iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051794

Ensembl Protein ID

ENSLOCP00000010214.1

UniProt Accession

W5MPA5; W5MPA5_LEPOC

Genbank Protein ID

ENSLOCP00000010214

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01015377

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000008405.1	ENSLOCT00000010227.1	ENSLOCP00000010214.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-43	143.8	203	239
UBD/Beta-Prp	5.40e-68	229.5	296	491

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+++a  ++   +v+Gs D tik+WDl +g+l
   Q: 203  GHLGWVRSIAVePGnQWFVTGSADRTIKIWDLASGKL 239
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 17   kfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsps 105
           + +p  ++l+t srd+t +vwd++t+  +++lsgh+++v++vk+++ ++ ++tgs D ti++wdl +gk+ +tl++h++sv++l ++p 
   Q: 296  DLHPTIDVLVTCSRDSTARVWDIRTKANVHTLSGHTNTVATVKCQSAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRALVLHPR 384
           55777889999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 106  gdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.......tgghtdsvysls 187
           +++++sGs d+ i+ w+ + g  ++  lsgh++++n+++v++ + +lvsG++++t+ +Wd +tg   ++        + + ++ +    
   Q: 385  QYTFASGSPDN-IKQWKFPDGNFIQ-NLSGHNAIINTLAVNS-DGVLVSGADNGTIHMWDWRTGYNFQRIhaavqpgSLDSESGIFACV 470
           99999999665.8999999999999.9999999999999999.6789999999999999999998888887655555333455555555 PP
   S: 188  fdsngkelvsgsldgtvklwd 208
           fd++  +l+++  d+t+k++ 
   Q: 471  FDHSESRLITAEADKTIKVYR 491
           999999999999999999985 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADHA KPIDMDEESH KVKMAVKLRT EYSAVLHMPV 60
FKEGKDKGSL QISDPYGQQN FSANPGHDPE YLITGTHPYP SGPGIALTAD TQVQKMPSDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCTTCCT CCTGTATTCA TATTGTGTGC GCGCTGTTAT TTGTCGGTGG TACGTTTTCG 60
AATAGTTAAA AAAAAATATA TTTAAAAAAG TAATCGAGTG AAAAGGATTT GTCTTCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0043066--P:negative regulation of apoptotic process
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	48.13	3.00e-126	445.00
IUUC-Aml-001605	Ailuropoda melanoleuca	81.82	0.00e+00	855.00
IUUC-Atr-002757	Amborella trichopoda	48.79	6.00e-128	450.00
IUUC-Apl-003198	Anas platyrhynchos	84.71	0.00e+00	898.00
IUUC-Aca-004683	Anolis carolinensis	84.91	0.00e+00	897.00
IUUC-Aly-005775	Arabidopsis lyrata	62.42	6.00e-123	434.00
IUUC-Ath-007460	Arabidopsis thaliana	62.11	3.00e-122	431.00
IUUC-Ago-007884	Ashbya gossypii	50.46	1.00e-100	359.00
IUUC-Acl-008153	Aspergillus clavatus	67.96	2.00e-126	445.00
IUUC-Afl-008384	Aspergillus flavus	59.63	1.00e-127	449.00
IUUC-Afu-009045	Aspergillus fumigatus	68.61	1.00e-127	449.00
IUUC-Ani-009229	Aspergillus nidulans	66.98	7.00e-127	447.00
IUUC-Ang-009812	Aspergillus niger	68.79	1.00e-120	425.00
IUUC-Aor-010059	Aspergillus oryzae	59.63	1.00e-127	449.00
IUUC-Ate-010351	Aspergillus terreus	68.61	1.00e-132	466.00
IUUC-Ame-011613	Astyanax mexicanus	64.73	2.00e-163	568.00
IUUC-Bgr-012042	Blumeria graminis	58.42	5.00e-132	464.00
IUUC-Bta-012406	Bos taurus	81.69	0.00e+00	850.00
IUUC-Bci-013760	Botrytis cinerea	65.53	3.00e-128	451.00
IUUC-Bdi-014776	Brachypodium distachyon	57.14	1.00e-128	453.00
IUUC-Bol-016189	Brassica oleracea	48.33	2.00e-122	432.00
IUUC-Bra-018044	Brassica rapa	48.54	4.00e-123	434.00
IUUC-Cel-018651	Caenorhabditis elegans	53.91	6.00e-148	517.00
IUUC-Cja-019974	Callithrix jacchus	82.29	0.00e+00	857.00
IUUC-Cfa-021085	Canis familiaris	81.89	0.00e+00	859.00
IUUC-Cpo-021458	Cavia porcellus	82.09	0.00e+00	860.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	60.68	2.00e-122	432.00
IUUC-Csa-023883	Chlorocebus sabaeus	81.49	0.00e+00	849.00
IUUC-Cho-024623	Choloepus hoffmanni	78.76	0.00e+00	844.00
IUUC-Cin-025190	Ciona intestinalis	61.20	9.00e-178	616.00
IUUC-Csv-026367	Ciona savignyi	61.00	5.00e-176	610.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	68.06	3.00e-135	475.00
IUUC-Cne-027069	Cryptococcus neoformans	50.52	4.00e-131	461.00
IUUC-Cme-027233	Cyanidioschyzon merolae	29.65	6.00e-35	141.00
IUUC-Dre-028260	Danio rerio	87.90	0.00e+00	912.00
IUUC-Dno-029112	Dasypus novemcinctus	82.29	0.00e+00	858.00
IUUC-Dor-031118	Dipodomys ordii	84.95	0.00e+00	700.00
IUUC-Dse-031493	Dothistroma septosporum	46.98	4.00e-122	431.00
IUUC-Dme-032138	Drosophila melanogaster	78.10	5.00e-150	524.00
IUUC-Ete-032411	Echinops telfairi	72.01	0.00e+00	689.00
IUUC-Eca-033521	Equus caballus	82.49	0.00e+00	866.00
IUUC-Eeu-035249	Erinaceus europaeus	73.21	2.00e-165	575.00
IUUC-Fca-036358	Felis catus	81.49	0.00e+00	854.00
IUUC-Fal-036933	Ficedula albicollis	84.91	0.00e+00	892.00
IUUC-Fox-037713	Fusarium oxysporum	65.03	1.00e-133	469.00
IUUC-Fso-038380	Fusarium solani	65.85	5.00e-134	471.00
IUUC-Gmo-039133	Gadus morhua	85.89	0.00e+00	877.00
IUUC-Ggr-039915	Gaeumannomyces graminis	68.39	2.00e-127	449.00
IUUC-Gga-041176	Gallus gallus	83.70	0.00e+00	890.00
IUUC-Gac-042344	Gasterosteus aculeatus	84.48	0.00e+00	880.00
IUUC-Gma-043328	Glycine max	51.59	7.00e-130	457.00
IUUC-Ggo-044478	Gorilla gorilla	81.29	0.00e+00	846.00
IUUC-Hsa-046037	Homo sapiens	81.49	0.00e+00	848.00
IUUC-Hvu-047349	Hordeum vulgare	51.79	7.00e-131	460.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	82.29	0.00e+00	860.00
IUUC-Kpa-049343	Komagataella pastoris	60.70	1.00e-117	416.00
IUUC-Lch-049830	Latimeria chalumnae	86.49	0.00e+00	902.00
IUUC-Lpe-051442	Leersia perrieri	49.27	3.00e-128	451.00
IUUC-Lma-053137	Leptosphaeria maculans	45.88	7.00e-124	437.00
IUUC-Laf-053471	Loxodonta africana	81.62	0.00e+00	855.00
IUUC-Mcc-055627	Macaca mulatta	81.49	0.00e+00	850.00
IUUC-Meu-056148	Macropus eugenii	74.49	0.00e+00	768.00
IUUC-Mor-056960	Magnaporthe oryzae	68.30	5.00e-132	464.00
IUUC-Mtr-057816	Medicago truncatula	49.00	3.00e-125	441.00
IUUC-Mla-059031	Melampsora laricipopulina	67.61	5.00e-130	457.00
IUUC-Mga-059337	Meleagris gallopavo	84.04	0.00e+00	892.00
IUUC-Mvi-060217	Microbotryum violaceum	66.98	7.00e-132	464.00
IUUC-Mmr-061018	Microcebus murinus	82.90	0.00e+00	867.00
IUUC-Mdo-062863	Monodelphis domestica	84.10	0.00e+00	869.00
IUUC-Mmu-063988	Mus musculus	81.69	0.00e+00	848.00
IUUC-Mac-064459	Musa acuminata	47.17	3.00e-119	422.00
IUUC-Mpu-066559	Mustela putorius furo	82.09	0.00e+00	861.00
IUUC-Mlu-067521	Myotis lucifugus	81.49	0.00e+00	854.00
IUUC-Nfi-068492	Neosartorya fischeri	68.93	1.00e-127	449.00
IUUC-Ncr-068808	Neurospora crassa	61.92	6.00e-132	464.00
IUUC-Nle-069875	Nomascus leucogenys	81.69	0.00e+00	851.00
IUUC-Opr-070462	Ochotona princeps	91.73	7.00e-150	523.00
IUUC-Ont-071365	Oreochromis niloticus	86.09	0.00e+00	898.00
IUUC-Oan-072708	Ornithorhynchus anatinus	85.25	0.00e+00	897.00
IUUC-Ocu-074594	Oryctolagus cuniculus	81.69	0.00e+00	855.00
IUUC-Oba-075570	Oryza barthii	48.15	4.00e-125	441.00
IUUC-Obr-076366	Oryza brachyantha	66.95	2.00e-94	338.00
IUUC-Ogl-077153	Oryza glaberrima	48.15	3.00e-124	438.00
IUUC-Ogu-078540	Oryza glumaepatula	48.15	5.00e-125	441.00
IUUC-Oin-079612	Oryza indica	47.66	5.00e-123	434.00
IUUC-Olo-081077	Oryza longistaminata	47.66	5.00e-123	434.00
IUUC-Ome-081236	Oryza meridionalis	63.00	5.00e-122	431.00
IUUC-Oni-082499	Oryza nivara	48.15	5.00e-125	441.00
IUUC-Opu-083499	Oryza punctata	47.66	3.00e-123	435.00
IUUC-Oru-084276	Oryza rufipogon	48.15	5.00e-125	441.00
IUUC-Osa-085849	Oryza sativa	48.15	5.00e-125	441.00
IUUC-Ola-086655	Oryzias latipes	81.93	0.00e+00	849.00
IUUC-Olu-087637	Ostreococcus lucimarinus	60.62	6.00e-119	420.00
IUUC-Oga-087934	Otolemur garnettii	82.53	0.00e+00	861.00
IUUC-Oar-090185	Ovis aries	80.92	0.00e+00	841.00
IUUC-Ptr-091198	Pan troglodytes	81.69	0.00e+00	851.00
IUUC-Pan-092622	Papio anubis	81.49	0.00e+00	849.00
IUUC-Psi-093320	Pelodiscus sinensis	83.53	0.00e+00	886.00
IUUC-Pma-094638	Petromyzon marinus	80.20	0.00e+00	837.00
IUUC-Pno-094826	Phaeosphaeria nodorum	51.54	1.00e-99	356.00
IUUC-Ppa-095576	Physcomitrella patens	48.33	4.00e-121	428.00
IUUC-Pfo-096894	Poecilia formosa	83.73	0.00e+00	868.00
IUUC-Pab-098020	Pongo abelii	81.89	0.00e+00	852.00
IUUC-Pop-099180	Populus trichocarpa	48.90	1.00e-124	439.00
IUUC-Pca-100909	Procavia capensis	76.75	0.00e+00	695.00
IUUC-Ppe-101346	Prunus persica	47.99	9.00e-123	433.00
IUUC-Pva-102167	Pteropus vampyrus	67.61	0.00e+00	664.00
IUUC-Pgr-103516	Puccinia graminis	51.87	7.00e-134	470.00
IUUC-Ptt-103738	Puccinia triticina	53.24	2.00e-134	472.00
IUUC-Pte-104352	Pyrenophora teres	59.94	1.00e-125	443.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	60.56	9.00e-127	446.00
IUUC-Rno-105291	Rattus norvegicus	81.89	0.00e+00	852.00
IUUC-Sce-106204	Saccharomyces cerevisiae	50.48	4.00e-99	355.00
IUUC-Sha-106943	Sarcophilus harrisii	83.53	0.00e+00	861.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	64.26	5.00e-127	447.00
IUUC-Spo-108049	Schizosaccharomyces pombe	66.46	4.00e-131	461.00
IUUC-Smo-109043	Selaginella moellendorffii	63.47	6.00e-124	436.00
IUUC-Sit-110431	Setaria italica	50.31	4.00e-128	451.00
IUUC-Sly-111391	Solanum lycopersicum	63.70	1.00e-116	413.00
IUUC-Stu-112364	Solanum tuberosum	57.57	2.00e-98	352.00
IUUC-Sar-113450	Sorex araneus	91.52	0.00e+00	643.00
IUUC-Sbi-113829	Sorghum bicolor	51.04	1.00e-129	456.00
IUUC-Sre-115153	Sporisorium reilianum	61.59	4.00e-122	431.00
IUUC-Ssc-115798	Sus scrofa	81.53	0.00e+00	852.00
IUUC-Tgu-117417	Taeniopygia guttata	85.02	0.00e+00	894.00
IUUC-Tru-117615	Takifugu rubripes	81.58	0.00e+00	813.00
IUUC-Tsy-119480	Tarsius syrichta	82.19	0.00e+00	847.00
IUUC-Tni-119847	Tetraodon nigroviridis	82.04	0.00e+00	851.00
IUUC-Tca-121287	Theobroma cacao	48.10	1.00e-126	446.00
IUUC-Tre-122010	Trichoderma reesei	67.68	2.00e-139	489.00
IUUC-Tvi-122475	Trichoderma virens	66.26	4.00e-138	484.00
IUUC-Tae-124243	Triticum aestivum	51.80	2.00e-130	459.00
IUUC-Tur-126116	Triticum urartu	49.87	2.00e-98	352.00
IUUC-Tme-126992	Tuber melanosporum	67.31	3.00e-131	461.00
IUUC-Tbe-127803	Tupaia belangeri	74.83	0.00e+00	652.00
IUUC-Ttr-128933	Tursiops truncatus	81.89	0.00e+00	854.00
IUUC-Uma-129447	Ustilago maydis	60.88	6.00e-118	417.00
IUUC-Vda-129780	Verticillium dahliae	66.25	4.00e-134	471.00
IUUC-Vpa-130557	Vicugna pacos	68.83	5.00e-89	321.00
IUUC-Vvi-130918	Vitis vinifera	47.00	5.00e-120	424.00
IUUC-Xtr-132409	Xenopus tropicalis	83.90	0.00e+00	850.00
IUUC-Xma-133420	Xiphophorus maculatus	83.47	0.00e+00	867.00
IUUC-Yli-134362	Yarrowia lipolytica	54.12	3.00e-120	425.00
IUUC-Zma-135804	Zea mays	63.11	2.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence