iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125702

Ensembl Protein ID

TRIAE_CS42_2BS_TGACv1_148276_AA0491870.1

UniProt Accession

W5BJQ0; W5BJQ0_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_2BS_TGACv1_148276_AA0491870	TRIAE_CS42_2BS_TGACv1_148276_AA0491870.1	TRIAE_CS42_2BS_TGACv1_148276_AA0491870.1
TRIAE_CS42_2BS_TGACv1_148276_AA0491870	TRIAE_CS42_2BS_TGACv1_148276_AA0491870.2	TRIAE_CS42_2BS_TGACv1_148276_AA0491870.2
TRIAE_CS42_2BS_TGACv1_148276_AA0491870	TRIAE_CS42_2BS_TGACv1_148276_AA0491870.3	TRIAE_CS42_2BS_TGACv1_148276_AA0491870.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.20e-168	564.3	445	932

Active Site

Position(s)	Description	Evidence
626	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLf 64
           YD Q+ ++G++ q+k+++a+ ++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLf
   Q: 445  YDAQVSVFGSKLQKKMEEANTFVVGSGALGCEFLKNLALMGVscsskGKLTITDDDIIEKSNLSRQFLF 513
           ********************************************************************* PP
   S: 65   raedvgksKAevaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlc 130
           r++++g+ K+ vaa a+  +np+ +++a +++ ++++e+++   F + +dvV++aldn+ ar++++ +c
   Q: 514  RDWNIGQAKSTVAATAASAINPSLHIDALQNRACPDTENVFhdtFWEGLDVVINALDNVNARMYMDMRC 582
           ***************************************8899999999******************** PP
   S: 131  lnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa......... 190
           l+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa         
   Q: 583  LYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsefeglle 651
           ********************************************************************* PP
   S: 191  ...vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikql 256
                +n +l++ a+      k   ++ +e +++v++ l++ + ++f+++i++a+ +f+ +++n +kql
   Q: 652  ktpNEVNSFLSNPAQYAAAMRKAGDAQARELLERVSECLNKDRCSTFDDCISWARLKFEDYFSNRVKQL 720
           **99999999999999999999*********************************************** PP
   S: 257  lksfecdivtkskspfwv................................................... 274
           +  f+ d  t+ ++pfw+                                                   
   Q: 721  TFTFPEDAATSMGAPFWSapkrfpralqfsaadqshlnfimsasilraesfgvaipewakdtskladvv 789
           ************************999999999999999999999999999999999999999777777 PP
   S: 275  ...sfcsnaealqvpekvekdeevvkasap.....lylllralerfekk..kgrkpgelsfekddds.. 331
               +++++ ++ v+  ++++  ++++++      ++ ll++l++ +k   +g +++ ++fekddds  
   Q: 790  kkiAVPTFEPKQGVNIVTDEKASNLSSTSVddvavIEDLLAKLQEYAKGlpPGFQMKPIQFEKDDDSnf 858
           77644444444444444444444443333355667888999999999975589**************** PP
   S: 332  avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknf 398
           ++dl+  +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  + e ++n+
   Q: 859  HMDLISGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVIAGehPVEDYRNT 926
           ********************.*************************************9999999**** PP
   S: 399  flfdae 404
           f ++a+
   Q: 927  FANLAL 932
           *99875 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MLPSKRPSDA AAGDENGRGG DAKRPRLGET EGGGSNGAAP QEIDEDLHSR QLAVYGRETM 60
RRLFASDVLV SGLNGLGAEI AKNLALAGVK SVTIHDVKNV EMWDLSGNFF LSEDDIGKNR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGATTCAA AAACAAAATT TGTCATCGAG TTCGTATTTT GAAATCTTGT ACAACCACAG 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004158	Anas platyrhynchos	39.51	0.00e+00	685.00
IUUC-Bdi-014009	Brachypodium distachyon	87.86	0.00e+00	1824.00
IUUC-Cel-018260	Caenorhabditis elegans	38.40	0.00e+00	656.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.89	0.00e+00	697.00
IUUC-Dse-031524	Dothistroma septosporum	43.50	0.00e+00	834.00
IUUC-Fal-036848	Ficedula albicollis	39.03	0.00e+00	691.00
IUUC-Gga-040747	Gallus gallus	39.41	0.00e+00	686.00
IUUC-Hvu-047191	Hordeum vulgare	98.28	0.00e+00	2002.00
IUUC-Lpe-051299	Leersia perrieri	86.37	0.00e+00	1846.00
IUUC-Mga-059721	Meleagris gallopavo	39.80	0.00e+00	662.00
IUUC-Obr-076244	Oryza brachyantha	87.24	0.00e+00	1783.00
IUUC-Psi-093489	Pelodiscus sinensis	38.75	0.00e+00	689.00
IUUC-Sit-110294	Setaria italica	85.69	0.00e+00	1881.00
IUUC-Sbi-114774	Sorghum bicolor	86.33	0.00e+00	1903.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence