iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fso-038387

Ensembl Protein ID

NechaP69991

UniProt Accession

C7Z8E0; C7Z8E0_NECH7

Genbank Protein ID

EEU39320.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

GG698912

Gene Name

NECHADRAFT_69991

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NechaG69991	NechaT69991	NechaP69991

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.50e-58	198.7	22	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahees 96
           YDRQ+rlw + +q++l+sa++llv  Gag++G+E+lKnLvl G+g +t+ D + v+ ++l+ +F+++++  gks+Ae++ ++l elnp v++e + +s
   Q: 22   YDRQLRLWAASGQAALESANILLVnsGAGTVGVETLKNLVLPGIGRFTIADSAAVTHEDLGVNFFVDDSWLGKSRAEACTNFLLELNPEVEGEWYPKS 119
           ***********************8557999***************************************************************98776 PP
   S: 97   iteleeeiv...FfkkfdvVvlal.dnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd.....dppqktiPfctlketpn.... 181
            ++    ++      kf++++ al  + ++   + +   +++ p+i + + G++++ ++ ++g   + + ++      ++++ +P+++l e+ +    
   Q: 120  QNDFFSLQElltNAPKFTMILYALpLPQDQVQLIHEYASHHKTPTIAVHSVGYYSYFKTTLPGTFPIVDTHPdeaatTDLRLLAPWPELTEFSRemtk 217
           66665555532356689***999835666667799***************************9755555554499999**************775555 PP
   S: 182  .......aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfecdivtk 267
                   ++ +++ +v++ ++le++++ ++++ ++++++k+++++ v++++++      eenfeea+++++k+    + ++  +q+++++++    +
   Q: 218  didnldnHEHGHLPLVVILLHYLEQWQQGHDGAYPTSYADKTAFRKTVSEAMRKdnpeGGEENFEEAVAAVMKHVVVPSLPGsLQQVFDYIHQPH--E 313
           5566655788888888**************************************66655689************988888777*******98855..9 PP
   S: 268  skspfwv....................................................................sfcsnaealq............. 284
           +ks fw+                                                                     fc+na+ ++             
   Q: 314  VKSGFWIiaeavkrfhseqgrlpvpgglpdmkaqssvyiklqniyknqarkdvervlntvrsipggeeidpaqveLFCKNARFIKlingledktvkld 411
           9**************************************************************************99999999998888766666433 PP
   S: 285  ...vpekvekdeevvkasap............lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiep.kldddlikeiagnii 366
              +      ++ ++++ a+            +yl+l a +++ +              +d++++++ + a       + e  + + + + + ag   
   Q: 412  evvE------QQLANDEIAAvagpemplsllpIYLALSATSNVTT-----------AP-ADEIMSFIGQNAPQA---ASNERyQKTAQEVDRAAG--- 485
           3322......33323333225555556544444444433333322...........23.4459*****999643...344443357777777777... PP
   S: 367  paiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
           ++++ ++av gG+aaqE+iK+++++++p++n+ +fd++
   Q: 486  GELHNISAVTGGMAAQEMIKIITKQYVPIDNTCIFDGI 523
           ***********************************986 PP

Organism

Fusarium solani

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MADVMTQTPP VLHGPSEKER KYDRQLRLWA ASGQAALESA NILLVNSGAG TVGVETLKNL 60
VLPGIGRFTI ADSAAVTHED LGVNFFVDDS WLGKSRAEAC TNFLLELNPE VEGEWYPKSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGACG TCATGACCCA GACTCCCCCG GTCCTTCACG GTCCCTCGGA GAAGGAGCGA 60
AAGTATGATC GTCAGCTTCG CTTGTGGGCA GCCTCTGGTC AGGCCGCTCT CGAGTCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

nhe:NECHADRAFT_69991

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	31.89	2.00e-70	258.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.54	2.00e-78	285.00
IUUC-Atr-002644	Amborella trichopoda	32.19	2.00e-58	218.00
IUUC-Apl-003446	Anas platyrhynchos	33.39	3.00e-69	254.00
IUUC-Aca-004450	Anolis carolinensis	34.34	7.00e-79	286.00
IUUC-Aly-005466	Arabidopsis lyrata	32.12	3.00e-66	244.00
IUUC-Ath-006692	Arabidopsis thaliana	32.18	5.00e-67	246.00
IUUC-Ago-007900	Ashbya gossypii	26.24	8.00e-36	142.00
IUUC-Acl-008333	Aspergillus clavatus	44.09	4.00e-124	436.00
IUUC-Afl-008529	Aspergillus flavus	45.15	1.00e-127	447.00
IUUC-Afu-009071	Aspergillus fumigatus	45.71	1.00e-127	448.00
IUUC-Ani-009443	Aspergillus nidulans	43.18	2.00e-119	421.00
IUUC-Ang-009669	Aspergillus niger	45.33	2.00e-137	480.00
IUUC-Aor-009914	Aspergillus oryzae	45.33	1.00e-127	448.00
IUUC-Ate-010450	Aspergillus terreus	44.72	3.00e-128	450.00
IUUC-Ame-011183	Astyanax mexicanus	31.27	1.00e-70	258.00
IUUC-Bgr-012111	Blumeria graminis	51.93	1.00e-149	521.00
IUUC-Bta-012583	Bos taurus	35.03	5.00e-79	286.00
IUUC-Bci-013892	Botrytis cinerea	60.38	1.00e-175	607.00
IUUC-Bdi-014592	Brachypodium distachyon	32.78	3.00e-68	251.00
IUUC-Bol-016399	Brassica oleracea	33.15	1.00e-70	258.00
IUUC-Bra-017506	Brassica rapa	31.37	1.00e-64	239.00
IUUC-Cel-018456	Caenorhabditis elegans	29.06	3.00e-51	194.00
IUUC-Cja-020007	Callithrix jacchus	34.11	9.00e-78	282.00
IUUC-Cfa-020324	Canis familiaris	35.20	1.00e-80	292.00
IUUC-Cpo-022248	Cavia porcellus	33.62	6.00e-44	169.00
IUUC-Csa-023149	Chlorocebus sabaeus	30.71	2.00e-53	201.00
IUUC-Cho-024537	Choloepus hoffmanni	26.88	2.00e-38	151.00
IUUC-Cin-025763	Ciona intestinalis	32.89	2.00e-75	274.00
IUUC-Csv-026113	Ciona savignyi	34.70	1.00e-80	291.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	59.49	1.00e-177	614.00
IUUC-Cne-026884	Cryptococcus neoformans	28.32	2.00e-49	188.00
IUUC-Dre-028140	Danio rerio	33.58	5.00e-75	273.00
IUUC-Dno-030033	Dasypus novemcinctus	37.70	4.00e-71	260.00
IUUC-Dor-030513	Dipodomys ordii	56.19	1.00e-25	109.00
IUUC-Dse-031536	Dothistroma septosporum	41.21	1.00e-118	418.00
IUUC-Dme-031683	Drosophila melanogaster	36.73	1.00e-75	275.00
IUUC-Ete-032420	Echinops telfairi	30.00	3.00e-57	214.00
IUUC-Eca-033992	Equus caballus	30.44	2.00e-50	191.00
IUUC-Eeu-034713	Erinaceus europaeus	57.14	1.00e-26	112.00
IUUC-Fca-036548	Felis catus	34.77	3.00e-79	287.00
IUUC-Fal-037600	Ficedula albicollis	33.21	1.00e-68	252.00
IUUC-Fox-038037	Fusarium oxysporum	82.36	0.00e+00	907.00
IUUC-Gmo-038562	Gadus morhua	32.97	1.00e-70	258.00
IUUC-Ggr-040005	Gaeumannomyces graminis	63.79	0.00e+00	674.00
IUUC-Gga-041129	Gallus gallus	34.85	1.00e-73	268.00
IUUC-Gac-042558	Gasterosteus aculeatus	33.21	5.00e-72	263.00
IUUC-Gma-043221	Glycine max	31.05	7.00e-63	233.00
IUUC-Ggo-045611	Gorilla gorilla	34.58	5.00e-78	283.00
IUUC-Hsa-046563	Homo sapiens	34.77	1.00e-79	288.00
IUUC-Hvu-047790	Hordeum vulgare	31.38	1.00e-41	162.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	34.41	1.00e-77	281.00
IUUC-Kpa-049309	Komagataella pastoris	32.70	3.00e-64	237.00
IUUC-Lch-050038	Latimeria chalumnae	33.33	6.00e-71	259.00
IUUC-Lpe-051535	Leersia perrieri	29.28	2.00e-49	188.00
IUUC-Loc-051917	Lepisosteus oculatus	30.60	7.00e-59	219.00
IUUC-Lma-053112	Leptosphaeria maculans	42.91	1.00e-131	461.00
IUUC-Laf-053690	Loxodonta africana	34.77	3.00e-80	291.00
IUUC-Mcc-055117	Macaca mulatta	33.92	2.00e-75	274.00
IUUC-Meu-056761	Macropus eugenii	28.32	5.00e-49	186.00
IUUC-Mor-057230	Magnaporthe oryzae	63.04	0.00e+00	698.00
IUUC-Mpo-057514	Magnaporthe poae	63.98	0.00e+00	659.00
IUUC-Mtr-058551	Medicago truncatula	31.86	2.00e-61	228.00
IUUC-Mla-059183	Melampsora laricipopulina	33.45	1.00e-73	268.00
IUUC-Mga-060144	Meleagris gallopavo	33.16	7.00e-70	256.00
IUUC-Mvi-060221	Microbotryum violaceum	33.57	2.00e-74	271.00
IUUC-Mmr-061325	Microcebus murinus	33.63	8.00e-76	276.00
IUUC-Mdo-062532	Monodelphis domestica	34.34	2.00e-78	285.00
IUUC-Mmu-063956	Mus musculus	35.05	4.00e-79	286.00
IUUC-Mac-064521	Musa acuminata	33.33	4.00e-70	256.00
IUUC-Mpu-066716	Mustela putorius furo	38.50	5.00e-71	260.00
IUUC-Mlu-067459	Myotis lucifugus	34.77	5.00e-79	286.00
IUUC-Nfi-068245	Neosartorya fischeri	44.83	2.00e-125	441.00
IUUC-Ncr-068910	Neurospora crassa	59.85	0.00e+00	659.00
IUUC-Nle-070034	Nomascus leucogenys	32.79	4.00e-69	253.00
IUUC-Opr-070552	Ochotona princeps	35.68	4.00e-59	220.00
IUUC-Ont-071426	Oreochromis niloticus	34.12	7.00e-75	272.00
IUUC-Oan-073389	Ornithorhynchus anatinus	30.90	3.00e-46	177.00
IUUC-Ocu-074911	Oryctolagus cuniculus	34.95	2.00e-79	287.00
IUUC-Oba-075437	Oryza barthii	32.25	7.00e-60	223.00
IUUC-Obr-076684	Oryza brachyantha	32.04	4.00e-55	207.00
IUUC-Ogl-077170	Oryza glaberrima	32.25	7.00e-60	223.00
IUUC-Ogu-078844	Oryza glumaepatula	30.77	6.00e-51	193.00
IUUC-Oin-079105	Oryza indica	32.25	3.00e-60	224.00
IUUC-Olo-080943	Oryza longistaminata	30.00	4.00e-45	174.00
IUUC-Oni-082891	Oryza nivara	31.34	1.00e-54	206.00
IUUC-Opu-083457	Oryza punctata	32.43	8.00e-60	223.00
IUUC-Oru-084960	Oryza rufipogon	30.04	3.00e-45	174.00
IUUC-Osa-085358	Oryza sativa	32.25	9.00e-60	222.00
IUUC-Ola-086420	Oryzias latipes	32.80	2.00e-46	177.00
IUUC-Olu-087625	Ostreococcus lucimarinus	24.66	1.00e-38	152.00
IUUC-Oga-088810	Otolemur garnettii	35.34	1.00e-79	288.00
IUUC-Oar-089196	Ovis aries	34.84	2.00e-77	281.00
IUUC-Ptr-090617	Pan troglodytes	34.59	7.00e-79	286.00
IUUC-Pan-092761	Papio anubis	34.77	8.00e-80	289.00
IUUC-Psi-093191	Pelodiscus sinensis	32.96	7.00e-70	256.00
IUUC-Pma-094380	Petromyzon marinus	36.27	3.00e-64	237.00
IUUC-Pno-095084	Phaeosphaeria nodorum	40.69	8.00e-115	407.00
IUUC-Ppa-095875	Physcomitrella patens	31.24	1.00e-60	225.00
IUUC-Pfo-096467	Poecilia formosa	33.52	7.00e-71	259.00
IUUC-Pab-098255	Pongo abelii	36.97	1.00e-70	258.00
IUUC-Pop-099722	Populus trichocarpa	32.80	2.00e-68	251.00
IUUC-Pca-100807	Procavia capensis	37.13	1.00e-28	119.00
IUUC-Ppe-101280	Prunus persica	31.83	3.00e-67	247.00
IUUC-Pva-102333	Pteropus vampyrus	33.45	1.00e-70	258.00
IUUC-Pgr-103401	Puccinia graminis	29.08	7.00e-60	223.00
IUUC-Ptt-103889	Puccinia triticina	26.83	7.00e-55	206.00
IUUC-Pte-104355	Pyrenophora teres	42.96	6.00e-130	456.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	42.96	3.00e-128	450.00
IUUC-Rno-105810	Rattus norvegicus	34.53	1.00e-77	282.00
IUUC-Sce-106397	Saccharomyces cerevisiae	24.33	3.00e-26	110.00
IUUC-Sha-106770	Sarcophilus harrisii	40.21	2.00e-50	190.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	32.59	7.00e-67	246.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.90	3.00e-65	241.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	58.54	0.00e+00	626.00
IUUC-Smo-109296	Selaginella moellendorffii	31.03	4.00e-65	240.00
IUUC-Sit-110157	Setaria italica	32.36	8.00e-69	252.00
IUUC-Sly-111105	Solanum lycopersicum	31.46	3.00e-64	237.00
IUUC-Stu-112469	Solanum tuberosum	31.28	5.00e-64	236.00
IUUC-Sar-113083	Sorex araneus	26.20	3.00e-40	157.00
IUUC-Sbi-113813	Sorghum bicolor	31.91	4.00e-68	250.00
IUUC-Sre-115058	Sporisorium reilianum	35.21	2.00e-57	214.00
IUUC-Tgu-116772	Taeniopygia guttata	32.91	2.00e-68	251.00
IUUC-Tru-118686	Takifugu rubripes	34.00	3.00e-76	277.00
IUUC-Tsy-119111	Tarsius syrichta	36.97	3.00e-41	161.00
IUUC-Tni-120231	Tetraodon nigroviridis	31.65	4.00e-64	237.00
IUUC-Tca-121491	Theobroma cacao	31.96	7.00e-61	226.00
IUUC-Tre-122103	Trichoderma reesei	68.54	0.00e+00	764.00
IUUC-Tvi-122672	Trichoderma virens	68.11	0.00e+00	739.00
IUUC-Tae-125316	Triticum aestivum	32.12	2.00e-70	258.00
IUUC-Tur-126487	Triticum urartu	30.95	9.00e-66	242.00
IUUC-Tme-127097	Tuber melanosporum	40.11	6.00e-95	339.00
IUUC-Ttr-128465	Tursiops truncatus	32.91	8.00e-66	243.00
IUUC-Uma-129645	Ustilago maydis	34.71	5.00e-58	217.00
IUUC-Vda-129989	Verticillium dahliae	54.63	2.00e-158	550.00
IUUC-Vpa-130529	Vicugna pacos	33.45	1.00e-70	258.00
IUUC-Vvi-131059	Vitis vinifera	32.19	7.00e-65	239.00
IUUC-Xtr-132002	Xenopus tropicalis	33.89	2.00e-77	281.00
IUUC-Xma-133930	Xiphophorus maculatus	33.83	1.00e-71	262.00
IUUC-Yli-134505	Yarrowia lipolytica	35.37	8.00e-85	305.00
IUUC-Zma-135895	Zea mays	32.08	2.00e-68	251.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence