iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108272

Ensembl Protein ID

SPBC1306.02.1:pep

UniProt Accession

Q9USZ0; WDR6_SCHPO

Genbank Protein ID

CAB62092.1

Protein Name

Uncharacterized WD repeat-containing protein C1306.02

Genbank Nucleotide ID

CU329671

Gene Name

rtt10; SPBC1306.02; SPBC4.08

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC1306.02	SPBC1306.02.1	SPBC1306.02.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-30	101.4	192	223
UBD/Beta-Prp	2.70e-51	172.6	148	441

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH++  ++l+f sd ++l+s s D t+++W++
   Q: 192  GHEGACFDLKFsSDgRYLCSVSEDRTLRLWSI 223
           89**********999***************96 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkl.....lrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.gheds 96
           ++  v++s ++ ++a++s+ + i vw++   +      + ++  ghe++  ++kfs+dg +l ++seDrt+++w++++++ +++   gh+++
   Q: 148  FCATVQISGNEIYIASASAFQQIYVWKFNYNNPpscvsIDTYlVGHEGACFDLKFSSDGRYLCSVSEDRTLRLWSIESSPFLIATGfGHSAR 239
           6778999********************9987778889977766**********************************9998887766***** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdg.vvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgghtdsv 183
           v+ + f p ++ +++ s+d t+r+w ++ ++  ++ t +gh+g  ++++vv++ + ++ +G++D+ vr Wd     +++++   +   t++ 
   Q: 240  VWRCVFLP-NKEIATVSEDLTLRLWTWNDKTLTNTyTYTGHRGkHIWSLVVSSANPIIYTGGNDGSVRSWDYktrIQESCISVSSL-FTSKT 329
           ********.999************99998888888888998862699******9******************44434566665533.44444 PP
   S: 184  ysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
              s  f +  + l+  +++g   + d + ++ + +l+  t+ ++ +r ++n+ +++ +s  g+i+++ +++ +llk++ lh+ ++    ++
   Q: 330  LLASfcFVK-CQKLLCLAKNGEMSIIDNKGKKAIPALTT-TSDMSIIRSWKNSFFVAAASNKGTIYVFSYQNTNLLKAIDLHRGKIQQLLTY 419
           433332555.389*******************9999986.677899********************************************** PP
   S: 274  sfgdnvlvlgse...dskvniw 292
           ++++++++l ++    ++++++
   Q: 420  QVKERYFLLSKSfvgKNQFRVY 441
           ****999988776777778877 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

May play a role in the regulation of the retromer complex and in the recycling from endosomes of plasma membrane proteins. May be involved in the methylation of the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)) by SPAC4F10.03c (By similarity).

Protein Sequence
(Fasta)

MLVEGDKGVL EPVNFVGPVT SLALIHNDKF LCCAQGPCLR IYDVSESRHE SDLIKSILLP 60
FHNRIHGMLP CKQGLFVWGG TYFAVVDVET SQVYYDRISD WIFNAAELGE ENKFCVVTSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTTAATG AATAACAAAA TATACATTTT ATATGGAGAA TATATATGTA TTTGCAATTG 60
AATGTTGCTG ATTATTTAAA AGTAGCTTGC TTATCGTCAA GAAAAAAGCG ACTTCGTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0032456--P:endocytic recycling
GO:0008033--P:tRNA processing

KEGG

spo:SPBC1306.02

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000976	Aegilops tauschii	29.46	1.00e-12	67.40
IUUC-Aml-001786	Ailuropoda melanoleuca	21.00	3.00e-19	89.40
IUUC-Atr-003053	Amborella trichopoda	27.64	8.00e-15	74.70
IUUC-Apl-003178	Anas platyrhynchos	26.36	6.00e-28	116.00
IUUC-Aca-004886	Anolis carolinensis	24.72	1.00e-22	100.00
IUUC-Aly-005509	Arabidopsis lyrata	28.79	1.00e-20	94.00
IUUC-Ath-007109	Arabidopsis thaliana	25.47	2.00e-20	93.20
IUUC-Ago-007817	Ashbya gossypii	25.25	2.00e-71	261.00
IUUC-Acl-008020	Aspergillus clavatus	23.80	4.00e-55	208.00
IUUC-Afl-008608	Aspergillus flavus	25.89	4.00e-30	124.00
IUUC-Afu-009035	Aspergillus fumigatus	24.68	2.00e-62	233.00
IUUC-Ani-009359	Aspergillus nidulans	23.83	6.00e-51	194.00
IUUC-Ang-009692	Aspergillus niger	24.29	2.00e-53	202.00
IUUC-Aor-010056	Aspergillus oryzae	25.27	3.00e-57	215.00
IUUC-Ate-010299	Aspergillus terreus	24.73	4.00e-55	208.00
IUUC-Ame-011051	Astyanax mexicanus	23.12	6.00e-24	104.00
IUUC-Bgr-012077	Blumeria graminis	24.64	1.00e-58	219.00
IUUC-Bta-012793	Bos taurus	20.69	5.00e-35	141.00
IUUC-Bci-013679	Botrytis cinerea	23.70	9.00e-35	140.00
IUUC-Bdi-014401	Brachypodium distachyon	26.10	2.00e-14	73.60
IUUC-Bol-015628	Brassica oleracea	35.06	6.00e-20	91.30
IUUC-Bra-017446	Brassica rapa	32.00	1.00e-21	97.10
IUUC-Cja-018910	Callithrix jacchus	21.66	1.00e-39	156.00
IUUC-Cfa-021260	Canis familiaris	20.95	2.00e-34	139.00
IUUC-Cpo-022205	Cavia porcellus	20.43	8.00e-34	137.00
IUUC-Csa-023510	Chlorocebus sabaeus	21.56	2.00e-19	89.40
IUUC-Cgl-026380	Colletotrichum gloeosporioides	24.78	5.00e-41	160.00
IUUC-Dre-028004	Danio rerio	23.24	4.00e-53	201.00
IUUC-Dno-029804	Dasypus novemcinctus	21.42	1.00e-34	140.00
IUUC-Dor-030512	Dipodomys ordii	21.74	4.00e-25	108.00
IUUC-Ete-033076	Echinops telfairi	22.34	1.00e-16	80.10
IUUC-Eca-033727	Equus caballus	21.27	1.00e-28	119.00
IUUC-Eeu-035210	Erinaceus europaeus	21.32	7.00e-30	124.00
IUUC-Fca-035433	Felis catus	21.38	6.00e-37	147.00
IUUC-Fal-036807	Ficedula albicollis	25.90	2.00e-30	125.00
IUUC-Fox-037749	Fusarium oxysporum	27.92	5.00e-35	141.00
IUUC-Fso-038164	Fusarium solani	28.61	9.00e-40	157.00
IUUC-Gmo-039180	Gadus morhua	21.67	5.00e-36	144.00
IUUC-Ggr-039801	Gaeumannomyces graminis	25.35	1.00e-21	97.10
IUUC-Gga-040482	Gallus gallus	25.00	5.00e-25	108.00
IUUC-Gac-042066	Gasterosteus aculeatus	21.88	6.00e-40	157.00
IUUC-Gma-042704	Glycine max	30.90	1.00e-16	80.50
IUUC-Ggo-044942	Gorilla gorilla	21.56	1.00e-19	90.10
IUUC-Hsa-046408	Homo sapiens	21.37	3.00e-37	149.00
IUUC-Hvu-047448	Hordeum vulgare	27.38	6.00e-13	68.20
IUUC-Itr-048756	Ictidomys tridecemlineatus	22.37	1.00e-20	93.60
IUUC-Kpa-049257	Komagataella pastoris	25.17	3.00e-69	254.00
IUUC-Lch-050170	Latimeria chalumnae	23.33	4.00e-52	198.00
IUUC-Lpe-051575	Leersia perrieri	19.71	5.00e-13	68.60
IUUC-Loc-052341	Lepisosteus oculatus	21.34	1.00e-16	80.50
IUUC-Lma-053318	Leptosphaeria maculans	24.15	1.00e-48	186.00
IUUC-Laf-054299	Loxodonta africana	21.80	6.00e-21	94.70
IUUC-Mcc-055438	Macaca mulatta	21.56	3.00e-19	89.00
IUUC-Meu-056206	Macropus eugenii	22.07	1.00e-23	103.00
IUUC-Mor-056928	Magnaporthe oryzae	27.53	3.00e-32	132.00
IUUC-Mtr-058455	Medicago truncatula	29.25	2.00e-16	80.10
IUUC-Mga-059962	Meleagris gallopavo	24.09	8.00e-26	109.00
IUUC-Mvi-060438	Microbotryum violaceum	22.55	2.00e-31	129.00
IUUC-Mmr-061353	Microcebus murinus	22.22	1.00e-20	94.00
IUUC-Mdo-062061	Monodelphis domestica	21.32	4.00e-32	131.00
IUUC-Mmu-064386	Mus musculus	22.40	9.00e-21	94.00
IUUC-Mac-065653	Musa acuminata	22.95	4.00e-24	105.00
IUUC-Mpu-066420	Mustela putorius furo	21.73	2.00e-37	149.00
IUUC-Mlu-068104	Myotis lucifugus	20.63	1.00e-36	146.00
IUUC-Nfi-068301	Neosartorya fischeri	24.66	3.00e-60	225.00
IUUC-Ncr-068718	Neurospora crassa	22.64	8.00e-51	194.00
IUUC-Nle-069836	Nomascus leucogenys	24.86	3.00e-17	82.00
IUUC-Ont-071605	Oreochromis niloticus	22.66	6.00e-52	197.00
IUUC-Oan-073645	Ornithorhynchus anatinus	24.21	1.00e-24	107.00
IUUC-Ocu-074708	Oryctolagus cuniculus	24.86	1.00e-16	80.50
IUUC-Obr-076647	Oryza brachyantha	21.49	3.00e-17	82.40
IUUC-Ogl-077628	Oryza glaberrima	24.41	1.00e-13	70.90
IUUC-Ogu-078209	Oryza glumaepatula	22.15	2.00e-07	50.10
IUUC-Oin-079342	Oryza indica	23.91	2.00e-16	79.70
IUUC-Olo-080623	Oryza longistaminata	24.26	1.00e-13	68.90
IUUC-Ome-081776	Oryza meridionalis	20.52	4.00e-14	72.40
IUUC-Oni-082311	Oryza nivara	23.94	2.00e-16	79.70
IUUC-Opu-083195	Oryza punctata	24.56	1.00e-14	73.90
IUUC-Osa-085317	Oryza sativa	24.41	7.00e-14	71.60
IUUC-Ola-087145	Oryzias latipes	23.37	6.00e-42	164.00
IUUC-Olu-087785	Ostreococcus lucimarinus	28.44	2.00e-17	82.80
IUUC-Oga-088206	Otolemur garnettii	21.78	5.00e-37	147.00
IUUC-Oar-089802	Ovis aries	20.24	1.00e-20	93.60
IUUC-Ptr-091528	Pan troglodytes	20.23	5.00e-25	108.00
IUUC-Pan-092782	Papio anubis	22.52	4.00e-22	98.60
IUUC-Psi-093102	Pelodiscus sinensis	21.86	4.00e-15	74.30
IUUC-Pno-095063	Phaeosphaeria nodorum	23.15	6.00e-37	147.00
IUUC-Ppa-095436	Physcomitrella patens	28.00	2.00e-16	80.10
IUUC-Pfo-097423	Poecilia formosa	21.81	3.00e-36	145.00
IUUC-Pab-097763	Pongo abelii	21.19	3.00e-34	139.00
IUUC-Pop-099090	Populus trichocarpa	29.70	3.00e-16	79.70
IUUC-Pca-100173	Procavia capensis	20.99	1.00e-32	133.00
IUUC-Ppe-101580	Prunus persica	22.70	7.00e-15	75.10
IUUC-Pva-102715	Pteropus vampyrus	20.72	8.00e-33	134.00
IUUC-Pgr-103424	Puccinia graminis	22.37	3.00e-24	105.00
IUUC-Pte-104316	Pyrenophora teres	22.95	8.00e-46	177.00
IUUC-Pyt-104676	Pyrenophora triticirepentis	23.31	1.00e-44	173.00
IUUC-Rno-105122	Rattus norvegicus	22.86	7.00e-22	97.80
IUUC-Sce-106465	Saccharomyces cerevisiae	24.41	5.00e-60	224.00
IUUC-Sha-107208	Sarcophilus harrisii	22.49	4.00e-43	168.00
IUUC-Sja-107771	Schizosaccharomyces japonicus	36.38	0.00e+00	629.00
IUUC-Ssl-108576	Sclerotinia sclerotiorum	23.86	3.00e-36	145.00
IUUC-Smo-108961	Selaginella moellendorffii	23.37	4.00e-17	82.80
IUUC-Sit-109932	Setaria italica	28.16	4.00e-15	75.50
IUUC-Sly-111685	Solanum lycopersicum	22.55	3.00e-20	92.80
IUUC-Sar-112998	Sorex araneus	21.35	1.00e-21	97.10
IUUC-Sbi-114074	Sorghum bicolor	27.71	1.00e-16	80.50
IUUC-Ssc-115619	Sus scrofa	21.52	1.00e-34	140.00
IUUC-Tgu-117485	Taeniopygia guttata	25.85	1.00e-28	119.00
IUUC-Tru-118104	Takifugu rubripes	23.38	2.00e-44	172.00
IUUC-Tni-119995	Tetraodon nigroviridis	21.75	4.00e-37	148.00
IUUC-Tca-121790	Theobroma cacao	20.97	1.00e-18	87.00
IUUC-Tre-122080	Trichoderma reesei	27.54	9.00e-34	137.00
IUUC-Tvi-122306	Trichoderma virens	27.85	1.00e-33	136.00
IUUC-Tae-125371	Triticum aestivum	21.13	2.00e-16	79.70
IUUC-Tur-126473	Triticum urartu	21.43	2.00e-15	76.60
IUUC-Tme-126957	Tuber melanosporum	26.77	1.00e-52	199.00
IUUC-Tbe-128082	Tupaia belangeri	28.66	1.00e-09	56.60
IUUC-Ttr-128387	Tursiops truncatus	24.46	1.00e-15	77.00
IUUC-Vda-129804	Verticillium dahliae	25.49	2.00e-21	95.90
IUUC-Vpa-130257	Vicugna pacos	23.08	3.00e-12	64.70
IUUC-Vvi-131701	Vitis vinifera	23.62	1.00e-19	90.90
IUUC-Xtr-132622	Xenopus tropicalis	22.60	1.00e-50	193.00
IUUC-Xma-134014	Xiphophorus maculatus	23.29	1.00e-42	166.00
IUUC-Yli-134589	Yarrowia lipolytica	25.41	3.00e-63	234.00
IUUC-Zma-135732	Zea mays	23.00	1.00e-21	97.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence