iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065540

Ensembl Protein ID

GSMUA_Achr3P30340_001

UniProt Accession

M0SJ48; M0SJ48_MUSAM

Protein Name

Ribosome biogenesis protein WDR12 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr3G30340_001	GSMUA_Achr3T30340_001	GSMUA_Achr3P30340_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-36	122.2	283	317
UBD/Beta-Prp	8.90e-42	144.1	279	438

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgv 34
           gH+ sv+++ +++ +++ s+s+D++++ WD+ tg 
   Q: 283  GHSQSVSSIVWPErKTIYSASWDHSVRQWDVQTGQ 317
           8**********88899***************9986 PP

UBD/Beta-Prp

   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllr 173
           +tl gh++sv s+ + + ++++ s+s+d  +r wd++tgq+    +    +v nc+ + +++  l+++G+ D ++r+Wd  k g+l  
   Q: 279  STLIGHSQSVSSIVWPE-RKTIYSASWDHSVRQWDVQTGQET--WNMACGKVLNCLDIGGESsALIAAGGSDPILRIWDPrKPGTLAP 363
           7899*********9977.************************..69*********************************965566666 PP
   S: 174  tl..tgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
            +  ++ h + +   +++ ++ ++l+s+s+dg+v lwdl+t   + +   h++ v++ + + +++ ++sg++D  + 
   Q: 364  VFqfSS-HSSWISACKWHCKSwFHLLSASYDGKVMLWDLRTAWPLAIIDSHKEKVLCADWW-KNDSVISGGADSKLL 438
           665477.9999*******9999***************************************.777788999998765 PP

Organism

Musa acuminata

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MDFGVAGGAG GSEEAARRVR VRFTTKLGPP LRVPSAPLAV PSNLTRMGLS EIVNLLLENA 60
SAEHETQPFD FLIDGELVRL PLEEFLLAKG ISAEKVLEIE YIKAVAPRKQ QDPRLHDDWV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTTCG GCGTAGCTGG CGGCGCGGGT GGTAGCGAGG AGGCCGCGCG GCGAGTCCGC 60
GTGCGGTTCA CCACCAAGCT CGGGCCGCCG CTCCGAGTCC CCTCCGCCCC CCTTGCCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0009506--C:plasmodesma
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000532	Aegilops tauschii	71.06	0.00e+00	643.00
IUUC-Aml-001997	Ailuropoda melanoleuca	34.72	6.00e-54	204.00
IUUC-Atr-002544	Amborella trichopoda	63.66	6.00e-161	559.00
IUUC-Apl-003981	Anas platyrhynchos	33.33	3.00e-51	195.00
IUUC-Aca-004370	Anolis carolinensis	31.99	7.00e-60	223.00
IUUC-Aly-006455	Arabidopsis lyrata	63.28	1.00e-168	585.00
IUUC-Ath-006669	Arabidopsis thaliana	63.28	7.00e-165	572.00
IUUC-Ago-007864	Ashbya gossypii	31.41	3.00e-48	185.00
IUUC-Acl-008177	Aspergillus clavatus	29.62	1.00e-40	160.00
IUUC-Afl-008617	Aspergillus flavus	29.57	7.00e-37	147.00
IUUC-Afu-008752	Aspergillus fumigatus	29.16	4.00e-38	152.00
IUUC-Ani-009136	Aspergillus nidulans	30.20	9.00e-40	157.00
IUUC-Ang-009701	Aspergillus niger	28.86	2.00e-35	143.00
IUUC-Aor-009884	Aspergillus oryzae	29.81	4.00e-38	151.00
IUUC-Ame-011432	Astyanax mexicanus	31.99	3.00e-63	235.00
IUUC-Bgr-012218	Blumeria graminis	28.98	1.00e-35	143.00
IUUC-Bta-012829	Bos taurus	33.25	3.00e-54	205.00
IUUC-Bci-013953	Botrytis cinerea	28.88	2.00e-37	149.00
IUUC-Bdi-014351	Brachypodium distachyon	70.37	1.00e-178	618.00
IUUC-Bol-016514	Brassica oleracea	61.93	7.00e-154	536.00
IUUC-Bra-016988	Brassica rapa	62.16	3.00e-154	537.00
IUUC-Cel-018569	Caenorhabditis elegans	24.36	1.00e-24	106.00
IUUC-Cja-019468	Callithrix jacchus	33.73	2.00e-53	202.00
IUUC-Cfa-020471	Canis familiaris	33.57	3.00e-54	205.00
IUUC-Cpo-022260	Cavia porcellus	34.43	3.00e-54	205.00
IUUC-Cre-022614	Chlamydomonas reinhardtii	38.12	1.00e-61	229.00
IUUC-Csa-023989	Chlorocebus sabaeus	33.49	2.00e-53	202.00
IUUC-Cho-024426	Choloepus hoffmanni	31.79	2.00e-39	155.00
IUUC-Cin-025789	Ciona intestinalis	29.88	6.00e-50	191.00
IUUC-Cne-027063	Cryptococcus neoformans	27.63	1.00e-28	120.00
IUUC-Dre-027907	Danio rerio	33.41	3.00e-64	238.00
IUUC-Dno-029225	Dasypus novemcinctus	33.25	1.00e-55	209.00
IUUC-Dor-031082	Dipodomys ordii	33.19	3.00e-25	108.00
IUUC-Dse-031308	Dothistroma septosporum	31.59	8.00e-47	180.00
IUUC-Dme-032189	Drosophila melanogaster	30.66	3.00e-48	185.00
IUUC-Ete-032247	Echinops telfairi	32.31	6.00e-48	184.00
IUUC-Eca-034285	Equus caballus	33.96	1.00e-54	206.00
IUUC-Eeu-035322	Erinaceus europaeus	28.29	1.00e-42	166.00
IUUC-Fca-036114	Felis catus	33.96	4.00e-54	204.00
IUUC-Fal-036891	Ficedula albicollis	32.15	4.00e-44	171.00
IUUC-Fox-037965	Fusarium oxysporum	25.89	4.00e-30	125.00
IUUC-Fso-038244	Fusarium solani	24.51	1.00e-28	120.00
IUUC-Gmo-039040	Gadus morhua	31.99	1.00e-62	233.00
IUUC-Ggr-040093	Gaeumannomyces graminis	24.83	4.00e-26	112.00
IUUC-Gga-040610	Gallus gallus	32.78	9.00e-56	210.00
IUUC-Gac-042117	Gasterosteus aculeatus	32.71	4.00e-62	231.00
IUUC-Gma-043967	Glycine max	63.59	9.00e-170	588.00
IUUC-Ggo-045179	Gorilla gorilla	34.20	5.00e-53	201.00
IUUC-Hsa-046114	Homo sapiens	34.43	3.00e-53	202.00
IUUC-Hvu-047331	Hordeum vulgare	71.43	9.00e-166	575.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	34.20	5.00e-55	207.00
IUUC-Kpa-049304	Komagataella pastoris	30.19	3.00e-44	172.00
IUUC-Lch-050655	Latimeria chalumnae	29.97	9.00e-40	156.00
IUUC-Lpe-051675	Leersia perrieri	70.94	0.00e+00	654.00
IUUC-Loc-052868	Lepisosteus oculatus	33.26	6.00e-61	227.00
IUUC-Lma-053258	Leptosphaeria maculans	30.48	6.00e-39	156.00
IUUC-Laf-053993	Loxodonta africana	33.96	3.00e-55	208.00
IUUC-Mcc-055128	Macaca mulatta	26.13	5.00e-33	134.00
IUUC-Meu-056501	Macropus eugenii	33.04	1.00e-43	169.00
IUUC-Mor-057114	Magnaporthe oryzae	27.59	1.00e-38	153.00
IUUC-Mpo-057463	Magnaporthe poae	36.81	4.00e-18	84.00
IUUC-Mtr-058367	Medicago truncatula	61.75	7.00e-158	549.00
IUUC-Mla-059107	Melampsora laricipopulina	29.05	4.00e-38	151.00
IUUC-Mga-059745	Meleagris gallopavo	32.85	3.00e-54	205.00
IUUC-Mvi-060362	Microbotryum violaceum	24.78	7.00e-29	121.00
IUUC-Mdo-062257	Monodelphis domestica	31.76	2.00e-56	212.00
IUUC-Mmu-063546	Mus musculus	33.18	6.00e-55	207.00
IUUC-Mpu-066284	Mustela putorius furo	33.96	7.00e-55	207.00
IUUC-Mlu-067241	Myotis lucifugus	33.57	5.00e-56	211.00
IUUC-Nfi-068260	Neosartorya fischeri	29.40	2.00e-39	156.00
IUUC-Ncr-068719	Neurospora crassa	26.73	7.00e-35	140.00
IUUC-Nle-068981	Nomascus leucogenys	34.67	2.00e-54	206.00
IUUC-Opr-071218	Ochotona princeps	32.35	7.00e-51	194.00
IUUC-Ont-071646	Oreochromis niloticus	32.70	2.00e-56	212.00
IUUC-Oan-073453	Ornithorhynchus anatinus	33.26	1.00e-61	229.00
IUUC-Ocu-074008	Oryctolagus cuniculus	34.20	4.00e-55	207.00
IUUC-Oba-075712	Oryza barthii	59.72	1.00e-144	505.00
IUUC-Obr-076721	Oryza brachyantha	70.71	0.00e+00	650.00
IUUC-Ogl-077229	Oryza glaberrima	69.79	0.00e+00	642.00
IUUC-Ogu-078977	Oryza glumaepatula	60.19	5.00e-146	510.00
IUUC-Oin-079683	Oryza indica	70.25	0.00e+00	645.00
IUUC-Olo-080291	Oryza longistaminata	61.64	3.00e-106	377.00
IUUC-Ome-081834	Oryza meridionalis	71.33	0.00e+00	641.00
IUUC-Oni-082507	Oryza nivara	67.73	5.00e-176	609.00
IUUC-Opu-083396	Oryza punctata	71.10	0.00e+00	651.00
IUUC-Oru-085220	Oryza rufipogon	67.96	2.00e-176	611.00
IUUC-Osa-085767	Oryza sativa	70.25	0.00e+00	645.00
IUUC-Ola-087420	Oryzias latipes	33.02	2.00e-66	245.00
IUUC-Olu-087740	Ostreococcus lucimarinus	30.44	2.00e-53	202.00
IUUC-Oga-088264	Otolemur garnettii	33.49	2.00e-54	206.00
IUUC-Oar-089335	Ovis aries	33.49	9.00e-55	206.00
IUUC-Ptr-091320	Pan troglodytes	34.43	3.00e-53	202.00
IUUC-Pan-092833	Papio anubis	33.25	4.00e-53	201.00
IUUC-Psi-093504	Pelodiscus sinensis	31.06	2.00e-50	192.00
IUUC-Pma-094189	Petromyzon marinus	32.47	2.00e-57	216.00
IUUC-Pno-094929	Phaeosphaeria nodorum	29.47	5.00e-39	154.00
IUUC-Ppa-095429	Physcomitrella patens	52.68	1.00e-126	445.00
IUUC-Pfo-096337	Poecilia formosa	33.65	4.00e-64	238.00
IUUC-Pab-097571	Pongo abelii	34.20	3.00e-53	201.00
IUUC-Pop-099977	Populus trichocarpa	66.59	1.00e-172	598.00
IUUC-Pca-100394	Procavia capensis	32.76	6.00e-47	180.00
IUUC-Ppe-101848	Prunus persica	61.70	6.00e-166	576.00
IUUC-Pva-102921	Pteropus vampyrus	30.97	4.00e-24	105.00
IUUC-Pgr-103637	Puccinia graminis	28.60	6.00e-40	157.00
IUUC-Ptt-103781	Puccinia triticina	27.78	2.00e-39	156.00
IUUC-Pte-104135	Pyrenophora teres	29.98	6.00e-37	149.00
IUUC-Pyt-104609	Pyrenophora triticirepentis	30.49	3.00e-39	155.00
IUUC-Rno-105114	Rattus norvegicus	33.72	4.00e-55	207.00
IUUC-Sce-106401	Saccharomyces cerevisiae	31.12	1.00e-45	176.00
IUUC-Sha-107122	Sarcophilus harrisii	33.96	2.00e-57	216.00
IUUC-Sja-107766	Schizosaccharomyces japonicus	29.37	2.00e-43	169.00
IUUC-Spo-108134	Schizosaccharomyces pombe	29.16	2.00e-37	149.00
IUUC-Ssl-108398	Sclerotinia sclerotiorum	28.83	3.00e-42	165.00
IUUC-Smo-108720	Selaginella moellendorffii	48.26	1.00e-115	409.00
IUUC-Sit-110354	Setaria italica	70.14	0.00e+00	639.00
IUUC-Sly-111023	Solanum lycopersicum	59.49	2.00e-156	544.00
IUUC-Stu-112778	Solanum tuberosum	64.91	1.00e-164	572.00
IUUC-Sar-113596	Sorex araneus	29.74	4.00e-39	155.00
IUUC-Sbi-114193	Sorghum bicolor	69.68	9.00e-175	605.00
IUUC-Sre-115002	Sporisorium reilianum	29.86	6.00e-20	91.70
IUUC-Ssc-116066	Sus scrofa	33.49	4.00e-54	204.00
IUUC-Tgu-117048	Taeniopygia guttata	33.07	5.00e-51	194.00
IUUC-Tni-119820	Tetraodon nigroviridis	34.20	5.00e-61	228.00
IUUC-Tca-121605	Theobroma cacao	65.67	6.00e-173	599.00
IUUC-Tre-121947	Trichoderma reesei	25.16	1.00e-31	130.00
IUUC-Tvi-122481	Trichoderma virens	25.73	6.00e-31	127.00
IUUC-Tae-123504	Triticum aestivum	71.06	0.00e+00	643.00
IUUC-Tur-126586	Triticum urartu	71.93	9.00e-173	598.00
IUUC-Tme-126900	Tuber melanosporum	32.37	7.00e-54	204.00
IUUC-Tbe-127736	Tupaia belangeri	32.37	2.00e-19	89.40
IUUC-Ttr-129041	Tursiops truncatus	29.41	8.00e-38	150.00
IUUC-Uma-129628	Ustilago maydis	24.03	6.00e-14	71.60
IUUC-Vpa-130260	Vicugna pacos	33.73	8.00e-55	207.00
IUUC-Vvi-131009	Vitis vinifera	68.42	0.00e+00	630.00
IUUC-Xtr-132083	Xenopus tropicalis	34.12	6.00e-59	220.00
IUUC-Xma-133094	Xiphophorus maculatus	32.54	4.00e-63	234.00
IUUC-Yli-134531	Yarrowia lipolytica	27.31	8.00e-32	130.00
IUUC-Zma-135509	Zea mays	69.28	0.00e+00	634.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence