iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043585

UUCD1 version

UUC-GlM-02895

Ensembl Protein ID

GLYMA12G04290.1

UniProt Accession

I1LPY8; I1LPY8_SOYBN

Genbank Protein ID

KRH24397.1; KRH24398.1; KRH24399.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM000845; CM000845; CM000845

Gene Name

LOC100802600; GLYMA_12G038900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA12G04290	GLYMA12G04290.1	GLYMA12G04290.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.70e-38	128.1	50	86
UBD/Beta-Prp	8.10e-77	259.9	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f ++ +l+vsG+dD +ikvW+++ +++l
   Q: 50   HDGPVRGVHFhNSqPLFVSGGDDYKIKVWNYKMHRCL 86
           99********9777****************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh d++
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHNSQPLFVSGGDDYKIKVWNYKMHRCLFTLLGHLDYI 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................... 166
           ++++f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++++vs+slD+tvr+Wd+                         
   Q: 97   RTVQFHHENPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDIVVSASLDQTVRVWDIgslkrkagppaddvlrlsqmntdlf 189
           *********************************.**************************************************7776666666 PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
               + + + l+g h++ v++ +f+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++++ 
   Q: 190  ggVDAVVKYVLEG-HDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDATKRTG 282
           6333334444466.********************************777668****************************************** PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++t+ +++++++  ++ +++ n l++g  ds   ++kl++++p
   Q: 283  IQTFRREHDRFWILST-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************.6666655555.689999999988765 PP

Organism

Glycine max

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
NSQPLFVSGG DDYKIKVWNY KMHRCLFTLL GHLDYIRTVQ FHHENPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGTATT ACCAAACTTG TCATCAGTGA AAGCCACACT ACTTATAGAA ATTTCATTCC 60
GATCTGTCTC GTTGGTAAAT TAACATAACC ATAGCCAGAT CTCATCTGAA AAGAGAAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

gmx:100802600

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006020	Arabidopsis lyrata	82.03	0.00e+00	2025.00
IUUC-Ath-007360	Arabidopsis thaliana	82.24	0.00e+00	2033.00
IUUC-Bgr-012300	Blumeria graminis	46.84	0.00e+00	1090.00
IUUC-Bci-013781	Botrytis cinerea	47.03	0.00e+00	1115.00
IUUC-Cme-027222	Cyanidioschyzon merolae	40.36	4.00e-146	513.00
IUUC-Mtr-058423	Medicago truncatula	91.34	0.00e+00	2181.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.46	0.00e+00	1070.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence