iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062674

UUCD1 version

UUC-MoD-00843

Ensembl Protein ID

ENSMODP00000001681.3

UniProt Accession

F7F5P3; F7F5P3_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001392.3	ENSMODT00000001716.3	ENSMODP00000001681.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-39	132.6	188	225
UBD/Beta-Prp	1.10e-61	208.8	55	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H+  v+c++f +d + ++++s Dg+i+++D +tg +++
   Q: 188  HSRFVNCVRFsPDgNKFATASADGQIYIYDGKTGEKVC 225
           8888*******999****************99998765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           ++h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  +tg+ v  ++
   Q: 55   TEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDTGSSVGEVT 143
           4566667778*************************998777742334567***********9999999988777888888********* PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tg 177
           gh++ + s+++ +++ ++l+++s+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l  ++
   Q: 144  GHNKVINSVDIKQTRpYRLATASDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNKFATASADGQIYIYDGKTGEKVCALggSK 231
           *************999*****************9999998.99********************************************88 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnv.ksvrfspnderlvsgssDgsiri 248
           +h++ +y +s+++++ +l+s+s d+t k+wd+ ++++v+t+n   +   +++  + ++++l+s+s  g i+ 
   Q: 232  AHDGGIYAISWSPDSSHLLSASGDKTAKVWDVGANSVVNTFNMGPNVLdQQLGCLWQKDHLISVSLSGYINY 303
           8****************************************9654433033444456777777777776665 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPYEIKRVFA SLPQVERGVS KIIGGDPKGN NFLYTNGKCV IIRNIDNPAI ADIYTEHAHQ 60
VVVAKYAPSG FYIASGDVSG KLRIWDTTQK EHLLKYEYQP FAGKIKDIAW TEDSKRIAVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAGGGGGA GGGGCCGCGC GGGGGAAGGG CCCCAGGTCC GCGCAGGCTC GAAGCTGTGC 60
AGTTGACTAT ATATGGTCAA AGCTCGGTGA GGACTGCTCG CTGGGCTCTC GCTTCCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0042643--C:actomyosin, actin portion
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0051015--F:actin filament binding
GO:0030042--P:actin filament depolymerization
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0040011--P:locomotion
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

KEGG

mdo:100013344

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	36.45	2.00e-84	306.00
IUUC-Aml-002368	Ailuropoda melanoleuca	91.68	0.00e+00	1137.00
IUUC-Atr-003160	Amborella trichopoda	38.37	3.00e-118	419.00
IUUC-Apl-004012	Anas platyrhynchos	89.11	0.00e+00	1103.00
IUUC-Aca-004707	Anolis carolinensis	84.49	0.00e+00	1075.00
IUUC-Aly-006465	Arabidopsis lyrata	37.56	9.00e-113	400.00
IUUC-Ath-006740	Arabidopsis thaliana	37.40	1.00e-111	397.00
IUUC-Ago-007920	Ashbya gossypii	28.21	2.00e-75	276.00
IUUC-Acl-008262	Aspergillus clavatus	36.44	9.00e-108	384.00
IUUC-Afl-008471	Aspergillus flavus	33.50	3.00e-81	296.00
IUUC-Afu-008989	Aspergillus fumigatus	38.74	3.00e-98	352.00
IUUC-Ani-009167	Aspergillus nidulans	37.70	3.00e-117	415.00
IUUC-Ang-009595	Aspergillus niger	37.97	9.00e-104	370.00
IUUC-Aor-009908	Aspergillus oryzae	37.05	3.00e-105	375.00
IUUC-Ate-010580	Aspergillus terreus	38.02	7.00e-111	395.00
IUUC-Ame-011269	Astyanax mexicanus	60.75	9.00e-136	477.00
IUUC-Bgr-011996	Blumeria graminis	34.96	6.00e-110	391.00
IUUC-Bta-013278	Bos taurus	91.91	0.00e+00	1174.00
IUUC-Bci-013925	Botrytis cinerea	36.10	6.00e-110	391.00
IUUC-Bdi-014659	Brachypodium distachyon	36.12	1.00e-106	380.00
IUUC-Bol-016043	Brassica oleracea	36.11	3.00e-110	392.00
IUUC-Bra-017139	Brassica rapa	37.19	1.00e-112	400.00
IUUC-Cel-018417	Caenorhabditis elegans	40.96	7.00e-123	434.00
IUUC-Cja-019952	Callithrix jacchus	91.91	0.00e+00	1127.00
IUUC-Cfa-020225	Canis familiaris	92.24	0.00e+00	1152.00
IUUC-Cpo-021900	Cavia porcellus	89.68	0.00e+00	1132.00
IUUC-Csa-023028	Chlorocebus sabaeus	92.57	0.00e+00	1133.00
IUUC-Cho-025030	Choloepus hoffmanni	65.83	0.00e+00	734.00
IUUC-Cin-025152	Ciona intestinalis	56.03	1.00e-81	295.00
IUUC-Csv-025986	Ciona savignyi	37.98	9.00e-93	333.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.27	5.00e-112	398.00
IUUC-Cne-026814	Cryptococcus neoformans	34.09	3.00e-98	352.00
IUUC-Dre-027498	Danio rerio	82.05	9.00e-97	345.00
IUUC-Dno-029383	Dasypus novemcinctus	90.76	0.00e+00	1116.00
IUUC-Dor-030633	Dipodomys ordii	89.48	0.00e+00	1045.00
IUUC-Dse-031526	Dothistroma septosporum	38.23	3.00e-115	409.00
IUUC-Dme-031597	Drosophila melanogaster	47.52	2.00e-167	582.00
IUUC-Ete-032780	Echinops telfairi	82.13	0.00e+00	1025.00
IUUC-Eca-034306	Equus caballus	90.85	0.00e+00	1110.00
IUUC-Eeu-034531	Erinaceus europaeus	71.96	2.00e-132	466.00
IUUC-Fca-036301	Felis catus	92.51	0.00e+00	1168.00
IUUC-Fal-037361	Ficedula albicollis	89.42	0.00e+00	1152.00
IUUC-Fox-037924	Fusarium oxysporum	35.99	2.00e-102	366.00
IUUC-Fso-038199	Fusarium solani	35.28	7.00e-99	354.00
IUUC-Gmo-039238	Gadus morhua	72.65	0.00e+00	898.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.98	1.00e-99	357.00
IUUC-Gga-040235	Gallus gallus	89.93	0.00e+00	1127.00
IUUC-Gac-042363	Gasterosteus aculeatus	72.65	0.00e+00	935.00
IUUC-Gma-044189	Glycine max	37.70	3.00e-116	412.00
IUUC-Ggo-044632	Gorilla gorilla	90.28	0.00e+00	1100.00
IUUC-Hsa-045792	Homo sapiens	92.08	0.00e+00	1150.00
IUUC-Hvu-047517	Hordeum vulgare	36.05	5.00e-110	391.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	91.51	0.00e+00	1135.00
IUUC-Kpa-049183	Komagataella pastoris	32.07	5.00e-86	311.00
IUUC-Lch-050428	Latimeria chalumnae	77.10	0.00e+00	1016.00
IUUC-Lpe-051306	Leersia perrieri	36.17	9.00e-111	394.00
IUUC-Loc-052096	Lepisosteus oculatus	71.27	0.00e+00	899.00
IUUC-Lma-053313	Leptosphaeria maculans	38.95	9.00e-117	416.00
IUUC-Laf-054060	Loxodonta africana	89.44	0.00e+00	1111.00
IUUC-Mcc-055619	Macaca mulatta	90.34	0.00e+00	1102.00
IUUC-Meu-056689	Macropus eugenii	81.66	0.00e+00	659.00
IUUC-Mor-056940	Magnaporthe oryzae	35.49	9.00e-99	354.00
IUUC-Mpo-057557	Magnaporthe poae	31.13	3.00e-73	269.00
IUUC-Mtr-058478	Medicago truncatula	36.07	2.00e-111	396.00
IUUC-Mla-059103	Melampsora laricipopulina	33.27	4.00e-79	289.00
IUUC-Mga-060150	Meleagris gallopavo	89.40	0.00e+00	1115.00
IUUC-Mvi-060448	Microbotryum violaceum	32.00	3.00e-75	276.00
IUUC-Mmr-061226	Microcebus murinus	90.26	0.00e+00	1123.00
IUUC-Mmu-064170	Mus musculus	91.25	0.00e+00	1150.00
IUUC-Mac-065124	Musa acuminata	37.93	2.00e-115	409.00
IUUC-Mpu-066001	Mustela putorius furo	88.55	0.00e+00	1133.00
IUUC-Mlu-067253	Myotis lucifugus	91.18	0.00e+00	1139.00
IUUC-Nfi-068550	Neosartorya fischeri	38.57	6.00e-113	401.00
IUUC-Ncr-068948	Neurospora crassa	38.20	1.00e-117	416.00
IUUC-Nle-070115	Nomascus leucogenys	88.35	0.00e+00	1031.00
IUUC-Opr-070254	Ochotona princeps	89.00	0.00e+00	1068.00
IUUC-Ont-071666	Oreochromis niloticus	76.40	0.00e+00	971.00
IUUC-Oan-073594	Ornithorhynchus anatinus	93.09	3.00e-167	580.00
IUUC-Ocu-074824	Oryctolagus cuniculus	89.60	0.00e+00	1095.00
IUUC-Oba-075010	Oryza barthii	37.05	6.00e-113	401.00
IUUC-Obr-076364	Oryza brachyantha	36.99	1.00e-112	400.00
IUUC-Ogl-077019	Oryza glaberrima	37.05	6.00e-113	401.00
IUUC-Ogu-078496	Oryza glumaepatula	37.05	6.00e-113	401.00
IUUC-Oin-080116	Oryza indica	37.21	2.00e-113	403.00
IUUC-Olo-080290	Oryza longistaminata	37.05	1.00e-112	400.00
IUUC-Ome-081969	Oryza meridionalis	37.05	6.00e-113	401.00
IUUC-Oni-082075	Oryza nivara	37.05	5.00e-113	401.00
IUUC-Opu-083959	Oryza punctata	36.89	1.00e-112	400.00
IUUC-Oru-084711	Oryza rufipogon	37.05	6.00e-113	401.00
IUUC-Osa-085958	Oryza sativa	37.21	2.00e-113	403.00
IUUC-Ola-086968	Oryzias latipes	76.90	0.00e+00	987.00
IUUC-Oga-089108	Otolemur garnettii	91.00	0.00e+00	1172.00
IUUC-Oar-089986	Ovis aries	86.07	0.00e+00	1082.00
IUUC-Ptr-091281	Pan troglodytes	92.33	0.00e+00	1140.00
IUUC-Pan-092585	Papio anubis	92.57	0.00e+00	1134.00
IUUC-Psi-093811	Pelodiscus sinensis	88.70	0.00e+00	1145.00
IUUC-Pma-094542	Petromyzon marinus	69.03	0.00e+00	893.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.82	4.00e-109	388.00
IUUC-Ppa-095876	Physcomitrella patens	36.20	2.00e-113	403.00
IUUC-Pfo-096973	Poecilia formosa	75.91	0.00e+00	1003.00
IUUC-Pab-098391	Pongo abelii	92.41	0.00e+00	1134.00
IUUC-Pop-098850	Populus trichocarpa	37.75	5.00e-116	411.00
IUUC-Pca-100257	Procavia capensis	58.94	5.00e-88	318.00
IUUC-Ppe-101578	Prunus persica	38.66	6.00e-117	414.00
IUUC-Pva-102872	Pteropus vampyrus	86.99	0.00e+00	1098.00
IUUC-Pgr-103593	Puccinia graminis	32.55	4.00e-81	295.00
IUUC-Pte-104365	Pyrenophora teres	38.35	3.00e-111	395.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.03	6.00e-114	404.00
IUUC-Rno-105737	Rattus norvegicus	91.75	0.00e+00	1174.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.22	1.00e-69	257.00
IUUC-Sha-107084	Sarcophilus harrisii	91.62	0.00e+00	1016.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	36.39	2.00e-113	403.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.28	1.00e-96	347.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.34	7.00e-109	387.00
IUUC-Smo-109255	Selaginella moellendorffii	36.08	2.00e-105	376.00
IUUC-Sit-109962	Setaria italica	38.03	9.00e-116	410.00
IUUC-Sly-110897	Solanum lycopersicum	38.79	2.00e-118	419.00
IUUC-Stu-111971	Solanum tuberosum	38.13	2.00e-117	416.00
IUUC-Sar-113415	Sorex araneus	70.85	5.00e-108	385.00
IUUC-Sbi-114857	Sorghum bicolor	37.54	7.00e-113	401.00
IUUC-Sre-114900	Sporisorium reilianum	35.45	4.00e-95	342.00
IUUC-Tgu-117256	Taeniopygia guttata	89.37	0.00e+00	1148.00
IUUC-Tru-117871	Takifugu rubripes	70.08	0.00e+00	894.00
IUUC-Tsy-119172	Tarsius syrichta	92.08	9.00e-135	473.00
IUUC-Tni-120339	Tetraodon nigroviridis	69.47	0.00e+00	921.00
IUUC-Tca-121609	Theobroma cacao	37.48	2.00e-115	409.00
IUUC-Tre-122076	Trichoderma reesei	35.63	2.00e-96	346.00
IUUC-Tvi-122528	Trichoderma virens	35.13	6.00e-99	354.00
IUUC-Tae-123530	Triticum aestivum	36.32	1.00e-110	393.00
IUUC-Tur-126845	Triticum urartu	36.05	9.00e-83	300.00
IUUC-Tme-127217	Tuber melanosporum	35.63	2.00e-105	376.00
IUUC-Tbe-127526	Tupaia belangeri	88.61	0.00e+00	1115.00
IUUC-Ttr-128898	Tursiops truncatus	84.51	0.00e+00	1064.00
IUUC-Uma-129631	Ustilago maydis	33.39	2.00e-95	343.00
IUUC-Vda-129732	Verticillium dahliae	34.93	5.00e-92	331.00
IUUC-Vvi-131217	Vitis vinifera	38.70	9.00e-115	407.00
IUUC-Xtr-132860	Xenopus tropicalis	73.42	0.00e+00	948.00
IUUC-Xma-133830	Xiphophorus maculatus	75.91	0.00e+00	1003.00
IUUC-Yli-134335	Yarrowia lipolytica	33.01	1.00e-76	280.00
IUUC-Zma-135907	Zea mays	37.54	2.00e-113	403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence