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Tag Content
iUUCD ID IUUC-Ocu-074492
Ensembl Protein ID ENSOCUP00000012536.3
UniProt Accession G1T7P6; G1T7P6_RABIT
Genbank Protein ID ENSOCUP00000012536
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AAGW02007486
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000014576.3 ENSOCUT00000014583.3 ENSOCUP00000012536.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 8.90e-23 79.2 932 960
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           +Psq+D++V+++LP++++e+v++++++q+
   Q: 932  SPSQLDQSVLEALPPDLREQVEHACAIQQ 960
           7***************************8 PP
   
Organism Oryctolagus cuniculus
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRGGWRKRA ENDGWEKWGG YMAAKVQKLE EQFRSDAAMQ KDGTSSSIFS GVAIYVNGFT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
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Protein Fasta Sequence


>IUUC-Ocu-074492|UBD,UBM|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTCCTGTT TGAAATTTAT AATTTAAACA TTGTGCTTAC ATAGGAGAAT GTTTTAGGAA 60
CAAATTTTAC TTGTAAAGAA TGGGAATGTT ACTTTCTGGA AAAAAGTTTA CTGTACTTTT 120
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Nucleotide Fasta Sequence


>IUUC-Ocu-074492|UBD,UBM|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR012112--REV1
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 31.96 1.00e-31 132.00
IUUC-Aml-001185 Ailuropoda melanoleuca 83.15 0.00e+00 1909.00
IUUC-Atr-002915 Amborella trichopoda 30.77 8.00e-105 375.00
IUUC-Apl-004054 Anas platyrhynchos 73.58 0.00e+00 1665.00
IUUC-Aca-004304 Anolis carolinensis 66.22 0.00e+00 1518.00
IUUC-Aly-005696 Arabidopsis lyrata 35.79 5.00e-85 309.00
IUUC-Ath-006893 Arabidopsis thaliana 35.87 3.00e-86 313.00
IUUC-Ago-007722 Ashbya gossypii 28.57 5.00e-40 159.00
IUUC-Acl-008347 Aspergillus clavatus 38.01 8.00e-87 315.00
IUUC-Afl-008444 Aspergillus flavus 36.77 2.00e-86 314.00
IUUC-Afu-008837 Aspergillus fumigatus 31.38 8.00e-87 315.00
IUUC-Ani-009188 Aspergillus nidulans 37.90 5.00e-93 336.00
IUUC-Ang-009866 Aspergillus niger 34.14 8.00e-100 358.00
IUUC-Aor-010107 Aspergillus oryzae 36.77 2.00e-86 313.00
IUUC-Ate-010359 Aspergillus terreus 32.64 5.00e-92 332.00
IUUC-Ame-010664 Astyanax mexicanus 47.01 0.00e+00 997.00
IUUC-Bgr-012244 Blumeria graminis 32.53 7.00e-80 292.00
IUUC-Bta-013405 Bos taurus 78.20 0.00e+00 1640.00
IUUC-Bci-013849 Botrytis cinerea 31.36 5.00e-91 329.00
IUUC-Bdi-014066 Brachypodium distachyon 38.03 1.00e-88 321.00
IUUC-Bol-015544 Brassica oleracea 36.96 9.00e-88 318.00
IUUC-Bra-017792 Brassica rapa 35.20 2.00e-84 307.00
IUUC-Cel-018148 Caenorhabditis elegans 36.08 4.00e-83 302.00
IUUC-Cja-019742 Callithrix jacchus 73.43 0.00e+00 1424.00
IUUC-Cfa-020112 Canis familiaris 84.02 0.00e+00 1930.00
IUUC-Cpo-022152 Cavia porcellus 81.71 0.00e+00 1946.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 43.95 1.00e-38 155.00
IUUC-Csa-023504 Chlorocebus sabaeus 84.86 0.00e+00 1977.00
IUUC-Cho-024780 Choloepus hoffmanni 67.50 0.00e+00 731.00
IUUC-Cin-025276 Ciona intestinalis 51.74 1.00e-100 360.00
IUUC-Csv-026283 Ciona savignyi 44.40 7.00e-113 401.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 30.71 8.00e-90 325.00
IUUC-Cne-027079 Cryptococcus neoformans 34.19 2.00e-77 284.00
IUUC-Cme-027346 Cyanidioschyzon merolae 28.63 2.00e-46 181.00
IUUC-Dre-028073 Danio rerio 48.07 0.00e+00 965.00
IUUC-Dno-030038 Dasypus novemcinctus 80.20 0.00e+00 1853.00
IUUC-Dor-031100 Dipodomys ordii 77.47 0.00e+00 1315.00
IUUC-Dse-031310 Dothistroma septosporum 31.67 5.00e-84 306.00
IUUC-Dme-031991 Drosophila melanogaster 42.68 3.00e-112 399.00
IUUC-Ete-033082 Echinops telfairi 73.61 0.00e+00 1247.00
IUUC-Eca-033471 Equus caballus 83.77 0.00e+00 1924.00
IUUC-Eeu-034993 Erinaceus europaeus 82.19 0.00e+00 1350.00
IUUC-Fca-035367 Felis catus 82.93 0.00e+00 1830.00
IUUC-Fal-036973 Ficedula albicollis 73.48 0.00e+00 1595.00
IUUC-Fox-037677 Fusarium oxysporum 31.10 2.00e-90 327.00
IUUC-Fso-038252 Fusarium solani 30.87 3.00e-92 333.00
IUUC-Gmo-039669 Gadus morhua 50.59 0.00e+00 739.00
IUUC-Ggr-039988 Gaeumannomyces graminis 35.20 3.00e-85 310.00
IUUC-Gga-040423 Gallus gallus 73.24 0.00e+00 1642.00
IUUC-Gac-042134 Gasterosteus aculeatus 47.67 0.00e+00 719.00
IUUC-Gma-042929 Glycine max 33.01 1.00e-115 411.00
IUUC-Ggo-044528 Gorilla gorilla 85.12 0.00e+00 1951.00
IUUC-Hsa-046259 Homo sapiens 84.95 0.00e+00 1920.00
IUUC-Hvu-047139 Hordeum vulgare 37.37 2.00e-61 229.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 84.49 0.00e+00 1966.00
IUUC-Kpa-049169 Komagataella pastoris 29.94 6.00e-61 229.00
IUUC-Lch-050471 Latimeria chalumnae 62.55 0.00e+00 1402.00
IUUC-Lpe-050800 Leersia perrieri 34.84 6.00e-91 329.00
IUUC-Loc-052320 Lepisosteus oculatus 44.49 0.00e+00 816.00
IUUC-Lma-053149 Leptosphaeria maculans 29.93 5.00e-85 309.00
IUUC-Laf-053810 Loxodonta africana 78.85 0.00e+00 1748.00
IUUC-Mcc-055574 Macaca mulatta 85.12 0.00e+00 1920.00
IUUC-Meu-055945 Macropus eugenii 63.14 0.00e+00 1100.00
IUUC-Mor-057195 Magnaporthe oryzae 30.86 2.00e-92 334.00
IUUC-Mpo-057488 Magnaporthe poae 34.93 1.00e-85 311.00
IUUC-Mtr-057955 Medicago truncatula 36.58 5.00e-93 335.00
IUUC-Mla-059027 Melampsora laricipopulina 34.64 8.00e-79 288.00
IUUC-Mga-060156 Meleagris gallopavo 73.24 0.00e+00 1648.00
IUUC-Mvi-060398 Microbotryum violaceum 34.92 1.00e-79 291.00
IUUC-Mmr-061113 Microcebus murinus 85.63 0.00e+00 1947.00
IUUC-Mdo-063001 Monodelphis domestica 78.52 0.00e+00 1791.00
IUUC-Mmu-063180 Mus musculus 80.07 0.00e+00 1832.00
IUUC-Mac-065551 Musa acuminata 37.27 2.00e-55 210.00
IUUC-Mpu-066525 Mustela putorius furo 83.18 0.00e+00 1893.00
IUUC-Mlu-067877 Myotis lucifugus 82.76 0.00e+00 1871.00
IUUC-Nfi-068418 Neosartorya fischeri 32.06 6.00e-88 319.00
IUUC-Ncr-068648 Neurospora crassa 32.14 8.00e-90 325.00
IUUC-Nle-069959 Nomascus leucogenys 85.12 0.00e+00 1934.00
IUUC-Opr-070522 Ochotona princeps 85.18 0.00e+00 1198.00
IUUC-Ont-072293 Oreochromis niloticus 46.81 0.00e+00 737.00
IUUC-Oan-073519 Ornithorhynchus anatinus 75.73 0.00e+00 1738.00
IUUC-Oba-075567 Oryza barthii 34.53 3.00e-94 340.00
IUUC-Obr-076332 Oryza brachyantha 38.68 1.00e-90 328.00
IUUC-Ogl-077348 Oryza glaberrima 34.53 4.00e-94 339.00
IUUC-Ogu-078779 Oryza glumaepatula 34.37 7.00e-94 338.00
IUUC-Oin-079738 Oryza indica 31.84 3.00e-82 300.00
IUUC-Olo-080701 Oryza longistaminata 31.84 2.00e-82 300.00
IUUC-Ome-081708 Oryza meridionalis 34.68 7.00e-90 325.00
IUUC-Oni-082251 Oryza nivara 34.21 2.00e-91 330.00
IUUC-Opu-083528 Oryza punctata 33.85 4.00e-85 310.00
IUUC-Oru-084293 Oryza rufipogon 33.75 6.00e-89 322.00
IUUC-Osa-085549 Oryza sativa 34.53 7.00e-94 338.00
IUUC-Ola-086793 Oryzias latipes 46.66 0.00e+00 742.00
IUUC-Olu-087786 Ostreococcus lucimarinus 28.81 6.00e-62 231.00
IUUC-Oga-089006 Otolemur garnettii 84.06 0.00e+00 1924.00
IUUC-Oar-089597 Ovis aries 79.04 0.00e+00 1799.00
IUUC-Ptr-091520 Pan troglodytes 84.95 0.00e+00 1919.00
IUUC-Pan-092333 Papio anubis 85.12 0.00e+00 1902.00
IUUC-Psi-094004 Pelodiscus sinensis 74.15 0.00e+00 1696.00
IUUC-Pma-094128 Petromyzon marinus 55.02 4.00e-95 342.00
IUUC-Pno-094849 Phaeosphaeria nodorum 29.09 6.00e-80 292.00
IUUC-Ppa-095714 Physcomitrella patens 31.77 2.00e-93 337.00
IUUC-Pfo-096569 Poecilia formosa 45.76 0.00e+00 922.00
IUUC-Pab-097960 Pongo abelii 84.70 0.00e+00 1913.00
IUUC-Pop-098921 Populus trichocarpa 36.42 5.00e-84 306.00
IUUC-Pca-100509 Procavia capensis 66.35 0.00e+00 1111.00
IUUC-Ppe-101730 Prunus persica 37.86 5.00e-93 336.00
IUUC-Pva-102142 Pteropus vampyrus 80.96 0.00e+00 1852.00
IUUC-Pgr-103446 Puccinia graminis 30.61 7.00e-70 258.00
IUUC-Ptt-103849 Puccinia triticina 29.43 2.00e-71 265.00
IUUC-Pte-104128 Pyrenophora teres 30.38 2.00e-87 317.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 31.88 5.00e-82 299.00
IUUC-Rno-104871 Rattus norvegicus 77.87 0.00e+00 1805.00
IUUC-Sce-106236 Saccharomyces cerevisiae 26.48 2.00e-39 157.00
IUUC-Sha-106962 Sarcophilus harrisii 77.53 0.00e+00 1787.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 28.20 4.00e-65 243.00
IUUC-Spo-108170 Schizosaccharomyces pombe 30.40 1.00e-66 248.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 34.86 5.00e-87 316.00
IUUC-Smo-109554 Selaginella moellendorffii 37.34 2.00e-87 317.00
IUUC-Sit-110479 Setaria italica 37.36 2.00e-74 274.00
IUUC-Sly-111752 Solanum lycopersicum 37.80 2.00e-92 333.00
IUUC-Sar-113304 Sorex araneus 82.06 0.00e+00 1815.00
IUUC-Sbi-114196 Sorghum bicolor 43.83 1.00e-73 271.00
IUUC-Sre-115151 Sporisorium reilianum 31.94 5.00e-82 300.00
IUUC-Ssc-116104 Sus scrofa 82.77 0.00e+00 1874.00
IUUC-Tgu-117438 Taeniopygia guttata 74.00 0.00e+00 1632.00
IUUC-Tru-118553 Takifugu rubripes 45.77 0.00e+00 899.00
IUUC-Tsy-119056 Tarsius syrichta 81.08 0.00e+00 1793.00
IUUC-Tni-119933 Tetraodon nigroviridis 44.70 0.00e+00 878.00
IUUC-Tca-121376 Theobroma cacao 35.47 8.00e-87 315.00
IUUC-Tre-121972 Trichoderma reesei 34.73 6.00e-81 296.00
IUUC-Tvi-122342 Trichoderma virens 31.31 4.00e-82 299.00
IUUC-Tae-123898 Triticum aestivum 33.96 5.00e-93 335.00
IUUC-Tur-126735 Triticum urartu 31.14 2.00e-35 145.00
IUUC-Tme-126999 Tuber melanosporum 32.67 6.00e-80 293.00
IUUC-Tbe-127280 Tupaia belangeri 77.05 3.00e-93 337.00
IUUC-Ttr-129104 Tursiops truncatus 81.59 0.00e+00 1817.00
IUUC-Uma-129562 Ustilago maydis 29.45 8.00e-83 302.00
IUUC-Vda-129862 Verticillium dahliae 31.81 1.00e-92 334.00
IUUC-Vpa-130819 Vicugna pacos 81.69 0.00e+00 1059.00
IUUC-Vvi-131111 Vitis vinifera 35.43 2.00e-87 317.00
IUUC-Xtr-132629 Xenopus tropicalis 59.18 0.00e+00 1273.00
IUUC-Xma-134065 Xiphophorus maculatus 43.43 0.00e+00 725.00
IUUC-Yli-134633 Yarrowia lipolytica 32.82 3.00e-63 237.00
IUUC-Zma-135176 Zea mays 37.67 7.00e-91 328.00
Created Date 25-Jun-2017

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