iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053810

Ensembl Protein ID

ENSLAFP00000005220.3

UniProt Accession

G3SXS3; G3SXS3_LOXAF

Protein Name

DNA repair protein REV1

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000006217.3	ENSLAFT00000006219.3	ENSLAFP00000005220.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	2.00e-20	72.1	1019	1045

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 3    sqvDpeVfsqLPeeiQeEvmaelrqqk 29
           sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1019 SQVDPEVFAALPAELQKELRAAYDQRQ 1045
           8************************98 PP

Organism

Loxodonta africana

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRA ENDGWQKWGG YMAAKVRKLE EQFRSDATVQ KEGDSSTIFS GVAIYVNGYT 60
GDPSAEELRR LMMSHGGQYR VYYSRSKTTH IIATNLPNAK INELRGKAIW PEFIFTWLVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCGAG GTGGATGGAG GAAACGAGCT GAAAATGATG GCTGGCAAAA ATGGGTGTGT 60
TTTAAAAGAA TAAAATTAAT TGTGTTGAAC TTTCTAGATA TTTTTCATTC TTATTTTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	29.49	9.00e-32	132.00
IUUC-Aml-001185	Ailuropoda melanoleuca	83.41	0.00e+00	2013.00
IUUC-Atr-002915	Amborella trichopoda	33.06	5.00e-86	313.00
IUUC-Apl-004054	Anas platyrhynchos	73.08	0.00e+00	1723.00
IUUC-Aca-004304	Anolis carolinensis	67.35	0.00e+00	1607.00
IUUC-Aly-005696	Arabidopsis lyrata	34.03	2.00e-83	303.00
IUUC-Ath-006893	Arabidopsis thaliana	33.91	8.00e-84	305.00
IUUC-Ago-007722	Ashbya gossypii	29.14	1.00e-40	161.00
IUUC-Acl-008347	Aspergillus clavatus	35.26	2.00e-87	317.00
IUUC-Afl-008444	Aspergillus flavus	36.77	3.00e-87	317.00
IUUC-Afu-008837	Aspergillus fumigatus	27.96	4.00e-86	313.00
IUUC-Ani-009188	Aspergillus nidulans	37.27	3.00e-90	326.00
IUUC-Ang-009866	Aspergillus niger	33.15	8.00e-98	352.00
IUUC-Aor-010107	Aspergillus oryzae	36.77	3.00e-87	316.00
IUUC-Ate-010359	Aspergillus terreus	36.57	1.00e-89	325.00
IUUC-Ame-010664	Astyanax mexicanus	54.20	0.00e+00	894.00
IUUC-Bgr-012244	Blumeria graminis	28.53	4.00e-81	296.00
IUUC-Bta-013405	Bos taurus	79.17	0.00e+00	1740.00
IUUC-Bci-013849	Botrytis cinerea	31.51	3.00e-89	323.00
IUUC-Bdi-014066	Brachypodium distachyon	36.73	4.00e-85	310.00
IUUC-Bol-015544	Brassica oleracea	35.15	2.00e-86	313.00
IUUC-Bra-017792	Brassica rapa	34.05	6.00e-81	295.00
IUUC-Cel-018148	Caenorhabditis elegans	35.60	7.00e-82	298.00
IUUC-Cja-019742	Callithrix jacchus	70.74	0.00e+00	1398.00
IUUC-Cfa-020112	Canis familiaris	84.44	0.00e+00	2033.00
IUUC-Cpo-022152	Cavia porcellus	79.68	0.00e+00	1962.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	43.95	3.00e-39	157.00
IUUC-Csa-023504	Chlorocebus sabaeus	82.14	0.00e+00	1999.00
IUUC-Cho-024780	Choloepus hoffmanni	80.13	0.00e+00	688.00
IUUC-Cin-025276	Ciona intestinalis	43.07	4.00e-113	402.00
IUUC-Csv-026283	Ciona savignyi	44.54	2.00e-114	406.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	28.57	7.00e-91	328.00
IUUC-Cne-027079	Cryptococcus neoformans	34.25	8.00e-78	285.00
IUUC-Cme-027346	Cyanidioschyzon merolae	28.36	2.00e-46	181.00
IUUC-Dre-028073	Danio rerio	49.77	0.00e+00	1082.00
IUUC-Dno-030038	Dasypus novemcinctus	81.02	0.00e+00	1959.00
IUUC-Dor-031100	Dipodomys ordii	79.36	0.00e+00	1449.00
IUUC-Dse-031310	Dothistroma septosporum	28.87	7.00e-85	308.00
IUUC-Dme-031991	Drosophila melanogaster	41.34	1.00e-108	387.00
IUUC-Ete-033082	Echinops telfairi	77.43	0.00e+00	1424.00
IUUC-Eca-033471	Equus caballus	84.52	0.00e+00	2038.00
IUUC-Eeu-034993	Erinaceus europaeus	79.98	0.00e+00	1323.00
IUUC-Fca-035367	Felis catus	84.40	0.00e+00	1960.00
IUUC-Fal-036973	Ficedula albicollis	72.36	0.00e+00	1667.00
IUUC-Fox-037677	Fusarium oxysporum	31.62	9.00e-87	315.00
IUUC-Fso-038252	Fusarium solani	31.86	3.00e-92	333.00
IUUC-Gmo-039669	Gadus morhua	59.88	5.00e-170	592.00
IUUC-Ggr-039988	Gaeumannomyces graminis	30.66	2.00e-84	308.00
IUUC-Gga-040423	Gallus gallus	73.39	0.00e+00	1716.00
IUUC-Gac-042134	Gasterosteus aculeatus	47.63	0.00e+00	955.00
IUUC-Gma-042929	Glycine max	37.42	4.00e-87	316.00
IUUC-Ggo-044528	Gorilla gorilla	82.46	0.00e+00	2009.00
IUUC-Hsa-046259	Homo sapiens	82.30	0.00e+00	1978.00
IUUC-Hvu-047139	Hordeum vulgare	36.62	1.00e-57	217.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	82.38	0.00e+00	2010.00
IUUC-Kpa-049169	Komagataella pastoris	30.69	8.00e-62	232.00
IUUC-Lch-050471	Latimeria chalumnae	63.54	0.00e+00	1462.00
IUUC-Lpe-050800	Leersia perrieri	32.80	7.00e-87	315.00
IUUC-Loc-052320	Lepisosteus oculatus	46.33	0.00e+00	886.00
IUUC-Lma-053149	Leptosphaeria maculans	29.84	1.00e-87	318.00
IUUC-Mcc-055574	Macaca mulatta	82.38	0.00e+00	1972.00
IUUC-Meu-055945	Macropus eugenii	66.38	0.00e+00	1018.00
IUUC-Mor-057195	Magnaporthe oryzae	30.51	2.00e-89	324.00
IUUC-Mpo-057488	Magnaporthe poae	34.94	3.00e-84	307.00
IUUC-Mtr-057955	Medicago truncatula	35.25	6.00e-87	315.00
IUUC-Mla-059027	Melampsora laricipopulina	36.38	1.00e-78	287.00
IUUC-Mga-060156	Meleagris gallopavo	73.23	0.00e+00	1736.00
IUUC-Mvi-060398	Microbotryum violaceum	35.52	3.00e-80	293.00
IUUC-Mmr-061113	Microcebus murinus	83.41	0.00e+00	2000.00
IUUC-Mdo-063001	Monodelphis domestica	78.99	0.00e+00	1887.00
IUUC-Mmu-063180	Mus musculus	77.97	0.00e+00	1860.00
IUUC-Mac-065551	Musa acuminata	36.60	7.00e-52	198.00
IUUC-Mpu-066525	Mustela putorius furo	83.89	0.00e+00	2016.00
IUUC-Mlu-067877	Myotis lucifugus	82.94	0.00e+00	1955.00
IUUC-Nfi-068418	Neosartorya fischeri	31.38	8.00e-87	315.00
IUUC-Ncr-068648	Neurospora crassa	31.48	4.00e-86	313.00
IUUC-Nle-069959	Nomascus leucogenys	82.54	0.00e+00	1986.00
IUUC-Opr-070522	Ochotona princeps	77.50	0.00e+00	1098.00
IUUC-Ont-072293	Oreochromis niloticus	46.62	0.00e+00	809.00
IUUC-Oan-073519	Ornithorhynchus anatinus	76.63	0.00e+00	1826.00
IUUC-Ocu-074492	Oryctolagus cuniculus	78.85	0.00e+00	1803.00
IUUC-Oba-075567	Oryza barthii	29.94	6.00e-108	385.00
IUUC-Obr-076332	Oryza brachyantha	36.46	7.00e-86	312.00
IUUC-Ogl-077348	Oryza glaberrima	29.39	7.00e-104	372.00
IUUC-Ogu-078779	Oryza glumaepatula	30.45	1.00e-107	384.00
IUUC-Oin-079738	Oryza indica	31.29	9.00e-78	285.00
IUUC-Olo-080701	Oryza longistaminata	31.29	5.00e-78	286.00
IUUC-Ome-081708	Oryza meridionalis	33.55	3.00e-88	320.00
IUUC-Oni-082251	Oryza nivara	30.35	1.00e-105	377.00
IUUC-Opu-083528	Oryza punctata	29.84	3.00e-102	366.00
IUUC-Oru-084293	Oryza rufipogon	30.04	2.00e-103	370.00
IUUC-Osa-085549	Oryza sativa	30.01	1.00e-103	371.00
IUUC-Ola-086793	Oryzias latipes	45.99	0.00e+00	961.00
IUUC-Olu-087786	Ostreococcus lucimarinus	28.60	5.00e-61	228.00
IUUC-Oga-089006	Otolemur garnettii	82.67	0.00e+00	1988.00
IUUC-Oar-089597	Ovis aries	79.92	0.00e+00	1915.00
IUUC-Ptr-091520	Pan troglodytes	82.38	0.00e+00	1979.00
IUUC-Pan-092333	Papio anubis	82.46	0.00e+00	1957.00
IUUC-Psi-094004	Pelodiscus sinensis	74.98	0.00e+00	1783.00
IUUC-Pma-094128	Petromyzon marinus	52.27	2.00e-90	326.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.40	5.00e-82	299.00
IUUC-Ppa-095714	Physcomitrella patens	31.62	3.00e-92	333.00
IUUC-Pfo-096569	Poecilia formosa	52.29	0.00e+00	806.00
IUUC-Pab-097960	Pongo abelii	82.06	0.00e+00	1972.00
IUUC-Pop-098921	Populus trichocarpa	36.79	4.00e-84	306.00
IUUC-Pca-100509	Procavia capensis	67.27	0.00e+00	1156.00
IUUC-Ppe-101730	Prunus persica	36.00	3.00e-87	316.00
IUUC-Pva-102142	Pteropus vampyrus	82.22	0.00e+00	1972.00
IUUC-Pgr-103446	Puccinia graminis	30.08	2.00e-64	241.00
IUUC-Ptt-103849	Puccinia triticina	29.93	1.00e-69	258.00
IUUC-Pte-104128	Pyrenophora teres	31.06	1.00e-84	308.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	34.61	1.00e-82	301.00
IUUC-Rno-104871	Rattus norvegicus	75.99	0.00e+00	1817.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.80	3.00e-39	157.00
IUUC-Sha-106962	Sarcophilus harrisii	78.17	0.00e+00	1864.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	29.23	9.00e-67	248.00
IUUC-Spo-108170	Schizosaccharomyces pombe	34.81	2.00e-64	241.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	28.06	4.00e-98	353.00
IUUC-Smo-109554	Selaginella moellendorffii	36.85	6.00e-85	309.00
IUUC-Sit-110479	Setaria italica	36.02	8.00e-73	268.00
IUUC-Sly-111752	Solanum lycopersicum	31.60	5.00e-88	319.00
IUUC-Sar-113304	Sorex araneus	80.95	0.00e+00	1896.00
IUUC-Sbi-114196	Sorghum bicolor	36.69	1.00e-74	275.00
IUUC-Sre-115151	Sporisorium reilianum	32.41	7.00e-84	306.00
IUUC-Ssc-116104	Sus scrofa	82.41	0.00e+00	1956.00
IUUC-Tgu-117438	Taeniopygia guttata	73.70	0.00e+00	1711.00
IUUC-Tru-118553	Takifugu rubripes	47.31	0.00e+00	956.00
IUUC-Tsy-119056	Tarsius syrichta	78.29	0.00e+00	1819.00
IUUC-Tni-119933	Tetraodon nigroviridis	46.69	0.00e+00	758.00
IUUC-Tca-121376	Theobroma cacao	35.80	7.00e-85	309.00
IUUC-Tre-121972	Trichoderma reesei	28.34	7.00e-84	305.00
IUUC-Tvi-122342	Trichoderma virens	28.83	3.00e-94	340.00
IUUC-Tae-123898	Triticum aestivum	33.76	1.00e-89	324.00
IUUC-Tur-126735	Triticum urartu	29.64	1.00e-35	145.00
IUUC-Tme-126999	Tuber melanosporum	33.47	3.00e-80	294.00
IUUC-Tbe-127280	Tupaia belangeri	85.13	3.00e-132	466.00
IUUC-Ttr-129104	Tursiops truncatus	81.44	0.00e+00	1930.00
IUUC-Uma-129562	Ustilago maydis	30.45	3.00e-85	310.00
IUUC-Vda-129862	Verticillium dahliae	30.64	3.00e-88	320.00
IUUC-Vpa-130819	Vicugna pacos	79.69	0.00e+00	1012.00
IUUC-Vvi-131111	Vitis vinifera	35.62	5.00e-85	309.00
IUUC-Xtr-132629	Xenopus tropicalis	60.47	0.00e+00	1352.00
IUUC-Xma-134065	Xiphophorus maculatus	51.98	0.00e+00	796.00
IUUC-Yli-134633	Yarrowia lipolytica	33.60	9.00e-63	235.00
IUUC-Zma-135176	Zea mays	33.44	6.00e-88	318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence