iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aly-005657

Ensembl Protein ID

fgenesh1_pm.C_scaffold_4002341

UniProt Accession

D7LDY5; D7LDY5_ARALL

Genbank Protein ID

EFH58316.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

GL348716

Gene Name

ARALYDRAFT_322284

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh1_pm.C_scaffold_4002341	fgenesh1_pm.C_scaffold_4002341	fgenesh1_pm.C_scaffold_4002341

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-25	87.9	79	116
UBD/Beta-Prp	7.50e-49	167.2	34	274

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++   d  +l++Gs D t k+WD+++g++l
   Q: 79   GHNGAVSCCDVsRDsSRLITGSADQTAKLWDVKSGKQL 116
           8***********77799******************987 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlst 83
           l++ h+ ++t + + +d++ll++  +d+t ++w +++g  l ++ gh+++v++++ s+d++ l+tgs D+t+k+wd+++
   Q: 34   LMKGHERPLTFLRYNRDGDLLFSCAKDHTPTLWLAHNGERLGTYRGHNGAVSCCDVSRDSSRLITGSADQTAKLWDVKS 112
           5667888999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..............tlsghdgvvncvvvhpd 148
           gk++ t++   +s++s++fs  gd+l++ + d    v    + + + e                   ++ +n +v+ p 
   Q: 113  GKQLFTFN-FGSSARSVDFSV-GDHLAVITTDHFMGVSSAIHVKRIAEdpqdqvgdsvlvlqSP-DGKKKINRAVWGPL 188
           99999999.999999999999.88888888899999966666666666699999*****86333.3355788999**** PP
   S: 149  gnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsngkelvsgsldgtvk..lwdlqtgecvrtlnghtd 223
           ++ +vsG+ D+++r+Wd +tgkll++   + gh+++++sl    +  ++++gs+d+t k  lwd+++ + +++++    
   Q: 189  NQTIVSGGEDTVIRIWDTETGKLLKQSdvEVGHKEAITSLCKAADDSHFLTGSHDKTAKacLWDMRSLTLIKSYTTVV- 266
           **************************999777*************************99779****999999887643. PP
   S: 224  nvksvrfs 231
           +v+ v++s
   Q: 267  PVNAVAMS 274
           44555555 PP

Organism

Arabidopsis lyrata

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MTMECVNPEG LRLDVRQIQN SSHQTLETRM TPILMKGHER PLTFLRYNRD GDLLFSCAKD 60
HTPTLWLAHN GERLGTYRGH NGAVSCCDVS RDSSRLITGS ADQTAKLWDV KSGKQLFTFN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAATGG AGTGCGTTAA TCCCGAAGGT CTTCGATTAG ATGTTCGCCA AGTATGTATG 60
CATATCTCGC GTATGTTAAA CTTAGCACAA GTTTAGTTCC TTTATACGAT GCTTGTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

aly:ARALYDRAFT_322284

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence