iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001545

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01112004

Gene Name

CDC20; PANDA_015130

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001637.1	ENSAMET00000001805.1	ENSAMEP00000001735.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	5.40e-147	489.0	172	478
E3 adaptor/Cullin RING/DCX/DWD	4.10e-29	99.5	307	336

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL+ssvylwsa++gd+ +l ++ +++d+v+sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDSSVYLWSASSGDILQLLQMeQPGDYVSSVAWIKEGNYLAVGTSNAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarv++L Wn++++ssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTSHSARVSSLCWNSYIVSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAQSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           lkgh+aRvlsl++spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  LKGHTARVLSLTMSPDGATVASAAADETLRLWRCFELDPA 478
           ***********************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAQFVFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPAP SPMRAANRSH SAGRTPGRTP 60
GKSSSKAQTT PSKPGGDRYI PHRSASQMEV ASFLLSKENQ PEDSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCAGT TCGTGTTCGA GAGTGACCTG CACTCGCTGC TGCAGCTGGA CGCACCTATC 60
CCCAATGCAC CTCCGGCGCG CTGGCAGCGC AAAGCTAAGG AAGCCGCGGG GCCGGCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

KEGG

aml:100473900

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	46.33	5.00e-109	388.00
IUUC-Atr-003103	Amborella trichopoda	45.97	2.00e-107	382.00
IUUC-Apl-003255	Anas platyrhynchos	80.73	0.00e+00	749.00
IUUC-Aca-004920	Anolis carolinensis	76.62	0.00e+00	783.00
IUUC-Aly-006303	Arabidopsis lyrata	48.77	4.00e-109	387.00
IUUC-Ath-006795	Arabidopsis thaliana	46.48	4.00e-107	381.00
IUUC-Ate-010479	Aspergillus terreus	49.84	1.00e-90	327.00
IUUC-Ame-010850	Astyanax mexicanus	59.30	2.00e-89	322.00
IUUC-Bgr-012059	Blumeria graminis	48.87	1.00e-93	337.00
IUUC-Bta-012625	Bos taurus	97.19	0.00e+00	948.00
IUUC-Bci-013607	Botrytis cinerea	47.37	4.00e-97	348.00
IUUC-Bdi-014344	Brachypodium distachyon	46.81	4.00e-108	384.00
IUUC-Bol-015368	Brassica oleracea	45.88	5.00e-106	379.00
IUUC-Bra-016738	Brassica rapa	46.60	8.00e-106	377.00
IUUC-Cja-019132	Callithrix jacchus	96.59	0.00e+00	945.00
IUUC-Cfa-020780	Canis familiaris	98.00	0.00e+00	953.00
IUUC-Cpo-022223	Cavia porcellus	96.99	0.00e+00	898.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	49.77	9.00e-117	413.00
IUUC-Csa-023666	Chlorocebus sabaeus	97.39	0.00e+00	945.00
IUUC-Cho-024920	Choloepus hoffmanni	96.45	2.00e-160	559.00
IUUC-Cin-025675	Ciona intestinalis	50.60	9.00e-135	473.00
IUUC-Csv-026019	Ciona savignyi	51.13	9.00e-131	460.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.56	2.00e-95	343.00
IUUC-Cme-027234	Cyanidioschyzon merolae	52.46	4.00e-106	378.00
IUUC-Dre-028026	Danio rerio	58.96	8.00e-180	623.00
IUUC-Dno-028865	Dasypus novemcinctus	96.60	0.00e+00	935.00
IUUC-Dor-030958	Dipodomys ordii	96.59	0.00e+00	945.00
IUUC-Dse-031391	Dothistroma septosporum	48.20	4.00e-95	342.00
IUUC-Dme-031905	Drosophila melanogaster	49.81	2.00e-144	506.00
IUUC-Ete-032387	Echinops telfairi	91.38	0.00e+00	899.00
IUUC-Eca-033522	Equus caballus	87.78	0.00e+00	852.00
IUUC-Eeu-035059	Erinaceus europaeus	84.00	0.00e+00	787.00
IUUC-Fca-036346	Felis catus	98.19	0.00e+00	872.00
IUUC-Fal-037558	Ficedula albicollis	79.17	0.00e+00	790.00
IUUC-Fox-037850	Fusarium oxysporum	46.81	3.00e-96	345.00
IUUC-Fso-038375	Fusarium solani	44.56	8.00e-97	347.00
IUUC-Gmo-039284	Gadus morhua	62.10	0.00e+00	629.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.55	2.00e-98	353.00
IUUC-Gga-040790	Gallus gallus	79.33	0.00e+00	811.00
IUUC-Gac-041431	Gasterosteus aculeatus	61.63	7.00e-180	623.00
IUUC-Gma-043489	Glycine max	46.84	8.00e-107	380.00
IUUC-Ggo-045052	Gorilla gorilla	97.39	0.00e+00	946.00
IUUC-Hsa-046305	Homo sapiens	97.39	0.00e+00	946.00
IUUC-Hvu-047476	Hordeum vulgare	44.90	2.00e-108	385.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	97.80	0.00e+00	904.00
IUUC-Lch-050174	Latimeria chalumnae	61.20	2.00e-173	601.00
IUUC-Lpe-050954	Leersia perrieri	47.14	1.00e-99	357.00
IUUC-Loc-052638	Lepisosteus oculatus	62.72	0.00e+00	632.00
IUUC-Lma-052998	Leptosphaeria maculans	43.05	1.00e-99	357.00
IUUC-Laf-053742	Loxodonta africana	97.60	0.00e+00	946.00
IUUC-Mcc-054948	Macaca mulatta	97.39	0.00e+00	945.00
IUUC-Meu-056013	Macropus eugenii	86.22	4.00e-142	498.00
IUUC-Mor-057277	Magnaporthe oryzae	52.15	6.00e-96	344.00
IUUC-Mpo-057624	Magnaporthe poae	51.47	1.00e-96	347.00
IUUC-Mtr-057725	Medicago truncatula	45.37	2.00e-98	352.00
IUUC-Mga-060102	Meleagris gallopavo	79.56	0.00e+00	812.00
IUUC-Mmr-061615	Microcebus murinus	97.91	0.00e+00	943.00
IUUC-Mdo-061982	Monodelphis domestica	89.34	0.00e+00	778.00
IUUC-Mmu-063864	Mus musculus	94.99	0.00e+00	936.00
IUUC-Mac-064861	Musa acuminata	46.73	2.00e-108	385.00
IUUC-Mpu-066502	Mustela putorius furo	98.80	0.00e+00	950.00
IUUC-Mlu-067277	Myotis lucifugus	89.42	0.00e+00	880.00
IUUC-Ncr-068951	Neurospora crassa	45.33	7.00e-94	338.00
IUUC-Nle-070149	Nomascus leucogenys	97.39	0.00e+00	940.00
IUUC-Opr-070778	Ochotona princeps	95.26	0.00e+00	685.00
IUUC-Ont-071660	Oreochromis niloticus	60.76	7.00e-178	616.00
IUUC-Oan-073677	Ornithorhynchus anatinus	77.29	0.00e+00	704.00
IUUC-Ocu-073797	Oryctolagus cuniculus	96.98	0.00e+00	941.00
IUUC-Oba-075514	Oryza barthii	47.14	2.00e-99	355.00
IUUC-Obr-076018	Oryza brachyantha	45.70	7.00e-107	380.00
IUUC-Ogl-077254	Oryza glaberrima	47.14	6.00e-100	357.00
IUUC-Ogu-078562	Oryza glumaepatula	46.90	3.00e-99	355.00
IUUC-Oin-080094	Oryza indica	47.14	6.00e-100	357.00
IUUC-Olo-080449	Oryza longistaminata	47.14	7.00e-100	357.00
IUUC-Ome-081186	Oryza meridionalis	47.03	3.00e-106	380.00
IUUC-Oni-082243	Oryza nivara	47.14	6.00e-100	357.00
IUUC-Opu-084007	Oryza punctata	47.14	2.00e-99	356.00
IUUC-Oru-084357	Oryza rufipogon	47.14	2.00e-99	356.00
IUUC-Osa-086094	Oryza sativa	47.14	1.00e-99	356.00
IUUC-Ola-086907	Oryzias latipes	60.43	1.00e-165	575.00
IUUC-Olu-087647	Ostreococcus lucimarinus	47.40	2.00e-117	416.00
IUUC-Oga-088184	Otolemur garnettii	96.00	0.00e+00	930.00
IUUC-Oar-090023	Ovis aries	91.68	0.00e+00	839.00
IUUC-Ptr-090935	Pan troglodytes	96.41	0.00e+00	880.00
IUUC-Pan-091845	Papio anubis	97.39	0.00e+00	945.00
IUUC-Psi-093188	Pelodiscus sinensis	79.96	0.00e+00	834.00
IUUC-Pma-094187	Petromyzon marinus	54.36	8.00e-149	520.00
IUUC-Pno-094809	Phaeosphaeria nodorum	41.83	5.00e-100	358.00
IUUC-Ppa-095457	Physcomitrella patens	47.44	5.00e-112	397.00
IUUC-Pfo-097429	Poecilia formosa	58.57	4.00e-161	560.00
IUUC-Pab-098603	Pongo abelii	97.60	0.00e+00	946.00
IUUC-Pop-099654	Populus trichocarpa	45.91	8.00e-102	363.00
IUUC-Pca-101062	Procavia capensis	96.59	0.00e+00	923.00
IUUC-Ppe-101865	Prunus persica	46.30	2.00e-95	342.00
IUUC-Pva-102925	Pteropus vampyrus	95.79	0.00e+00	966.00
IUUC-Pte-104142	Pyrenophora teres	42.20	7.00e-98	351.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	42.04	7.00e-98	351.00
IUUC-Rno-106005	Rattus norvegicus	95.19	0.00e+00	935.00
IUUC-Sha-107472	Sarcophilus harrisii	90.00	0.00e+00	894.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.82	9.00e-94	337.00
IUUC-Spo-108075	Schizosaccharomyces pombe	51.42	6.00e-96	344.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	48.68	2.00e-96	346.00
IUUC-Smo-108922	Selaginella moellendorffii	49.25	5.00e-123	434.00
IUUC-Sit-110732	Setaria italica	46.26	5.00e-108	384.00
IUUC-Sly-111025	Solanum lycopersicum	45.67	5.00e-96	344.00
IUUC-Stu-112676	Solanum tuberosum	45.67	2.00e-97	349.00
IUUC-Sar-113092	Sorex araneus	91.58	0.00e+00	884.00
IUUC-Sbi-114558	Sorghum bicolor	45.13	6.00e-108	384.00
IUUC-Ssc-115710	Sus scrofa	98.20	0.00e+00	952.00
IUUC-Tgu-117100	Taeniopygia guttata	78.17	0.00e+00	788.00
IUUC-Tru-118184	Takifugu rubripes	57.11	2.00e-138	485.00
IUUC-Tsy-118892	Tarsius syrichta	96.81	3.00e-162	563.00
IUUC-Tni-120474	Tetraodon nigroviridis	58.81	7.00e-168	583.00
IUUC-Tca-120949	Theobroma cacao	46.14	9.00e-106	377.00
IUUC-Tre-122211	Trichoderma reesei	40.49	4.00e-96	345.00
IUUC-Tvi-122531	Trichoderma virens	40.84	4.00e-97	348.00
IUUC-Tae-123017	Triticum aestivum	45.13	6.00e-109	387.00
IUUC-Tur-126193	Triticum urartu	45.13	1.00e-108	387.00
IUUC-Tbe-127384	Tupaia belangeri	97.64	8.00e-175	606.00
IUUC-Ttr-128511	Tursiops truncatus	97.60	0.00e+00	946.00
IUUC-Vda-129993	Verticillium dahliae	40.39	2.00e-96	346.00
IUUC-Vvi-131245	Vitis vinifera	46.17	5.00e-94	338.00
IUUC-Xtr-131993	Xenopus tropicalis	72.90	0.00e+00	750.00
IUUC-Xma-133332	Xiphophorus maculatus	61.74	2.00e-177	615.00
IUUC-Zma-135135	Zea mays	46.93	2.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence