iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059337

UUCD1 version

UUC-MeG-00065

Ensembl Protein ID

ENSMGAP00000000775.1

UniProt Accession

G1MRG5; G1MRG5_MELGA

Protein Name

Uncharacterized protein

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000001311.1	ENSMGAT00000001421.1	ENSMGAP00000000775.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-43	142.8	211	247
UBD/Beta-Prp	4.70e-64	216.1	306	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 211  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 247
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
           +p  ++l+t srd+t ++wdv+t+  +++lsgh+++v++vk++  ++  vtgs D ti++wdl +gk+ +tl++h++sv+++ ++p  +
   Q: 306  HPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVKCQAAEPQVVTGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVILHPRHY 394
           67778999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 108  klvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.......tgghtdsvyslsfd 189
           +++sGs d+ i+ w+ + g  ++  lsgh++++n+++v++ + +lvsG++++t+ lWd +tg   ++        + + ++ +    fd
   Q: 395  TFASGSPDN-IKQWKFPDGNFIQ-NLSGHNAIINTLTVNS-DGVLVSGADNGTMHLWDWRTGYNFQRVhaavqpgSLDSESGIFACVFD 480
           999999665.9999999999999.9999999999999999.678999999999999999999988888765555533345555555599 PP
   S: 190  sngkelvsgsldgtvklwd 208
           ++  +l+++  d+t+k++ 
   Q: 481  QSESRLLTAEADKTIKVYK 499
           9999999999999999996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

CRPAELGKYK EVQKHSVHTL VFRSLKRTHD MFVADNAKPV PLDDESHKVK MAVKLRTEYG 60
SVLHMPTLKE NMREKGGPAT GDPYGHKQYS GNEGEELEYV ITGTHPYPPG PGVALTADTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGGCCTG CTGAGTTAGG GAAATATAAA GTGTGGCAGA ATGGGTCGAT AAGTGGGCAA 60
ACAGAGTTCA GGGTAGGAAA CCCCAGTTTA TGGAACATGG AGGCGGGACA GCTGAATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	46.45	1.00e-128	452.00
IUUC-Aml-001605	Ailuropoda melanoleuca	89.88	0.00e+00	971.00
IUUC-Atr-002757	Amborella trichopoda	49.39	5.00e-132	464.00
IUUC-Apl-003198	Anas platyrhynchos	97.08	0.00e+00	1048.00
IUUC-Aca-004683	Anolis carolinensis	90.66	0.00e+00	988.00
IUUC-Aly-005775	Arabidopsis lyrata	54.52	8.00e-125	439.00
IUUC-Ath-007460	Arabidopsis thaliana	60.96	4.00e-124	437.00
IUUC-Ago-007884	Ashbya gossypii	49.43	2.00e-106	378.00
IUUC-Acl-008153	Aspergillus clavatus	63.72	3.00e-128	451.00
IUUC-Afl-008384	Aspergillus flavus	60.27	2.00e-129	455.00
IUUC-Afu-009045	Aspergillus fumigatus	64.33	3.00e-129	454.00
IUUC-Ani-009229	Aspergillus nidulans	62.68	3.00e-129	454.00
IUUC-Ang-009812	Aspergillus niger	64.98	1.00e-123	435.00
IUUC-Aor-010059	Aspergillus oryzae	60.27	2.00e-129	455.00
IUUC-Ate-010351	Aspergillus terreus	64.33	5.00e-135	473.00
IUUC-Ame-011613	Astyanax mexicanus	60.29	5.00e-164	570.00
IUUC-Bgr-012042	Blumeria graminis	56.15	1.00e-134	472.00
IUUC-Bta-012406	Bos taurus	88.72	0.00e+00	952.00
IUUC-Bci-013760	Botrytis cinerea	59.47	2.00e-134	472.00
IUUC-Bdi-014776	Brachypodium distachyon	49.58	2.00e-130	458.00
IUUC-Bol-016189	Brassica oleracea	60.96	6.00e-125	440.00
IUUC-Bra-018044	Brassica rapa	60.96	8.00e-125	440.00
IUUC-Cel-018651	Caenorhabditis elegans	52.48	6.00e-154	536.00
IUUC-Cja-019974	Callithrix jacchus	88.72	0.00e+00	956.00
IUUC-Cfa-021085	Canis familiaris	89.88	0.00e+00	972.00
IUUC-Cpo-021458	Cavia porcellus	88.72	0.00e+00	962.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.88	7.00e-124	436.00
IUUC-Csa-023883	Chlorocebus sabaeus	88.52	0.00e+00	952.00
IUUC-Cho-024623	Choloepus hoffmanni	89.17	0.00e+00	946.00
IUUC-Cin-025190	Ciona intestinalis	61.48	0.00e+00	649.00
IUUC-Csv-026367	Ciona savignyi	59.92	0.00e+00	646.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	56.42	1.00e-139	489.00
IUUC-Cne-027069	Cryptococcus neoformans	48.05	1.00e-126	446.00
IUUC-Cme-027233	Cyanidioschyzon merolae	29.57	1.00e-34	140.00
IUUC-Dre-028260	Danio rerio	81.91	0.00e+00	884.00
IUUC-Dno-029112	Dasypus novemcinctus	89.49	0.00e+00	966.00
IUUC-Dor-031118	Dipodomys ordii	90.75	0.00e+00	780.00
IUUC-Dse-031493	Dothistroma septosporum	46.00	1.00e-125	442.00
IUUC-Dme-032138	Drosophila melanogaster	76.00	3.00e-159	554.00
IUUC-Ete-032411	Echinops telfairi	79.34	0.00e+00	779.00
IUUC-Eca-033521	Equus caballus	89.30	0.00e+00	972.00
IUUC-Eeu-035249	Erinaceus europaeus	79.08	0.00e+00	657.00
IUUC-Fca-036358	Felis catus	89.11	0.00e+00	964.00
IUUC-Fal-036933	Ficedula albicollis	94.75	0.00e+00	1028.00
IUUC-Fox-037713	Fusarium oxysporum	65.34	4.00e-138	484.00
IUUC-Fso-038380	Fusarium solani	63.74	3.00e-138	484.00
IUUC-Gmo-039133	Gadus morhua	82.26	0.00e+00	891.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.97	1.00e-132	466.00
IUUC-Gga-041176	Gallus gallus	98.64	0.00e+00	1055.00
IUUC-Gac-042344	Gasterosteus aculeatus	78.79	0.00e+00	865.00
IUUC-Gma-043328	Glycine max	48.88	1.00e-130	459.00
IUUC-Ggo-044478	Gorilla gorilla	88.89	0.00e+00	954.00
IUUC-Hsa-046037	Homo sapiens	88.52	0.00e+00	952.00
IUUC-Hvu-047349	Hordeum vulgare	50.00	5.00e-132	464.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	89.11	0.00e+00	965.00
IUUC-Kpa-049343	Komagataella pastoris	58.46	6.00e-119	420.00
IUUC-Lch-049830	Latimeria chalumnae	85.60	0.00e+00	927.00
IUUC-Lpe-051442	Leersia perrieri	48.47	2.00e-129	455.00
IUUC-Loc-051794	Lepisosteus oculatus	84.04	0.00e+00	892.00
IUUC-Lma-053137	Leptosphaeria maculans	45.54	4.00e-127	447.00
IUUC-Laf-053471	Loxodonta africana	88.54	0.00e+00	964.00
IUUC-Mcc-055627	Macaca mulatta	88.72	0.00e+00	956.00
IUUC-Meu-056148	Macropus eugenii	79.53	0.00e+00	849.00
IUUC-Mor-056960	Magnaporthe oryzae	66.56	4.00e-137	481.00
IUUC-Mtr-057816	Medicago truncatula	47.55	3.00e-127	448.00
IUUC-Mla-059031	Melampsora laricipopulina	65.72	5.00e-127	446.00
IUUC-Mvi-060217	Microbotryum violaceum	64.69	7.00e-130	457.00
IUUC-Mmr-061018	Microcebus murinus	89.49	0.00e+00	968.00
IUUC-Mdo-062863	Monodelphis domestica	91.25	0.00e+00	973.00
IUUC-Mmu-063988	Mus musculus	87.35	0.00e+00	939.00
IUUC-Mac-064459	Musa acuminata	48.99	2.00e-123	435.00
IUUC-Mpu-066559	Mustela putorius furo	90.08	0.00e+00	973.00
IUUC-Mlu-067361	Myotis lucifugus	89.47	0.00e+00	946.00
IUUC-Nfi-068492	Neosartorya fischeri	64.63	2.00e-129	455.00
IUUC-Ncr-068808	Neurospora crassa	57.21	7.00e-137	480.00
IUUC-Nle-069875	Nomascus leucogenys	88.72	0.00e+00	954.00
IUUC-Opr-070462	Ochotona princeps	95.86	6.00e-156	543.00
IUUC-Ont-071365	Oreochromis niloticus	78.99	0.00e+00	872.00
IUUC-Oan-072708	Ornithorhynchus anatinus	91.63	0.00e+00	1000.00
IUUC-Ocu-074594	Oryctolagus cuniculus	88.91	0.00e+00	961.00
IUUC-Oba-075570	Oryza barthii	60.97	8.00e-127	446.00
IUUC-Obr-076366	Oryza brachyantha	65.25	6.00e-92	329.00
IUUC-Ogl-077153	Oryza glaberrima	60.97	5.00e-126	444.00
IUUC-Ogu-078540	Oryza glumaepatula	60.97	1.00e-126	446.00
IUUC-Oin-079612	Oryza indica	60.11	8.00e-125	439.00
IUUC-Olo-081077	Oryza longistaminata	60.11	8.00e-125	439.00
IUUC-Ome-081236	Oryza meridionalis	62.13	2.00e-124	438.00
IUUC-Oni-082499	Oryza nivara	60.97	1.00e-126	446.00
IUUC-Opu-083499	Oryza punctata	60.11	1.00e-124	439.00
IUUC-Oru-084276	Oryza rufipogon	60.97	1.00e-126	446.00
IUUC-Osa-085849	Oryza sativa	60.97	1.00e-126	446.00
IUUC-Ola-086655	Oryzias latipes	76.63	0.00e+00	841.00
IUUC-Olu-087637	Ostreococcus lucimarinus	57.60	7.00e-120	423.00
IUUC-Oga-087934	Otolemur garnettii	89.32	0.00e+00	964.00
IUUC-Oar-090185	Ovis aries	88.74	0.00e+00	950.00
IUUC-Ptr-091198	Pan troglodytes	88.72	0.00e+00	954.00
IUUC-Pan-092622	Papio anubis	88.52	0.00e+00	952.00
IUUC-Psi-093320	Pelodiscus sinensis	92.23	0.00e+00	1007.00
IUUC-Pma-094638	Petromyzon marinus	78.64	0.00e+00	863.00
IUUC-Pno-094826	Phaeosphaeria nodorum	51.32	7.00e-106	377.00
IUUC-Ppa-095576	Physcomitrella patens	65.59	3.00e-125	441.00
IUUC-Pfo-096894	Poecilia formosa	78.88	0.00e+00	857.00
IUUC-Pab-098020	Pongo abelii	88.72	0.00e+00	955.00
IUUC-Pop-099180	Populus trichocarpa	48.55	1.00e-126	446.00
IUUC-Pca-100909	Procavia capensis	84.09	0.00e+00	760.00
IUUC-Ppe-101346	Prunus persica	46.18	1.00e-125	442.00
IUUC-Pva-102167	Pteropus vampyrus	74.85	0.00e+00	759.00
IUUC-Pgr-103516	Puccinia graminis	49.59	1.00e-130	459.00
IUUC-Ptt-103738	Puccinia triticina	50.00	3.00e-130	457.00
IUUC-Pte-104352	Pyrenophora teres	59.00	3.00e-131	461.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	59.59	4.00e-132	464.00
IUUC-Rno-105291	Rattus norvegicus	87.94	0.00e+00	948.00
IUUC-Sce-106204	Saccharomyces cerevisiae	50.76	1.00e-103	369.00
IUUC-Sha-106943	Sarcophilus harrisii	90.87	0.00e+00	966.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	64.31	5.00e-130	457.00
IUUC-Spo-108049	Schizosaccharomyces pombe	63.74	7.00e-136	476.00
IUUC-Smo-109043	Selaginella moellendorffii	61.38	5.00e-125	440.00
IUUC-Sit-110431	Setaria italica	51.15	6.00e-131	460.00
IUUC-Sly-111391	Solanum lycopersicum	62.30	4.00e-119	421.00
IUUC-Stu-112364	Solanum tuberosum	56.25	2.00e-96	345.00
IUUC-Sar-113450	Sorex araneus	95.70	0.00e+00	711.00
IUUC-Sbi-113829	Sorghum bicolor	50.00	2.00e-131	461.00
IUUC-Sre-115153	Sporisorium reilianum	60.78	2.00e-122	431.00
IUUC-Ssc-116274	Sus scrofa	88.74	0.00e+00	962.00
IUUC-Tgu-117417	Taeniopygia guttata	95.13	0.00e+00	1034.00
IUUC-Tru-117615	Takifugu rubripes	74.95	0.00e+00	808.00
IUUC-Tsy-119480	Tarsius syrichta	89.47	0.00e+00	961.00
IUUC-Tni-119847	Tetraodon nigroviridis	76.41	0.00e+00	832.00
IUUC-Tca-121287	Theobroma cacao	47.56	1.00e-129	456.00
IUUC-Tre-122010	Trichoderma reesei	65.79	9.00e-143	499.00
IUUC-Tvi-122475	Trichoderma virens	67.18	2.00e-141	495.00
IUUC-Tae-124243	Triticum aestivum	50.10	7.00e-133	466.00
IUUC-Tur-126116	Triticum urartu	41.65	4.00e-100	357.00
IUUC-Tbe-127803	Tupaia belangeri	80.19	0.00e+00	703.00
IUUC-Ttr-128933	Tursiops truncatus	89.47	0.00e+00	962.00
IUUC-Uma-129447	Ustilago maydis	59.38	2.00e-117	415.00
IUUC-Vda-129780	Verticillium dahliae	63.82	3.00e-137	481.00
IUUC-Vpa-130557	Vicugna pacos	78.51	6.00e-102	364.00
IUUC-Vvi-130918	Vitis vinifera	47.35	3.00e-121	428.00
IUUC-Xtr-132409	Xenopus tropicalis	87.31	0.00e+00	913.00
IUUC-Xma-133420	Xiphophorus maculatus	78.29	0.00e+00	858.00
IUUC-Yli-134362	Yarrowia lipolytica	59.15	7.00e-121	426.00
IUUC-Zma-135804	Zea mays	60.11	6.00e-125	440.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence