iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013404

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02061261

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000034225.3	ENSBTAT00000048510.3	ENSBTAP00000052514.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-40	134.7	504	540
UBD/Beta-Prp	7.40e-68	229.0	266	561

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHtd +t+l f +d  l++s+s D++++vWD+r+ ++
   Q: 504  GHTDNITSLTFsPDsSLVASASMDNSVRVWDIRSSHC 540
           8***********9999***************998876 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilv 68
            ++   +spd++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l+
   Q: 266  LLNTAEVSPDSKLLAAGFDNSCIKLWSLRSKKLksephqvdvsrihlacdfleeeddeddnlgteMKVLRGHCGPVYSTRFLADSSGLL 354
           5666789*********************************************************9999********************* PP
   S: 69   tgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGsl 157
           ++seD+ i+ wdl +++ ++ ++gh + v++l++sp + +++s+shdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+
   Q: 355  SCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPHSLYFASASHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGST 442
           **************************************************************.************************** PP
   S: 158  DrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
           D+tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+
   Q: 443  DKTVRLWSTQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLVASASMDNSV 530
           *******************9.******************************************************************** PP
   S: 247  riWdlrsgdllktlqlhnssvisvavlsfgd 277
           r+Wd+rs+ + +   ++ s ++ v + ++++
   Q: 531  RVWDIRSSHCSTPADGSSSELVGVYTGQMSN 561
           ***********99999997777777644443 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYGDADGPKQ ILRLSQSTEE MAASLTVQSE SGCANIVSAA 60
PCQAEPQQYE VQFGRLRNFL TDSDSQHSHE VMPLLYPLFV YLHLTLIQNS PKSTVESFYS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGGG TCCGCACGGA GCAGATCCAG ATGGCCGTGT CCTGCTACCT CAAACGCCGG 60
CAGTACGGGG ATGCGGACGG TCCGGTGAAA GCAAATACTG CGGCTATCGC AGAGCACTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	93.89	0.00e+00	1058.00
IUUC-Apl-003636	Anas platyrhynchos	87.99	0.00e+00	1059.00
IUUC-Aca-004229	Anolis carolinensis	88.12	0.00e+00	1032.00
IUUC-Ame-010599	Astyanax mexicanus	66.67	0.00e+00	798.00
IUUC-Cja-019643	Callithrix jacchus	93.38	0.00e+00	1060.00
IUUC-Cfa-020913	Canis familiaris	93.72	0.00e+00	1059.00
IUUC-Cpo-021777	Cavia porcellus	90.83	0.00e+00	1032.00
IUUC-Csa-024184	Chlorocebus sabaeus	93.04	0.00e+00	1059.00
IUUC-Cho-024638	Choloepus hoffmanni	92.36	0.00e+00	1042.00
IUUC-Cin-025618	Ciona intestinalis	35.18	3.00e-86	312.00
IUUC-Csv-025874	Ciona savignyi	42.58	7.00e-76	278.00
IUUC-Dre-028817	Danio rerio	66.39	0.00e+00	785.00
IUUC-Dno-029969	Dasypus novemcinctus	86.59	0.00e+00	998.00
IUUC-Dor-031117	Dipodomys ordii	90.66	0.00e+00	1057.00
IUUC-Ete-032712	Echinops telfairi	85.40	0.00e+00	944.00
IUUC-Eca-033742	Equus caballus	93.38	0.00e+00	1056.00
IUUC-Eeu-035096	Erinaceus europaeus	90.51	0.00e+00	1063.00
IUUC-Fca-035769	Felis catus	93.06	0.00e+00	1077.00
IUUC-Fal-036645	Ficedula albicollis	87.59	0.00e+00	997.00
IUUC-Fso-038302	Fusarium solani	33.77	3.00e-38	153.00
IUUC-Gmo-038636	Gadus morhua	63.77	0.00e+00	757.00
IUUC-Gga-040144	Gallus gallus	88.29	0.00e+00	1035.00
IUUC-Gac-041716	Gasterosteus aculeatus	67.67	0.00e+00	792.00
IUUC-Ggo-044568	Gorilla gorilla	93.21	0.00e+00	1058.00
IUUC-Hsa-046178	Homo sapiens	93.21	0.00e+00	1058.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	88.29	0.00e+00	1044.00
IUUC-Lch-050501	Latimeria chalumnae	74.82	0.00e+00	827.00
IUUC-Loc-052895	Lepisosteus oculatus	81.74	0.00e+00	628.00
IUUC-Laf-053950	Loxodonta africana	89.30	0.00e+00	1028.00
IUUC-Mcc-055450	Macaca mulatta	93.04	0.00e+00	1054.00
IUUC-Meu-056182	Macropus eugenii	84.72	0.00e+00	970.00
IUUC-Mga-059619	Meleagris gallopavo	88.46	0.00e+00	1038.00
IUUC-Mmr-061074	Microcebus murinus	92.05	0.00e+00	1067.00
IUUC-Mdo-062307	Monodelphis domestica	90.19	0.00e+00	856.00
IUUC-Mmu-063226	Mus musculus	89.47	0.00e+00	1006.00
IUUC-Mpu-066016	Mustela putorius furo	93.04	0.00e+00	1052.00
IUUC-Mlu-067257	Myotis lucifugus	86.31	0.00e+00	1037.00
IUUC-Nle-070139	Nomascus leucogenys	93.04	0.00e+00	1056.00
IUUC-Opr-070243	Ochotona princeps	89.13	0.00e+00	1039.00
IUUC-Ont-072686	Oreochromis niloticus	69.12	0.00e+00	817.00
IUUC-Oan-073670	Ornithorhynchus anatinus	80.89	0.00e+00	815.00
IUUC-Ocu-074525	Oryctolagus cuniculus	92.70	0.00e+00	1077.00
IUUC-Ola-086524	Oryzias latipes	68.50	0.00e+00	840.00
IUUC-Oga-088540	Otolemur garnettii	92.53	0.00e+00	1046.00
IUUC-Oar-089793	Ovis aries	92.70	0.00e+00	1000.00
IUUC-Ptr-091154	Pan troglodytes	93.21	0.00e+00	1058.00
IUUC-Pan-092759	Papio anubis	93.04	0.00e+00	1054.00
IUUC-Psi-094008	Pelodiscus sinensis	86.59	0.00e+00	1033.00
IUUC-Pma-094593	Petromyzon marinus	45.53	3.00e-126	445.00
IUUC-Pfo-097409	Poecilia formosa	67.00	0.00e+00	795.00
IUUC-Pab-097946	Pongo abelii	81.32	0.00e+00	900.00
IUUC-Pca-100727	Procavia capensis	85.40	0.00e+00	947.00
IUUC-Pva-103211	Pteropus vampyrus	83.53	0.00e+00	978.00
IUUC-Ptt-103995	Puccinia triticina	44.41	3.00e-71	263.00
IUUC-Rno-105236	Rattus norvegicus	89.64	0.00e+00	1006.00
IUUC-Sha-106833	Sarcophilus harrisii	89.53	0.00e+00	1045.00
IUUC-Sar-113381	Sorex araneus	93.38	0.00e+00	1088.00
IUUC-Ssc-116421	Sus scrofa	93.72	0.00e+00	1111.00
IUUC-Tgu-117143	Taeniopygia guttata	88.46	0.00e+00	1065.00
IUUC-Tru-118680	Takifugu rubripes	68.28	0.00e+00	820.00
IUUC-Tsy-119622	Tarsius syrichta	77.42	0.00e+00	801.00
IUUC-Tni-120131	Tetraodon nigroviridis	68.28	0.00e+00	824.00
IUUC-Tbe-127656	Tupaia belangeri	84.09	3.00e-75	275.00
IUUC-Ttr-129171	Tursiops truncatus	95.25	0.00e+00	1065.00
IUUC-Xtr-132241	Xenopus tropicalis	78.81	0.00e+00	919.00
IUUC-Xma-133554	Xiphophorus maculatus	67.42	0.00e+00	733.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence