iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000061161.6	ENSDART00000086924.5	ENSDARP00000081358.4
ENSDARG00000061161.6	ENSDART00000137282.1	ENSDARP00000121071.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.60e-28	100.1	16	125

Active Site

Position(s)	Description	Evidence
94	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk..ifhPnvyenGkvClsilk 87
           Rlk+++ +++kdp+++i a+p  + ++ ew++l+ Gpe+tpYegg+++ ++ fp+++PfkPP++ ++t+  +f++    n+++Clsi +
   Q: 16   RLKQDYLRIKKDPVPYICAEPLPS-NILEWHYLVRGPEKTPYEGGYYHGKLIFPREFPFKPPSIYMITPngRFKC----NTRLCLSITD 99
           99**********************.9*******************************************555555....59*******8 PP
   S: 88   .eeekWspalsvesvllsiqsllaep 112
            ++++W+pa+sv+++l+++ s++ e 
   Q: 100  fHPDTWNPAWSVSTILTGLLSFMVEK 125
           89********************9764 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSNNLNKRAP TTATQRLKQD YLRIKKDPVP YICAEPLPSN ILEWHYLVRG PEKTPYEGGY 60
YHGKLIFPRE FPFKPPSIYM ITPNGRFKCN TRLCLSITDF HPDTWNPAWS VSTILTGLLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACTTCCT GGTGTTGCGG TGGCCATATT GGCATGGGGG ATAGATGACA ATTTCACCTT 60
AGCCGAAGAG CTACATTTTT GTTATTTTTG AAAGTTTATC CAGGGCGTGT TCACTCGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

dre:100037384

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002152	Ailuropoda melanoleuca	89.19	5.00e-127	446.00
IUUC-Atr-003156	Amborella trichopoda	52.69	6.00e-53	200.00
IUUC-Apl-004224	Anas platyrhynchos	90.00	4.00e-111	394.00
IUUC-Aca-005049	Anolis carolinensis	90.11	4.00e-127	447.00
IUUC-Aly-006195	Arabidopsis lyrata	53.16	1.00e-49	189.00
IUUC-Ath-006640	Arabidopsis thaliana	53.16	3.00e-50	191.00
IUUC-Ago-007987	Ashbya gossypii	49.46	2.00e-52	199.00
IUUC-Acl-008060	Aspergillus clavatus	55.63	6.00e-43	167.00
IUUC-Afl-008561	Aspergillus flavus	55.63	1.00e-42	166.00
IUUC-Afu-008860	Aspergillus fumigatus	55.63	1.00e-42	166.00
IUUC-Ani-009333	Aspergillus nidulans	54.23	7.00e-42	164.00
IUUC-Ang-009810	Aspergillus niger	56.34	5.00e-43	167.00
IUUC-Aor-010127	Aspergillus oryzae	55.63	1.00e-42	166.00
IUUC-Ate-010362	Aspergillus terreus	55.63	1.00e-42	166.00
IUUC-Ame-010627	Astyanax mexicanus	95.40	2.00e-140	491.00
IUUC-Bgr-012069	Blumeria graminis	51.41	6.00e-40	157.00
IUUC-Bta-012472	Bos taurus	88.80	4.00e-125	440.00
IUUC-Bci-013843	Botrytis cinerea	54.23	9.00e-41	160.00
IUUC-Bdi-014467	Brachypodium distachyon	53.01	1.00e-50	192.00
IUUC-Bol-015471	Brassica oleracea	50.85	5.00e-52	197.00
IUUC-Bra-017799	Brassica rapa	54.09	2.00e-49	188.00
IUUC-Cel-018278	Caenorhabditis elegans	60.23	8.00e-52	196.00
IUUC-Cja-018817	Callithrix jacchus	84.68	2.00e-103	369.00
IUUC-Cfa-020885	Canis familiaris	89.19	4.00e-127	447.00
IUUC-Cpo-022326	Cavia porcellus	89.58	2.00e-131	461.00
IUUC-Cre-022635	Chlamydomonas reinhardtii	58.06	5.00e-54	203.00
IUUC-Csa-023646	Chlorocebus sabaeus	88.03	6.00e-129	452.00
IUUC-Cho-025075	Choloepus hoffmanni	77.27	7.00e-64	235.00
IUUC-Cin-025389	Ciona intestinalis	74.29	2.00e-80	290.00
IUUC-Csv-026315	Ciona savignyi	57.77	2.00e-83	301.00
IUUC-Cgl-026602	Colletotrichum gloeosporioides	53.52	7.00e-42	164.00
IUUC-Cne-026808	Cryptococcus neoformans	50.70	5.00e-42	163.00
IUUC-Dno-029667	Dasypus novemcinctus	86.49	3.00e-126	444.00
IUUC-Dor-030747	Dipodomys ordii	73.82	3.00e-105	374.00
IUUC-Dse-031231	Dothistroma septosporum	50.00	3.00e-39	155.00
IUUC-Dme-031841	Drosophila melanogaster	51.46	2.00e-78	285.00
IUUC-Ete-032258	Echinops telfairi	79.57	3.00e-115	407.00
IUUC-Eca-033602	Equus caballus	66.80	2.00e-89	321.00
IUUC-Eeu-034443	Erinaceus europaeus	87.06	8.00e-96	342.00
IUUC-Fca-036167	Felis catus	83.91	3.00e-113	400.00
IUUC-Fal-037114	Ficedula albicollis	86.00	2.00e-96	345.00
IUUC-Fox-037957	Fusarium oxysporum	58.87	4.00e-40	158.00
IUUC-Fso-038277	Fusarium solani	54.93	5.00e-43	167.00
IUUC-Gmo-039501	Gadus morhua	85.44	5.00e-112	397.00
IUUC-Ggr-040010	Gaeumannomyces graminis	57.04	2.00e-43	169.00
IUUC-Gga-041257	Gallus gallus	90.00	8.00e-110	389.00
IUUC-Gac-041433	Gasterosteus aculeatus	85.44	3.00e-111	394.00
IUUC-Gma-043529	Glycine max	46.00	3.00e-53	201.00
IUUC-Ggo-044437	Gorilla gorilla	83.04	1.00e-104	372.00
IUUC-Hsa-046693	Homo sapiens	88.03	2.00e-128	451.00
IUUC-Itr-048477	Ictidomys tridecemlineatus	88.42	3.00e-125	441.00
IUUC-Kpa-049391	Komagataella pastoris	54.09	2.00e-41	162.00
IUUC-Lch-049617	Latimeria chalumnae	88.80	6.00e-117	413.00
IUUC-Lpe-050949	Leersia perrieri	51.20	6.00e-49	187.00
IUUC-Loc-052157	Lepisosteus oculatus	87.79	1.00e-118	418.00
IUUC-Lma-053128	Leptosphaeria maculans	55.07	1.00e-41	163.00
IUUC-Laf-054455	Loxodonta africana	87.64	2.00e-117	415.00
IUUC-Mcc-054756	Macaca mulatta	88.03	6.00e-129	452.00
IUUC-Meu-056106	Macropus eugenii	73.88	2.00e-92	331.00
IUUC-Mor-057202	Magnaporthe oryzae	54.93	2.00e-42	166.00
IUUC-Mpo-057349	Magnaporthe poae	56.34	6.00e-43	167.00
IUUC-Mtr-058271	Medicago truncatula	50.29	3.00e-48	185.00
IUUC-Mla-058894	Melampsora laricipopulina	52.45	3.00e-43	167.00
IUUC-Mga-059493	Meleagris gallopavo	90.00	8.00e-110	389.00
IUUC-Mvi-060232	Microbotryum violaceum	48.67	5.00e-42	164.00
IUUC-Mmr-060957	Microcebus murinus	89.19	8.00e-131	459.00
IUUC-Mdo-062141	Monodelphis domestica	88.80	9.00e-121	426.00
IUUC-Mmu-063882	Mus musculus	87.26	3.00e-122	431.00
IUUC-Mac-064530	Musa acuminata	47.47	5.00e-51	194.00
IUUC-Mpu-065902	Mustela putorius furo	89.19	4.00e-127	447.00
IUUC-Mlu-068008	Myotis lucifugus	88.03	3.00e-124	437.00
IUUC-Nfi-068515	Neosartorya fischeri	55.63	8.00e-43	167.00
IUUC-Ncr-068755	Neurospora crassa	53.52	4.00e-41	161.00
IUUC-Opr-071201	Ochotona princeps	86.07	4.00e-86	310.00
IUUC-Ont-071311	Oreochromis niloticus	85.44	3.00e-108	384.00
IUUC-Oan-073310	Ornithorhynchus anatinus	86.92	2.00e-121	427.00
IUUC-Ocu-074514	Oryctolagus cuniculus	88.42	1.00e-128	451.00
IUUC-Oba-075200	Oryza barthii	51.83	3.00e-49	187.00
IUUC-Obr-076396	Oryza brachyantha	49.17	8.00e-50	190.00
IUUC-Ogl-077398	Oryza glaberrima	51.83	5.00e-49	187.00
IUUC-Ogu-078362	Oryza glumaepatula	51.83	3.00e-49	187.00
IUUC-Oin-079625	Oryza indica	51.83	3.00e-49	187.00
IUUC-Olo-080620	Oryza longistaminata	45.19	3.00e-29	121.00
IUUC-Ome-081187	Oryza meridionalis	51.83	5.00e-49	187.00
IUUC-Oni-082271	Oryza nivara	51.83	6.00e-49	187.00
IUUC-Opu-083487	Oryza punctata	51.22	3.00e-48	184.00
IUUC-Oru-085263	Oryza rufipogon	51.83	3.00e-49	187.00
IUUC-Osa-085694	Oryza sativa	51.83	3.00e-49	187.00
IUUC-Ola-086450	Oryzias latipes	86.10	4.00e-118	417.00
IUUC-Olu-087733	Ostreococcus lucimarinus	41.27	1.00e-25	109.00
IUUC-Oga-088054	Otolemur garnettii	83.27	3.00e-120	424.00
IUUC-Oar-089486	Ovis aries	88.80	2.00e-125	441.00
IUUC-Pan-092633	Papio anubis	88.03	6.00e-129	452.00
IUUC-Psi-093165	Pelodiscus sinensis	84.89	1.00e-36	145.00
IUUC-Pno-095025	Phaeosphaeria nodorum	55.80	8.00e-43	167.00
IUUC-Ppa-095641	Physcomitrella patens	56.33	4.00e-54	204.00
IUUC-Pfo-096423	Poecilia formosa	86.97	1.00e-104	372.00
IUUC-Pab-097771	Pongo abelii	88.42	3.00e-129	454.00
IUUC-Pop-099714	Populus trichocarpa	53.71	1.00e-54	206.00
IUUC-Pca-100493	Procavia capensis	76.74	1.00e-75	275.00
IUUC-Ppe-102054	Prunus persica	48.19	8.00e-52	196.00
IUUC-Pva-102224	Pteropus vampyrus	87.26	3.00e-122	431.00
IUUC-Pgr-103530	Puccinia graminis	50.00	2.00e-46	178.00
IUUC-Ptt-103776	Puccinia triticina	50.00	1.00e-45	176.00
IUUC-Pte-104166	Pyrenophora teres	53.62	2.00e-41	162.00
IUUC-Pyt-104570	Pyrenophora triticirepentis	53.62	3.00e-41	162.00
IUUC-Rno-105593	Rattus norvegicus	87.26	1.00e-122	432.00
IUUC-Sce-106212	Saccharomyces cerevisiae	43.43	3.00e-52	197.00
IUUC-Sha-106767	Sarcophilus harrisii	89.19	3.00e-121	427.00
IUUC-Sja-107907	Schizosaccharomyces japonicus	50.31	8.00e-48	183.00
IUUC-Spo-108094	Schizosaccharomyces pombe	53.09	2.00e-48	185.00
IUUC-Ssl-108556	Sclerotinia sclerotiorum	54.23	5.00e-41	161.00
IUUC-Smo-108965	Selaginella moellendorffii	47.80	3.00e-55	207.00
IUUC-Sit-110407	Setaria italica	55.21	2.00e-51	195.00
IUUC-Sly-111642	Solanum lycopersicum	49.15	4.00e-48	184.00
IUUC-Stu-112336	Solanum tuberosum	48.59	3.00e-47	181.00
IUUC-Sbi-114327	Sorghum bicolor	55.21	5.00e-51	194.00
IUUC-Sre-115170	Sporisorium reilianum	51.48	6.00e-42	164.00
IUUC-Ssc-116385	Sus scrofa	88.80	1.00e-125	442.00
IUUC-Tgu-117041	Taeniopygia guttata	86.10	1.00e-101	362.00
IUUC-Tru-117697	Takifugu rubripes	86.97	2.00e-115	408.00
IUUC-Tsy-119024	Tarsius syrichta	80.31	1.00e-116	412.00
IUUC-Tni-120466	Tetraodon nigroviridis	84.53	1.00e-111	395.00
IUUC-Tca-121569	Theobroma cacao	51.46	2.00e-50	192.00
IUUC-Tre-121882	Trichoderma reesei	56.34	6.00e-43	167.00
IUUC-Tvi-122466	Trichoderma virens	55.63	1.00e-42	166.00
IUUC-Tae-124797	Triticum aestivum	53.05	2.00e-50	192.00
IUUC-Tur-126536	Triticum urartu	53.42	3.00e-50	191.00
IUUC-Tme-127051	Tuber melanosporum	57.75	3.00e-45	175.00
IUUC-Tbe-128095	Tupaia belangeri	87.44	2.00e-90	325.00
IUUC-Ttr-128466	Tursiops truncatus	89.58	2.00e-126	444.00
IUUC-Uma-129383	Ustilago maydis	52.87	2.00e-41	162.00
IUUC-Vda-130013	Verticillium dahliae	55.22	1.00e-40	160.00
IUUC-Vvi-131251	Vitis vinifera	51.90	7.00e-47	181.00
IUUC-Xtr-132408	Xenopus tropicalis	89.23	1.00e-136	478.00
IUUC-Xma-133893	Xiphophorus maculatus	87.36	6.00e-105	373.00
IUUC-Yli-134618	Yarrowia lipolytica	59.21	2.00e-51	195.00
IUUC-Zma-135216	Zea mays	53.37	6.00e-50	190.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence