iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000105.4	ENSCAFT00000000166.4	ENSCAFP00000000146.3
ENSCAFG00000000105.4	ENSCAFT00000047112.1	ENSCAFP00000043022.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	92.37	0.00e+00	1424.00	IUUC-Hsa-046966

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

SCLDLEQCSL KVLEPEGSPS LCLLKLMGEK GCTVTELSDF LQAMEHTEVL LLLSPPGIKI 60
TVNPESKAVL AGQFVKLCCR ATGHPFVQYQ WFKMNKEIPN GNASELIFNT VHVKDAGFYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTGTCTGG ACTTGGAGCA GTGTTCTCTT AAGGTCTTGG AGCCTGAAGG AAGTCCAAGC 60
TTATGTTTAC TGAAGCTGAT GGGTGAGAAA GGTTGTACGG TCACAGAACT GAGTGACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029030--Caspase-like_dom
IPR011029--DEATH-like_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR033540--MALT1
IPR001309--Pept_C14_p20

PROSITE

PS50208--CASPASE_P20
PS50835--IG_LIKE

Pfam

PF13895--Ig_2

SMART

SM00409--IG
SM00408--IGc2

Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0019209--F:kinase activator activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0001923--P:B-1 B cell differentiation
GO:0045087--P:innate immune response
GO:0051168--P:nuclear export
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032743--P:positive regulation of interleukin-2 production
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0050870--P:positive regulation of T cell activation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0051259--P:protein oligomerization
GO:0042981--P:regulation of apoptotic process
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0009620--P:response to fungus
GO:0002237--P:response to molecule of bacterial origin
GO:0042098--P:T cell proliferation
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003814	Anas platyrhynchos	69.45	0.00e+00	1063.00
IUUC-Aca-005192	Anolis carolinensis	61.22	0.00e+00	731.00
IUUC-Aly-005742	Arabidopsis lyrata	35.06	2.40e-02	33.10
IUUC-Ame-010608	Astyanax mexicanus	54.59	0.00e+00	767.00
IUUC-Bta-012436	Bos taurus	92.13	0.00e+00	1422.00
IUUC-Cel-018688	Caenorhabditis elegans	26.18	8.00e-43	168.00
IUUC-Cja-018945	Callithrix jacchus	79.66	0.00e+00	1177.00
IUUC-Cpo-022400	Cavia porcellus	89.18	0.00e+00	1387.00
IUUC-Csa-023556	Chlorocebus sabaeus	91.55	0.00e+00	1342.00
IUUC-Cho-024489	Choloepus hoffmanni	87.59	2.00e-144	506.00
IUUC-Csv-026274	Ciona savignyi	31.58	3.00e-11	62.00
IUUC-Dre-028666	Danio rerio	54.39	0.00e+00	744.00
IUUC-Dno-029397	Dasypus novemcinctus	90.25	0.00e+00	1389.00
IUUC-Dse-031279	Dothistroma septosporum	22.78	7.60e-02	31.60
IUUC-Ete-032600	Echinops telfairi	66.76	3.00e-125	442.00
IUUC-Eca-033475	Equus caballus	95.13	0.00e+00	1477.00
IUUC-Eeu-034788	Erinaceus europaeus	88.16	0.00e+00	1358.00
IUUC-Fca-035687	Felis catus	92.50	0.00e+00	1412.00
IUUC-Fal-037432	Ficedula albicollis	66.31	0.00e+00	1006.00
IUUC-Gmo-038533	Gadus morhua	52.81	0.00e+00	668.00
IUUC-Gga-040429	Gallus gallus	69.88	0.00e+00	1058.00
IUUC-Gac-041963	Gasterosteus aculeatus	59.22	0.00e+00	811.00
IUUC-Ggo-045328	Gorilla gorilla	91.84	0.00e+00	1390.00
IUUC-Hsa-046966	Homo sapiens	92.24	0.00e+00	1396.00
IUUC-Itr-048424	Ictidomys tridecemlineatus	92.39	0.00e+00	909.00
IUUC-Lch-049486	Latimeria chalumnae	67.39	0.00e+00	988.00
IUUC-Loc-051782	Lepisosteus oculatus	61.08	0.00e+00	868.00
IUUC-Laf-053612	Loxodonta africana	89.88	0.00e+00	1391.00
IUUC-Mcc-054811	Macaca mulatta	89.34	0.00e+00	1348.00
IUUC-Meu-056602	Macropus eugenii	90.19	2.00e-129	456.00
IUUC-Mmr-060713	Microcebus murinus	93.32	0.00e+00	1459.00
IUUC-Mdo-062385	Monodelphis domestica	78.90	0.00e+00	1206.00
IUUC-Mpu-065996	Mustela putorius furo	96.51	0.00e+00	1412.00
IUUC-Mlu-067627	Myotis lucifugus	91.26	0.00e+00	1356.00
IUUC-Nle-069583	Nomascus leucogenys	92.24	0.00e+00	1399.00
IUUC-Opr-070641	Ochotona princeps	86.70	0.00e+00	1036.00
IUUC-Ont-071363	Oreochromis niloticus	59.40	0.00e+00	791.00
IUUC-Oan-073407	Ornithorhynchus anatinus	80.08	0.00e+00	736.00
IUUC-Ola-086554	Oryzias latipes	58.66	0.00e+00	761.00
IUUC-Oga-088538	Otolemur garnettii	84.08	0.00e+00	1239.00
IUUC-Oar-090012	Ovis aries	91.62	0.00e+00	1391.00
IUUC-Ptr-090677	Pan troglodytes	92.24	0.00e+00	1398.00
IUUC-Pan-092262	Papio anubis	91.84	0.00e+00	1392.00
IUUC-Psi-093186	Pelodiscus sinensis	69.15	0.00e+00	1004.00
IUUC-Pfo-097154	Poecilia formosa	59.20	0.00e+00	769.00
IUUC-Pab-098695	Pongo abelii	85.39	0.00e+00	1268.00
IUUC-Pca-100956	Procavia capensis	94.71	0.00e+00	750.00
IUUC-Pva-102917	Pteropus vampyrus	84.30	0.00e+00	865.00
IUUC-Pte-104125	Pyrenophora teres	22.34	8.30e-01	27.70
IUUC-Rno-105680	Rattus norvegicus	88.81	0.00e+00	1314.00
IUUC-Sha-107559	Sarcophilus harrisii	81.39	0.00e+00	1236.00
IUUC-Sar-113054	Sorex araneus	85.26	0.00e+00	778.00
IUUC-Ssc-116110	Sus scrofa	90.85	0.00e+00	1373.00
IUUC-Tgu-116542	Taeniopygia guttata	73.19	0.00e+00	976.00
IUUC-Tru-118019	Takifugu rubripes	58.28	0.00e+00	766.00
IUUC-Tsy-119591	Tarsius syrichta	79.18	0.00e+00	1134.00
IUUC-Tbe-128075	Tupaia belangeri	64.50	2.00e-120	426.00
IUUC-Ttr-128309	Tursiops truncatus	85.64	0.00e+00	1293.00
IUUC-Vpa-130271	Vicugna pacos	93.04	0.00e+00	977.00
IUUC-Xtr-132554	Xenopus tropicalis	61.46	0.00e+00	875.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence