IUUC-Fox-037787	Fusarium oxysporum	34.19	8.00e-135	472.00
IUUC-Fso-038378	Fusarium solani	34.00	7.00e-139	486.00
IUUC-Gmo-039637	Gadus morhua	30.97	6.00e-69	253.00
IUUC-Ggr-040108	Gaeumannomyces graminis	33.24	3.00e-140	491.00
IUUC-Gga-040982	Gallus gallus	29.74	6.00e-118	416.00
IUUC-Gac-041565	Gasterosteus aculeatus	30.47	6.00e-103	366.00
IUUC-Gma-043414	Glycine max	30.99	3.00e-115	407.00
IUUC-Ggo-045463	Gorilla gorilla	31.87	4.00e-121	427.00
IUUC-Hsa-045675	Homo sapiens	31.83	3.00e-122	430.00
IUUC-Hvu-047352	Hordeum vulgare	29.36	2.00e-101	361.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	31.78	1.00e-128	451.00
IUUC-Kpa-049164	Komagataella pastoris	56.32	0.00e+00	1021.00
IUUC-Lch-050476	Latimeria chalumnae	30.27	6.00e-117	413.00
IUUC-Lpe-051556	Leersia perrieri	27.98	9.00e-73	266.00
IUUC-Loc-052820	Lepisosteus oculatus	29.58	6.00e-112	396.00
IUUC-Lma-052961	Leptosphaeria maculans	33.87	7.00e-130	456.00
IUUC-Laf-054006	Loxodonta africana	32.55	2.00e-115	407.00
IUUC-Mcc-055037	Macaca mulatta	31.72	4.00e-121	427.00
IUUC-Mor-057280	Magnaporthe oryzae	34.52	5.00e-148	516.00
IUUC-Mpo-057408	Magnaporthe poae	33.02	4.00e-132	464.00
IUUC-Mtr-058473	Medicago truncatula	32.13	3.00e-120	424.00
IUUC-Mla-058892	Melampsora laricipopulina	31.11	2.00e-97	348.00
IUUC-Mga-059598	Meleagris gallopavo	27.04	5.00e-84	303.00
IUUC-Mvi-060334	Microbotryum violaceum	32.50	2.00e-110	392.00
IUUC-Mmr-061239	Microcebus murinus	31.61	1.00e-117	415.00
IUUC-Mdo-062471	Monodelphis domestica	30.89	4.00e-111	393.00
IUUC-Mmu-063872	Mus musculus	31.67	4.00e-124	436.00
IUUC-Mac-064631	Musa acuminata	29.10	3.00e-87	314.00
IUUC-Mpu-066039	Mustela putorius furo	31.63	5.00e-128	449.00
IUUC-Mlu-067485	Myotis lucifugus	32.25	3.00e-119	420.00
IUUC-Nfi-068319	Neosartorya fischeri	33.68	2.00e-134	471.00
IUUC-Ncr-068725	Neurospora crassa	33.65	1.00e-134	472.00
IUUC-Nle-069050	Nomascus leucogenys	32.06	3.00e-123	434.00
IUUC-Opr-070437	Ochotona princeps	30.04	8.00e-27	113.00
IUUC-Ont-071574	Oreochromis niloticus	31.63	6.00e-111	393.00
IUUC-Oan-072826	Ornithorhynchus anatinus	30.15	6.00e-114	403.00
IUUC-Ocu-073995	Oryctolagus cuniculus	32.23	8.00e-117	412.00
IUUC-Oba-075407	Oryza barthii	28.20	1.00e-89	322.00
IUUC-Obr-076451	Oryza brachyantha	30.17	2.00e-113	401.00
IUUC-Ogl-077535	Oryza glaberrima	29.70	1.00e-110	392.00
IUUC-Ogu-077995	Oryza glumaepatula	27.65	1.00e-86	312.00
IUUC-Oin-079431	Oryza indica	29.73	1.00e-111	395.00
IUUC-Olo-080495	Oryza longistaminata	28.42	4.00e-93	333.00
IUUC-Oni-082336	Oryza nivara	28.71	2.00e-103	368.00
IUUC-Opu-084028	Oryza punctata	28.51	2.00e-92	331.00
IUUC-Oru-084500	Oryza rufipogon	27.78	7.00e-87	313.00
IUUC-Osa-086242	Oryza sativa	29.73	5.00e-112	397.00
IUUC-Ola-086612	Oryzias latipes	29.89	5.00e-84	303.00
IUUC-Olu-087703	Ostreococcus lucimarinus	28.68	7.00e-76	276.00
IUUC-Oga-088572	Otolemur garnettii	31.86	6.00e-120	423.00
IUUC-Oar-090363	Ovis aries	31.58	7.00e-123	432.00
IUUC-Ptr-090477	Pan troglodytes	31.72	5.00e-120	423.00
IUUC-Pan-092914	Papio anubis	31.83	7.00e-122	429.00
IUUC-Psi-093019	Pelodiscus sinensis	29.72	2.00e-109	387.00
IUUC-Pma-094303	Petromyzon marinus	29.34	2.00e-88	318.00
IUUC-Pno-094938	Phaeosphaeria nodorum	34.57	2.00e-114	404.00
IUUC-Ppa-095720	Physcomitrella patens	27.43	2.00e-95	342.00
IUUC-Pfo-097034	Poecilia formosa	30.31	5.00e-104	370.00
IUUC-Pab-097669	Pongo abelii	31.72	2.00e-122	431.00
IUUC-Pop-098835	Populus trichocarpa	31.91	4.00e-121	427.00
IUUC-Pca-101097	Procavia capensis	42.51	2.00e-51	195.00
IUUC-Ppe-101430	Prunus persica	29.49	7.00e-115	406.00
IUUC-Pva-103152	Pteropus vampyrus	31.65	1.00e-121	428.00
IUUC-Pgr-103517	Puccinia graminis	28.70	4.00e-106	377.00
IUUC-Ptt-103697	Puccinia triticina	28.50	1.00e-89	322.00
IUUC-Pte-104121	Pyrenophora teres	33.91	4.00e-133	467.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	34.20	3.00e-134	470.00
IUUC-Rno-105435	Rattus norvegicus	31.37	1.00e-123	435.00
IUUC-Sha-107272	Sarcophilus harrisii	30.48	3.00e-107	380.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	38.52	5.00e-171	592.00
IUUC-Spo-108256	Schizosaccharomyces pombe	40.06	0.00e+00	626.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	34.65	2.00e-156	544.00
IUUC-Smo-108762	Selaginella moellendorffii	29.60	4.00e-106	377.00
IUUC-Sit-110051	Setaria italica	29.54	4.00e-106	377.00
IUUC-Sly-111181	Solanum lycopersicum	30.66	1.00e-112	398.00
IUUC-Stu-112018	Solanum tuberosum	30.90	2.00e-112	398.00
IUUC-Sar-113348	Sorex araneus	32.28	4.00e-89	320.00
IUUC-Sbi-114282	Sorghum bicolor	29.67	1.00e-109	388.00
IUUC-Sre-114946	Sporisorium reilianum	28.77	4.00e-77	281.00
IUUC-Ssc-115287	Sus scrofa	32.01	1.00e-121	429.00
IUUC-Tgu-117138	Taeniopygia guttata	28.24	2.00e-89	321.00
IUUC-Tru-118232	Takifugu rubripes	32.02	2.00e-111	394.00
IUUC-Tsy-119502	Tarsius syrichta	26.07	2.00e-75	275.00
IUUC-Tni-120378	Tetraodon nigroviridis	30.68	4.00e-105	374.00
IUUC-Tca-121506	Theobroma cacao	31.34	4.00e-110	390.00
IUUC-Tre-122166	Trichoderma reesei	34.09	6.00e-150	523.00
IUUC-Tvi-122385	Trichoderma virens	34.70	5.00e-155	540.00
IUUC-Tae-122836	Triticum aestivum	30.31	3.00e-119	421.00
IUUC-Tur-126490	Triticum urartu	30.40	3.00e-91	328.00
IUUC-Tme-127157	Tuber melanosporum	36.50	3.00e-141	493.00
IUUC-Tbe-127981	Tupaia belangeri	32.76	3.00e-106	377.00
IUUC-Ttr-128886	Tursiops truncatus	30.99	2.00e-115	408.00
IUUC-Uma-129439	Ustilago maydis	28.00	5.00e-83	300.00
IUUC-Vda-129760	Verticillium dahliae	33.80	2.00e-144	504.00
IUUC-Vpa-130456	Vicugna pacos	31.25	1.00e-118	418.00
IUUC-Vvi-131086	Vitis vinifera	31.09	8.00e-113	399.00
IUUC-Xtr-131829	Xenopus tropicalis	31.04	9.00e-123	432.00
IUUC-Xma-133588	Xiphophorus maculatus	30.03	2.00e-102	365.00
IUUC-Yli-134328	Yarrowia lipolytica	43.31	0.00e+00	743.00
IUUC-Zma-135808	Zea mays	29.86	2.00e-106	377.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence