iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049353

Ensembl Protein ID

CAY67271

UniProt Accession

C4QVJ8; C4QVJ8_KOMPG

Genbank Protein ID

CAY67271.1

Protein Name

Probable cytosolic iron-sulfur protein assembly protein 1

Genbank Nucleotide ID

FN392319

Gene Name

CIA1; PAS_chr1-3_0207

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-3_0207	CAY67271	CAY67271

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-37	122.2	107	139
UBD/Beta-Prp	1.20e-42	144.1	74	345

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH++++ ++++ +d  +l+s+s+D++i +W+ +
   Q: 107  GHENEIKGVSWsHDgVYLASCSRDKSIWIWEAD 139
           8***********888***************965 PP

UBD/Beta-Prp

   S: 25   latgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw....dlstgkcvhtlkghedsvlslsfspsgdklvsGs 113
           la gs d+ti +w +++  l        ++ ++ghe+e++ v++s+dg +l+++s+D+ i +w    + + ++cv ++++h+++v  +++++  ++l+s s
   Q: 74   LAIGSFDSTISIWGNEEAVLedednwtlMAIIEGHENEIKGVSWSHDGVYLASCSRDKSIWIWeaddNNEEFECVFVVQEHSQDVKHVTWHQHENVLASSS 174
           899**************999*******99999*******************************7776666******************************* PP
   S: 114  hdrtirv.....wdletgqclee.tlsghdgvvncvvvhpdg...nllvsGslDrtvrlWdl........................ktgkllrtltgghtd 181
            d+t+++     +  +++ +++   l+gh+g+v++  + ++g     l s+s+D+t+r+W++                         + +l + l   h++
   Q: 175  YDDTVKLfkqddY--DEDDWVNVaDLTGHEGTVWSSDFEKKGervTRLSSSSDDGTIRIWKIlhaaddqpsidsklpstiktdtnqDMWELETILPIIHHG 273
           *******555444..33333332599************999853445789******************************996666555555555667*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlq.tgec.vrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdl 251
           ++ys+++ +ng +++s++ dg++ ++    ++e  + + + h+  v+ ++    +++rl+++++Dg +++W l
   Q: 274  PIYSVAWGENG-YIASVGSDGRIVVYKELnSKEWqIIISQPHSHGVYEINNIkWHGDRLITAGDDGLVKLWEL 345
           **********8.9*************75525555333444488888877655468****************75 PP

Organism

Komagataella pastoris

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MSLSLVHTFT GHTDKCWATS IHSKLPLLAT VSGDRTCRVY NLETKRLIVV LDDDSHSKTL 60
SSVEWKPTGE FPSLAIGSFD STISIWGNEE AVLEDEDNWT LMAIIEGHEN EIKGVSWSHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCTAT CTTTGGTTCA CACATTCACA GGTCACACAG ATAAATGCTG GGCTACTTCC 60
ATTCACTCTA AACTTCCTTT ATTGGCAACA GTCTCCGGGG ACAGAACTTG TCGGGTCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0005634--C:nucleus
GO:0016226--P:iron-sulfur cluster assembly

KEGG

ppa:PAS_chr1-3_0207

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	37.19	3.00e-40	157.00
IUUC-Aml-001317	Ailuropoda melanoleuca	36.44	3.00e-48	183.00
IUUC-Atr-003029	Amborella trichopoda	35.33	5.00e-53	199.00
IUUC-Aly-006458	Arabidopsis lyrata	32.52	1.00e-46	177.00
IUUC-Ath-006671	Arabidopsis thaliana	33.06	2.00e-46	177.00
IUUC-Ago-007820	Ashbya gossypii	48.01	3.00e-85	306.00
IUUC-Acl-008042	Aspergillus clavatus	35.07	5.00e-59	219.00
IUUC-Afl-008639	Aspergillus flavus	37.14	2.00e-65	240.00
IUUC-Afu-008899	Aspergillus fumigatus	36.20	4.00e-61	226.00
IUUC-Ani-009453	Aspergillus nidulans	36.24	6.00e-65	239.00
IUUC-Ang-009758	Aspergillus niger	37.40	1.00e-64	238.00
IUUC-Aor-010212	Aspergillus oryzae	37.14	2.00e-65	240.00
IUUC-Ate-010314	Aspergillus terreus	38.37	3.00e-65	239.00
IUUC-Ame-010676	Astyanax mexicanus	36.62	3.00e-56	209.00
IUUC-Bgr-012095	Blumeria graminis	34.88	1.00e-54	205.00
IUUC-Bta-012884	Bos taurus	35.88	5.00e-48	182.00
IUUC-Bci-013622	Botrytis cinerea	35.28	9.00e-50	188.00
IUUC-Bdi-014614	Brachypodium distachyon	35.44	2.00e-50	191.00
IUUC-Bol-016439	Brassica oleracea	34.25	1.00e-45	174.00
IUUC-Bra-016830	Brassica rapa	34.17	1.00e-44	171.00
IUUC-Cel-018709	Caenorhabditis elegans	30.29	2.00e-37	147.00
IUUC-Cja-019822	Callithrix jacchus	36.83	2.00e-47	180.00
IUUC-Cfa-020823	Canis familiaris	36.44	7.00e-48	182.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	33.88	5.00e-50	189.00
IUUC-Csa-023754	Chlorocebus sabaeus	36.83	9.00e-48	181.00
IUUC-Cin-025395	Ciona intestinalis	35.96	1.00e-57	214.00
IUUC-Csv-025943	Ciona savignyi	35.88	2.00e-57	213.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	31.60	3.00e-47	180.00
IUUC-Cne-026939	Cryptococcus neoformans	28.27	2.00e-38	151.00
IUUC-Cme-027239	Cyanidioschyzon merolae	33.86	3.00e-34	137.00
IUUC-Dre-028172	Danio rerio	36.62	7.00e-53	198.00
IUUC-Dno-029472	Dasypus novemcinctus	38.00	1.00e-43	167.00
IUUC-Dor-031134	Dipodomys ordii	39.61	7.00e-36	142.00
IUUC-Dse-031535	Dothistroma septosporum	32.71	8.00e-55	205.00
IUUC-Dme-032020	Drosophila melanogaster	35.85	1.00e-57	214.00
IUUC-Eca-033700	Equus caballus	36.44	2.00e-48	184.00
IUUC-Eeu-035010	Erinaceus europaeus	35.88	8.00e-46	175.00
IUUC-Fca-036309	Felis catus	32.77	1.00e-41	161.00
IUUC-Fal-037243	Ficedula albicollis	43.17	7.00e-39	151.00
IUUC-Fox-038058	Fusarium oxysporum	32.83	6.00e-51	193.00
IUUC-Fso-038459	Fusarium solani	32.17	2.00e-49	187.00
IUUC-Gmo-039375	Gadus morhua	33.52	9.00e-42	161.00
IUUC-Ggr-040002	Gaeumannomyces graminis	29.69	1.00e-43	168.00
IUUC-Gga-040294	Gallus gallus	36.63	2.00e-40	157.00
IUUC-Gac-042499	Gasterosteus aculeatus	34.17	3.00e-40	156.00
IUUC-Gma-043543	Glycine max	35.87	2.00e-52	197.00
IUUC-Ggo-045181	Gorilla gorilla	36.83	9.00e-48	181.00
IUUC-Hsa-046528	Homo sapiens	36.83	9.00e-48	181.00
IUUC-Hvu-047341	Hordeum vulgare	41.18	3.00e-36	142.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	36.69	1.00e-47	181.00
IUUC-Lch-049763	Latimeria chalumnae	35.41	1.00e-50	191.00
IUUC-Lpe-051500	Leersia perrieri	32.91	1.00e-46	177.00
IUUC-Loc-052021	Lepisosteus oculatus	36.83	1.00e-46	177.00
IUUC-Lma-053331	Leptosphaeria maculans	37.56	8.00e-61	226.00
IUUC-Laf-054558	Loxodonta africana	35.59	1.00e-47	181.00
IUUC-Mcc-055374	Macaca mulatta	36.83	2.00e-47	180.00
IUUC-Meu-056042	Macropus eugenii	40.71	3.00e-37	146.00
IUUC-Mor-057187	Magnaporthe oryzae	32.86	8.00e-50	188.00
IUUC-Mtr-058072	Medicago truncatula	35.25	2.00e-53	200.00
IUUC-Mla-059108	Melampsora laricipopulina	29.82	2.00e-47	181.00
IUUC-Mga-059370	Meleagris gallopavo	33.45	2.00e-30	123.00
IUUC-Mvi-060495	Microbotryum violaceum	33.51	5.00e-47	179.00
IUUC-Mmr-060902	Microcebus murinus	36.52	3.00e-48	183.00
IUUC-Mdo-062510	Monodelphis domestica	34.46	5.00e-45	172.00
IUUC-Mmu-063575	Mus musculus	36.24	2.00e-46	177.00
IUUC-Mac-065322	Musa acuminata	34.43	4.00e-51	192.00
IUUC-Mpu-065925	Mustela putorius furo	36.44	5.00e-48	182.00
IUUC-Mlu-067755	Myotis lucifugus	35.31	3.00e-47	180.00
IUUC-Nfi-068327	Neosartorya fischeri	35.20	8.00e-62	228.00
IUUC-Ncr-068845	Neurospora crassa	30.16	4.00e-44	170.00
IUUC-Nle-069406	Nomascus leucogenys	35.69	1.00e-43	167.00
IUUC-Opr-070416	Ochotona princeps	38.69	8.00e-21	92.40
IUUC-Ont-071936	Oreochromis niloticus	35.11	3.00e-43	166.00
IUUC-Oan-073452	Ornithorhynchus anatinus	43.33	3.00e-30	122.00
IUUC-Ocu-074791	Oryctolagus cuniculus	36.69	1.00e-47	181.00
IUUC-Oba-075636	Oryza barthii	36.91	1.00e-53	201.00
IUUC-Obr-076742	Oryza brachyantha	38.49	9.00e-48	181.00
IUUC-Ogl-077766	Oryza glaberrima	36.91	1.00e-53	201.00
IUUC-Ogu-079039	Oryza glumaepatula	36.64	2.00e-52	197.00
IUUC-Oin-079315	Oryza indica	38.89	3.00e-48	183.00
IUUC-Olo-080669	Oryza longistaminata	33.92	1.00e-48	184.00
IUUC-Ome-081490	Oryza meridionalis	36.91	1.00e-53	201.00
IUUC-Oni-082572	Oryza nivara	36.91	1.00e-53	201.00
IUUC-Opu-083732	Oryza punctata	36.91	3.00e-53	200.00
IUUC-Oru-084763	Oryza rufipogon	36.91	1.00e-53	201.00
IUUC-Osa-085372	Oryza sativa	36.91	1.00e-53	201.00
IUUC-Ola-087379	Oryzias latipes	34.93	3.00e-43	166.00
IUUC-Olu-087801	Ostreococcus lucimarinus	31.43	4.00e-37	145.00
IUUC-Oga-089076	Otolemur garnettii	36.80	3.00e-47	179.00
IUUC-Oar-090022	Ovis aries	36.16	7.00e-48	182.00
IUUC-Ptr-090809	Pan troglodytes	36.83	9.00e-48	181.00
IUUC-Pan-091685	Papio anubis	37.25	4.00e-48	183.00
IUUC-Psi-093046	Pelodiscus sinensis	36.16	2.00e-47	180.00
IUUC-Pma-094181	Petromyzon marinus	36.49	1.00e-56	211.00
IUUC-Pno-094882	Phaeosphaeria nodorum	36.84	1.00e-60	224.00
IUUC-Ppa-095172	Physcomitrella patens	33.69	1.00e-45	174.00
IUUC-Pfo-096396	Poecilia formosa	33.62	2.00e-43	167.00
IUUC-Pab-098427	Pongo abelii	36.65	2.00e-47	180.00
IUUC-Pop-100016	Populus trichocarpa	35.04	1.00e-51	194.00
IUUC-Pca-101048	Procavia capensis	36.44	5.00e-49	185.00
IUUC-Ppe-102050	Prunus persica	35.05	6.00e-51	192.00
IUUC-Pva-103117	Pteropus vampyrus	35.88	3.00e-48	183.00
IUUC-Pgr-103307	Puccinia graminis	29.86	4.00e-44	170.00
IUUC-Ptt-103938	Puccinia triticina	33.23	6.00e-38	149.00
IUUC-Pte-104315	Pyrenophora teres	36.73	2.00e-63	234.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	36.73	2.00e-63	234.00
IUUC-Rno-105523	Rattus norvegicus	35.96	3.00e-46	176.00
IUUC-Sce-106297	Saccharomyces cerevisiae	49.71	3.00e-84	302.00
IUUC-Sha-106981	Sarcophilus harrisii	35.33	1.00e-40	157.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	40.97	8.00e-71	259.00
IUUC-Spo-108214	Schizosaccharomyces pombe	41.72	1.00e-69	255.00
IUUC-Smo-109034	Selaginella moellendorffii	33.15	2.00e-43	167.00
IUUC-Sit-110663	Setaria italica	36.09	1.00e-50	191.00
IUUC-Sly-110898	Solanum lycopersicum	36.07	3.00e-48	183.00
IUUC-Stu-112647	Solanum tuberosum	39.67	2.00e-41	160.00
IUUC-Sbi-114288	Sorghum bicolor	36.91	9.00e-53	198.00
IUUC-Sre-115065	Sporisorium reilianum	33.72	3.00e-54	203.00
IUUC-Ssc-115960	Sus scrofa	33.90	2.00e-50	190.00
IUUC-Tru-118382	Takifugu rubripes	34.83	4.00e-53	199.00
IUUC-Tsy-119585	Tarsius syrichta	34.38	1.00e-41	160.00
IUUC-Tni-120133	Tetraodon nigroviridis	33.99	3.00e-48	182.00
IUUC-Tca-121167	Theobroma cacao	35.50	2.00e-46	177.00
IUUC-Tre-122119	Trichoderma reesei	31.16	4.00e-50	189.00
IUUC-Tvi-122407	Trichoderma virens	33.33	7.00e-55	205.00
IUUC-Tae-125748	Triticum aestivum	36.36	1.00e-49	187.00
IUUC-Tur-126682	Triticum urartu	37.32	1.00e-41	160.00
IUUC-Tme-127095	Tuber melanosporum	37.18	4.00e-69	253.00
IUUC-Tbe-128004	Tupaia belangeri	36.24	1.00e-47	181.00
IUUC-Ttr-129284	Tursiops truncatus	35.29	5.00e-46	176.00
IUUC-Uma-129527	Ustilago maydis	34.77	7.00e-56	209.00
IUUC-Vda-129854	Verticillium dahliae	31.26	4.00e-49	186.00
IUUC-Vpa-130681	Vicugna pacos	45.05	2.00e-16	77.00
IUUC-Vvi-131004	Vitis vinifera	36.19	2.00e-48	184.00
IUUC-Xtr-131928	Xenopus tropicalis	34.18	3.00e-45	173.00
IUUC-Xma-134290	Xiphophorus maculatus	33.80	2.00e-43	167.00
IUUC-Yli-134364	Yarrowia lipolytica	50.73	7.00e-91	324.00
IUUC-Zma-135658	Zea mays	36.64	7.00e-52	195.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence