iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041596

Ensembl Protein ID

ENSGACP00000020100.1

UniProt Accession

G3PR65; G3PR65_GASAC

Protein Name

Uncharacterized protein

Gene Name

FZR1 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000015236.1	ENSGACT00000020139.1	ENSGACP00000020100.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.40e-148	494.5	178	481
E3 adaptor/Cullin RING/DCX/DWD	5.60e-27	93.1	314	344

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 178  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGYVQIWDAAAGKK 266
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd+ il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss  P+++++
   Q: 267  LSVLEGHTARVGALAWNADQLSSGSRDRVILQRDIRAPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSVLPVQQYT 355
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 356  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCTDTGSQVCNLAWSKHTNELVSTHGYSQNQILVWKYPSLTQVAKLTG 444
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k ++
   Q: 445  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKMRS 481
           ********************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 314  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 344
           8**********98889**************9 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MDQDYECRLL RQINIQNENA SPIKAVGAVR ALTPTTSPLS SPSKHGDRFI PSRAGANWSV 60
NFHRINEIEK SHNQNRKTKD GTTDSNKADG LAYSALLKNE LLGAGIEKVQ DPQSEDRRLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCCGTGA TGCTTTGCGG ACCCAAATTG ATCAGCAAAA GAAAACAATT GTATCTTGCA 60
TGCTCTGTTT TAAAGAGTAA AACAAAATAA AACAAGATAT TTCCACTAGA ATTAATACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	54.43	4.00e-115	408.00
IUUC-Atr-002753	Amborella trichopoda	57.49	4.00e-134	471.00
IUUC-Apl-003212	Anas platyrhynchos	90.93	0.00e+00	924.00
IUUC-Aly-005442	Arabidopsis lyrata	56.76	8.00e-139	486.00
IUUC-Ath-006938	Arabidopsis thaliana	57.18	5.00e-137	481.00
IUUC-Ago-007784	Ashbya gossypii	42.48	2.00e-96	346.00
IUUC-Ame-011011	Astyanax mexicanus	90.96	0.00e+00	876.00
IUUC-Bgr-012013	Blumeria graminis	50.69	2.00e-131	462.00
IUUC-Bta-012586	Bos taurus	90.52	0.00e+00	916.00
IUUC-Bdi-014981	Brachypodium distachyon	71.15	9.00e-130	457.00
IUUC-Bol-016301	Brassica oleracea	55.19	5.00e-138	484.00
IUUC-Bra-017453	Brassica rapa	55.19	3.00e-138	484.00
IUUC-Cel-018472	Caenorhabditis elegans	64.58	5.00e-144	504.00
IUUC-Cpo-021537	Cavia porcellus	91.13	0.00e+00	920.00
IUUC-Csa-023389	Chlorocebus sabaeus	90.32	0.00e+00	917.00
IUUC-Cin-025327	Ciona intestinalis	68.32	0.00e+00	627.00
IUUC-Csv-025921	Ciona savignyi	65.02	0.00e+00	659.00
IUUC-Cne-026933	Cryptococcus neoformans	59.42	2.00e-127	449.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	1.00e-117	417.00
IUUC-Dre-027470	Danio rerio	90.54	0.00e+00	874.00
IUUC-Dno-029629	Dasypus novemcinctus	82.46	0.00e+00	745.00
IUUC-Dme-031858	Drosophila melanogaster	69.84	0.00e+00	677.00
IUUC-Fal-036895	Ficedula albicollis	90.93	0.00e+00	924.00
IUUC-Fso-038420	Fusarium solani	49.90	6.00e-132	464.00
IUUC-Gmo-039544	Gadus morhua	97.38	0.00e+00	938.00
IUUC-Gga-041025	Gallus gallus	90.73	0.00e+00	921.00
IUUC-Ggo-045599	Gorilla gorilla	89.98	0.00e+00	879.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	2.00e-106	378.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	90.93	0.00e+00	919.00
IUUC-Kpa-049239	Komagataella pastoris	46.52	5.00e-123	434.00
IUUC-Lch-049827	Latimeria chalumnae	91.13	0.00e+00	890.00
IUUC-Lpe-051568	Leersia perrieri	47.72	2.00e-112	399.00
IUUC-Loc-052856	Lepisosteus oculatus	92.94	0.00e+00	921.00
IUUC-Mcc-055601	Macaca mulatta	90.32	0.00e+00	917.00
IUUC-Meu-056276	Macropus eugenii	67.33	7.00e-172	596.00
IUUC-Mla-059048	Melampsora laricipopulina	50.30	2.00e-119	423.00
IUUC-Mga-060097	Meleagris gallopavo	85.00	0.00e+00	850.00
IUUC-Mvi-060465	Microbotryum violaceum	50.69	2.00e-130	459.00
IUUC-Mmr-061151	Microcebus murinus	81.51	0.00e+00	789.00
IUUC-Mdo-063062	Monodelphis domestica	90.52	0.00e+00	922.00
IUUC-Mmu-063731	Mus musculus	90.32	0.00e+00	913.00
IUUC-Mac-065208	Musa acuminata	56.95	9.00e-129	453.00
IUUC-Mpu-066173	Mustela putorius furo	90.52	0.00e+00	916.00
IUUC-Nle-070163	Nomascus leucogenys	90.32	0.00e+00	917.00
IUUC-Opr-070974	Ochotona princeps	92.12	3.00e-154	536.00
IUUC-Ont-072272	Oreochromis niloticus	98.60	0.00e+00	957.00
IUUC-Oan-073634	Ornithorhynchus anatinus	96.60	3.00e-171	593.00
IUUC-Oba-075417	Oryza barthii	63.17	2.00e-111	396.00
IUUC-Obr-076123	Oryza brachyantha	57.95	3.00e-128	452.00
IUUC-Ogl-077294	Oryza glaberrima	52.70	6.00e-127	447.00
IUUC-Ogu-077996	Oryza glumaepatula	52.48	1.00e-125	442.00
IUUC-Oin-080172	Oryza indica	70.49	2.00e-126	446.00
IUUC-Olo-081068	Oryza longistaminata	70.49	3.00e-126	444.00
IUUC-Ome-081250	Oryza meridionalis	53.03	2.00e-127	449.00
IUUC-Oni-083048	Oryza nivara	52.70	6.00e-127	447.00
IUUC-Opu-083333	Oryza punctata	52.81	1.00e-126	446.00
IUUC-Oru-085001	Oryza rufipogon	52.70	6.00e-127	447.00
IUUC-Osa-086243	Oryza sativa	52.70	6.00e-127	447.00
IUUC-Ola-087094	Oryzias latipes	97.41	0.00e+00	910.00
IUUC-Oga-088911	Otolemur garnettii	90.52	0.00e+00	916.00
IUUC-Oar-089508	Ovis aries	90.52	0.00e+00	916.00
IUUC-Psi-093702	Pelodiscus sinensis	90.76	0.00e+00	922.00
IUUC-Pno-095139	Phaeosphaeria nodorum	60.37	4.00e-113	402.00
IUUC-Pfo-096309	Poecilia formosa	98.99	0.00e+00	959.00
IUUC-Pab-098762	Pongo abelii	73.95	0.00e+00	699.00
IUUC-Pop-098924	Populus trichocarpa	55.73	2.00e-133	469.00
IUUC-Ppe-101924	Prunus persica	56.28	6.00e-136	477.00
IUUC-Pgr-103466	Puccinia graminis	51.50	1.00e-117	417.00
IUUC-Ptt-103888	Puccinia triticina	53.96	2.00e-107	383.00
IUUC-Pte-104097	Pyrenophora teres	48.78	1.00e-133	469.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	45.40	6.00e-115	407.00
IUUC-Rno-105028	Rattus norvegicus	90.32	0.00e+00	911.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	49.32	9.00e-117	413.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.62	1.00e-115	409.00
IUUC-Sit-110563	Setaria italica	53.25	6.00e-122	431.00
IUUC-Stu-112491	Solanum tuberosum	55.12	2.00e-132	465.00
IUUC-Sar-112962	Sorex araneus	78.63	9.00e-117	412.00
IUUC-Sbi-114489	Sorghum bicolor	54.75	4.00e-124	437.00
IUUC-Sre-115222	Sporisorium reilianum	48.49	1.00e-131	463.00
IUUC-Ssc-116171	Sus scrofa	90.52	0.00e+00	916.00
IUUC-Tgu-116878	Taeniopygia guttata	80.24	0.00e+00	787.00
IUUC-Tru-118222	Takifugu rubripes	97.60	0.00e+00	947.00
IUUC-Tni-119863	Tetraodon nigroviridis	98.59	0.00e+00	951.00
IUUC-Tca-121599	Theobroma cacao	57.34	5.00e-135	474.00
IUUC-Tae-123489	Triticum aestivum	54.89	5.00e-129	454.00
IUUC-Tur-126545	Triticum urartu	59.94	1.00e-103	369.00
IUUC-Tme-127151	Tuber melanosporum	53.71	2.00e-146	512.00
IUUC-Uma-129555	Ustilago maydis	48.49	7.00e-131	461.00
IUUC-Vda-130027	Verticillium dahliae	50.90	6.00e-134	471.00
IUUC-Vvi-131749	Vitis vinifera	55.13	3.00e-134	471.00
IUUC-Xtr-132808	Xenopus tropicalis	86.72	0.00e+00	877.00
IUUC-Xma-133183	Xiphophorus maculatus	98.99	0.00e+00	959.00
IUUC-Yli-134584	Yarrowia lipolytica	61.83	1.00e-130	460.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence