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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108207
Ensembl Protein ID SPBC839.03c.1:pep
UniProt Accession Q8WZK4; DCN1_SCHPO
Genbank Protein ID CAB46696.1
Protein Name Defective in cullin neddylation protein 1
Genbank Nucleotide ID CU329671
Gene Name SPBC839.03c; dcn1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPBC839.03c SPBC839.03c.1 SPBC839.03c.1:pep
Annotation
mRNA Expression
GEO
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/DCUN1 33.18 1.00e-21 100.00 IUUC-Ath-007531
E3 activity/DCUN1 32.46 2.00e-23 107.00 IUUC-Hsa-046089
UBD/Alpha-Helix/UBA 32.46 2.00e-23 107.00 IUUC-Hsa-046089
UBD/Alpha-Helix/UBA 32.29 1.00e-23 107.00 IUUC-Mmu-063816
E3 activity/DCUN1 26.90 6.00e-12 65.90 IUUC-Sce-106358
UBD/Alpha-Helix/UBA 26.90 6.00e-12 65.90 IUUC-Sce-106358
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
 May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
Protein Sequence
(Fasta)
MKPDTVSLTR AFSKATSTSS KAALSWLKKY NFDYDVAYTK WIQQKSREEA EKQLNNVFSQ 60
FSSKEDKDLI ELDGSVQLFT ALDISLEDPE TLLVSYFLKS PRMGEFHRES FVEGALNLST 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108207|E3,DCUN1;UBD,UBA|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAAAATGC AACGTAATAG TAAATAAGTA CATTTAAAAG GTAAGAATTT CGAAAAATAA 60
CATTTAAAGT AGACTTGTGA AACTATAGAT TTTAAACTAA CTATTTCCGT TTTCAGATGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108207|E3,DCUN1;UBD,UBA|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
PROSITE

PS51229--DCUN1
Pfam

PF03556--Cullin_binding
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
KEGG spo:SPBC839.03c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000561 Aegilops tauschii 32.51 2.00e-29 120.00
IUUC-Aml-001879 Ailuropoda melanoleuca 31.40 4.00e-28 115.00
IUUC-Atr-002662 Amborella trichopoda 36.56 1.00e-14 71.20
IUUC-Apl-003933 Anas platyrhynchos 29.75 3.00e-25 106.00
IUUC-Aca-005269 Anolis carolinensis 30.99 2.00e-27 114.00
IUUC-Aly-006285 Arabidopsis lyrata 36.36 2.00e-21 93.60
IUUC-Ath-007531 Arabidopsis thaliana 32.64 1.00e-24 104.00
IUUC-Ago-007806 Ashbya gossypii 25.36 1.00e-13 68.20
IUUC-Acl-008172 Aspergillus clavatus 26.24 1.00e-17 81.30
IUUC-Afl-008569 Aspergillus flavus 24.80 2.00e-18 84.00
IUUC-Afu-009005 Aspergillus fumigatus 26.52 4.00e-15 72.40
IUUC-Ani-009241 Aspergillus nidulans 27.08 4.00e-19 86.30
IUUC-Ang-009664 Aspergillus niger 25.25 4.00e-17 79.70
IUUC-Aor-009902 Aspergillus oryzae 27.83 4.00e-08 48.10
IUUC-Ate-010414 Aspergillus terreus 24.80 2.00e-19 87.40
IUUC-Ame-011763 Astyanax mexicanus 29.60 9.00e-27 111.00
IUUC-Bgr-011991 Blumeria graminis 27.86 2.00e-16 77.40
IUUC-Bta-013561 Bos taurus 31.91 8.00e-28 115.00
IUUC-Bci-013824 Botrytis cinerea 27.89 4.00e-22 96.30
IUUC-Bdi-014138 Brachypodium distachyon 32.51 4.00e-29 119.00
IUUC-Bol-016110 Brassica oleracea 33.19 3.00e-26 110.00
IUUC-Bra-017111 Brassica rapa 33.61 2.00e-26 110.00
IUUC-Cel-018441 Caenorhabditis elegans 24.18 2.00e-17 80.50
IUUC-Cja-019502 Callithrix jacchus 31.82 2.00e-28 117.00
IUUC-Cfa-020523 Canis familiaris 31.49 1.00e-27 114.00
IUUC-Cpo-022196 Cavia porcellus 31.82 1.00e-28 117.00
IUUC-Cre-022620 Chlamydomonas reinhardtii 29.75 3.00e-26 110.00
IUUC-Csa-023551 Chlorocebus sabaeus 31.40 3.00e-28 116.00
IUUC-Cho-024417 Choloepus hoffmanni 32.98 1.00e-22 97.10
IUUC-Cin-025269 Ciona intestinalis 29.34 3.00e-26 109.00
IUUC-Csv-025976 Ciona savignyi 23.50 3.00e-15 73.20
IUUC-Cgl-026386 Colletotrichum gloeosporioides 25.84 2.00e-16 76.60
IUUC-Cne-026950 Cryptococcus neoformans 28.52 5.00e-19 85.90
IUUC-Cme-027199 Cyanidioschyzon merolae 37.78 2.70e-02 30.40
IUUC-Dre-028247 Danio rerio 30.29 4.00e-27 112.00
IUUC-Dno-028974 Dasypus novemcinctus 31.40 3.00e-28 116.00
IUUC-Dor-030143 Dipodomys ordii 28.93 5.00e-26 109.00
IUUC-Dse-031365 Dothistroma septosporum 25.10 1.00e-18 84.70
IUUC-Dme-032197 Drosophila melanogaster 29.63 4.00e-26 109.00
IUUC-Ete-032371 Echinops telfairi 31.40 5.00e-28 115.00
IUUC-Eca-033242 Equus caballus 31.40 4.00e-28 116.00
IUUC-Eeu-035317 Erinaceus europaeus 30.99 9.00e-28 115.00
IUUC-Fca-036061 Felis catus 31.40 4.00e-28 116.00
IUUC-Fal-036715 Ficedula albicollis 29.75 2.00e-25 107.00
IUUC-Fox-037884 Fusarium oxysporum 27.27 9.00e-12 61.20
IUUC-Fso-038150 Fusarium solani 30.19 4.00e-17 80.10
IUUC-Gmo-039604 Gadus morhua 34.55 7.00e-26 108.00
IUUC-Ggr-039959 Gaeumannomyces graminis 22.02 1.00e-09 56.20
IUUC-Gga-040224 Gallus gallus 30.17 3.00e-25 106.00
IUUC-Gac-041853 Gasterosteus aculeatus 29.75 1.00e-25 107.00
IUUC-Gma-043516 Glycine max 32.23 1.00e-26 110.00
IUUC-Ggo-044972 Gorilla gorilla 28.93 5.00e-26 109.00
IUUC-Hsa-046089 Homo sapiens 31.40 3.00e-28 116.00
IUUC-Hvu-047636 Hordeum vulgare 31.68 2.00e-10 56.60
IUUC-Itr-047902 Ictidomys tridecemlineatus 28.51 3.00e-25 106.00
IUUC-Kpa-049127 Komagataella pastoris 27.06 9.00e-24 101.00
IUUC-Lch-049751 Latimeria chalumnae 30.99 3.00e-27 113.00
IUUC-Lpe-051540 Leersia perrieri 31.56 9.00e-28 114.00
IUUC-Loc-051976 Lepisosteus oculatus 30.17 5.00e-26 108.00
IUUC-Lma-053103 Leptosphaeria maculans 30.05 1.00e-20 91.30
IUUC-Laf-053527 Loxodonta africana 31.82 2.00e-28 117.00
IUUC-Mcc-054700 Macaca mulatta 29.34 5.00e-26 109.00
IUUC-Meu-056791 Macropus eugenii 38.81 1.00e-18 84.70
IUUC-Mor-056909 Magnaporthe oryzae 23.62 2.00e-14 70.90
IUUC-Mpo-057299 Magnaporthe poae 24.26 6.00e-13 65.90
IUUC-Mtr-057964 Medicago truncatula 31.28 5.00e-26 108.00
IUUC-Mla-058990 Melampsora laricipopulina 25.23 7.00e-11 59.30
IUUC-Mga-060072 Meleagris gallopavo 30.17 4.00e-26 109.00
IUUC-Mvi-060312 Microbotryum violaceum 25.49 1.00e-18 84.30
IUUC-Mmr-060851 Microcebus murinus 31.40 5.00e-28 115.00
IUUC-Mdo-063074 Monodelphis domestica 31.54 8.00e-29 120.00
IUUC-Mmu-063816 Mus musculus 30.17 2.00e-26 110.00
IUUC-Mac-065016 Musa acuminata 36.26 6.00e-25 105.00
IUUC-Mpu-066870 Mustela putorius furo 31.49 1.00e-27 114.00
IUUC-Mlu-067701 Myotis lucifugus 31.40 7.00e-28 115.00
IUUC-Nfi-068610 Neosartorya fischeri 28.00 3.00e-15 72.80
IUUC-Ncr-068780 Neurospora crassa 21.80 1.00e-12 64.70
IUUC-Nle-069291 Nomascus leucogenys 31.40 3.00e-28 116.00
IUUC-Opr-070682 Ochotona princeps 24.75 1.00e-15 74.70
IUUC-Ont-071408 Oreochromis niloticus 31.20 6.00e-28 115.00
IUUC-Oan-073031 Ornithorhynchus anatinus 30.99 8.00e-28 115.00
IUUC-Ocu-074648 Oryctolagus cuniculus 31.40 4.00e-28 116.00
IUUC-Oba-074993 Oryza barthii 32.38 5.00e-29 119.00
IUUC-Obr-076341 Oryza brachyantha 32.38 2.00e-28 117.00
IUUC-Ogl-077099 Oryza glaberrima 32.38 5.00e-29 119.00
IUUC-Ogu-078285 Oryza glumaepatula 31.56 2.00e-27 114.00
IUUC-Oin-079441 Oryza indica 32.38 4.00e-29 119.00
IUUC-Olo-081037 Oryza longistaminata 32.38 4.00e-29 119.00
IUUC-Ome-081357 Oryza meridionalis 32.38 4.00e-29 119.00
IUUC-Oni-082632 Oryza nivara 32.38 5.00e-29 119.00
IUUC-Opu-083351 Oryza punctata 32.91 9.00e-29 118.00
IUUC-Oru-084306 Oryza rufipogon 32.38 4.00e-29 119.00
IUUC-Osa-085307 Oryza sativa 32.38 4.00e-29 119.00
IUUC-Ola-086868 Oryzias latipes 32.79 1.00e-27 114.00
IUUC-Olu-087646 Ostreococcus lucimarinus 31.05 7.00e-20 89.00
IUUC-Oga-089015 Otolemur garnettii 31.82 2.00e-28 117.00
IUUC-Oar-090405 Ovis aries 31.82 2.00e-28 117.00
IUUC-Ptr-090735 Pan troglodytes 31.40 4.00e-28 116.00
IUUC-Pan-092825 Papio anubis 29.34 5.00e-26 109.00
IUUC-Psi-093110 Pelodiscus sinensis 31.49 4.00e-27 112.00
IUUC-Pma-094582 Petromyzon marinus 28.65 8.00e-16 75.10
IUUC-Pno-095145 Phaeosphaeria nodorum 28.36 2.00e-19 87.00
IUUC-Ppa-095306 Physcomitrella patens 30.74 2.00e-27 113.00
IUUC-Pfo-096774 Poecilia formosa 33.07 4.00e-29 119.00
IUUC-Pab-098197 Pongo abelii 31.77 2.00e-25 107.00
IUUC-Pop-098821 Populus trichocarpa 43.14 2.00e-19 85.90
IUUC-Pca-100218 Procavia capensis 31.82 3.00e-28 116.00
IUUC-Ppe-102032 Prunus persica 31.97 2.00e-26 110.00
IUUC-Pva-102691 Pteropus vampyrus 29.34 5.00e-26 109.00
IUUC-Pgr-103633 Puccinia graminis 29.44 3.00e-19 86.70
IUUC-Ptt-103979 Puccinia triticina 25.42 1.00e-03 35.40
IUUC-Pyt-104428 Pyrenophora triticirepentis 28.08 1.00e-21 94.40
IUUC-Rno-105016 Rattus norvegicus 30.99 5.00e-27 112.00
IUUC-Sce-106358 Saccharomyces cerevisiae 26.90 5.00e-13 65.90
IUUC-Sha-106888 Sarcophilus harrisii 31.40 4.00e-28 116.00
IUUC-Sja-107938 Schizosaccharomyces japonicus 56.07 5.00e-79 285.00
IUUC-Ssl-108410 Sclerotinia sclerotiorum 26.77 6.00e-21 92.40
IUUC-Smo-108750 Selaginella moellendorffii 29.17 2.00e-19 87.40
IUUC-Sit-110613 Setaria italica 32.78 4.00e-30 122.00
IUUC-Sly-111489 Solanum lycopersicum 32.38 2.00e-26 110.00
IUUC-Stu-112517 Solanum tuberosum 29.71 5.00e-24 102.00
IUUC-Sar-113248 Sorex araneus 26.87 9.00e-15 71.20
IUUC-Sbi-114082 Sorghum bicolor 32.50 4.00e-29 119.00
IUUC-Sre-115221 Sporisorium reilianum 26.94 3.00e-15 73.60
IUUC-Ssc-115547 Sus scrofa 31.40 3.00e-28 116.00
IUUC-Tgu-117147 Taeniopygia guttata 31.40 2.00e-27 114.00
IUUC-Tru-117740 Takifugu rubripes 32.00 5.00e-29 119.00
IUUC-Tsy-119599 Tarsius syrichta 31.40 4.00e-28 116.00
IUUC-Tni-120315 Tetraodon nigroviridis 28.63 1.00e-23 100.00
IUUC-Tca-121033 Theobroma cacao 32.80 2.00e-26 110.00
IUUC-Tre-121986 Trichoderma reesei 27.67 7.00e-17 79.00
IUUC-Tvi-122607 Trichoderma virens 24.80 3.00e-16 76.60
IUUC-Tae-125740 Triticum aestivum 27.82 2.00e-23 100.00
IUUC-Tur-126375 Triticum urartu 25.32 5.00e-19 86.70
IUUC-Tme-126878 Tuber melanosporum 30.64 3.00e-28 117.00
IUUC-Tbe-127429 Tupaia belangeri 24.88 4.00e-16 76.60
IUUC-Ttr-129086 Tursiops truncatus 27.69 5.00e-20 89.40
IUUC-Uma-129364 Ustilago maydis 30.43 3.00e-23 100.00
IUUC-Vda-129929 Verticillium dahliae 29.19 2.00e-16 78.20
IUUC-Vpa-130543 Vicugna pacos 33.13 8.00e-15 71.60
IUUC-Vvi-130834 Vitis vinifera 32.79 2.00e-26 110.00
IUUC-Xtr-131888 Xenopus tropicalis 30.99 3.00e-27 112.00
IUUC-Xma-134122 Xiphophorus maculatus 30.58 2.00e-27 114.00
IUUC-Yli-134595 Yarrowia lipolytica 31.88 1.00e-29 120.00
IUUC-Zma-135642 Zea mays 32.50 3.00e-29 119.00
Created Date 25-Jun-2017

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