iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049565

Ensembl Protein ID

ENSLACP00000007856.1

UniProt Accession

H3ADY5; H3ADY5_LATCH

Genbank Protein ID

ENSLACP00000007856

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01217718

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000006956.1	ENSLACT00000007922.1	ENSLACP00000007856.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.90e-131	437.7	13	418

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 14   eklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitelee 102
           ++++ +++l+vGagg+GcEllKnLvl+G+++i v+D dt++vsnlnrqFLf++++vgksKA+va+e++ +++p  n++a+++si+++++
   Q: 13   DSVSACRALVVGAGGIGCELLKNLVLTGFSNIDVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLQFCPEANITAYHDSIMNPDY 101
           567899*********************************************************************************** PP
   S: 103  eivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa. 190
           +++Ff+kf++V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv+vi kg+tecy+c+++p+qk++P+ct+++tp+++ h+i+wa 
   Q: 102  NVEFFRKFTLVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTVIKKGVTECYECQPKPTQKSFPGCTIRNTPSEPIHCIVWAk 190
           ***************************************************************************************** PP
   S: 191  vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv.... 274
           +lfn+l++ee++++ev+++  ++++e+++++  +++++ ++e++  ++++++ka+ak+t ++ +k + k f++di++  ++++++    
   Q: 191  YLFNQLFGEEDADQEVSPD--TADPEAAWEPMNAAARTVESEEDGSIKRVSTKAWAKSTGYDpVKLFNKLFKDDIRYLLTMDKLWrkrk 277
           ******************5..68**************************************************************9999 PP
   S: 275  ...........sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraesl 347
                      +++  +  +++ ++++kd++v++ +++     +++++++l ++ek +     el ++kdd+ a+d+vtaaanlr++ +
   Q: 278  pptpldwfevqNLERGELHIESFQTGLKDQQVLDLKSYaqlfsKSVETLKLLLAEKGDAA---ELIWDKDDPPAMDFVTAAANLRMHIF 363
           99999988666555666666678**********999999995555555555555555555...89************************ PP
   S: 348  giepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           ++++  ++++ik++agniipaiattnav++Gl+++E +Kv+sg  ++++++fl+++
   Q: 364  SMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKVLSGNLDQCRTIFLNKQ 418
           ****.***********************************************9965 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MALAGALSKL LADSVSACRA LVVGAGGIGC ELLKNLVLTG FSNIDVIDLD TIDVSNLNRQ 60
FLFQKKHVGK SKAQVAKESV LQFCPEANIT AYHDSIMNPD YNVEFFRKFT LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTATTATT TTCTTTTTGT TTCTTTTGTT TATTTTTGTG CTTTTTTTTT TTTTAAATCC 60
TCCGGAAGAT TGAGGTGTTT TTGCCCTGTG CGTCGCTGGT GTTTTTCCGC CTGCCTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

KEGG

lcm:102366922

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.51	5.00e-109	388.00
IUUC-Aml-001662	Ailuropoda melanoleuca	82.90	0.00e+00	1017.00
IUUC-Atr-002636	Amborella trichopoda	41.44	2.00e-111	396.00
IUUC-Apl-003369	Anas platyrhynchos	82.46	0.00e+00	927.00
IUUC-Aca-004490	Anolis carolinensis	78.51	0.00e+00	851.00
IUUC-Aly-006359	Arabidopsis lyrata	41.80	7.00e-103	367.00
IUUC-Ath-007667	Arabidopsis thaliana	42.00	1.00e-106	380.00
IUUC-Ago-007844	Ashbya gossypii	35.56	9.00e-82	297.00
IUUC-Acl-008270	Aspergillus clavatus	44.28	7.00e-106	377.00
IUUC-Afl-008674	Aspergillus flavus	44.15	2.00e-113	402.00
IUUC-Afu-008883	Aspergillus fumigatus	40.73	9.00e-108	384.00
IUUC-Ani-009500	Aspergillus nidulans	46.42	1.00e-116	413.00
IUUC-Ang-009535	Aspergillus niger	43.67	4.00e-111	395.00
IUUC-Aor-010223	Aspergillus oryzae	44.26	2.00e-113	402.00
IUUC-Ate-010282	Aspergillus terreus	44.52	5.00e-90	325.00
IUUC-Ame-011736	Astyanax mexicanus	79.72	0.00e+00	1009.00
IUUC-Bgr-012166	Blumeria graminis	43.46	3.00e-101	362.00
IUUC-Bta-012589	Bos taurus	82.43	0.00e+00	1031.00
IUUC-Bci-013802	Botrytis cinerea	44.68	1.00e-103	370.00
IUUC-Bdi-014697	Brachypodium distachyon	41.39	1.00e-112	400.00
IUUC-Bol-016315	Brassica oleracea	41.14	4.00e-107	382.00
IUUC-Bra-017009	Brassica rapa	38.34	6.00e-108	384.00
IUUC-Cel-018708	Caenorhabditis elegans	47.44	3.00e-131	462.00
IUUC-Cja-019120	Callithrix jacchus	82.43	0.00e+00	1001.00
IUUC-Cfa-021061	Canis familiaris	81.80	0.00e+00	1027.00
IUUC-Cpo-021842	Cavia porcellus	81.80	0.00e+00	994.00
IUUC-Csa-024104	Chlorocebus sabaeus	82.14	0.00e+00	976.00
IUUC-Cho-024332	Choloepus hoffmanni	76.53	0.00e+00	749.00
IUUC-Cin-025363	Ciona intestinalis	62.04	0.00e+00	692.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	43.91	6.00e-100	358.00
IUUC-Cne-026888	Cryptococcus neoformans	53.33	3.00e-74	273.00
IUUC-Cme-027315	Cyanidioschyzon merolae	32.24	2.00e-60	226.00
IUUC-Dre-028420	Danio rerio	78.08	0.00e+00	951.00
IUUC-Dno-030041	Dasypus novemcinctus	81.83	0.00e+00	991.00
IUUC-Dor-031039	Dipodomys ordii	67.14	9.00e-145	506.00
IUUC-Dse-031504	Dothistroma septosporum	40.50	2.00e-96	346.00
IUUC-Dme-031771	Drosophila melanogaster	52.72	3.00e-147	515.00
IUUC-Ete-033037	Echinops telfairi	77.31	0.00e+00	887.00
IUUC-Eca-033774	Equus caballus	83.25	0.00e+00	1000.00
IUUC-Eeu-035074	Erinaceus europaeus	80.32	0.00e+00	789.00
IUUC-Fca-036508	Felis catus	83.25	0.00e+00	1001.00
IUUC-Fal-036813	Ficedula albicollis	81.69	0.00e+00	942.00
IUUC-Fox-038056	Fusarium oxysporum	44.55	1.00e-106	380.00
IUUC-Fso-038223	Fusarium solani	45.27	1.00e-105	377.00
IUUC-Gmo-038526	Gadus morhua	80.07	0.00e+00	904.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.69	3.00e-99	355.00
IUUC-Gga-040981	Gallus gallus	81.41	0.00e+00	950.00
IUUC-Gac-041437	Gasterosteus aculeatus	75.52	0.00e+00	930.00
IUUC-Gma-044072	Glycine max	38.33	1.00e-113	403.00
IUUC-Ggo-045358	Gorilla gorilla	79.01	0.00e+00	924.00
IUUC-Hsa-046068	Homo sapiens	82.27	0.00e+00	981.00
IUUC-Hvu-047646	Hordeum vulgare	40.81	3.00e-109	389.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	82.14	0.00e+00	998.00
IUUC-Lpe-050884	Leersia perrieri	41.14	3.00e-109	389.00
IUUC-Loc-052493	Lepisosteus oculatus	81.66	0.00e+00	1018.00
IUUC-Lma-053117	Leptosphaeria maculans	46.61	1.00e-105	377.00
IUUC-Laf-054518	Loxodonta africana	79.81	0.00e+00	984.00
IUUC-Mcc-055334	Macaca mulatta	81.80	0.00e+00	978.00
IUUC-Mor-057137	Magnaporthe oryzae	44.58	2.00e-96	346.00
IUUC-Mpo-057449	Magnaporthe poae	42.78	8.00e-101	361.00
IUUC-Mtr-058045	Medicago truncatula	38.70	5.00e-117	414.00
IUUC-Mla-058864	Melampsora laricipopulina	45.36	2.00e-95	343.00
IUUC-Mga-059422	Meleagris gallopavo	76.76	0.00e+00	833.00
IUUC-Mvi-060536	Microbotryum violaceum	39.97	2.00e-86	313.00
IUUC-Mmr-061161	Microcebus murinus	80.76	0.00e+00	991.00
IUUC-Mdo-061802	Monodelphis domestica	83.12	0.00e+00	1003.00
IUUC-Mmu-064357	Mus musculus	82.53	0.00e+00	1030.00
IUUC-Mac-065475	Musa acuminata	41.36	8.00e-113	400.00
IUUC-Mpu-066895	Mustela putorius furo	82.12	0.00e+00	1028.00
IUUC-Mlu-067862	Myotis lucifugus	81.83	0.00e+00	1026.00
IUUC-Nfi-068385	Neosartorya fischeri	42.99	3.00e-109	388.00
IUUC-Ncr-068885	Neurospora crassa	45.68	9.00e-108	384.00
IUUC-Nle-069524	Nomascus leucogenys	81.62	0.00e+00	966.00
IUUC-Opr-071038	Ochotona princeps	82.09	0.00e+00	1030.00
IUUC-Ont-071719	Oreochromis niloticus	78.41	0.00e+00	985.00
IUUC-Oan-072877	Ornithorhynchus anatinus	83.14	0.00e+00	892.00
IUUC-Ocu-074080	Oryctolagus cuniculus	81.96	0.00e+00	995.00
IUUC-Oba-075936	Oryza barthii	40.84	3.00e-110	392.00
IUUC-Obr-076841	Oryza brachyantha	40.73	3.00e-111	395.00
IUUC-Ogl-077686	Oryza glaberrima	40.76	2.00e-111	396.00
IUUC-Ogu-078597	Oryza glumaepatula	39.75	5.00e-107	381.00
IUUC-Oin-079791	Oryza indica	40.84	3.00e-110	392.00
IUUC-Olo-081009	Oryza longistaminata	40.84	3.00e-110	392.00
IUUC-Ome-081327	Oryza meridionalis	37.80	9.00e-104	370.00
IUUC-Oni-082334	Oryza nivara	39.96	1.00e-107	384.00
IUUC-Opu-083447	Oryza punctata	40.55	2.00e-111	396.00
IUUC-Oru-084977	Oryza rufipogon	40.84	4.00e-110	391.00
IUUC-Osa-086160	Oryza sativa	45.21	2.00e-96	346.00
IUUC-Ola-087415	Oryzias latipes	77.81	0.00e+00	950.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.18	8.00e-98	350.00
IUUC-Oga-088434	Otolemur garnettii	81.80	0.00e+00	995.00
IUUC-Oar-089872	Ovis aries	83.28	0.00e+00	994.00
IUUC-Ptr-091212	Pan troglodytes	82.27	0.00e+00	981.00
IUUC-Pan-092708	Papio anubis	85.71	8.00e-118	417.00
IUUC-Psi-093703	Pelodiscus sinensis	84.15	0.00e+00	951.00
IUUC-Pno-094953	Phaeosphaeria nodorum	48.72	5.00e-107	381.00
IUUC-Ppa-095963	Physcomitrella patens	42.28	8.00e-106	377.00
IUUC-Pfo-097515	Poecilia formosa	77.50	0.00e+00	937.00
IUUC-Pab-097951	Pongo abelii	82.27	0.00e+00	849.00
IUUC-Pop-099703	Populus trichocarpa	37.21	3.00e-95	342.00
IUUC-Pca-100426	Procavia capensis	80.87	0.00e+00	1014.00
IUUC-Ppe-101152	Prunus persica	40.87	5.00e-111	395.00
IUUC-Pva-102792	Pteropus vampyrus	78.89	0.00e+00	956.00
IUUC-Pgr-103592	Puccinia graminis	43.94	2.00e-100	359.00
IUUC-Ptt-103805	Puccinia triticina	41.68	2.00e-82	300.00
IUUC-Pte-104215	Pyrenophora teres	46.04	2.00e-113	402.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	43.96	9.00e-113	400.00
IUUC-Rno-106117	Rattus norvegicus	82.19	0.00e+00	1026.00
IUUC-Sce-106177	Saccharomyces cerevisiae	37.25	2.00e-72	266.00
IUUC-Sha-107006	Sarcophilus harrisii	82.87	0.00e+00	1001.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.35	7.00e-95	341.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.42	5.00e-95	341.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	45.89	9.00e-106	377.00
IUUC-Smo-109264	Selaginella moellendorffii	43.65	4.00e-108	385.00
IUUC-Sit-110581	Setaria italica	41.86	4.00e-113	402.00
IUUC-Sly-111870	Solanum lycopersicum	37.22	5.00e-109	388.00
IUUC-Stu-112283	Solanum tuberosum	40.36	5.00e-108	384.00
IUUC-Sar-113432	Sorex araneus	60.56	0.00e+00	658.00
IUUC-Sbi-114075	Sorghum bicolor	41.61	3.00e-112	399.00
IUUC-Sre-114926	Sporisorium reilianum	43.09	8.00e-104	371.00
IUUC-Ssc-116281	Sus scrofa	87.61	3.00e-106	377.00
IUUC-Tgu-117247	Taeniopygia guttata	81.57	0.00e+00	938.00
IUUC-Tru-118075	Takifugu rubripes	74.44	0.00e+00	899.00
IUUC-Tsy-119398	Tarsius syrichta	67.65	0.00e+00	738.00
IUUC-Tni-120771	Tetraodon nigroviridis	68.00	0.00e+00	815.00
IUUC-Tca-121651	Theobroma cacao	40.18	8.00e-109	387.00
IUUC-Tre-122224	Trichoderma reesei	44.26	3.00e-97	349.00
IUUC-Tvi-122634	Trichoderma virens	44.92	7.00e-100	357.00
IUUC-Tae-125665	Triticum aestivum	41.76	1.00e-107	383.00
IUUC-Tur-126417	Triticum urartu	40.61	2.00e-108	386.00
IUUC-Tme-127016	Tuber melanosporum	47.59	2.00e-99	356.00
IUUC-Tbe-127678	Tupaia belangeri	81.02	5.00e-131	461.00
IUUC-Ttr-128598	Tursiops truncatus	78.07	0.00e+00	968.00
IUUC-Uma-129612	Ustilago maydis	41.35	1.00e-95	344.00
IUUC-Vda-129811	Verticillium dahliae	44.99	6.00e-103	368.00
IUUC-Vpa-130732	Vicugna pacos	68.43	0.00e+00	809.00
IUUC-Vvi-130832	Vitis vinifera	41.25	1.00e-108	387.00
IUUC-Xtr-132823	Xenopus tropicalis	75.46	0.00e+00	903.00
IUUC-Xma-133552	Xiphophorus maculatus	77.02	0.00e+00	934.00
IUUC-Yli-134666	Yarrowia lipolytica	39.26	4.00e-78	285.00
IUUC-Zma-135547	Zea mays	40.99	1.00e-111	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence