iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047565

Ensembl Protein ID

MLOC_4843.1

UniProt Accession

M0WCD8; M0WCD8_HORVV

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_4843	MLOC_4843.1	MLOC_4843.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	4.00e-124	414.9	143	452
E3 adaptor/Cullin RING/DCX/DWD	2.60e-23	82.2	278	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltg.hsa 97
           e+ ldap+l dd+ylnL+dW+s+nvl++aL  ++ylw+a++g+ s+l  + e++  +tsvsw ++g +la+G +++ ++++D+++++ +rtl+g h +
   Q: 143  ERTLDAPDLVDDYYLNLMDWGSSNVLSIALSDTMYLWDASSGSTSELVTVeEDNGPITSVSWAPDGRHLAIGLNSSDIQLWDTSSNRLLRTLKGvHES 240
           689***********************************************666779************************************664899 PP
   S: 98   rvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.........Plkkfkehkaavkaia 186
           rvg+L+Wn++vl++G+ dg+i+ +dvr++++ ++++q+h+qevCGlkw+ ++++LasGGnDn +++wd s  +          l++ ++h+aavka+a
   Q: 241  RVGSLAWNNNVLTTGGMDGRIVNNDVRIRDHAVQMYQGHSQEVCGLKWSGSGQQLASGGNDNLLHIWDVSMASsmpsagrnqWLHRLEDHTAAVKALA 338
           ********************************************************************98777676666666688999********** PP
   S: 187  wsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivt 284
           w+P+q++lLa+GGG +Drcikfwnt tga+l+++dtgsqvcsllw k+++el+s+hGf++n++tlwkyps+ k+ael+gh++Rvl +a spdg ++++
   Q: 339  WCPFQSNLLATGGGGSDRCIKFWNTHTGACLNSVDTGSQVCSLLWNKNERELLSSHGFTQNQLTLWKYPSMVKMAELTGHTSRVLFMAQSPDGCTVAS 436
           ************************************************************************************************** PP
   S: 285  aagDetlrfwklfdkk 300
           aa+Detlrfw++f + 
   Q: 437  AAADETLRFWNVFGTP 452
           *************865 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH+ +v++l++  s+  l+sG++D+ +++WD+
   Q: 278  GHSQEVCGLKWsgSGQQLASGGNDNLLHIWDV 309
           8**********976699**************8 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MDAGSHSISS SKSSAAAVQR PPLQEAGSRP YMPPLSTTSR NPSAKCYGDR FIPDRSAMDM 60
DMAHYLLTET KKDKENAAAI AASPSKEAYR RLLAEKLLNN RTRILAFRNK PPEPENVFAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGGTAGA TGAGAATCAT CAATGCACTA AAAGTGTGTA AACTTTCTTC GTACCATCAT 60
ATGATTTGCA ACCACAGACG TCGTGGCGGA ATACTATGAT ATATTTAATT GATACCAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	98.25	0.00e+00	924.00
IUUC-Aly-006253	Arabidopsis lyrata	70.90	0.00e+00	661.00
IUUC-Ath-006795	Arabidopsis thaliana	71.12	0.00e+00	662.00
IUUC-Bol-015368	Brassica oleracea	74.07	0.00e+00	664.00
IUUC-Bra-016738	Brassica rapa	72.71	0.00e+00	661.00
IUUC-Cho-024920	Choloepus hoffmanni	66.67	2.00e-43	168.00
IUUC-Cme-027234	Cyanidioschyzon merolae	46.58	1.00e-98	352.00
IUUC-Dno-028865	Dasypus novemcinctus	45.64	5.00e-104	370.00
IUUC-Dse-031391	Dothistroma septosporum	48.40	2.00e-95	342.00
IUUC-Ete-032387	Echinops telfairi	43.42	2.00e-96	345.00
IUUC-Fal-037558	Ficedula albicollis	47.57	6.00e-107	380.00
IUUC-Gga-040790	Gallus gallus	47.57	3.00e-108	384.00
IUUC-Gma-043985	Glycine max	73.10	0.00e+00	626.00
IUUC-Mtr-057725	Medicago truncatula	72.57	0.00e+00	635.00
IUUC-Mga-060102	Meleagris gallopavo	47.82	2.00e-108	385.00
IUUC-Mac-064861	Musa acuminata	82.02	0.00e+00	780.00
IUUC-Oan-073677	Ornithorhynchus anatinus	52.68	3.00e-97	347.00
IUUC-Ocu-073797	Oryctolagus cuniculus	47.48	1.00e-107	382.00
IUUC-Obr-076018	Oryza brachyantha	86.01	0.00e+00	840.00
IUUC-Ome-081186	Oryza meridionalis	85.32	0.00e+00	827.00
IUUC-Olu-087647	Ostreococcus lucimarinus	56.19	2.00e-135	474.00
IUUC-Ppa-095687	Physcomitrella patens	62.28	2.00e-155	541.00
IUUC-Pop-099654	Populus trichocarpa	73.72	0.00e+00	653.00
IUUC-Pca-101062	Procavia capensis	47.14	3.00e-107	380.00
IUUC-Ppe-101865	Prunus persica	75.59	0.00e+00	633.00
IUUC-Sit-110032	Setaria italica	90.13	0.00e+00	846.00
IUUC-Sly-111202	Solanum lycopersicum	78.16	0.00e+00	661.00
IUUC-Stu-112676	Solanum tuberosum	77.75	0.00e+00	652.00
IUUC-Sbi-114558	Sorghum bicolor	89.26	0.00e+00	843.00
IUUC-Tsy-118931	Tarsius syrichta	37.34	3.00e-56	211.00
IUUC-Tca-120949	Theobroma cacao	78.07	0.00e+00	678.00
IUUC-Tae-123918	Triticum aestivum	97.89	0.00e+00	929.00
IUUC-Tme-126905	Tuber melanosporum	48.65	9.00e-96	343.00
IUUC-Ttr-128511	Tursiops truncatus	47.25	3.00e-107	380.00
IUUC-Vvi-131245	Vitis vinifera	79.01	0.00e+00	629.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence