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Tag Content
iUUCD ID IUUC-Oan-073519
Ensembl Protein ID ENSOANP00000007327.2
UniProt Accession F7FVX0; F7FVX0_ORNAN
Genbank Protein ID ENSOANP00000007327
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AAPN01203112
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOANG00000004622.2 ENSOANT00000007329.2 ENSOANP00000007327.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 2.50e-18 65.3 1036 1062
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM

   S: 3    sqvDpeVfsqLPeeiQeEvmaelrqqk 29
    sqvDpeVf++LP+e+QeE++a+++q++
   Q: 1036 SQVDPEVFAALPPELQEELKAAYDQRQ 1062
    8************************98 PP
   

Organism Ornithorhynchus anatinus
Functional Description
(View)

Functional Description



     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MPRFCSGRSA TMRRGGWRKR AENDGWENWG GYMAAKVQKL EEQFRSDAAL QKDGTSTAIF 60
SGVSIYVNGY TDPSADELRK LMMLHGGQYH VYYSRSKTTH IIATNLPNAK IKELKGEKVV 120
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Protein Fasta Sequence



>IUUC-Oan-073519|UBD,UBM|Ornithorhynchus anatinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGTTTTGGT GAAAAAACAG ATAGCGGGTC ATTGGGGACA AAAGATGCGG GAGTGGGCGG 60
GAGGACGAGG TTTGGGAGGG AGAGTTGCTC AGAAGCAGTT GGCAGAGACG GTGGTCATTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Oan-073519|UBD,UBM|Ornithorhynchus anatinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 31.03 8.00e-32 131.00
IUUC-Aml-001185 Ailuropoda melanoleuca 78.42 0.00e+00 1898.00
IUUC-Atr-002915 Amborella trichopoda 32.70 1.00e-84 307.00
IUUC-Apl-004054 Anas platyrhynchos 75.86 0.00e+00 1823.00
IUUC-Aca-004304 Anolis carolinensis 68.40 0.00e+00 1681.00
IUUC-Aly-005696 Arabidopsis lyrata 41.19 1.00e-74 274.00
IUUC-Ath-006893 Arabidopsis thaliana 41.09 5.00e-75 275.00
IUUC-Ago-007722 Ashbya gossypii 29.40 2.00e-38 153.00
IUUC-Acl-008347 Aspergillus clavatus 37.60 4.00e-84 306.00
IUUC-Afl-008444 Aspergillus flavus 36.20 3.00e-84 306.00
IUUC-Afu-008837 Aspergillus fumigatus 28.58 3.00e-102 366.00
IUUC-Ani-009188 Aspergillus nidulans 38.51 8.00e-88 318.00
IUUC-Ang-009866 Aspergillus niger 32.58 1.00e-90 327.00
IUUC-Aor-010107 Aspergillus oryzae 36.20 4.00e-84 305.00
IUUC-Ate-010359 Aspergillus terreus 32.32 2.00e-87 316.00
IUUC-Ame-010664 Astyanax mexicanus 49.63 0.00e+00 1128.00
IUUC-Bgr-012244 Blumeria graminis 29.93 2.00e-75 276.00
IUUC-Bta-013405 Bos taurus 73.87 0.00e+00 1638.00
IUUC-Bci-013849 Botrytis cinerea 35.36 8.00e-83 301.00
IUUC-Bdi-014066 Brachypodium distachyon 36.06 9.00e-82 298.00
IUUC-Bol-015544 Brassica oleracea 42.30 3.00e-77 282.00
IUUC-Bra-017792 Brassica rapa 34.57 9.00e-80 291.00
IUUC-Cel-018148 Caenorhabditis elegans 34.55 2.00e-74 273.00
IUUC-Cja-019742 Callithrix jacchus 68.24 0.00e+00 1345.00
IUUC-Cfa-020112 Canis familiaris 79.53 0.00e+00 1938.00
IUUC-Cpo-022152 Cavia porcellus 75.97 0.00e+00 1892.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 30.17 1.00e-44 174.00
IUUC-Csa-023504 Chlorocebus sabaeus 78.88 0.00e+00 1920.00
IUUC-Cho-024780 Choloepus hoffmanni 62.92 0.00e+00 689.00
IUUC-Cin-025276 Ciona intestinalis 40.50 2.00e-108 386.00
IUUC-Csv-026283 Ciona savignyi 43.71 1.00e-115 409.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 30.30 1.00e-82 301.00
IUUC-Cne-027079 Cryptococcus neoformans 31.59 3.00e-70 259.00
IUUC-Cme-027346 Cyanidioschyzon merolae 31.08 5.00e-38 152.00
IUUC-Dre-028073 Danio rerio 50.30 0.00e+00 1105.00
IUUC-Dno-030038 Dasypus novemcinctus 77.66 0.00e+00 1902.00
IUUC-Dor-031100 Dipodomys ordii 74.77 0.00e+00 1349.00
IUUC-Dse-031310 Dothistroma septosporum 27.26 2.00e-81 297.00
IUUC-Dme-031991 Drosophila melanogaster 42.00 7.00e-112 397.00
IUUC-Ete-033082 Echinops telfairi 71.69 0.00e+00 1296.00
IUUC-Eca-033471 Equus caballus 79.37 0.00e+00 1930.00
IUUC-Eeu-034993 Erinaceus europaeus 76.32 0.00e+00 1277.00
IUUC-Fca-035367 Felis catus 79.20 0.00e+00 1850.00
IUUC-Fal-036973 Ficedula albicollis 74.80 0.00e+00 1743.00
IUUC-Fox-037677 Fusarium oxysporum 34.82 2.00e-81 297.00
IUUC-Fso-038252 Fusarium solani 28.91 1.00e-100 360.00
IUUC-Gmo-039669 Gadus morhua 49.47 8.00e-172 597.00
IUUC-Ggr-039988 Gaeumannomyces graminis 43.02 7.00e-76 278.00
IUUC-Gga-040423 Gallus gallus 75.47 0.00e+00 1801.00
IUUC-Gac-042134 Gasterosteus aculeatus 49.35 0.00e+00 1020.00
IUUC-Gma-042929 Glycine max 34.82 8.00e-85 308.00
IUUC-Ggo-044528 Gorilla gorilla 78.81 0.00e+00 1905.00
IUUC-Hsa-046259 Homo sapiens 78.89 0.00e+00 1885.00
IUUC-Hvu-047139 Hordeum vulgare 46.39 7.00e-48 184.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 77.87 0.00e+00 1894.00
IUUC-Kpa-049169 Komagataella pastoris 30.38 8.00e-61 228.00
IUUC-Lch-050471 Latimeria chalumnae 64.93 0.00e+00 1526.00
IUUC-Lpe-050800 Leersia perrieri 30.52 6.00e-78 285.00
IUUC-Loc-052320 Lepisosteus oculatus 46.05 0.00e+00 914.00
IUUC-Lma-053149 Leptosphaeria maculans 33.44 2.00e-82 300.00
IUUC-Laf-053810 Loxodonta africana 76.79 0.00e+00 1801.00
IUUC-Mcc-055574 Macaca mulatta 78.78 0.00e+00 1880.00
IUUC-Meu-055945 Macropus eugenii 63.26 0.00e+00 1118.00
IUUC-Mor-057195 Magnaporthe oryzae 33.99 1.00e-81 298.00
IUUC-Mpo-057488 Magnaporthe poae 42.40 8.00e-77 281.00
IUUC-Mtr-057955 Medicago truncatula 35.54 1.00e-88 320.00
IUUC-Mla-059027 Melampsora laricipopulina 34.67 8.00e-69 254.00
IUUC-Mga-060156 Meleagris gallopavo 75.08 0.00e+00 1806.00
IUUC-Mvi-060398 Microbotryum violaceum 36.31 3.00e-81 296.00
IUUC-Mmr-061113 Microcebus murinus 79.60 0.00e+00 1901.00
IUUC-Mdo-063001 Monodelphis domestica 80.95 0.00e+00 1972.00
IUUC-Mmu-063180 Mus musculus 75.37 0.00e+00 1810.00
IUUC-Mac-065551 Musa acuminata 38.11 2.00e-53 203.00
IUUC-Mpu-066525 Mustela putorius furo 79.29 0.00e+00 1909.00
IUUC-Mlu-067877 Myotis lucifugus 79.05 0.00e+00 1876.00
IUUC-Nfi-068418 Neosartorya fischeri 34.68 3.00e-83 303.00
IUUC-Ncr-068648 Neurospora crassa 34.94 5.00e-78 286.00
IUUC-Nle-069959 Nomascus leucogenys 78.88 0.00e+00 1898.00
IUUC-Opr-070522 Ochotona princeps 75.51 0.00e+00 1091.00
IUUC-Ont-072293 Oreochromis niloticus 50.67 0.00e+00 861.00
IUUC-Ocu-074492 Oryctolagus cuniculus 75.82 0.00e+00 1753.00
IUUC-Oba-075567 Oryza barthii 37.23 6.00e-79 288.00
IUUC-Obr-076332 Oryza brachyantha 43.57 1.00e-77 284.00
IUUC-Ogl-077348 Oryza glaberrima 37.23 6.00e-79 288.00
IUUC-Ogu-078779 Oryza glumaepatula 37.01 2.00e-78 286.00
IUUC-Oin-079738 Oryza indica 33.40 2.00e-66 247.00
IUUC-Olo-080701 Oryza longistaminata 33.40 9.00e-67 248.00
IUUC-Ome-081708 Oryza meridionalis 36.80 1.00e-77 284.00
IUUC-Oni-082251 Oryza nivara 37.01 2.00e-76 280.00
IUUC-Opu-083528 Oryza punctata 35.50 5.00e-73 269.00
IUUC-Oru-084293 Oryza rufipogon 36.15 1.00e-73 271.00
IUUC-Osa-085549 Oryza sativa 37.23 1.00e-78 287.00
IUUC-Ola-086793 Oryzias latipes 49.95 0.00e+00 867.00
IUUC-Olu-087786 Ostreococcus lucimarinus 30.77 1.00e-51 197.00
IUUC-Oga-089006 Otolemur garnettii 78.83 0.00e+00 1888.00
IUUC-Oar-089597 Ovis aries 75.65 0.00e+00 1817.00
IUUC-Ptr-091520 Pan troglodytes 78.81 0.00e+00 1881.00
IUUC-Pan-092333 Papio anubis 79.11 0.00e+00 1873.00
IUUC-Psi-094004 Pelodiscus sinensis 77.22 0.00e+00 1880.00
IUUC-Pma-094128 Petromyzon marinus 51.90 1.00e-91 330.00
IUUC-Pno-094849 Phaeosphaeria nodorum 30.28 1.00e-73 271.00
IUUC-Ppa-095714 Physcomitrella patens 32.79 3.00e-80 292.00
IUUC-Pfo-096569 Poecilia formosa 53.80 0.00e+00 853.00
IUUC-Pab-097960 Pongo abelii 79.05 0.00e+00 1884.00
IUUC-Pop-098921 Populus trichocarpa 30.68 1.00e-100 361.00
IUUC-Pca-100509 Procavia capensis 63.05 0.00e+00 1081.00
IUUC-Ppe-101730 Prunus persica 42.99 4.00e-81 295.00
IUUC-Pva-102142 Pteropus vampyrus 77.08 0.00e+00 1849.00
IUUC-Pgr-103446 Puccinia graminis 31.36 5.00e-72 265.00
IUUC-Ptt-103849 Puccinia triticina 31.04 7.00e-75 275.00
IUUC-Pte-104128 Pyrenophora teres 32.39 2.00e-76 280.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 36.65 2.00e-73 270.00
IUUC-Rno-104871 Rattus norvegicus 73.05 0.00e+00 1774.00
IUUC-Sce-106236 Saccharomyces cerevisiae 32.55 5.00e-39 155.00
IUUC-Sha-106962 Sarcophilus harrisii 79.61 0.00e+00 1931.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 37.34 8.00e-55 208.00
IUUC-Spo-108170 Schizosaccharomyces pombe 35.12 3.00e-65 242.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 28.38 3.00e-91 329.00
IUUC-Smo-109554 Selaginella moellendorffii 35.64 4.00e-80 292.00
IUUC-Sit-110479 Setaria italica 42.05 5.00e-71 262.00
IUUC-Sly-111752 Solanum lycopersicum 43.90 6.00e-79 288.00
IUUC-Sar-113304 Sorex araneus 78.63 0.00e+00 1838.00
IUUC-Sbi-114196 Sorghum bicolor 35.73 1.00e-72 267.00
IUUC-Sre-115151 Sporisorium reilianum 31.33 4.00e-87 316.00
IUUC-Ssc-116104 Sus scrofa 77.94 0.00e+00 1886.00
IUUC-Tgu-117438 Taeniopygia guttata 75.39 0.00e+00 1790.00
IUUC-Tru-118553 Takifugu rubripes 49.35 0.00e+00 1017.00
IUUC-Tsy-119056 Tarsius syrichta 74.90 0.00e+00 1735.00
IUUC-Tni-119933 Tetraodon nigroviridis 48.38 0.00e+00 991.00
IUUC-Tca-121376 Theobroma cacao 32.53 6.00e-108 385.00
IUUC-Tre-121972 Trichoderma reesei 32.24 3.00e-73 270.00
IUUC-Tvi-122342 Trichoderma virens 33.28 9.00e-71 261.00
IUUC-Tae-123898 Triticum aestivum 37.04 2.00e-78 286.00
IUUC-Tur-126735 Triticum urartu 37.57 5.00e-36 145.00
IUUC-Tme-126999 Tuber melanosporum 33.00 2.00e-79 290.00
IUUC-Tbe-127280 Tupaia belangeri 74.92 3.00e-115 409.00
IUUC-Ttr-129104 Tursiops truncatus 77.41 0.00e+00 1838.00
IUUC-Uma-129562 Ustilago maydis 28.36 2.00e-100 360.00
IUUC-Vda-129862 Verticillium dahliae 33.64 3.00e-80 293.00
IUUC-Vpa-130819 Vicugna pacos 77.19 0.00e+00 1023.00
IUUC-Vvi-131111 Vitis vinifera 35.32 3.00e-85 310.00
IUUC-Xtr-132629 Xenopus tropicalis 60.22 0.00e+00 1376.00
IUUC-Xma-134065 Xiphophorus maculatus 53.08 0.00e+00 836.00
IUUC-Yli-134633 Yarrowia lipolytica 31.81 3.00e-57 216.00
IUUC-Zma-135176 Zea mays 36.17 5.00e-78 285.00
Created Date 25-Jun-2017

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