iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094187

UUCD1 version

UUC-PeM-00002

Ensembl Protein ID

ENSPMAP00000002836.1

UniProt Accession

S4RCA4; S4RCA4_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000002592.1	ENSPMAT00000002850.1	ENSPMAP00000002836.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-22	78.3	311	341
E3 adaptor/Cullin RING/APC_C/CDC20	7.90e-124	412.1	175	480

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+ +v++la+ ++ +ll+sGs+D+++ vW 
   Q: 311  GHSQEVCGLAWsPGgRLLASGSNDNNLLVWA 341
           8***********8889**************5 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgs.svylwsaktgdvskladleekdlvtsvswiee.gtllavGtkkgeveiyDveekk 87
           pe+vldap +r+dfyln ldWs +nv+ vaLg+   ylw+a+tg+v++ +++e +d+ +svsw+++ g+++a+Gt++ +v+i+Dve++k
   Q: 175  PERVLDAPAVRNDFYLNPLDWSVDNVVCVALGQfGTYLWDAETGNVTQHMKMEGQDYPSSVSWVPTgGNIIAIGTSFKTVQIWDVERNK 263
           689****************************98369****************************9735899****************** PP
   S: 88   kvrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse..Plkk 174
           ++r+++ghs rv++LsWn ++lssGsr+g+i+h+dvr+ +++++tl++h+qevCGl w+  ++lLasG nDn++ vw + +++  Pl++
   Q: 264  CLRNMQGHSGRVSSLSWNGHLLSSGSRSGQIHHHDVRMVQHHVATLSGHSQEVCGLAWSPGGRLLASGSNDNNLLVWANGTTSsaPLHS 352
           *****************************************************************************87655556**** PP
   S: 175  fkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvael 263
            ++h+aavka+aw+Pwq slLasGGGt+D++i++wn +tg +++++d++sqvcs+lws ++kel+s+hG+a+n++tlw yp +  +ael
   Q: 353  LQQHTAAVKALAWCPWQASLLASGGGTNDHHIRLWNINTGICFNAVDAKSQVCSVLWSSEHKELLSAHGYAKNQLTLWAYPAMVPIAEL 441
           ***************************************************************************************** PP
   S: 264  kgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
            gh+ Rvl+++ spdg++++++++De+lr+w++f+ +++
   Q: 442  LGHTERVLQVVASPDGSSVMSVGADESLRLWRCFQGDES 480
           **********************************98876 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MSQFSFESDV SRLLKLDAPI SSGPQPRWQR KAASANTSTV SPMKGTSRTN STSRTPGRTP 60
TSKCQNTPGA KGKSSPGDDR FIPVRNSKNM EVASYLVSRE KHMDLVKPPS LKEKQAAMMH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGCAGT TCTCGTTTGA GAGTGACGTG AGCCGCTTGC TGAAGCTGGA TGCCCCGATT 60
TCCTCGGGTC CCCAGCCGCG TTGGCAGCGC AAGGCGGCGT CCGCGAACAC GAGCACGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0853--WD repeat

Interpro

IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	44.70	2.00e-99	354.00
IUUC-Aml-001545	Ailuropoda melanoleuca	56.20	2.00e-147	514.00
IUUC-Atr-003103	Amborella trichopoda	44.67	3.00e-95	340.00
IUUC-Apl-003255	Anas platyrhynchos	52.49	8.00e-129	452.00
IUUC-Aca-004920	Anolis carolinensis	52.89	3.00e-139	487.00
IUUC-Aly-006253	Arabidopsis lyrata	45.52	6.00e-97	346.00
IUUC-Ath-006795	Arabidopsis thaliana	43.85	6.00e-98	349.00
IUUC-Bgr-012059	Blumeria graminis	41.38	6.00e-83	300.00
IUUC-Bta-012625	Bos taurus	56.40	2.00e-147	514.00
IUUC-Bci-013607	Botrytis cinerea	42.74	3.00e-82	298.00
IUUC-Bdi-014344	Brachypodium distachyon	43.96	9.00e-99	352.00
IUUC-Bol-015368	Brassica oleracea	45.67	5.00e-99	354.00
IUUC-Bra-016738	Brassica rapa	45.07	3.00e-97	347.00
IUUC-Cja-019132	Callithrix jacchus	55.79	7.00e-147	512.00
IUUC-Cfa-020780	Canis familiaris	56.40	7.00e-148	515.00
IUUC-Cpo-022223	Cavia porcellus	56.40	3.00e-135	473.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	47.96	6.00e-102	362.00
IUUC-Csa-023666	Chlorocebus sabaeus	56.20	1.00e-147	514.00
IUUC-Cho-024920	Choloepus hoffmanni	50.00	8.00e-73	266.00
IUUC-Cin-025675	Ciona intestinalis	48.31	6.00e-117	412.00
IUUC-Csv-026019	Ciona savignyi	48.84	2.00e-112	397.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	42.17	6.00e-81	293.00
IUUC-Cne-026872	Cryptococcus neoformans	45.34	3.00e-80	290.00
IUUC-Cme-027234	Cyanidioschyzon merolae	47.95	8.00e-96	342.00
IUUC-Dre-028026	Danio rerio	48.43	5.00e-136	476.00
IUUC-Dno-028865	Dasypus novemcinctus	54.64	5.00e-145	506.00
IUUC-Dor-030958	Dipodomys ordii	55.98	5.00e-145	506.00
IUUC-Dse-031391	Dothistroma septosporum	43.68	3.00e-83	301.00
IUUC-Dme-031905	Drosophila melanogaster	47.86	2.00e-127	447.00
IUUC-Ete-032387	Echinops telfairi	51.45	2.00e-137	480.00
IUUC-Eca-033522	Equus caballus	49.38	5.00e-128	449.00
IUUC-Eeu-035059	Erinaceus europaeus	52.38	2.00e-127	447.00
IUUC-Fca-036346	Felis catus	54.87	1.00e-131	461.00
IUUC-Fal-037558	Ficedula albicollis	49.90	2.00e-137	481.00
IUUC-Fox-037850	Fusarium oxysporum	42.45	4.00e-81	293.00
IUUC-Fso-038375	Fusarium solani	42.74	4.00e-81	294.00
IUUC-Gmo-039284	Gadus morhua	51.02	1.00e-131	461.00
IUUC-Ggr-039864	Gaeumannomyces graminis	42.74	7.00e-83	300.00
IUUC-Gga-040790	Gallus gallus	50.51	4.00e-140	489.00
IUUC-Gac-041431	Gasterosteus aculeatus	51.32	1.00e-128	451.00
IUUC-Gma-043489	Glycine max	45.45	2.00e-99	354.00
IUUC-Ggo-045052	Gorilla gorilla	56.20	3.00e-147	513.00
IUUC-Hsa-046305	Homo sapiens	56.20	3.00e-147	513.00
IUUC-Hvu-047476	Hordeum vulgare	44.47	4.00e-99	353.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	56.61	2.00e-136	478.00
IUUC-Lch-050174	Latimeria chalumnae	46.73	2.00e-119	421.00
IUUC-Lpe-050954	Leersia perrieri	44.42	6.00e-94	336.00
IUUC-Loc-052638	Lepisosteus oculatus	51.93	7.00e-133	465.00
IUUC-Lma-052998	Leptosphaeria maculans	40.21	3.00e-82	298.00
IUUC-Laf-053742	Loxodonta africana	55.79	4.00e-145	506.00
IUUC-Mcc-054948	Macaca mulatta	56.20	1.00e-147	514.00
IUUC-Mor-057277	Magnaporthe oryzae	42.74	2.00e-79	288.00
IUUC-Mpo-057624	Magnaporthe poae	42.74	2.00e-80	291.00
IUUC-Mtr-057725	Medicago truncatula	46.55	6.00e-94	336.00
IUUC-Mga-060102	Meleagris gallopavo	50.10	2.00e-139	487.00
IUUC-Mmr-061615	Microcebus murinus	55.47	5.00e-148	516.00
IUUC-Mdo-061982	Monodelphis domestica	53.38	3.00e-122	432.00
IUUC-Mmu-063864	Mus musculus	55.78	4.00e-144	503.00
IUUC-Mac-064861	Musa acuminata	44.47	7.00e-97	346.00
IUUC-Mpu-066502	Mustela putorius furo	55.51	4.00e-150	522.00
IUUC-Mlu-067277	Myotis lucifugus	52.24	1.00e-136	478.00
IUUC-Ncr-068951	Neurospora crassa	42.29	4.00e-80	290.00
IUUC-Nle-070149	Nomascus leucogenys	55.99	1.00e-145	507.00
IUUC-Opr-070778	Ochotona princeps	54.77	2.00e-97	348.00
IUUC-Ont-071660	Oreochromis niloticus	49.70	6.00e-123	432.00
IUUC-Oan-073677	Ornithorhynchus anatinus	50.41	4.00e-121	426.00
IUUC-Ocu-073797	Oryctolagus cuniculus	56.22	3.00e-146	510.00
IUUC-Oba-075514	Oryza barthii	44.24	4.00e-94	336.00
IUUC-Obr-076018	Oryza brachyantha	44.39	2.00e-100	357.00
IUUC-Ogl-077254	Oryza glaberrima	44.01	1.00e-93	335.00
IUUC-Ogu-078521	Oryza glumaepatula	44.27	2.00e-99	355.00
IUUC-Oin-080094	Oryza indica	44.01	1.00e-93	335.00
IUUC-Olo-080798	Oryza longistaminata	44.50	2.00e-99	355.00
IUUC-Ome-081186	Oryza meridionalis	43.56	1.00e-99	356.00
IUUC-Oni-082243	Oryza nivara	44.01	1.00e-93	335.00
IUUC-Opu-084007	Oryza punctata	43.62	6.00e-92	329.00
IUUC-Oru-084562	Oryza rufipogon	44.27	4.00e-99	354.00
IUUC-Osa-086094	Oryza sativa	43.78	4.00e-93	333.00
IUUC-Ola-086907	Oryzias latipes	49.28	5.00e-119	419.00
IUUC-Olu-087647	Ostreococcus lucimarinus	45.71	1.00e-103	368.00
IUUC-Oga-088184	Otolemur garnettii	55.26	9.00e-144	501.00
IUUC-Oar-090023	Ovis aries	52.69	9.00e-132	461.00
IUUC-Ptr-090935	Pan troglodytes	55.68	5.00e-136	476.00
IUUC-Pan-091845	Papio anubis	56.20	1.00e-147	514.00
IUUC-Psi-093188	Pelodiscus sinensis	53.11	2.00e-149	520.00
IUUC-Pno-094809	Phaeosphaeria nodorum	43.71	1.00e-82	299.00
IUUC-Ppa-095457	Physcomitrella patens	44.30	6.00e-99	352.00
IUUC-Pfo-097429	Poecilia formosa	45.90	1.00e-109	388.00
IUUC-Pab-098603	Pongo abelii	56.20	2.00e-147	513.00
IUUC-Pop-098890	Populus trichocarpa	45.07	8.00e-96	342.00
IUUC-Pca-101062	Procavia capensis	55.49	2.00e-144	504.00
IUUC-Ppe-101865	Prunus persica	43.98	8.00e-88	315.00
IUUC-Pva-102925	Pteropus vampyrus	55.40	6.00e-152	529.00
IUUC-Pte-104142	Pyrenophora teres	41.99	3.00e-82	298.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	41.99	3.00e-82	297.00
IUUC-Rno-106005	Rattus norvegicus	55.38	2.00e-143	500.00
IUUC-Sha-107472	Sarcophilus harrisii	52.54	2.00e-139	487.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	40.67	1.00e-82	298.00
IUUC-Spo-108075	Schizosaccharomyces pombe	42.38	3.00e-85	307.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	42.45	1.00e-81	295.00
IUUC-Smo-108922	Selaginella moellendorffii	44.09	8.00e-106	375.00
IUUC-Sit-110032	Setaria italica	45.06	6.00e-101	359.00
IUUC-Sly-111025	Solanum lycopersicum	46.00	9.00e-92	328.00
IUUC-Stu-112676	Solanum tuberosum	45.52	2.00e-92	331.00
IUUC-Sar-113092	Sorex araneus	53.96	3.00e-135	473.00
IUUC-Sbi-114207	Sorghum bicolor	44.44	3.00e-102	363.00
IUUC-Ssc-115710	Sus scrofa	56.40	3.00e-147	513.00
IUUC-Tgu-117100	Taeniopygia guttata	50.10	4.00e-138	483.00
IUUC-Tru-118184	Takifugu rubripes	47.66	8.00e-101	358.00
IUUC-Tsy-118931	Tarsius syrichta	43.37	1.00e-66	245.00
IUUC-Tni-120474	Tetraodon nigroviridis	49.80	3.00e-119	420.00
IUUC-Tca-120949	Theobroma cacao	44.42	2.00e-97	347.00
IUUC-Tre-122211	Trichoderma reesei	43.59	2.00e-82	298.00
IUUC-Tvi-122531	Trichoderma virens	43.63	7.00e-83	300.00
IUUC-Tae-125122	Triticum aestivum	43.45	1.00e-94	338.00
IUUC-Tur-126018	Triticum urartu	46.21	2.00e-94	338.00
IUUC-Tbe-127384	Tupaia belangeri	58.86	6.00e-101	359.00
IUUC-Ttr-128511	Tursiops truncatus	55.79	1.00e-145	508.00
IUUC-Vda-129993	Verticillium dahliae	41.90	3.00e-81	294.00
IUUC-Vpa-130775	Vicugna pacos	44.95	7.00e-70	256.00
IUUC-Vvi-131245	Vitis vinifera	44.89	7.00e-91	325.00
IUUC-Xtr-131993	Xenopus tropicalis	52.32	5.00e-142	496.00
IUUC-Xma-133332	Xiphophorus maculatus	49.80	4.00e-122	430.00
IUUC-Yli-134501	Yarrowia lipolytica	45.04	1.00e-85	309.00
IUUC-Zma-135135	Zea mays	43.74	3.00e-98	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence