iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-018065

Ensembl Protein ID

Bra029426.1-P

UniProt Accession

M4EKV9; M4EKV9_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra029426	Bra029426.1	Bra029426.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	2.90e-141	471.1	157	457
E3 adaptor/Cullin RING/DCX/DWD	1.30e-23	83.0	290	320

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladleekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltghsa 97
           +kvldap l+ddfylnL+dWs++nvlav+L+++vylw+a+t++v+kl+d+  +++v+svsw  +gt+la+Gt++g+vei+D+ ++k++rt++gh  
   Q: 157  YKVLDAPALQDDFYLNLVDWSAQNVLAVGLANCVYLWNACTSKVTKLCDIGVDESVCSVSWALRGTHLAIGTSSGTVEIWDALRCKRIRTMEGHRL 252
           89********************************************************************************************** PP
   S: 98   rvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfkehkaavkaiawsPwqks 193
           rvgaL+W + vlssGsrd++il+rd+r++e ++s+l++h++evCGlkw+ d+++LasGGnDn++ vw+++s++P+ ++ eh+aavkaiawsP+ ++
   Q: 253  RVGALAWSSSVLSSGSRDKSILQRDIRCQEDHVSKLTGHKSEVCGLKWSYDNRELASGGNDNKLLVWNQHSTQPVLRYCEHTAAVKAIAWSPHLHG 348
           ************************************************************************************************ PP
   S: 194  lLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDe 289
           lLasGGGtaDrci+fwnt+t + l+++dt sqvc+l+wsk+ +elvsthG+++n+i++wkyp++sk+a+l+gh++Rvl+la+spdg++ivt+agDe
   Q: 349  LLASGGGTADRCIRFWNTTTNTSLNCVDTTSQVCNLAWSKNVNELVSTHGYSQNQIIVWKYPTMSKLATLTGHTFRVLYLAVSPDGQTIVTGAGDE 444
           ************************************************************************************************ PP
   S: 290  tlrfwklfdkkka 302
           tlrfw++f + k+
   Q: 445  TLRFWNIFPSPKS 457
           ********87665 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH+++v++l++  +++ l+sG++D+++ vW+
   Q: 290  GHKSEVCGLKWsyDNRELASGGNDNKLLVWN 320
           8**********964499*************9 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MEVDGEDPPK KPSSSSQLNL PPSMNRPTVS LETQRINRLI DSNHYHSPSK PIYSDRFIPS 60
RSGSNFALFG LEPSPGKEDG PGSYAGMLRA AMFEPDTPEK GDVVTGFSPS RKMFRYKTET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGTTG ACGGAGAAGA TCCTCCCAAG AAGCCATCTT CTTCCTCTCA GCTCAACCTC 60
CCACCGTCAA TGAATCGACC GACGGTCTCA CTCGAGACCC AACGAATCAA CCGTTTAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006358	Arabidopsis lyrata	84.34	0.00e+00	790.00
IUUC-Ath-006892	Arabidopsis thaliana	83.75	0.00e+00	762.00
IUUC-Bol-015548	Brassica oleracea	96.65	0.00e+00	919.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence