iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Olu-087822

Ensembl Protein ID

ABO95635

UniProt Accession

A4RWJ6; A4RWJ6_OSTLU

Genbank Protein ID

ABO95635.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CP000584

Gene Name

OSTLU_87099

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OSTLU_87099	ABO95635	ABO95635

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-53	179.9	332	816
UBD/Alpha-Helix/UBA	1.50e-12	45.9	705	742

Active Site

Position(s)	Description	Evidence
341	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
792	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkk.........avsprellkalkkeaeefsgyeq 89
           +GlkN+gNtCY+NSv+Q+L ++p + + +++  k ++ +++p++p +++ +++ kl+++l+   +             av pr++++ ++k ++efs+ +q
   Q: 332  VGLKNMGNTCYLNSVMQVLKQVPAVCDRYFD--KYEIFQSAPEDPVTDFPTQMSKLVNALVsdeY---AspeaenaavAVCPRMFKQLVGKGHPEFSTGRQ 427
           6******************************..788889999******************85541...33344555569********************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..... 185
           qDa E++++lld + ++                       +  +   +   +    F ++++++++c e +nv  ++ + + lsl +p ++ t+k      
   Q: 428  QDAVEYFQHLLDVMTRAE----------------------RAASSRVSAGPPTAAQFTFEIEDKLTCVESGNVRYSTRKDNILSLGIPLDKATNKAsvaaf 506
           ****************99......................3456677788999999******************999999999999999998888899*** PP
   S: 186  .......................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
                                   ++ cLe f ++e++e+   +y++  k+k+ a+k  ++k++P++L ++L R+ +  + + ++k++  v++p++++l++
   Q: 507  kerelkrqkkeeedveeivrpevPFSACLEVFGSTETVED---FYSTALKRKSIASKVARMKTMPNFLAVQLRRY-YVGDDWTPKKLDVLVDVPKTISLEH 603
           ***************************************7...********************************.88889*******************9 PP
   S: 264  fcts..............................................................................................pee 270
             ++                                                                                                 
   Q: 604  LRARglqpgevelpedqdgaametsstpaparvepdmaivsalmsmgfsengskraalatnnastevsmewvfahmedadfneplpdpselpsvsapsA-- 702
           988899999999999988888888888888888888888888888888777777777776666666666666666666666666655555555555550.. PP
   S: 271  kqke....................................................................kkkYeLiavvvHsG.slssGHYvayvkne 302
              +                                                                      +YeL+++++H+G ++++GHYva+v   
   Q: 703  ---VnpesvmmltsmgfgedaaeaalkacagnleraadwlfshaddlqsaiaqvngatndvgtdvdsttldgAGEYELFGIISHMGgNTNCGHYVAHVEI- 799
           ...055555555555555555555566666666666666666666666666666777777777777777777**************************99. PP
   S: 303  kgkWllfdDskVtevkeee 321
           +gkW+ f+D kV  ++  +
   Q: 800  DGKWYIFNDRKVALSR--Q 816
           9***********8774..3 PP

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraannnleaAveyLldg 41
            + +  l++MGF +++a  aL a+ +nle+A+++L+++
   Q: 705  PESVMMLTSMGFGEDAAEAALKACAGNLERAADWLFSH 742
           67788899****************************97 PP

Organism

Ostreococcus lucimarinus

Protein Sequence
(Fasta)

MSARVDDDAL AVCVRAAERG RIARVRDDQT VFKDECAFSF DSPLSAHGVY VNAETLFGYS 60
RKYVALDAAR TGCEVYVRVK TTRTLKPTSE GEAKDETPTT LGFGVDGGFA SESDKYDVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGCGC GCGTCGACGA CGATGCGCTC GCGGTGTGCG TCAGAGCCGC CGAGCGCGGG 60
CGCATCGCGC GCGTGCGCGA CGACCAAACC GTGTTCAAAG ATGAGTGCGC GTTCTCGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

olu:OSTLU_87099

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	40.51	4.00e-155	539.00
IUUC-Aml-002104	Ailuropoda melanoleuca	41.13	0.00e+00	632.00
IUUC-Atr-002580	Amborella trichopoda	38.53	7.00e-161	558.00
IUUC-Apl-003774	Anas platyrhynchos	41.23	2.00e-179	620.00
IUUC-Aca-005368	Anolis carolinensis	42.27	0.00e+00	643.00
IUUC-Aly-005727	Arabidopsis lyrata	40.12	5.00e-165	572.00
IUUC-Ath-006974	Arabidopsis thaliana	39.93	7.00e-166	575.00
IUUC-Ago-007890	Ashbya gossypii	29.52	2.00e-64	238.00
IUUC-Acl-008057	Aspergillus clavatus	31.66	2.00e-92	331.00
IUUC-Afl-008547	Aspergillus flavus	33.38	6.00e-89	319.00
IUUC-Afu-008805	Aspergillus fumigatus	34.48	2.00e-87	314.00
IUUC-Ani-009441	Aspergillus nidulans	29.49	2.00e-77	281.00
IUUC-Ang-009720	Aspergillus niger	30.67	2.00e-87	314.00
IUUC-Aor-010111	Aspergillus oryzae	31.74	4.00e-92	330.00
IUUC-Ate-010531	Aspergillus terreus	30.61	2.00e-80	291.00
IUUC-Ame-011470	Astyanax mexicanus	37.64	2.00e-154	537.00
IUUC-Bgr-012183	Blumeria graminis	30.68	2.00e-90	325.00
IUUC-Bta-013179	Bos taurus	40.78	1.00e-180	624.00
IUUC-Bci-013858	Botrytis cinerea	33.49	1.00e-98	352.00
IUUC-Bdi-014904	Brachypodium distachyon	41.75	3.00e-164	570.00
IUUC-Bol-015296	Brassica oleracea	40.84	5.00e-168	582.00
IUUC-Bra-017939	Brassica rapa	40.46	1.00e-166	577.00
IUUC-Cel-018625	Caenorhabditis elegans	31.70	4.00e-105	373.00
IUUC-Cja-019063	Callithrix jacchus	40.66	0.00e+00	625.00
IUUC-Cfa-020976	Canis familiaris	41.69	0.00e+00	631.00
IUUC-Cpo-022265	Cavia porcellus	41.54	0.00e+00	630.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	47.50	3.00e-151	526.00
IUUC-Csa-024177	Chlorocebus sabaeus	41.82	3.00e-161	559.00
IUUC-Cho-024702	Choloepus hoffmanni	41.81	4.00e-97	346.00
IUUC-Cin-025411	Ciona intestinalis	42.28	7.00e-166	575.00
IUUC-Csv-026347	Ciona savignyi	40.12	6.00e-162	562.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	30.98	9.00e-88	315.00
IUUC-Cne-026831	Cryptococcus neoformans	31.94	1.00e-88	318.00
IUUC-Cme-027335	Cyanidioschyzon merolae	27.46	2.00e-30	125.00
IUUC-Dre-027982	Danio rerio	40.86	1.00e-156	544.00
IUUC-Dno-029034	Dasypus novemcinctus	41.60	0.00e+00	633.00
IUUC-Dor-030479	Dipodomys ordii	44.17	2.00e-83	301.00
IUUC-Dse-031467	Dothistroma septosporum	31.61	1.00e-92	332.00
IUUC-Dme-032075	Drosophila melanogaster	41.70	3.00e-164	569.00
IUUC-Ete-032865	Echinops telfairi	37.96	3.00e-155	540.00
IUUC-Eca-034059	Equus caballus	41.13	0.00e+00	627.00
IUUC-Eeu-035304	Erinaceus europaeus	39.25	1.00e-167	580.00
IUUC-Fca-035515	Felis catus	41.13	0.00e+00	630.00
IUUC-Fal-037271	Ficedula albicollis	42.16	2.00e-174	603.00
IUUC-Fox-037745	Fusarium oxysporum	32.76	1.00e-100	358.00
IUUC-Fso-038158	Fusarium solani	32.89	4.00e-99	353.00
IUUC-Gmo-039071	Gadus morhua	40.45	7.00e-162	561.00
IUUC-Ggr-040098	Gaeumannomyces graminis	30.79	4.00e-91	326.00
IUUC-Gga-040635	Gallus gallus	41.81	0.00e+00	643.00
IUUC-Gac-042528	Gasterosteus aculeatus	40.67	6.00e-160	555.00
IUUC-Gma-043614	Glycine max	39.64	4.00e-156	543.00
IUUC-Ggo-044602	Gorilla gorilla	41.01	0.00e+00	632.00
IUUC-Hsa-045959	Homo sapiens	41.01	0.00e+00	632.00
IUUC-Hvu-047563	Hordeum vulgare	43.77	1.00e-143	501.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	41.15	0.00e+00	631.00
IUUC-Kpa-049156	Komagataella pastoris	29.64	4.00e-88	317.00
IUUC-Lch-049648	Latimeria chalumnae	41.76	2.00e-177	613.00
IUUC-Lpe-051523	Leersia perrieri	41.06	7.00e-166	575.00
IUUC-Loc-052072	Lepisosteus oculatus	38.21	2.00e-155	540.00
IUUC-Lma-053216	Leptosphaeria maculans	33.58	1.00e-94	340.00
IUUC-Laf-054327	Loxodonta africana	40.78	0.00e+00	628.00
IUUC-Mcc-055443	Macaca mulatta	41.25	0.00e+00	634.00
IUUC-Meu-056298	Macropus eugenii	43.20	2.00e-129	454.00
IUUC-Mor-057106	Magnaporthe oryzae	32.10	9.00e-97	345.00
IUUC-Mpo-057589	Magnaporthe poae	31.15	6.00e-91	326.00
IUUC-Mtr-058680	Medicago truncatula	41.08	2.00e-166	577.00
IUUC-Mla-058903	Melampsora laricipopulina	30.33	6.00e-83	299.00
IUUC-Mga-059669	Meleagris gallopavo	41.27	1.00e-176	610.00
IUUC-Mvi-060476	Microbotryum violaceum	32.66	2.00e-93	334.00
IUUC-Mmr-060575	Microcebus murinus	41.01	0.00e+00	630.00
IUUC-Mdo-062183	Monodelphis domestica	42.51	0.00e+00	639.00
IUUC-Mmu-063592	Mus musculus	41.15	0.00e+00	630.00
IUUC-Mac-065634	Musa acuminata	38.48	7.00e-157	545.00
IUUC-Mpu-066082	Mustela putorius furo	42.05	0.00e+00	636.00
IUUC-Mlu-067345	Myotis lucifugus	41.95	0.00e+00	639.00
IUUC-Nfi-068558	Neosartorya fischeri	33.29	2.00e-95	341.00
IUUC-Ncr-068960	Neurospora crassa	31.01	2.00e-92	331.00
IUUC-Nle-070173	Nomascus leucogenys	41.69	0.00e+00	634.00
IUUC-Opr-070556	Ochotona princeps	40.89	0.00e+00	632.00
IUUC-Ont-071502	Oreochromis niloticus	41.25	7.00e-160	555.00
IUUC-Oan-072959	Ornithorhynchus anatinus	43.10	1.00e-51	193.00
IUUC-Ocu-074861	Oryctolagus cuniculus	41.59	0.00e+00	635.00
IUUC-Oba-075109	Oryza barthii	41.29	5.00e-167	578.00
IUUC-Obr-076292	Oryza brachyantha	41.29	3.00e-163	566.00
IUUC-Ogl-077065	Oryza glaberrima	42.27	1.00e-174	604.00
IUUC-Ogu-078776	Oryza glumaepatula	40.93	2.00e-168	583.00
IUUC-Oin-080048	Oryza indica	42.14	3.00e-174	602.00
IUUC-Olo-080711	Oryza longistaminata	40.30	1.00e-154	537.00
IUUC-Ome-081506	Oryza meridionalis	41.30	2.00e-157	546.00
IUUC-Oni-082320	Oryza nivara	40.28	3.00e-163	566.00
IUUC-Opu-083801	Oryza punctata	41.53	6.00e-162	561.00
IUUC-Oru-085139	Oryza rufipogon	40.17	2.00e-162	563.00
IUUC-Osa-085713	Oryza sativa	42.39	8.00e-176	608.00
IUUC-Ola-086951	Oryzias latipes	39.37	1.00e-152	531.00
IUUC-Oga-088625	Otolemur garnettii	41.06	0.00e+00	632.00
IUUC-Oar-089995	Ovis aries	40.73	0.00e+00	630.00
IUUC-Ptr-090640	Pan troglodytes	40.66	0.00e+00	630.00
IUUC-Pan-091974	Papio anubis	41.36	0.00e+00	638.00
IUUC-Psi-093957	Pelodiscus sinensis	41.83	0.00e+00	656.00
IUUC-Pma-094242	Petromyzon marinus	45.31	3.00e-95	339.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.20	8.00e-91	325.00
IUUC-Ppa-095901	Physcomitrella patens	40.45	1.00e-170	590.00
IUUC-Pfo-097148	Poecilia formosa	41.98	3.00e-160	556.00
IUUC-Pab-098068	Pongo abelii	38.52	7.00e-158	548.00
IUUC-Pop-098943	Populus trichocarpa	40.24	1.00e-158	551.00
IUUC-Pca-100738	Procavia capensis	41.31	1.00e-131	461.00
IUUC-Ppe-101315	Prunus persica	40.89	1.00e-160	557.00
IUUC-Pva-102154	Pteropus vampyrus	40.80	3.00e-180	622.00
IUUC-Pgr-103343	Puccinia graminis	31.92	3.00e-79	286.00
IUUC-Ptt-103928	Puccinia triticina	30.39	7.00e-78	282.00
IUUC-Pte-104306	Pyrenophora teres	31.42	3.00e-87	313.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	31.42	1.00e-91	328.00
IUUC-Rno-105801	Rattus norvegicus	41.27	0.00e+00	633.00
IUUC-Sce-106304	Saccharomyces cerevisiae	28.31	6.00e-60	223.00
IUUC-Sha-107635	Sarcophilus harrisii	42.53	0.00e+00	633.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	32.31	2.00e-78	284.00
IUUC-Spo-108144	Schizosaccharomyces pombe	32.42	2.00e-78	284.00
IUUC-Smo-108848	Selaginella moellendorffii	41.04	1.00e-163	567.00
IUUC-Sit-110728	Setaria italica	41.53	3.00e-177	612.00
IUUC-Sly-111523	Solanum lycopersicum	40.14	2.00e-171	593.00
IUUC-Sar-113733	Sorex araneus	36.98	2.00e-68	251.00
IUUC-Sbi-114419	Sorghum bicolor	42.02	1.00e-173	600.00
IUUC-Sre-115225	Sporisorium reilianum	33.37	4.00e-92	330.00
IUUC-Ssc-115686	Sus scrofa	41.38	0.00e+00	632.00
IUUC-Tgu-117346	Taeniopygia guttata	41.88	1.00e-180	624.00
IUUC-Tru-118350	Takifugu rubripes	39.67	4.00e-162	562.00
IUUC-Tsy-119278	Tarsius syrichta	34.69	8.00e-127	445.00
IUUC-Tni-120658	Tetraodon nigroviridis	40.07	9.00e-156	541.00
IUUC-Tca-121585	Theobroma cacao	39.45	9.00e-156	541.00
IUUC-Tre-122043	Trichoderma reesei	31.88	1.00e-92	332.00
IUUC-Tvi-122303	Trichoderma virens	30.92	2.00e-95	341.00
IUUC-Tae-125686	Triticum aestivum	42.50	7.00e-172	595.00
IUUC-Tur-126732	Triticum urartu	40.02	2.00e-159	553.00
IUUC-Tme-126909	Tuber melanosporum	32.86	9.00e-91	325.00
IUUC-Tbe-127261	Tupaia belangeri	37.36	7.00e-108	382.00
IUUC-Ttr-129119	Tursiops truncatus	44.66	6.00e-84	303.00
IUUC-Uma-129599	Ustilago maydis	32.84	1.00e-99	355.00
IUUC-Vda-129688	Verticillium dahliae	31.29	8.00e-94	335.00
IUUC-Vpa-130170	Vicugna pacos	32.85	3.00e-113	400.00
IUUC-Vvi-131116	Vitis vinifera	40.26	4.00e-156	543.00
IUUC-Xtr-131953	Xenopus tropicalis	39.79	2.00e-165	573.00
IUUC-Xma-133837	Xiphophorus maculatus	41.86	7.00e-160	555.00
IUUC-Yli-134510	Yarrowia lipolytica	32.51	6.00e-91	326.00
IUUC-Zma-135786	Zea mays	40.88	2.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence