iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035769

Ensembl Protein ID

ENSFCAP00000007095.3

UniProt Accession

M3W847; M3W847_FELCA

Genbank Protein ID

ENSFCAP00000007095

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02018425

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000007661.3	ENSFCAT00000007663.3	ENSFCAP00000007095.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-41	137.1	510	542
UBD/Beta-Prp	5.40e-68	229.4	273	572

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++s+s D++++vWD+r
   Q: 510  GHTDNITSLTFsPDsSLIASASMDNSVRVWDIR 542
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g+++++ik+w++++ kl                                ++ l gh ++v++++f  d++ l++
   Q: 273  LNTAEISPDSKLLAAGFDNSCIKLWSLRSRKLksephqvdvsrihlacdileeeddeddnagteMKILRGHCGPVYSTRFLADSSGLLS 361
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 362  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 449
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 450  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASASMDNSVR 537
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhn...........ssvisva 271
           +Wd+r+  +     ++            s+v sv+
   Q: 538  VWDIRNTYCSAPADGSSgelvgvytgqmSNVLSVQ 572
           **877777766655555222222222225555555 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MKRVRTEQIQ MAASCYLKRR QYVDSDGPLK QGLRLSQTAE EMAAHLTALV QSESGCANIV 60
SAAPCQAEPQ QYEVQFGRLR NFLTDSDSQH SHEVMPLLYP LFVYLHLNLV QNSPKSTVES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGTCTGG CTCCTCATTT TACCCATGTG ACGTCCTCGT TGGGTTGGAC GACCTCGCAA 60
ATGCCTCAGT GTTCTGTGGT TCCCTCTGAA GGTCATGAAA CGAGTGCGCA CCGAGCAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	97.97	0.00e+00	1108.00
IUUC-Apl-003636	Anas platyrhynchos	92.07	0.00e+00	1123.00
IUUC-Aca-004229	Anolis carolinensis	91.03	0.00e+00	1091.00
IUUC-Ame-010599	Astyanax mexicanus	67.00	0.00e+00	818.00
IUUC-Bta-013404	Bos taurus	93.06	0.00e+00	1049.00
IUUC-Cja-019643	Callithrix jacchus	97.80	0.00e+00	1126.00
IUUC-Cfa-020913	Canis familiaris	98.48	0.00e+00	1134.00
IUUC-Cpo-021777	Cavia porcellus	93.74	0.00e+00	1066.00
IUUC-Csa-024184	Chlorocebus sabaeus	97.80	0.00e+00	1129.00
IUUC-Cho-024638	Choloepus hoffmanni	96.95	0.00e+00	1094.00
IUUC-Cin-025618	Ciona intestinalis	35.33	2.00e-91	329.00
IUUC-Csv-025874	Ciona savignyi	33.86	2.00e-90	326.00
IUUC-Dre-028817	Danio rerio	66.89	0.00e+00	804.00
IUUC-Dno-029969	Dasypus novemcinctus	88.83	0.00e+00	1055.00
IUUC-Dor-031117	Dipodomys ordii	94.42	0.00e+00	1102.00
IUUC-Ete-032712	Echinops telfairi	88.83	0.00e+00	984.00
IUUC-Eca-033742	Equus caballus	98.48	0.00e+00	1132.00
IUUC-Eeu-035096	Erinaceus europaeus	94.76	0.00e+00	1125.00
IUUC-Fal-036645	Ficedula albicollis	91.76	0.00e+00	1061.00
IUUC-Fso-038302	Fusarium solani	33.98	6.00e-40	159.00
IUUC-Gmo-038636	Gadus morhua	63.95	0.00e+00	771.00
IUUC-Gga-040144	Gallus gallus	91.54	0.00e+00	1092.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.33	0.00e+00	810.00
IUUC-Ggo-044568	Gorilla gorilla	97.97	0.00e+00	1128.00
IUUC-Hsa-046178	Homo sapiens	97.97	0.00e+00	1128.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	89.00	0.00e+00	1079.00
IUUC-Lch-050501	Latimeria chalumnae	78.37	0.00e+00	885.00
IUUC-Loc-052895	Lepisosteus oculatus	83.33	0.00e+00	652.00
IUUC-Laf-053950	Loxodonta africana	92.55	0.00e+00	1068.00
IUUC-Mcc-055450	Macaca mulatta	97.80	0.00e+00	1124.00
IUUC-Meu-056182	Macropus eugenii	88.49	0.00e+00	1018.00
IUUC-Mga-059619	Meleagris gallopavo	91.71	0.00e+00	1095.00
IUUC-Mmr-061074	Microcebus murinus	95.95	0.00e+00	1134.00
IUUC-Mdo-062307	Monodelphis domestica	93.36	0.00e+00	897.00
IUUC-Mmu-063226	Mus musculus	92.05	0.00e+00	1058.00
IUUC-Mpu-066016	Mustela putorius furo	97.63	0.00e+00	1103.00
IUUC-Mlu-067257	Myotis lucifugus	88.19	0.00e+00	1077.00
IUUC-Nle-070139	Nomascus leucogenys	97.80	0.00e+00	1127.00
IUUC-Opr-070243	Ochotona princeps	91.88	0.00e+00	1077.00
IUUC-Ont-072686	Oreochromis niloticus	68.94	0.00e+00	833.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.10	0.00e+00	847.00
IUUC-Ocu-074525	Oryctolagus cuniculus	96.79	0.00e+00	1127.00
IUUC-Ola-086524	Oryzias latipes	68.11	0.00e+00	851.00
IUUC-Oga-088540	Otolemur garnettii	96.45	0.00e+00	1110.00
IUUC-Oar-089793	Ovis aries	90.02	0.00e+00	982.00
IUUC-Ptr-091154	Pan troglodytes	97.97	0.00e+00	1128.00
IUUC-Pan-092759	Papio anubis	97.80	0.00e+00	1124.00
IUUC-Psi-094008	Pelodiscus sinensis	89.17	0.00e+00	1086.00
IUUC-Pma-094593	Petromyzon marinus	45.82	4.00e-132	464.00
IUUC-Pfo-097409	Poecilia formosa	67.66	0.00e+00	807.00
IUUC-Pab-097946	Pongo abelii	85.79	0.00e+00	973.00
IUUC-Pca-100727	Procavia capensis	89.34	0.00e+00	994.00
IUUC-Pva-103211	Pteropus vampyrus	84.94	0.00e+00	1011.00
IUUC-Ptt-103995	Puccinia triticina	42.48	1.00e-70	262.00
IUUC-Rno-105236	Rattus norvegicus	92.55	0.00e+00	1042.00
IUUC-Sha-106833	Sarcophilus harrisii	93.27	0.00e+00	1090.00
IUUC-Sar-113381	Sorex araneus	98.31	0.00e+00	1159.00
IUUC-Ssc-116421	Sus scrofa	94.75	0.00e+00	1130.00
IUUC-Tgu-117143	Taeniopygia guttata	92.55	0.00e+00	1128.00
IUUC-Tru-118680	Takifugu rubripes	67.44	0.00e+00	830.00
IUUC-Tsy-119622	Tarsius syrichta	81.39	0.00e+00	852.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.44	0.00e+00	832.00
IUUC-Tbe-127656	Tupaia belangeri	94.32	1.00e-88	320.00
IUUC-Ttr-129171	Tursiops truncatus	94.59	0.00e+00	1069.00
IUUC-Xtr-132241	Xenopus tropicalis	80.07	0.00e+00	952.00
IUUC-Xma-133554	Xiphophorus maculatus	68.16	0.00e+00	744.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence