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Tag Content
UUCD2 ID IUUC-Aml-001230
UUCD1 version UUC-AiM-00491
Ensembl Protein ID ENSAMEP00000007796.1
UniProt Accession G1LLH4; G1LLH4_AILME
Genbank Protein ID ENSAMEP00000007796
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01132541
Gene Name PRPF19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000007375.1 ENSAMET00000008123.1 ENSAMEP00000007796.1
ENSAMEG00000007375.1 ENSAMET00000008126.1 ENSAMEP00000007799.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.60e-15 57.0 3 64
E3 adaptor/Cullin RING/DCX/DWD 1.90e-29 100.5 392 425
UBD/Beta-Prp 1.30e-51 175.7 234 463
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           ++C+Is+e++++P+v+p s+++y+r+ Iek++a++g+ +P+++qpl+ee+l++ ++ + +  +
   Q: 3    LICSISNEVPEHPCVSPvSNHVYERRLIEKYIAENGT-DPINNQPLSEEQLIDIKVAHPIRPK 64
           79**********************************9.***************9998877665 PP
   

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l++++dD ++k+WDlr+
   Q: 392  GHSGPITSIAFseNGYYLATAADDSSVKLWDLRK 425
           8**********976699**************986 PP
   

   UBD/Beta-Prp
   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
            d++ ++tg++d+ + v+d ++++ l++l+gh+++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+ v+ ls++++gd+
   Q: 234  ADTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDY 322
           57899************************************************************************************ PP
   S: 109  lvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
           l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l+
   Q: 323  LLSSSDDQYWAFSDIQTGRVLTKvTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYLA 410
           *********************997777777789************************************9.****************** PP
   S: 197  sgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           ++++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 411  TAADDSSVKLWDLRKLKNFKTLQLDNNfEVKSLIFDQSGTYLALGGTDVQIYI 463
           **************999999999866527*******************99987 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MSLICSISNE VPEHPCVSPV SNHVYERRLI EKYIAENGTD PINNQPLSEE QLIDIKVAHP 60
IRPKPPSATS IPAILKALQD EWDAVMLHSF TLRQQLQTTR QELSHALYQH DAACRVIARL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001230|E3,U-box;E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCCCTGA TCTGCTCGAG TGAGTGTCGC CTGCGGCCGA TCGCAGGTCG CAGGGGGCCG 60
GAGCGCGGAG CGGGAGGAGC TGCGGGCCGC TGCGGCGCCG GGGTCGGGGC GGAGGCGAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001230|E3,U-box;E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00504--Ubox
SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0001833--P:inner cell mass cell proliferation
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000488 Aegilops tauschii 38.78 6.00e-91 329.00
IUUC-Atr-002594 Amborella trichopoda 42.59 5.00e-113 401.00
IUUC-Apl-003686 Anas platyrhynchos 84.42 0.00e+00 692.00
IUUC-Aca-005272 Anolis carolinensis 94.19 0.00e+00 945.00
IUUC-Aly-005586 Arabidopsis lyrata 43.16 3.00e-113 402.00
IUUC-Ath-007696 Arabidopsis thaliana 43.64 2.00e-109 389.00
IUUC-Acl-008335 Aspergillus clavatus 34.91 5.00e-67 248.00
IUUC-Afl-008527 Aspergillus flavus 37.50 9.00e-73 267.00
IUUC-Afu-008957 Aspergillus fumigatus 38.20 5.00e-79 288.00
IUUC-Ani-009280 Aspergillus nidulans 37.30 6.00e-66 244.00
IUUC-Ang-009746 Aspergillus niger 36.34 7.00e-66 244.00
IUUC-Aor-009905 Aspergillus oryzae 37.30 2.00e-76 279.00
IUUC-Ate-010412 Aspergillus terreus 36.88 1.00e-64 240.00
IUUC-Ame-011561 Astyanax mexicanus 80.58 2.00e-101 362.00
IUUC-Bgr-012283 Blumeria graminis 32.52 2.00e-55 209.00
IUUC-Bta-013242 Bos taurus 96.39 0.00e+00 960.00
IUUC-Bci-013901 Botrytis cinerea 33.33 8.00e-63 234.00
IUUC-Bdi-014277 Brachypodium distachyon 43.75 3.00e-117 415.00
IUUC-Bol-016207 Brassica oleracea 44.81 3.00e-112 399.00
IUUC-Bra-017902 Brassica rapa 42.58 1.00e-110 393.00
IUUC-Cel-018271 Caenorhabditis elegans 50.10 1.00e-142 499.00
IUUC-Cja-019879 Callithrix jacchus 95.80 0.00e+00 951.00
IUUC-Cfa-020175 Canis familiaris 96.79 0.00e+00 962.00
IUUC-Cpo-022379 Cavia porcellus 95.99 0.00e+00 957.00
IUUC-Cre-022993 Chlamydomonas reinhardtii 40.36 2.00e-95 343.00
IUUC-Csa-023500 Chlorocebus sabaeus 96.19 0.00e+00 959.00
IUUC-Cho-025065 Choloepus hoffmanni 82.11 9.00e-136 476.00
IUUC-Cin-025699 Ciona intestinalis 67.27 1.00e-169 588.00
IUUC-Csv-026128 Ciona savignyi 64.08 0.00e+00 644.00
IUUC-Cgl-026507 Colletotrichum gloeosporioides 33.72 3.00e-64 239.00
IUUC-Cne-026860 Cryptococcus neoformans 37.96 2.00e-90 326.00
IUUC-Dre-028187 Danio rerio 82.60 0.00e+00 818.00
IUUC-Dno-029453 Dasypus novemcinctus 95.99 0.00e+00 957.00
IUUC-Dor-030150 Dipodomys ordii 92.08 6.00e-116 410.00
IUUC-Dse-031220 Dothistroma septosporum 30.86 2.00e-57 216.00
IUUC-Dme-031906 Drosophila melanogaster 65.40 0.00e+00 637.00
IUUC-Ete-033035 Echinops telfairi 98.19 1.00e-131 462.00
IUUC-Eca-033478 Equus caballus 96.19 0.00e+00 958.00
IUUC-Eeu-034974 Erinaceus europaeus 94.75 0.00e+00 627.00
IUUC-Fca-036194 Felis catus 95.98 0.00e+00 952.00
IUUC-Fal-037417 Ficedula albicollis 94.19 0.00e+00 944.00
IUUC-Fox-037922 Fusarium oxysporum 33.20 4.00e-61 228.00
IUUC-Fso-038256 Fusarium solani 34.74 2.00e-63 236.00
IUUC-Gmo-038713 Gadus morhua 83.40 0.00e+00 831.00
IUUC-Ggr-039854 Gaeumannomyces graminis 32.62 2.00e-52 200.00
IUUC-Gga-041143 Gallus gallus 94.19 0.00e+00 946.00
IUUC-Gac-042129 Gasterosteus aculeatus 82.83 0.00e+00 850.00
IUUC-Gma-044273 Glycine max 45.05 1.00e-115 410.00
IUUC-Ggo-045262 Gorilla gorilla 96.19 0.00e+00 959.00
IUUC-Hsa-046036 Homo sapiens 96.19 0.00e+00 959.00
IUUC-Hvu-047442 Hordeum vulgare 41.43 2.00e-62 232.00
IUUC-Itr-048169 Ictidomys tridecemlineatus 95.59 0.00e+00 916.00
IUUC-Lch-050105 Latimeria chalumnae 87.58 0.00e+00 892.00
IUUC-Lpe-050976 Leersia perrieri 43.95 2.00e-113 402.00
IUUC-Loc-052042 Lepisosteus oculatus 74.19 0.00e+00 654.00
IUUC-Lma-053143 Leptosphaeria maculans 34.02 5.00e-62 233.00
IUUC-Laf-053451 Loxodonta africana 93.02 0.00e+00 948.00
IUUC-Mcc-055786 Macaca mulatta 96.19 0.00e+00 959.00
IUUC-Meu-056161 Macropus eugenii 91.77 6.00e-128 450.00
IUUC-Mor-057215 Magnaporthe oryzae 33.13 3.00e-53 202.00
IUUC-Mpo-057419 Magnaporthe poae 31.65 3.00e-49 189.00
IUUC-Mtr-057756 Medicago truncatula 43.36 3.00e-111 395.00
IUUC-Mla-059085 Melampsora laricipopulina 37.86 2.00e-82 300.00
IUUC-Mga-060158 Meleagris gallopavo 87.04 0.00e+00 830.00
IUUC-Mvi-060441 Microbotryum violaceum 37.55 8.00e-76 277.00
IUUC-Mmr-061085 Microcebus murinus 96.19 0.00e+00 959.00
IUUC-Mdo-061804 Monodelphis domestica 95.79 0.00e+00 955.00
IUUC-Mmu-063608 Mus musculus 92.47 0.00e+00 943.00
IUUC-Mac-064972 Musa acuminata 43.88 4.00e-111 394.00
IUUC-Mpu-065700 Mustela putorius furo 96.79 0.00e+00 963.00
IUUC-Mlu-068223 Myotis lucifugus 92.23 0.00e+00 939.00
IUUC-Nfi-068504 Neosartorya fischeri 36.88 1.00e-78 286.00
IUUC-Ncr-068729 Neurospora crassa 36.31 5.00e-61 228.00
IUUC-Nle-069754 Nomascus leucogenys 96.19 0.00e+00 959.00
IUUC-Opr-070621 Ochotona princeps 91.87 0.00e+00 892.00
IUUC-Ont-071377 Oreochromis niloticus 82.80 0.00e+00 825.00
IUUC-Oan-073498 Ornithorhynchus anatinus 67.89 6.00e-110 390.00
IUUC-Ocu-074182 Oryctolagus cuniculus 92.31 0.00e+00 945.00
IUUC-Oba-075509 Oryza barthii 43.22 3.00e-115 408.00
IUUC-Obr-076480 Oryza brachyantha 44.14 7.00e-117 414.00
IUUC-Ogl-077052 Oryza glaberrima 43.22 3.00e-115 408.00
IUUC-Ogu-078919 Oryza glumaepatula 43.22 3.00e-115 408.00
IUUC-Oin-079357 Oryza indica 42.50 2.00e-108 386.00
IUUC-Olo-080376 Oryza longistaminata 42.80 2.00e-103 369.00
IUUC-Ome-081973 Oryza meridionalis 42.44 4.00e-103 368.00
IUUC-Oni-082849 Oryza nivara 43.41 6.00e-116 411.00
IUUC-Opu-083243 Oryza punctata 43.02 1.00e-114 406.00
IUUC-Oru-084613 Oryza rufipogon 43.55 1.00e-115 409.00
IUUC-Osa-085407 Oryza sativa 43.22 3.00e-115 408.00
IUUC-Ola-086566 Oryzias latipes 81.98 0.00e+00 816.00
IUUC-Olu-087757 Ostreococcus lucimarinus 40.56 2.00e-92 333.00
IUUC-Oga-089010 Otolemur garnettii 95.57 0.00e+00 952.00
IUUC-Oar-089638 Ovis aries 96.39 0.00e+00 960.00
IUUC-Ptr-091141 Pan troglodytes 96.19 0.00e+00 959.00
IUUC-Pan-092662 Papio anubis 96.19 0.00e+00 959.00
IUUC-Psi-093777 Pelodiscus sinensis 93.48 0.00e+00 769.00
IUUC-Pno-095115 Phaeosphaeria nodorum 34.02 1.00e-62 233.00
IUUC-Ppa-095841 Physcomitrella patens 43.88 5.00e-114 404.00
IUUC-Pfo-096390 Poecilia formosa 82.00 0.00e+00 824.00
IUUC-Pab-098250 Pongo abelii 94.46 0.00e+00 904.00
IUUC-Pop-099854 Populus trichocarpa 44.25 8.00e-115 407.00
IUUC-Pca-100553 Procavia capensis 95.59 0.00e+00 949.00
IUUC-Ppe-101383 Prunus persica 42.83 3.00e-107 382.00
IUUC-Pva-102189 Pteropus vampyrus 96.19 0.00e+00 959.00
IUUC-Pgr-103304 Puccinia graminis 36.71 8.00e-82 297.00
IUUC-Ptt-103984 Puccinia triticina 37.60 5.00e-87 315.00
IUUC-Pte-104385 Pyrenophora teres 32.77 3.00e-66 245.00
IUUC-Pyt-104697 Pyrenophora triticirepentis 33.19 2.00e-67 249.00
IUUC-Rno-105581 Rattus norvegicus 95.99 0.00e+00 957.00
IUUC-Sha-107071 Sarcophilus harrisii 91.75 0.00e+00 942.00
IUUC-Sja-107697 Schizosaccharomyces japonicus 31.01 2.00e-35 143.00
IUUC-Spo-108315 Schizosaccharomyces pombe 32.48 2.00e-45 176.00
IUUC-Ssl-108628 Sclerotinia sclerotiorum 34.85 9.00e-61 227.00
IUUC-Smo-109648 Selaginella moellendorffii 43.77 3.00e-115 408.00
IUUC-Sit-109873 Setaria italica 43.27 3.00e-113 402.00
IUUC-Sly-111673 Solanum lycopersicum 45.60 2.00e-109 389.00
IUUC-Stu-112125 Solanum tuberosum 45.21 3.00e-108 385.00
IUUC-Sbi-114696 Sorghum bicolor 42.83 6.00e-106 377.00
IUUC-Sre-115134 Sporisorium reilianum 32.25 4.00e-69 255.00
IUUC-Ssc-116260 Sus scrofa 96.19 0.00e+00 959.00
IUUC-Tgu-116533 Taeniopygia guttata 94.19 0.00e+00 945.00
IUUC-Tru-117800 Takifugu rubripes 81.80 0.00e+00 847.00
IUUC-Tsy-118980 Tarsius syrichta 90.85 0.00e+00 879.00
IUUC-Tni-120334 Tetraodon nigroviridis 61.80 6.00e-174 603.00
IUUC-Tca-121807 Theobroma cacao 43.16 3.00e-113 402.00
IUUC-Tre-121920 Trichoderma reesei 33.47 1.00e-61 230.00
IUUC-Tvi-122294 Trichoderma virens 32.91 2.00e-53 203.00
IUUC-Tae-125713 Triticum aestivum 43.75 6.00e-117 414.00
IUUC-Tur-126664 Triticum urartu 39.86 7.00e-110 391.00
IUUC-Tme-127026 Tuber melanosporum 34.08 7.00e-67 248.00
IUUC-Tbe-127582 Tupaia belangeri 94.44 4.00e-180 624.00
IUUC-Ttr-128313 Tursiops truncatus 95.99 0.00e+00 950.00
IUUC-Uma-129626 Ustilago maydis 33.77 2.00e-71 263.00
IUUC-Vda-129699 Verticillium dahliae 35.52 3.00e-66 245.00
IUUC-Vpa-130593 Vicugna pacos 95.39 0.00e+00 860.00
IUUC-Vvi-131668 Vitis vinifera 43.66 7.00e-114 404.00
IUUC-Xtr-132186 Xenopus tropicalis 82.77 0.00e+00 735.00
IUUC-Xma-133212 Xiphophorus maculatus 81.80 0.00e+00 819.00
IUUC-Yli-134607 Yarrowia lipolytica 57.58 2.00e-41 160.00
IUUC-Zma-135662 Zea mays 44.53 8.00e-116 410.00
Created Date 25-Jun-2017

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