iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.6__1618__AT5G16310.1	fgenesh2_kg.6__1618__AT5G16310.1	fgenesh2_kg.6__1618__AT5G16310.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	8.40e-71	239.7	2	329

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
163	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvded 83
           +wl++esdPg+ft+++++  vk++ qveelysLd ++l+ + +pv+gl+ll+k+ ++++++r          vv  +
   Q: 2    SWLPVESDPGIFTEIIQQMQVKGV-QVEELYSLDFNSLDEI-RPVYGLILLYKWRPEEKENR----------VVITE 66
           7***********************.***************9.***************99998..........44456 PP
   S: 84   iiktiffakqvigNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesr 160
              + ffa q i+N+Cat+A+lsvl n ++   d+G++ls+lk++ k + pe k+la++n+++++++hn++ar++++
   Q: 67   PNPNFFFASQIINNACATQAILSVLMNSSSI--DIGSELSELKQFAKEFPPELKGLAISNNEAIRAAHNTFARSDPS 141
           678************************9998..******************************************99 PP
   S: 161  seperqdedneqy...tkeafhfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvr.aflerikllesde 233
           s  e+++   ++    +++++h++sy +++g lyeldglk+ P+ lg++  + e ++ l+ v+    eri+ ++++e
   Q: 142  STMEEEELAAAKNldeDDDVYHYISYLPVDGILYELDGLKEGPISLGQCLGEPEGTEWLRMVQpVVQERIDWYSQNE 218
           8877765444444566999******************************877777777777776679********** PP
   S: 234  irfnllaivadrrviktlrlnvlkid......................keLlkLlkdieseeekieaqlddekekrk 288
           irf+lla+v++r+ ++ + l+  +                        + L   l++++  +e  ++++  e+ek k
   Q: 219  IRFSLLAVVKNRKEMYVAELKEYQRKrerilqqlgalqadkyaekssyEALDRSLSEVNIGIETVSQKIVLEEEKSK 295
           *************9988887655555789******************9889999*********************** PP
   S: 289  kfkiddirRtenydeficifikdlaregilrklv 322
           ++k +++rR++ny+ f++ f+k la ++ l+ l 
   Q: 296  NWKKENMRRKHNYVPFLFNFLKILADKKKLKPLI 329
           *************************999888765 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MSWLPVESDP GIFTEIIQQM QVKGVQVEEL YSLDFNSLDE IRPVYGLILL YKWRPEEKEN 60
RVVITEPNPN FFFASQIINN ACATQAILSV LMNSSSIDIG SELSELKQFA KEFPPELKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTAATTCA GTCCCATTTT CACAGATCAT GTCTTGGCTT CCTGTAGAAT CTGATCCTGG 60
TATATTTTCT CTCCTCCAAT TTCGGGTTTT TTGTTGTTTT CTAGATTAAT AAAGAGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0010016--P:shoot system morphogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_488484

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-006850	Arabidopsis thaliana	96.41	0.00e+00	630.00
IUUC-Bdi-014551	Brachypodium distachyon	63.14	2.00e-114	404.00
IUUC-Tur-126366	Triticum urartu	59.52	4.00e-101	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence