iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062886

UUCD1 version

UUC-MoD-00511

Ensembl Protein ID

ENSMODP00000019871.1

UniProt Accession

F6ZQS0; F6ZQS0_MONDO

Protein Name

Uncharacterized protein

Gene Name

MLST8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000015924.2	ENSMODT00000020226.2	ENSMODP00000019871.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-32	108.7	219	249
UBD/Beta-Prp	2.20e-44	152.0	12	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht     ++f +d tll+++s D t+k+W++
   Q: 219  HTRYALQCRFsPDsTLLATCSADQTCKIWRT 249
           888888999**999***************96 PP

UBD/Beta-Prp

   S: 149  gnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq..tgecvrtlnghtdnvksvrfspnde 235
             +l+++++D tvr+W+  +g + rt +  ++++v+ l+++++ +++++++  + ++++dl   + + v  + g ++n++sv f++++ 
   Q: 12   PVILATAGYDHTVRFWQAHSGICTRTVQH-QDSQVNALEITPD-RSMIAAAGYQHIRMYDLNsnNPNPVINYDGVSKNITSVGFHEDGR 98
           3899************************9.************8.5888888899********777777********************* PP
   S: 236  rlvsgssDgsiriWdlrsgdl 256
           ++++g++D   riWdlrs++l
   Q: 99   WMYTGGEDSMARIWDLRSRNL 119
           *****************9985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MNTSQGTVGS DPVILATAGY DHTVRFWQAH SGICTRTVQH QDSQVNALEI TPDRSMIAAA 60
GYQHIRMYDL NSNNPNPVIN YDGVSKNITS VGFHEDGRWM YTGGEDSMAR IWDLRSRNLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAATAAATG AGTCGGTTAG CAGGAAGAGA ATTAGAAAGA GGAGAAGATG GTGAAGGCAC 60
TATGATGGGA ATCAAGGGTA CACGAACGGG CAAGTATAAT GCCTGGTCTT TGGCTGGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031931--C:TORC1 complex
GO:0031932--C:TORC2 complex
GO:0043539--F:protein serine/threonine kinase activator activity
GO:0030838--P:positive regulation of actin filament polymerization
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0032008--P:positive regulation of TOR signaling
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity
GO:0031929--P:TOR signaling
GO:0038202--P:TORC1 signaling

KEGG

mdo:100011681

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000595	Aegilops tauschii	49.52	1.00e-85	309.00
IUUC-Aml-001813	Ailuropoda melanoleuca	94.79	0.00e+00	653.00
IUUC-Atr-002512	Amborella trichopoda	47.62	5.00e-81	294.00
IUUC-Apl-003495	Anas platyrhynchos	94.72	5.00e-159	553.00
IUUC-Aca-004613	Anolis carolinensis	97.24	0.00e+00	668.00
IUUC-Aly-006340	Arabidopsis lyrata	46.62	5.00e-81	294.00
IUUC-Ath-007273	Arabidopsis thaliana	46.30	2.00e-80	291.00
IUUC-Ago-007737	Ashbya gossypii	47.76	2.00e-83	301.00
IUUC-Acl-008090	Aspergillus clavatus	49.15	2.00e-60	226.00
IUUC-Afl-008490	Aspergillus flavus	43.37	8.00e-41	160.00
IUUC-Afu-009060	Aspergillus fumigatus	47.09	2.00e-53	202.00
IUUC-Ani-009251	Aspergillus nidulans	50.21	1.00e-60	226.00
IUUC-Ang-009528	Aspergillus niger	46.11	6.00e-77	280.00
IUUC-Aor-010005	Aspergillus oryzae	45.39	3.00e-70	258.00
IUUC-Ate-010423	Aspergillus terreus	49.58	9.00e-61	227.00
IUUC-Ame-011752	Astyanax mexicanus	95.09	0.00e+00	659.00
IUUC-Bgr-012299	Blumeria graminis	43.41	2.00e-72	266.00
IUUC-Bta-013007	Bos taurus	94.69	0.00e+00	643.00
IUUC-Bci-013987	Botrytis cinerea	44.62	1.00e-77	283.00
IUUC-Bdi-014082	Brachypodium distachyon	49.84	1.00e-85	309.00
IUUC-Bol-015088	Brassica oleracea	46.95	5.00e-81	293.00
IUUC-Bra-016682	Brassica rapa	40.72	1.00e-69	256.00
IUUC-Cel-018473	Caenorhabditis elegans	26.55	3.00e-38	152.00
IUUC-Cja-019216	Callithrix jacchus	94.01	2.00e-152	531.00
IUUC-Cfa-021229	Canis familiaris	95.09	0.00e+00	656.00
IUUC-Cpo-022270	Cavia porcellus	95.40	0.00e+00	658.00
IUUC-Cre-022742	Chlamydomonas reinhardtii	49.22	4.00e-87	314.00
IUUC-Csa-023275	Chlorocebus sabaeus	95.09	0.00e+00	655.00
IUUC-Cin-025588	Ciona intestinalis	63.81	4.00e-129	454.00
IUUC-Csv-026252	Ciona savignyi	64.98	5.00e-132	463.00
IUUC-Cgl-026418	Colletotrichum gloeosporioides	47.13	8.00e-78	283.00
IUUC-Cne-027013	Cryptococcus neoformans	43.45	5.00e-73	268.00
IUUC-Cme-027131	Cyanidioschyzon merolae	32.43	2.00e-51	196.00
IUUC-Dre-028424	Danio rerio	94.79	0.00e+00	658.00
IUUC-Dno-029327	Dasypus novemcinctus	95.09	0.00e+00	656.00
IUUC-Dor-030186	Dipodomys ordii	95.62	2.00e-90	325.00
IUUC-Dse-031475	Dothistroma septosporum	45.18	4.00e-76	278.00
IUUC-Dme-031826	Drosophila melanogaster	50.48	5.00e-96	344.00
IUUC-Ete-032252	Echinops telfairi	82.07	6.00e-137	479.00
IUUC-Eca-033889	Equus caballus	94.94	2.00e-135	474.00
IUUC-Fca-035989	Felis catus	94.79	0.00e+00	655.00
IUUC-Fal-036637	Ficedula albicollis	97.55	0.00e+00	671.00
IUUC-Fox-038066	Fusarium oxysporum	48.09	3.00e-81	294.00
IUUC-Fso-038288	Fusarium solani	45.86	2.00e-75	275.00
IUUC-Gmo-039477	Gadus morhua	93.58	0.00e+00	650.00
IUUC-Ggr-039990	Gaeumannomyces graminis	47.48	9.00e-78	283.00
IUUC-Gga-040890	Gallus gallus	97.55	0.00e+00	671.00
IUUC-Gac-041502	Gasterosteus aculeatus	94.79	0.00e+00	657.00
IUUC-Gma-042985	Glycine max	48.25	2.00e-82	298.00
IUUC-Ggo-045629	Gorilla gorilla	94.82	0.00e+00	653.00
IUUC-Hsa-045824	Homo sapiens	94.44	2.00e-165	574.00
IUUC-Hvu-047767	Hordeum vulgare	49.84	1.00e-85	309.00
IUUC-Itr-047932	Ictidomys tridecemlineatus	95.40	0.00e+00	658.00
IUUC-Kpa-049173	Komagataella pastoris	47.12	2.00e-83	302.00
IUUC-Lch-049703	Latimeria chalumnae	96.93	0.00e+00	667.00
IUUC-Lpe-050744	Leersia perrieri	45.40	6.00e-74	271.00
IUUC-Loc-052507	Lepisosteus oculatus	95.40	0.00e+00	659.00
IUUC-Lma-053084	Leptosphaeria maculans	45.29	1.00e-73	269.00
IUUC-Laf-053595	Loxodonta africana	95.40	0.00e+00	656.00
IUUC-Mcc-055634	Macaca mulatta	81.27	7.00e-179	619.00
IUUC-Meu-055925	Macropus eugenii	99.31	4.00e-173	600.00
IUUC-Mor-057131	Magnaporthe oryzae	44.48	4.00e-78	284.00
IUUC-Mpo-057524	Magnaporthe poae	47.80	2.00e-78	285.00
IUUC-Mtr-057980	Medicago truncatula	47.94	2.00e-82	298.00
IUUC-Mla-059082	Melampsora laricipopulina	40.17	1.00e-62	233.00
IUUC-Mga-059552	Meleagris gallopavo	95.41	5.00e-161	559.00
IUUC-Mvi-060504	Microbotryum violaceum	44.06	8.00e-71	261.00
IUUC-Mmu-063477	Mus musculus	94.48	0.00e+00	652.00
IUUC-Mac-065439	Musa acuminata	48.89	8.00e-84	303.00
IUUC-Mpu-066708	Mustela putorius furo	94.79	0.00e+00	652.00
IUUC-Mlu-067311	Myotis lucifugus	91.99	0.00e+00	643.00
IUUC-Nfi-068294	Neosartorya fischeri	46.90	7.00e-54	204.00
IUUC-Ncr-068811	Neurospora crassa	45.08	1.00e-75	276.00
IUUC-Nle-069632	Nomascus leucogenys	95.40	0.00e+00	657.00
IUUC-Opr-071128	Ochotona princeps	94.24	2.00e-106	377.00
IUUC-Ont-071494	Oreochromis niloticus	95.09	0.00e+00	660.00
IUUC-Oan-073298	Ornithorhynchus anatinus	93.12	3.00e-105	373.00
IUUC-Ocu-073983	Oryctolagus cuniculus	94.79	0.00e+00	652.00
IUUC-Oba-076001	Oryza barthii	44.76	3.00e-73	268.00
IUUC-Obr-076833	Oryza brachyantha	47.94	5.00e-82	297.00
IUUC-Ogl-077680	Oryza glaberrima	47.94	5.00e-82	297.00
IUUC-Ogu-078086	Oryza glumaepatula	44.76	4.00e-73	268.00
IUUC-Oin-079336	Oryza indica	47.94	5.00e-82	297.00
IUUC-Olo-080368	Oryza longistaminata	42.61	1.00e-59	223.00
IUUC-Oni-083046	Oryza nivara	44.76	2.00e-73	268.00
IUUC-Opu-084173	Oryza punctata	44.76	3.00e-73	268.00
IUUC-Oru-084599	Oryza rufipogon	44.76	3.00e-73	268.00
IUUC-Osa-086193	Oryza sativa	47.94	5.00e-82	297.00
IUUC-Ola-087216	Oryzias latipes	95.09	0.00e+00	660.00
IUUC-Olu-087852	Ostreococcus lucimarinus	47.94	3.00e-83	301.00
IUUC-Oga-088840	Otolemur garnettii	94.51	0.00e+00	651.00
IUUC-Oar-089294	Ovis aries	93.77	6.00e-165	572.00
IUUC-Ptr-090565	Pan troglodytes	95.40	0.00e+00	657.00
IUUC-Pan-092175	Papio anubis	95.09	0.00e+00	655.00
IUUC-Psi-093180	Pelodiscus sinensis	97.79	2.00e-161	560.00
IUUC-Pma-094705	Petromyzon marinus	84.36	4.00e-172	597.00
IUUC-Pno-095001	Phaeosphaeria nodorum	42.95	1.00e-63	236.00
IUUC-Ppa-095628	Physcomitrella patens	49.52	5.00e-86	310.00
IUUC-Pfo-097128	Poecilia formosa	94.79	0.00e+00	659.00
IUUC-Pab-098386	Pongo abelii	95.40	0.00e+00	657.00
IUUC-Pop-099064	Populus trichocarpa	48.57	5.00e-83	300.00
IUUC-Pca-100971	Procavia capensis	94.79	6.00e-167	579.00
IUUC-Ppe-101871	Prunus persica	48.57	6.00e-83	300.00
IUUC-Pva-102230	Pteropus vampyrus	75.17	2.00e-126	445.00
IUUC-Pgr-103511	Puccinia graminis	41.57	4.00e-66	244.00
IUUC-Ptt-103882	Puccinia triticina	37.77	4.00e-63	235.00
IUUC-Pte-104402	Pyrenophora teres	45.90	9.00e-75	273.00
IUUC-Pyt-104448	Pyrenophora triticirepentis	45.90	9.00e-75	273.00
IUUC-Rno-104880	Rattus norvegicus	94.48	0.00e+00	654.00
IUUC-Sce-106266	Saccharomyces cerevisiae	48.08	9.00e-85	306.00
IUUC-Sha-106966	Sarcophilus harrisii	100.00	0.00e+00	684.00
IUUC-Sja-107797	Schizosaccharomyces japonicus	47.59	1.00e-85	309.00
IUUC-Spo-108366	Schizosaccharomyces pombe	46.30	4.00e-85	307.00
IUUC-Smo-108749	Selaginella moellendorffii	48.10	4.00e-81	294.00
IUUC-Sit-110807	Setaria italica	49.84	5.00e-85	307.00
IUUC-Sly-111879	Solanum lycopersicum	43.28	2.00e-50	192.00
IUUC-Sbi-114551	Sorghum bicolor	49.84	7.00e-85	306.00
IUUC-Sre-114962	Sporisorium reilianum	39.67	1.00e-74	273.00
IUUC-Ssc-115363	Sus scrofa	94.51	0.00e+00	652.00
IUUC-Tgu-116695	Taeniopygia guttata	79.75	6.00e-148	516.00
IUUC-Tru-117999	Takifugu rubripes	93.60	0.00e+00	652.00
IUUC-Tni-119973	Tetraodon nigroviridis	94.17	0.00e+00	658.00
IUUC-Tca-121688	Theobroma cacao	48.10	3.00e-82	298.00
IUUC-Tre-122158	Trichoderma reesei	43.81	5.00e-76	277.00
IUUC-Tvi-122511	Trichoderma virens	46.08	2.00e-77	282.00
IUUC-Tae-124124	Triticum aestivum	49.52	1.00e-85	309.00
IUUC-Tur-126228	Triticum urartu	46.67	8.00e-77	280.00
IUUC-Tme-127100	Tuber melanosporum	49.20	1.00e-87	315.00
IUUC-Ttr-128216	Tursiops truncatus	94.85	2.00e-52	199.00
IUUC-Uma-129358	Ustilago maydis	40.34	2.00e-75	276.00
IUUC-Vda-129756	Verticillium dahliae	46.35	1.00e-78	286.00
IUUC-Vvi-131581	Vitis vinifera	46.67	5.00e-80	291.00
IUUC-Xtr-132363	Xenopus tropicalis	93.56	0.00e+00	649.00
IUUC-Xma-133857	Xiphophorus maculatus	94.79	0.00e+00	659.00
IUUC-Yli-134368	Yarrowia lipolytica	47.12	2.00e-81	295.00
IUUC-Zma-135854	Zea mays	49.84	5.00e-85	307.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence