iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.00e-21	71.8	168	201
UBD/Beta-Prp	1.10e-49	167.6	36	260

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf....sdtllvsGsdDgtikvWDlrtg 33
           td v+ l+f    + +l+++Gs+Dg i+++D+r+ 
   Q: 168  TDYVRTLSFipaaP-HLVATGSYDGLIRLYDTRSS 201
           799*******7655.78899***********9876 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlkghedsvlslsfsps 105
            ++h sv + + f p+ ++ ++   + ++++++ +t ++++++s  ++ v++ +f +dgk+l  g   +++ v+ +++ ++++ ++++ ++    ++f+ +
   Q: 36   VKEHNSVTH-ISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYdSYNPRTILLSINASTHPTHVTKFHTQ 135
           455555555.99966666544444499***********************************************767788899999999999999999995 PP
   S: 106  g.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls.fdsngkelvsgsldgt 203
           + + l+++s+dr+ r+wd+++ ++ +  l+g ++ v+++++ p +  l+++Gs+D+ +rl+d ++       + +h+++v+ ++ +++  +++vs++ ++ 
   Q: 136  DnKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAApHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIaVSP--TQIVSCGGNNF 234
           54999********************999***********************************999888888889*****99985777..78*****9875 PP
   S: 204  vklwdlqtgecvrtlnghtdnvksvrf 230
            k+wdl +++ +++  + ++ v++++ 
   Q: 235  -KVWDLTSNKKLYERGNFNKAVTCLDY 260
           .********999999999999988865 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).

Protein Sequence
(Fasta)

MSTARPRIIT SKAPLLPQQT TPEQRYWRQY TSAQLVKEHN SVTHISFNPQ HPHDFAVTSS 60
TRVQIFSSRT RQVIKTFSRF KDVVYSASFR SDGKLLCAGD ATGLVSVYDS YNPRTILLSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGACTG CTAGGCCTAG AATAATCACT TCGAAGGCTC CATTATTGCC TCAACAGACT 60
ACCCCGGAGC AGCGTTACTG GCGTCAATAC ACTTCCGCAC AACTGGTTAA AGAACATAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0804--Transcription
KW-0853--WD repeat

Interpro

IPR018983--U3_snoRNA-assocProt_15_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09384--UTP15_C
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0033553--C:rDNA heterochromatin
GO:0032040--C:small-subunit processome
GO:0034455--C:t-UTP complex
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0045943--P:positive regulation of transcription from RNA polymerase I promoter
GO:0031167--P:rRNA methylation
GO:0006351--P:transcription, DNA-templated

KEGG

sce:YMR093W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002117	Ailuropoda melanoleuca	30.06	2.00e-64	238.00
IUUC-Atr-003068	Amborella trichopoda	30.49	8.00e-43	166.00
IUUC-Apl-003926	Anas platyrhynchos	30.35	3.00e-55	207.00
IUUC-Aca-004271	Anolis carolinensis	30.56	5.00e-60	223.00
IUUC-Aly-005525	Arabidopsis lyrata	28.49	2.00e-40	157.00
IUUC-Ath-006954	Arabidopsis thaliana	27.59	5.00e-38	150.00
IUUC-Ago-007973	Ashbya gossypii	71.62	0.00e+00	800.00
IUUC-Acl-008287	Aspergillus clavatus	29.37	4.00e-49	186.00
IUUC-Afl-008504	Aspergillus flavus	30.06	2.00e-65	241.00
IUUC-Afu-008983	Aspergillus fumigatus	30.11	3.00e-43	167.00
IUUC-Ani-009315	Aspergillus nidulans	29.31	3.00e-52	197.00
IUUC-Ang-009690	Aspergillus niger	29.44	1.00e-58	219.00
IUUC-Aor-010181	Aspergillus oryzae	30.06	2.00e-65	241.00
IUUC-Ate-010498	Aspergillus terreus	30.13	6.00e-57	213.00
IUUC-Ame-011814	Astyanax mexicanus	31.08	8.00e-66	242.00
IUUC-Bgr-012273	Blumeria graminis	33.90	2.00e-76	278.00
IUUC-Bta-013068	Bos taurus	30.89	2.00e-63	234.00
IUUC-Bci-013930	Botrytis cinerea	34.65	1.00e-79	288.00
IUUC-Bdi-014876	Brachypodium distachyon	28.24	3.00e-40	157.00
IUUC-Bol-015366	Brassica oleracea	29.17	1.00e-38	152.00
IUUC-Bra-017589	Brassica rapa	27.72	6.00e-37	146.00
IUUC-Cel-018159	Caenorhabditis elegans	23.77	3.00e-28	117.00
IUUC-Cja-019139	Callithrix jacchus	30.60	4.00e-64	236.00
IUUC-Cfa-020742	Canis familiaris	29.92	4.00e-61	226.00
IUUC-Cpo-021707	Cavia porcellus	30.62	8.00e-65	239.00
IUUC-Cre-022665	Chlamydomonas reinhardtii	34.85	1.00e-63	235.00
IUUC-Csa-023024	Chlorocebus sabaeus	30.43	3.00e-64	237.00
IUUC-Cho-024487	Choloepus hoffmanni	36.44	5.00e-36	143.00
IUUC-Cin-025294	Ciona intestinalis	35.06	2.00e-72	264.00
IUUC-Cgl-026388	Colletotrichum gloeosporioides	31.26	1.00e-49	188.00
IUUC-Cne-026945	Cryptococcus neoformans	32.08	1.00e-62	231.00
IUUC-Cme-027108	Cyanidioschyzon merolae	26.29	2.00e-32	131.00
IUUC-Dre-028316	Danio rerio	32.31	8.00e-69	252.00
IUUC-Dno-028985	Dasypus novemcinctus	29.73	2.00e-61	227.00
IUUC-Dor-030219	Dipodomys ordii	24.04	9.00e-20	89.00
IUUC-Dse-031495	Dothistroma septosporum	27.82	5.00e-46	176.00
IUUC-Dme-031769	Drosophila melanogaster	31.14	3.00e-54	204.00
IUUC-Ete-032630	Echinops telfairi	37.21	2.00e-43	167.00
IUUC-Eca-033816	Equus caballus	30.89	3.00e-64	237.00
IUUC-Eeu-034840	Erinaceus europaeus	39.91	4.00e-40	157.00
IUUC-Fca-035751	Felis catus	30.50	3.00e-65	240.00
IUUC-Fal-036733	Ficedula albicollis	30.12	3.00e-63	234.00
IUUC-Fox-037743	Fusarium oxysporum	32.12	5.00e-65	239.00
IUUC-Fso-038395	Fusarium solani	31.74	6.00e-65	239.00
IUUC-Gmo-038803	Gadus morhua	33.41	4.00e-57	213.00
IUUC-Ggr-040092	Gaeumannomyces graminis	29.48	5.00e-53	200.00
IUUC-Gga-040714	Gallus gallus	29.65	3.00e-60	223.00
IUUC-Gac-042640	Gasterosteus aculeatus	29.83	1.00e-60	225.00
IUUC-Gma-044192	Glycine max	31.70	3.00e-44	171.00
IUUC-Ggo-045616	Gorilla gorilla	30.23	7.00e-64	236.00
IUUC-Hsa-046720	Homo sapiens	30.61	1.00e-60	225.00
IUUC-Itr-048796	Ictidomys tridecemlineatus	30.29	2.00e-64	238.00
IUUC-Kpa-049291	Komagataella pastoris	51.84	5.00e-154	535.00
IUUC-Lch-049729	Latimeria chalumnae	29.48	7.00e-59	219.00
IUUC-Lpe-051141	Leersia perrieri	25.28	2.00e-38	151.00
IUUC-Loc-051756	Lepisosteus oculatus	32.38	4.00e-69	253.00
IUUC-Lma-053083	Leptosphaeria maculans	32.02	2.00e-57	214.00
IUUC-Laf-054067	Loxodonta africana	31.47	2.00e-64	238.00
IUUC-Mcc-055096	Macaca mulatta	30.43	3.00e-64	237.00
IUUC-Meu-056604	Macropus eugenii	31.20	5.00e-46	176.00
IUUC-Mor-057186	Magnaporthe oryzae	31.02	9.00e-60	222.00
IUUC-Mtr-058346	Medicago truncatula	29.51	5.00e-45	173.00
IUUC-Mla-059116	Melampsora laricipopulina	31.87	1.00e-62	231.00
IUUC-Mga-060038	Meleagris gallopavo	25.90	2.00e-31	127.00
IUUC-Mvi-060272	Microbotryum violaceum	31.37	3.00e-65	240.00
IUUC-Mmr-060877	Microcebus murinus	30.81	2.00e-64	238.00
IUUC-Mdo-062168	Monodelphis domestica	31.06	2.00e-58	218.00
IUUC-Mmu-063441	Mus musculus	29.92	1.00e-62	231.00
IUUC-Mac-065330	Musa acuminata	27.81	8.00e-29	119.00
IUUC-Mpu-065704	Mustela putorius furo	30.50	2.00e-65	241.00
IUUC-Mlu-067640	Myotis lucifugus	31.27	8.00e-66	242.00
IUUC-Nfi-068589	Neosartorya fischeri	30.11	3.00e-43	167.00
IUUC-Ncr-068769	Neurospora crassa	30.14	9.00e-58	215.00
IUUC-Nle-069105	Nomascus leucogenys	31.14	1.00e-59	221.00
IUUC-Opr-070203	Ochotona princeps	31.40	7.00e-70	256.00
IUUC-Ont-072054	Oreochromis niloticus	31.95	9.00e-65	239.00
IUUC-Oan-073624	Ornithorhynchus anatinus	32.03	1.00e-52	198.00
IUUC-Ocu-074326	Oryctolagus cuniculus	30.43	2.00e-62	231.00
IUUC-Obr-076038	Oryza brachyantha	26.51	4.00e-32	130.00
IUUC-Ogl-077463	Oryza glaberrima	25.83	2.00e-36	144.00
IUUC-Ogu-078631	Oryza glumaepatula	25.93	3.00e-39	154.00
IUUC-Oin-079242	Oryza indica	26.03	1.00e-36	145.00
IUUC-Olo-080652	Oryza longistaminata	25.78	4.00e-36	144.00
IUUC-Ome-081109	Oryza meridionalis	24.71	4.00e-28	118.00
IUUC-Oni-082187	Oryza nivara	26.03	1.00e-36	145.00
IUUC-Opu-083995	Oryza punctata	25.58	4.00e-30	124.00
IUUC-Oru-084962	Oryza rufipogon	26.03	4.00e-30	124.00
IUUC-Osa-086201	Oryza sativa	26.03	4.00e-30	124.00
IUUC-Ola-087115	Oryzias latipes	30.69	8.00e-61	226.00
IUUC-Olu-087842	Ostreococcus lucimarinus	28.68	3.00e-45	174.00
IUUC-Oga-088204	Otolemur garnettii	30.12	1.00e-62	231.00
IUUC-Oar-089297	Ovis aries	29.87	5.00e-62	229.00
IUUC-Ptr-090953	Pan troglodytes	30.43	3.00e-64	237.00
IUUC-Pan-092451	Papio anubis	30.22	3.00e-63	233.00
IUUC-Psi-092999	Pelodiscus sinensis	30.35	4.00e-63	233.00
IUUC-Pma-094304	Petromyzon marinus	28.82	3.00e-48	184.00
IUUC-Pno-095060	Phaeosphaeria nodorum	31.82	1.00e-59	221.00
IUUC-Ppa-095433	Physcomitrella patens	34.91	7.00e-69	252.00
IUUC-Pfo-096433	Poecilia formosa	29.39	2.00e-59	221.00
IUUC-Pab-098677	Pongo abelii	30.43	2.00e-64	238.00
IUUC-Pop-099329	Populus trichocarpa	34.70	5.00e-40	156.00
IUUC-Pca-100444	Procavia capensis	38.37	3.00e-43	167.00
IUUC-Ppe-101318	Prunus persica	28.27	4.00e-50	190.00
IUUC-Pva-102162	Pteropus vampyrus	36.53	2.00e-36	144.00
IUUC-Pgr-103329	Puccinia graminis	29.72	3.00e-61	227.00
IUUC-Ptt-103837	Puccinia triticina	28.70	4.00e-61	227.00
IUUC-Pte-104133	Pyrenophora teres	33.14	2.00e-67	247.00
IUUC-Pyt-104675	Pyrenophora triticirepentis	32.95	1.00e-66	245.00
IUUC-Rno-105004	Rattus norvegicus	29.46	6.00e-62	229.00
IUUC-Sha-107199	Sarcophilus harrisii	31.01	4.00e-63	233.00
IUUC-Sja-107670	Schizosaccharomyces japonicus	36.05	7.00e-87	312.00
IUUC-Spo-108125	Schizosaccharomyces pombe	35.12	2.00e-85	307.00
IUUC-Ssl-108534	Sclerotinia sclerotiorum	35.03	8.00e-81	292.00
IUUC-Smo-109588	Selaginella moellendorffii	31.62	1.00e-65	241.00
IUUC-Sit-110043	Setaria italica	24.36	3.00e-22	97.40
IUUC-Stu-112396	Solanum tuberosum	29.55	1.00e-46	178.00
IUUC-Sar-113359	Sorex araneus	28.48	1.00e-29	121.00
IUUC-Sre-114995	Sporisorium reilianum	31.09	5.00e-66	243.00
IUUC-Ssc-115397	Sus scrofa	31.29	2.00e-65	241.00
IUUC-Tgu-116834	Taeniopygia guttata	30.12	8.00e-65	239.00
IUUC-Tru-118764	Takifugu rubripes	31.59	2.00e-67	247.00
IUUC-Tsy-119118	Tarsius syrichta	30.31	1.00e-63	234.00
IUUC-Tni-120053	Tetraodon nigroviridis	31.69	4.00e-67	246.00
IUUC-Tca-121842	Theobroma cacao	26.98	2.00e-39	154.00
IUUC-Tre-122172	Trichoderma reesei	32.08	1.00e-65	242.00
IUUC-Tvi-122288	Trichoderma virens	31.83	9.00e-55	205.00
IUUC-Tae-125722	Triticum aestivum	26.61	4.00e-25	107.00
IUUC-Tur-126846	Triticum urartu	30.51	2.00e-09	54.30
IUUC-Tme-127164	Tuber melanosporum	33.07	9.00e-80	288.00
IUUC-Tbe-127458	Tupaia belangeri	31.06	3.00e-60	223.00
IUUC-Ttr-128680	Tursiops truncatus	29.92	4.00e-62	229.00
IUUC-Uma-129508	Ustilago maydis	31.45	5.00e-65	239.00
IUUC-Vda-129696	Verticillium dahliae	35.96	3.00e-50	190.00
IUUC-Vpa-130820	Vicugna pacos	31.49	4.00e-67	246.00
IUUC-Vvi-131126	Vitis vinifera	30.56	3.00e-55	207.00
IUUC-Xtr-131826	Xenopus tropicalis	31.41	7.00e-65	239.00
IUUC-Xma-133373	Xiphophorus maculatus	29.76	9.00e-61	225.00
IUUC-Yli-134432	Yarrowia lipolytica	44.89	4.00e-118	416.00
IUUC-Zma-135241	Zea mays	26.88	5.00e-35	140.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence