iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-063074

UUCD1 version

UUC-MoD-00987

Ensembl Protein ID

ENSMODP00000035555.2

UniProt Accession

F7CQH6; F7CQH6_MONDO

Protein Name

Uncharacterized protein

Gene Name

MCCC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000021288.3	ENSMODT00000037142.2	ENSMODP00000035555.2
ENSMODG00000021288.3	ENSMODT00000027090.3	ENSMODP00000026614.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	2.20e-90	302.0	741	927
UBD/Alpha-Helix/UBA	1.90e-06	28.0	687	725

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++kkle+l++rYkdpq++ +igi+g+++fc+dl++dp++i+vL++awk++aat+cefs++ef+dg+t+lgcdsiekl+++++++e+elk
   Q: 741  DRKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELK 829
           78**************999********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           +  +fkd+Y+f+fnfak++gqk+ldl++aia+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+fs++ia+d+snYdeegaWP
   Q: 830  EPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 917
           ***************************************9.************************************************ PP
   S: 179  vliDefveyl 188
           vliD+fve++
   Q: 918  VLIDDFVEFA 927
           ********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q++  +  ++++a+ +L ++++ l++A+++++
   Q: 687  SQKDKVRQFMIfTQSSEKTAVSCLSQNDWKLDVATDNFF 725
           699********9999999*******************99 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGTPLGAAAL LVAERSPWWH VRGLLLPGRW IWKQRTLRHS STGRNNITKV LIANRGEIAC 60
RVIQTARKMG VQSVAVYSEA DRNSAHVDMA DEAYFIGPAA SQQSYLSMEK IIQVAKTSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCCAATTC AGAGACACCT CCCCTCTCAG GATCGAGCTC AGATTGACTA AGTCTCTGGG 60
TCTGTTGGGG ACAGCGGCCC TGACCCAGAG ACCCTGCAAA AGAGGCTCTA GAGTGGGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0092--Biotin
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011761--ATP-grasp
IPR013815--ATP_grasp_subdomain_1
IPR013816--ATP_grasp_subdomain_2
IPR005481--BC-like_N
IPR001882--Biotin_BS
IPR011764--Biotin_carboxylation_dom
IPR005482--Biotin_COase_C
IPR000089--Biotin_lipoyl
IPR005479--CbamoylP_synth_lsu-like_ATP-bd
IPR005176--PONY_dom
IPR016185--PreATP-grasp_dom
IPR011054--Rudment_hybrid_motif
IPR011053--Single_hybrid_motif
IPR009060--UBA-like

PROSITE

PS50975--ATP_GRASP
PS50979--BC
PS00188--BIOTIN
PS00867--CPSASE_2
PS51229--DCUN1

Pfam

PF02785--Biotin_carb_C
PF00289--Biotin_carb_N
PF00364--Biotin_lipoyl
PF02786--CPSase_L_D2
PF03556--Cullin_binding

SMART

SM00878--Biotin_carb_C

Gene Ontology

GO:1905202--C:methylcrotonoyl-CoA carboxylase complex
GO:0005743--C:mitochondrial inner membrane
GO:0005759--C:mitochondrial matrix
GO:0005524--F:ATP binding
GO:0004075--F:biotin carboxylase activity
GO:0046872--F:metal ion binding
GO:0004485--F:methylcrotonoyl-CoA carboxylase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	43.09	2.00e-60	224.00
IUUC-Aml-001879	Ailuropoda melanoleuca	99.22	8.00e-156	542.00
IUUC-Atr-002662	Amborella trichopoda	38.69	3.00e-25	108.00
IUUC-Apl-003451	Anas platyrhynchos	97.32	4.00e-153	533.00
IUUC-Aca-005269	Anolis carolinensis	95.74	3.00e-151	527.00
IUUC-Aly-006285	Arabidopsis lyrata	37.40	1.00e-43	169.00
IUUC-Ath-007531	Arabidopsis thaliana	43.90	9.00e-58	216.00
IUUC-Ago-007806	Ashbya gossypii	23.92	2.00e-19	89.40
IUUC-Acl-008172	Aspergillus clavatus	27.38	4.00e-23	101.00
IUUC-Afl-008569	Aspergillus flavus	29.37	6.00e-29	120.00
IUUC-Ani-009241	Aspergillus nidulans	26.71	1.00e-24	107.00
IUUC-Ang-009664	Aspergillus niger	28.40	1.00e-23	103.00
IUUC-Ate-010414	Aspergillus terreus	30.23	2.00e-30	125.00
IUUC-Ame-011763	Astyanax mexicanus	88.37	5.00e-139	486.00
IUUC-Bgr-011991	Blumeria graminis	32.23	4.00e-25	108.00
IUUC-Bta-013561	Bos taurus	99.18	2.00e-147	514.00
IUUC-Bci-013824	Botrytis cinerea	32.68	6.00e-31	127.00
IUUC-Bdi-014138	Brachypodium distachyon	43.50	2.00e-61	228.00
IUUC-Bol-016110	Brassica oleracea	43.50	3.00e-57	214.00
IUUC-Bra-016644	Brassica rapa	46.26	9.00e-166	577.00
IUUC-Cel-018441	Caenorhabditis elegans	36.50	1.00e-51	196.00
IUUC-Cja-019502	Callithrix jacchus	99.22	1.00e-155	541.00
IUUC-Cfa-020523	Canis familiaris	99.59	5.00e-148	516.00
IUUC-Cpo-022196	Cavia porcellus	98.45	1.00e-154	538.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	36.50	4.00e-50	191.00
IUUC-Csa-023551	Chlorocebus sabaeus	99.61	3.00e-156	543.00
IUUC-Cho-024373	Choloepus hoffmanni	97.67	8.00e-149	518.00
IUUC-Cin-025269	Ciona intestinalis	61.09	3.00e-100	357.00
IUUC-Csv-026372	Ciona savignyi	42.47	2.00e-51	195.00
IUUC-Cne-026950	Cryptococcus neoformans	31.23	5.00e-30	124.00
IUUC-Dre-028247	Danio rerio	88.37	1.00e-139	488.00
IUUC-Dno-028974	Dasypus novemcinctus	99.61	3.00e-156	543.00
IUUC-Dor-030696	Dipodomys ordii	88.76	5.00e-134	469.00
IUUC-Dse-031365	Dothistroma septosporum	28.19	1.00e-25	109.00
IUUC-Dme-032197	Drosophila melanogaster	63.24	6.00e-94	337.00
IUUC-Ete-032371	Echinops telfairi	99.22	8.00e-156	542.00
IUUC-Eca-033242	Equus caballus	99.61	3.00e-156	543.00
IUUC-Eeu-035317	Erinaceus europaeus	99.22	8.00e-156	542.00
IUUC-Fca-036061	Felis catus	99.61	3.00e-156	544.00
IUUC-Fal-037372	Ficedula albicollis	97.32	5.00e-153	533.00
IUUC-Fox-037884	Fusarium oxysporum	31.76	4.00e-18	84.30
IUUC-Fso-038150	Fusarium solani	28.92	1.00e-20	94.00
IUUC-Gmo-038885	Gadus morhua	87.98	7.00e-139	486.00
IUUC-Gga-040935	Gallus gallus	98.45	7.00e-155	539.00
IUUC-Gac-041937	Gasterosteus aculeatus	87.60	1.00e-137	482.00
IUUC-Gma-043545	Glycine max	42.68	5.00e-58	217.00
IUUC-Ggo-044468	Gorilla gorilla	98.46	7.00e-154	535.00
IUUC-Hsa-046089	Homo sapiens	99.61	3.00e-156	543.00
IUUC-Kpa-049127	Komagataella pastoris	28.52	3.00e-22	98.60
IUUC-Lch-050600	Latimeria chalumnae	94.57	2.00e-150	524.00
IUUC-Lpe-051540	Leersia perrieri	44.18	7.00e-62	230.00
IUUC-Loc-052509	Lepisosteus oculatus	94.96	2.00e-148	518.00
IUUC-Lma-053103	Leptosphaeria maculans	31.18	2.00e-32	132.00
IUUC-Laf-053527	Loxodonta africana	98.84	2.00e-155	541.00
IUUC-Mcc-055699	Macaca mulatta	89.55	2.00e-149	521.00
IUUC-Meu-056626	Macropus eugenii	78.68	1.00e-114	405.00
IUUC-Mor-056909	Magnaporthe oryzae	28.72	5.00e-25	108.00
IUUC-Mpo-057299	Magnaporthe poae	25.00	9.00e-17	80.50
IUUC-Mtr-057964	Medicago truncatula	41.87	2.00e-57	215.00
IUUC-Mla-058990	Melampsora laricipopulina	27.92	1.00e-18	87.00
IUUC-Mga-059379	Meleagris gallopavo	98.71	3.00e-139	487.00
IUUC-Mvi-060312	Microbotryum violaceum	34.23	1.00e-41	163.00
IUUC-Mmr-060851	Microcebus murinus	99.61	5.00e-156	543.00
IUUC-Mmu-063954	Mus musculus	98.84	3.00e-155	540.00
IUUC-Mac-065016	Musa acuminata	44.44	9.00e-44	169.00
IUUC-Mpu-066870	Mustela putorius furo	99.59	5.00e-148	516.00
IUUC-Mlu-067701	Myotis lucifugus	99.22	3.00e-155	540.00
IUUC-Ncr-068780	Neurospora crassa	25.44	2.00e-23	103.00
IUUC-Nle-069291	Nomascus leucogenys	99.61	3.00e-156	543.00
IUUC-Opr-070265	Ochotona princeps	73.26	2.00e-97	348.00
IUUC-Ont-071408	Oreochromis niloticus	88.03	4.00e-138	483.00
IUUC-Oan-073031	Ornithorhynchus anatinus	98.84	1.00e-155	541.00
IUUC-Ocu-074648	Oryctolagus cuniculus	99.61	3.00e-156	543.00
IUUC-Oba-074993	Oryza barthii	44.31	2.00e-61	229.00
IUUC-Obr-076341	Oryza brachyantha	43.90	8.00e-62	229.00
IUUC-Ogl-077099	Oryza glaberrima	44.31	2.00e-61	229.00
IUUC-Ogu-078285	Oryza glumaepatula	43.90	2.00e-60	225.00
IUUC-Oin-079441	Oryza indica	44.31	2.00e-61	229.00
IUUC-Olo-081037	Oryza longistaminata	44.31	2.00e-61	229.00
IUUC-Ome-081357	Oryza meridionalis	44.31	2.00e-61	229.00
IUUC-Oni-082632	Oryza nivara	43.90	2.00e-61	228.00
IUUC-Opu-083351	Oryza punctata	43.97	1.00e-57	215.00
IUUC-Oru-084306	Oryza rufipogon	44.31	2.00e-61	229.00
IUUC-Osa-085307	Oryza sativa	44.31	2.00e-61	229.00
IUUC-Ola-086371	Oryzias latipes	83.40	3.00e-136	477.00
IUUC-Olu-087646	Ostreococcus lucimarinus	36.29	9.00e-45	173.00
IUUC-Oga-089015	Otolemur garnettii	99.22	1.00e-155	541.00
IUUC-Oar-090405	Ovis aries	99.22	1.00e-155	541.00
IUUC-Ptr-090735	Pan troglodytes	99.61	3.00e-156	543.00
IUUC-Pan-092186	Papio anubis	98.84	1.00e-152	531.00
IUUC-Psi-093110	Pelodiscus sinensis	98.77	4.00e-146	509.00
IUUC-Pno-095145	Phaeosphaeria nodorum	33.01	2.00e-25	108.00
IUUC-Ppa-095306	Physcomitrella patens	43.31	2.00e-58	219.00
IUUC-Pfo-096813	Poecilia formosa	83.08	1.00e-134	472.00
IUUC-Pca-100218	Procavia capensis	95.74	3.00e-152	530.00
IUUC-Ppe-102032	Prunus persica	43.95	5.00e-61	227.00
IUUC-Pva-102983	Pteropus vampyrus	93.80	4.00e-141	493.00
IUUC-Pgr-103633	Puccinia graminis	27.21	4.00e-25	108.00
IUUC-Ptt-103979	Puccinia triticina	38.81	3.00e-05	43.10
IUUC-Pyt-104428	Pyrenophora triticirepentis	31.02	5.00e-30	124.00
IUUC-Rno-105554	Rattus norvegicus	98.45	2.00e-155	541.00
IUUC-Sce-106358	Saccharomyces cerevisiae	25.00	2.00e-20	92.40
IUUC-Sha-106888	Sarcophilus harrisii	100.00	1.00e-156	545.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.65	3.00e-24	105.00
IUUC-Spo-108207	Schizosaccharomyces pombe	32.46	9.00e-25	106.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	33.33	2.00e-32	132.00
IUUC-Smo-108750	Selaginella moellendorffii	42.28	7.00e-50	190.00
IUUC-Sit-110052	Setaria italica	43.15	1.00e-61	229.00
IUUC-Sly-111489	Solanum lycopersicum	44.76	4.00e-61	228.00
IUUC-Stu-112517	Solanum tuberosum	43.72	9.00e-60	223.00
IUUC-Sar-113509	Sorex araneus	98.84	2.00e-100	358.00
IUUC-Sbi-114113	Sorghum bicolor	42.80	1.00e-61	229.00
IUUC-Sre-115221	Sporisorium reilianum	27.46	8.00e-26	110.00
IUUC-Ssc-115547	Sus scrofa	99.61	3.00e-156	543.00
IUUC-Tgu-117147	Taeniopygia guttata	98.45	7.00e-155	539.00
IUUC-Tru-117740	Takifugu rubripes	85.33	4.00e-136	476.00
IUUC-Tsy-119599	Tarsius syrichta	99.22	9.00e-156	542.00
IUUC-Tni-120315	Tetraodon nigroviridis	80.86	5.00e-132	463.00
IUUC-Tca-121033	Theobroma cacao	43.90	7.00e-59	220.00
IUUC-Tvi-122607	Trichoderma virens	28.95	1.00e-25	110.00
IUUC-Tae-125740	Triticum aestivum	36.93	2.00e-54	205.00
IUUC-Tur-126375	Triticum urartu	33.65	2.00e-51	196.00
IUUC-Tme-126878	Tuber melanosporum	33.60	2.00e-39	155.00
IUUC-Ttr-129086	Tursiops truncatus	88.76	5.00e-134	469.00
IUUC-Uma-129364	Ustilago maydis	29.70	1.00e-34	139.00
IUUC-Vpa-130048	Vicugna pacos	86.43	4.00e-130	456.00
IUUC-Vvi-130834	Vitis vinifera	44.31	1.00e-59	223.00
IUUC-Xtr-131888	Xenopus tropicalis	97.68	2.00e-154	538.00
IUUC-Xma-133580	Xiphophorus maculatus	83.72	7.00e-136	476.00
IUUC-Zma-135642	Zea mays	44.08	2.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence