iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afl-008494

Ensembl Protein ID

EED57944

UniProt Accession

B8N002; B8N002_ASPFN

Genbank Protein ID

EED57944.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 39 kDa subunit homolog

Genbank Nucleotide ID

EQ963472

Gene Name

TIF34; AFLA_086420

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AFLA_086420	EED57944	EED57944

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-18	64.1	50	88

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++ ++ ++  ++  ll++Gs D+t+++W+++tg ++k
   Q: 50   GHQGAIWTVDVsPNtVLLATGSADNTVRLWNVKTGECIK 88
           8**********9776999******************986 PP

Organism

Aspergillus flavus

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILLSGHE RSLNQIKFNR DGDLLFSVAK DKIVCAWWSA NGERLGTYNG HQGAIWTVDV 60
SPNTVLLATG SADNTVRLWN VKTGECIKVW DFPTAVKRVE FTPDGSRLLA VTEKRMGFLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCTA TTTTGCTTTC GGGCCATGTG CGTTCGCCTT ACAACCGTCC GATGATTCTC 60
TTTTTTCACC GGCAATGAAA AATATAACGA ACCAGCCACT GACAGAGACT TTGCGCTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0022627--C:cytosolic small ribosomal subunit
GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0071540--C:eukaryotic translation initiation factor 3 complex, eIF3e
GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0043614--C:multi-eIF complex
GO:0034399--C:nuclear periphery
GO:0003743--F:translation initiation factor activity
GO:0071470--P:cellular response to osmotic stress
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation
GO:0002188--P:translation reinitiation

KEGG

afv:AFLA_086420

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	52.34	3.00e-31	127.00
IUUC-Aml-001321	Ailuropoda melanoleuca	52.76	7.00e-101	358.00
IUUC-Atr-002468	Amborella trichopoda	44.62	9.00e-48	181.00
IUUC-Apl-003841	Anas platyrhynchos	53.07	6.00e-103	365.00
IUUC-Aca-005123	Anolis carolinensis	53.52	8.00e-103	364.00
IUUC-Aly-005473	Arabidopsis lyrata	43.77	4.00e-78	282.00
IUUC-Ath-007094	Arabidopsis thaliana	43.50	2.00e-77	280.00
IUUC-Ago-008000	Ashbya gossypii	53.57	6.00e-106	375.00
IUUC-Acl-008098	Aspergillus clavatus	92.06	0.00e+00	654.00
IUUC-Afu-009080	Aspergillus fumigatus	93.82	0.00e+00	662.00
IUUC-Ani-009230	Aspergillus nidulans	91.37	0.00e+00	649.00
IUUC-Aor-010114	Aspergillus oryzae	100.00	0.00e+00	699.00
IUUC-Ate-010285	Aspergillus terreus	91.37	0.00e+00	650.00
IUUC-Ame-011534	Astyanax mexicanus	51.22	2.00e-101	359.00
IUUC-Bgr-012121	Blumeria graminis	70.36	4.00e-141	491.00
IUUC-Bta-013143	Bos taurus	53.21	5.00e-102	362.00
IUUC-Bci-013950	Botrytis cinerea	74.92	2.00e-155	539.00
IUUC-Bdi-015019	Brachypodium distachyon	46.57	2.00e-83	300.00
IUUC-Bol-015709	Brassica oleracea	44.38	9.00e-78	282.00
IUUC-Bra-017760	Brassica rapa	44.07	1.00e-77	282.00
IUUC-Cel-018226	Caenorhabditis elegans	41.03	3.00e-76	276.00
IUUC-Cja-019741	Callithrix jacchus	52.91	2.00e-101	360.00
IUUC-Cfa-021204	Canis familiaris	52.76	1.00e-100	357.00
IUUC-Cpo-021661	Cavia porcellus	52.76	3.00e-101	359.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	44.75	3.00e-79	286.00
IUUC-Csa-024038	Chlorocebus sabaeus	52.91	2.00e-101	360.00
IUUC-Cin-025597	Ciona intestinalis	48.49	3.00e-96	342.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	71.08	2.00e-147	513.00
IUUC-Cne-026838	Cryptococcus neoformans	56.40	1.00e-110	390.00
IUUC-Cme-027304	Cyanidioschyzon merolae	41.82	6.00e-71	258.00
IUUC-Dre-028567	Danio rerio	51.36	1.00e-99	354.00
IUUC-Dno-029171	Dasypus novemcinctus	52.76	2.00e-100	357.00
IUUC-Dor-030257	Dipodomys ordii	40.68	7.00e-36	142.00
IUUC-Dse-031191	Dothistroma septosporum	71.73	2.00e-145	506.00
IUUC-Dme-031879	Drosophila melanogaster	46.79	2.00e-90	323.00
IUUC-Ete-032336	Echinops telfairi	47.83	2.00e-54	203.00
IUUC-Eca-033259	Equus caballus	52.76	2.00e-100	357.00
IUUC-Eeu-035153	Erinaceus europaeus	46.00	7.00e-31	125.00
IUUC-Fca-036489	Felis catus	52.76	2.00e-100	357.00
IUUC-Fal-037485	Ficedula albicollis	53.07	4.00e-103	365.00
IUUC-Fox-037860	Fusarium oxysporum	73.43	5.00e-152	528.00
IUUC-Fso-038188	Fusarium solani	73.13	1.00e-147	513.00
IUUC-Gmo-039311	Gadus morhua	51.23	1.00e-99	353.00
IUUC-Ggr-040045	Gaeumannomyces graminis	74.63	3.00e-157	545.00
IUUC-Gga-040645	Gallus gallus	51.94	2.00e-101	360.00
IUUC-Gac-042086	Gasterosteus aculeatus	51.07	2.00e-98	349.00
IUUC-Gma-043246	Glycine max	45.54	7.00e-81	291.00
IUUC-Ggo-045578	Gorilla gorilla	52.91	2.00e-101	360.00
IUUC-Hsa-046734	Homo sapiens	52.91	2.00e-101	360.00
IUUC-Hvu-047553	Hordeum vulgare	46.46	1.00e-83	301.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	52.45	3.00e-100	356.00
IUUC-Kpa-049325	Komagataella pastoris	57.83	8.00e-117	411.00
IUUC-Lch-049620	Latimeria chalumnae	50.67	4.00e-88	315.00
IUUC-Lpe-051338	Leersia perrieri	45.54	3.00e-77	279.00
IUUC-Loc-052094	Lepisosteus oculatus	47.24	2.00e-86	310.00
IUUC-Lma-053047	Leptosphaeria maculans	71.77	2.00e-147	512.00
IUUC-Laf-053801	Loxodonta africana	52.34	3.00e-98	349.00
IUUC-Mcc-055498	Macaca mulatta	47.09	9.00e-83	298.00
IUUC-Meu-056729	Macropus eugenii	48.48	4.00e-90	322.00
IUUC-Mor-057025	Magnaporthe oryzae	74.33	4.00e-155	538.00
IUUC-Mpo-057511	Magnaporthe poae	73.73	7.00e-154	534.00
IUUC-Mtr-058051	Medicago truncatula	45.85	1.00e-80	291.00
IUUC-Mla-059061	Melampsora laricipopulina	54.60	2.00e-110	390.00
IUUC-Mga-059229	Meleagris gallopavo	52.74	2.00e-101	360.00
IUUC-Mvi-060399	Microbotryum violaceum	55.12	2.00e-106	377.00
IUUC-Mmr-060764	Microcebus murinus	52.91	6.00e-102	362.00
IUUC-Mdo-062088	Monodelphis domestica	51.99	8.00e-99	351.00
IUUC-Mmu-064304	Mus musculus	52.60	1.00e-101	360.00
IUUC-Mac-065520	Musa acuminata	45.91	4.00e-81	292.00
IUUC-Mpu-066340	Mustela putorius furo	52.76	2.00e-100	357.00
IUUC-Mlu-067111	Myotis lucifugus	52.76	3.00e-101	359.00
IUUC-Nfi-068478	Neosartorya fischeri	93.82	0.00e+00	662.00
IUUC-Ncr-068820	Neurospora crassa	72.84	2.00e-152	529.00
IUUC-Nle-069903	Nomascus leucogenys	52.76	7.00e-101	358.00
IUUC-Opr-070221	Ochotona princeps	51.99	6.00e-100	355.00
IUUC-Ont-071765	Oreochromis niloticus	50.76	1.00e-99	354.00
IUUC-Oan-073660	Ornithorhynchus anatinus	49.50	1.00e-84	304.00
IUUC-Ocu-074039	Oryctolagus cuniculus	52.76	1.00e-100	357.00
IUUC-Oba-075395	Oryza barthii	40.06	3.00e-66	243.00
IUUC-Obr-076334	Oryza brachyantha	44.65	1.00e-77	281.00
IUUC-Ogl-077751	Oryza glaberrima	45.87	3.00e-83	299.00
IUUC-Ogu-078207	Oryza glumaepatula	45.87	6.00e-84	301.00
IUUC-Oin-079878	Oryza indica	45.57	5.00e-83	298.00
IUUC-Olo-080677	Oryza longistaminata	39.90	1.00e-74	271.00
IUUC-Ome-081228	Oryza meridionalis	35.68	2.00e-35	140.00
IUUC-Oni-082411	Oryza nivara	38.84	9.00e-65	238.00
IUUC-Opu-083136	Oryza punctata	45.57	8.00e-83	298.00
IUUC-Oru-084916	Oryza rufipogon	44.05	4.00e-81	292.00
IUUC-Osa-085776	Oryza sativa	45.87	3.00e-83	299.00
IUUC-Ola-087053	Oryzias latipes	53.21	3.00e-103	365.00
IUUC-Olu-087602	Ostreococcus lucimarinus	46.91	2.00e-88	317.00
IUUC-Oga-088154	Otolemur garnettii	52.76	7.00e-101	358.00
IUUC-Oar-089915	Ovis aries	53.07	3.00e-101	359.00
IUUC-Ptr-091124	Pan troglodytes	44.44	6.00e-75	271.00
IUUC-Pan-092035	Papio anubis	52.91	2.00e-101	360.00
IUUC-Psi-094096	Pelodiscus sinensis	51.39	4.00e-64	235.00
IUUC-Pno-094988	Phaeosphaeria nodorum	66.07	2.00e-129	453.00
IUUC-Ppa-095536	Physcomitrella patens	47.37	9.00e-84	301.00
IUUC-Pfo-096101	Poecilia formosa	51.38	3.00e-100	356.00
IUUC-Pab-097726	Pongo abelii	52.91	2.00e-101	360.00
IUUC-Pop-099617	Populus trichocarpa	45.85	3.00e-81	293.00
IUUC-Pca-101014	Procavia capensis	52.91	9.00e-102	361.00
IUUC-Ppe-101320	Prunus persica	45.85	6.00e-81	291.00
IUUC-Pva-102789	Pteropus vampyrus	46.79	2.00e-84	303.00
IUUC-Pgr-103479	Puccinia graminis	54.60	2.00e-109	386.00
IUUC-Ptt-103981	Puccinia triticina	54.30	3.00e-108	382.00
IUUC-Pte-104278	Pyrenophora teres	71.99	1.00e-144	503.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	71.99	1.00e-144	503.00
IUUC-Rno-105867	Rattus norvegicus	47.02	2.00e-80	290.00
IUUC-Sce-106251	Saccharomyces cerevisiae	54.60	3.00e-108	382.00
IUUC-Sha-107039	Sarcophilus harrisii	51.67	4.00e-99	352.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	63.41	2.00e-130	456.00
IUUC-Spo-108314	Schizosaccharomyces pombe	62.50	2.00e-128	450.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	74.92	2.00e-155	539.00
IUUC-Smo-108728	Selaginella moellendorffii	44.27	4.00e-80	289.00
IUUC-Sit-110801	Setaria italica	47.38	5.00e-86	308.00
IUUC-Sly-111326	Solanum lycopersicum	45.23	2.00e-80	290.00
IUUC-Stu-112458	Solanum tuberosum	45.54	4.00e-80	289.00
IUUC-Sbi-114063	Sorghum bicolor	46.75	4.00e-85	305.00
IUUC-Sre-115096	Sporisorium reilianum	57.83	2.00e-107	380.00
IUUC-Ssc-116080	Sus scrofa	52.91	1.00e-101	360.00
IUUC-Tgu-116988	Taeniopygia guttata	53.07	4.00e-103	365.00
IUUC-Tru-118766	Takifugu rubripes	51.07	1.00e-99	354.00
IUUC-Tni-120197	Tetraodon nigroviridis	51.07	5.00e-100	355.00
IUUC-Tca-121316	Theobroma cacao	45.85	4.00e-81	292.00
IUUC-Tre-122097	Trichoderma reesei	73.43	3.00e-152	528.00
IUUC-Tvi-122442	Trichoderma virens	73.73	6.00e-152	528.00
IUUC-Tae-125800	Triticum aestivum	45.97	1.00e-83	301.00
IUUC-Tur-126334	Triticum urartu	39.81	6.00e-64	235.00
IUUC-Tme-127038	Tuber melanosporum	73.11	2.00e-149	519.00
IUUC-Ttr-128659	Tursiops truncatus	49.54	1.00e-82	297.00
IUUC-Uma-129464	Ustilago maydis	58.43	8.00e-108	381.00
IUUC-Vda-129841	Verticillium dahliae	72.75	5.00e-151	525.00
IUUC-Vvi-131076	Vitis vinifera	45.99	3.00e-82	296.00
IUUC-Xtr-132395	Xenopus tropicalis	52.60	2.00e-102	363.00
IUUC-Xma-133383	Xiphophorus maculatus	51.38	4.00e-100	355.00
IUUC-Yli-134586	Yarrowia lipolytica	59.34	4.00e-112	395.00
IUUC-Zma-135904	Zea mays	47.99	2.00e-86	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence