iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026962

Ensembl Protein ID

AAW46261

UniProt Accession

Q5KA01; Q5KA01_CRYNJ

Genbank Protein ID

AAW46261.2

Protein Name

Ubiquitin-specific protease, putative

Genbank Nucleotide ID

AE017351

Gene Name

CNK00100

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNK00100	AAW46261	AAW46261

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-59	199.2	667	1097

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel....................wkskkkavsprellkalkke 80
           Gl N gN C+ N +LQ+L+ +p+++el+ e + ++l+++    +k++ll+++  +++e+                     +s+k+a+ p+++++a+k e
   Q: 667  GLINTGNMCFANTILQVLVYCPPFTELFEE-FGKRLKAD--LARKTPLLEAMIIFLREFvsspesststtstpkgkgkdKDSRKEAFIPENVYDAMK-E 761
           9*****************************.99999876..78999999999999999977777777776666655543377788***********8.5 PP
   S: 81   aeefs...gyeqqDaqEflaflldqleeelkk......eknkpkeeeeeedkselsde....................................aeekk 134
           +++f+      q+Da+E+l f+l++l+ee+         ++++  + + +d      +                                    +  + 
   Q: 762  NKRFDsmrRGYQEDAEEYLGFFLNTLHEEIIYllsqtsTTSSSMPNGQPSD------SssrqverpvspragagingnadsssgwlevgkkqktHVVRA 854
           66677444667*******************554432222222222233333......1345667************************99988888888 PP
   S: 135  kkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilh 233
           +++ +s +s+lF+g+l+s +  +  ++ s++ ep + l+l++ g       s++d+L++++++e ++g   +y+    ++++a+k++ +++ P+vLi h
   Q: 855  TESRESAVSRLFGGKLRSILHTP-GQKDSVTIEPYQPLQLDITGPAIL---SITDALRAISTPEIIHG---VYSAAKGGEVDATKTVYVETWPKVLICH 946
           99999************776665.678899****************88...****************9...999999********************** PP
   S: 234  LkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.............................. 301
           LkRf ++ e++   k +k v +   L + +  +sp +  +++ kY L++vv+H+G s+s+GHY++ v                                
   Q: 947  LKRFVYDTEEGGVVKRSKAVAYGVDLAIPNEIISPARRTSTSIKYALFGVVYHHGsSASGGHYTVSVARpssssssstsstsiqspagtssslppppss 1045
           ******************************99999999999****************************999999999999999999999999988877 PP
   S: 302  ..ekgkWllfdDskVtevkeeevleetg..............staYvlfYkr 337
                +Wl+fdD++V+ev+ee+v+ + +              + aY+lfYkr
   Q: 1046 ttIASRWLHFDDENVREVREEDVVVSLDqakggetgsvggreRCAYLLFYKR 1097
           766777**************9999866689********************98 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MAAPFPDNGS PVPSVPFPSI HNPLPYTPPP YHAPAAYYRH APPYYPPPPA PYPSYAPIPM 60
GGAGPGPATM QNGYGGYGEY GVYYGYAGYP DYQPPHAGYP PADGDDYSDP AKTPSSAHAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCCC CCTTCCCGGA CAACGGCTCG CCGGTCCCCT CTGTGCCGTT CCCGAGCATC 60
CACAACCCCC TCCCCTACAC GCCCCCCCCC TACCATGCGC CCGCCGCCTA CTACCGCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CNK00100

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	26.52	3.00e-34	138.00
IUUC-Aml-001584	Ailuropoda melanoleuca	31.77	2.00e-52	198.00
IUUC-Atr-002927	Amborella trichopoda	32.21	8.00e-37	146.00
IUUC-Apl-003988	Anas platyrhynchos	31.98	3.00e-46	178.00
IUUC-Aca-004461	Anolis carolinensis	32.68	3.00e-37	147.00
IUUC-Aly-006038	Arabidopsis lyrata	27.99	2.00e-33	135.00
IUUC-Ath-007328	Arabidopsis thaliana	27.60	8.00e-33	133.00
IUUC-Ago-007717	Ashbya gossypii	29.16	6.00e-52	197.00
IUUC-Acl-008188	Aspergillus clavatus	37.33	1.00e-83	302.00
IUUC-Afl-008456	Aspergillus flavus	40.55	2.00e-62	231.00
IUUC-Afu-009067	Aspergillus fumigatus	36.43	2.00e-84	305.00
IUUC-Ani-009483	Aspergillus nidulans	37.80	1.00e-82	299.00
IUUC-Ang-009639	Aspergillus niger	38.22	1.00e-83	302.00
IUUC-Aor-010040	Aspergillus oryzae	36.90	2.00e-80	292.00
IUUC-Ate-010310	Aspergillus terreus	37.56	6.00e-82	296.00
IUUC-Ame-011012	Astyanax mexicanus	32.05	7.00e-38	150.00
IUUC-Bgr-012311	Blumeria graminis	40.77	6.00e-64	236.00
IUUC-Bta-013299	Bos taurus	35.42	8.00e-50	190.00
IUUC-Bci-013783	Botrytis cinerea	38.77	9.00e-77	279.00
IUUC-Bdi-015039	Brachypodium distachyon	26.10	5.00e-36	144.00
IUUC-Bol-015910	Brassica oleracea	29.60	2.00e-41	162.00
IUUC-Bra-017076	Brassica rapa	29.60	6.00e-44	170.00
IUUC-Cja-018715	Callithrix jacchus	32.74	1.00e-53	202.00
IUUC-Cfa-020194	Canis familiaris	32.52	3.00e-52	198.00
IUUC-Cpo-022272	Cavia porcellus	32.74	2.00e-52	198.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	33.08	1.00e-27	116.00
IUUC-Csa-023310	Chlorocebus sabaeus	32.08	1.00e-52	199.00
IUUC-Cho-024966	Choloepus hoffmanni	36.36	3.00e-16	78.60
IUUC-Cin-025616	Ciona intestinalis	30.09	5.00e-45	174.00
IUUC-Csv-026043	Ciona savignyi	31.76	6.00e-45	172.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	37.65	5.00e-69	254.00
IUUC-Cme-027113	Cyanidioschyzon merolae	25.74	2.00e-21	95.10
IUUC-Dre-028072	Danio rerio	33.03	1.00e-50	193.00
IUUC-Dno-029489	Dasypus novemcinctus	32.08	5.00e-51	194.00
IUUC-Dor-031068	Dipodomys ordii	35.26	7.00e-18	84.00
IUUC-Dse-031553	Dothistroma septosporum	38.81	3.00e-70	258.00
IUUC-Dme-031759	Drosophila melanogaster	28.99	5.00e-41	161.00
IUUC-Ete-032549	Echinops telfairi	31.14	2.00e-27	115.00
IUUC-Eca-033380	Equus caballus	32.52	3.00e-52	198.00
IUUC-Eeu-034818	Erinaceus europaeus	35.69	4.00e-50	191.00
IUUC-Fca-035535	Felis catus	34.35	3.00e-45	174.00
IUUC-Fal-036627	Ficedula albicollis	32.96	2.00e-53	202.00
IUUC-Fox-037904	Fusarium oxysporum	43.09	1.00e-81	296.00
IUUC-Fso-038170	Fusarium solani	40.92	4.00e-74	271.00
IUUC-Gmo-039499	Gadus morhua	31.17	2.00e-45	175.00
IUUC-Ggr-040042	Gaeumannomyces graminis	44.48	2.00e-90	325.00
IUUC-Gga-040571	Gallus gallus	32.73	1.00e-47	183.00
IUUC-Gac-041345	Gasterosteus aculeatus	30.79	1.00e-44	173.00
IUUC-Gma-044407	Glycine max	29.89	4.00e-40	157.00
IUUC-Ggo-044652	Gorilla gorilla	32.30	9.00e-53	199.00
IUUC-Hsa-045864	Homo sapiens	32.30	9.00e-53	199.00
IUUC-Hvu-047071	Hordeum vulgare	27.75	1.00e-40	159.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	35.15	1.00e-50	192.00
IUUC-Kpa-049132	Komagataella pastoris	30.27	1.00e-49	189.00
IUUC-Lch-050040	Latimeria chalumnae	32.05	3.00e-48	184.00
IUUC-Loc-052449	Lepisosteus oculatus	31.46	3.00e-46	178.00
IUUC-Lma-053248	Leptosphaeria maculans	41.40	1.00e-75	275.00
IUUC-Laf-054121	Loxodonta africana	35.23	7.00e-50	190.00
IUUC-Mcc-055514	Macaca mulatta	32.08	8.00e-53	199.00
IUUC-Meu-056873	Macropus eugenii	30.24	2.00e-17	82.40
IUUC-Mor-057243	Magnaporthe oryzae	39.86	7.00e-87	313.00
IUUC-Mpo-057439	Magnaporthe poae	45.58	1.00e-87	315.00
IUUC-Mtr-058457	Medicago truncatula	29.66	2.00e-39	154.00
IUUC-Mla-058929	Melampsora laricipopulina	37.82	1.00e-74	272.00
IUUC-Mga-060157	Meleagris gallopavo	32.21	7.00e-46	177.00
IUUC-Mvi-060442	Microbotryum violaceum	40.41	8.00e-82	296.00
IUUC-Mmr-061062	Microcebus murinus	32.31	5.00e-52	197.00
IUUC-Mdo-062798	Monodelphis domestica	31.49	2.00e-46	178.00
IUUC-Mmu-064050	Mus musculus	32.52	9.00e-54	203.00
IUUC-Mac-065202	Musa acuminata	30.11	8.00e-38	149.00
IUUC-Mpu-066554	Mustela putorius furo	32.74	7.00e-52	196.00
IUUC-Mlu-068003	Myotis lucifugus	32.30	2.00e-51	195.00
IUUC-Nfi-068612	Neosartorya fischeri	37.33	3.00e-82	298.00
IUUC-Ncr-068878	Neurospora crassa	43.01	1.00e-81	296.00
IUUC-Nle-069661	Nomascus leucogenys	32.08	9.00e-53	199.00
IUUC-Opr-070944	Ochotona princeps	31.97	3.00e-27	114.00
IUUC-Ont-071266	Oreochromis niloticus	31.24	2.00e-47	182.00
IUUC-Oan-073442	Ornithorhynchus anatinus	32.82	2.00e-55	208.00
IUUC-Ocu-073788	Oryctolagus cuniculus	34.46	4.00e-50	191.00
IUUC-Oba-075085	Oryza barthii	29.66	3.00e-30	123.00
IUUC-Obr-076663	Oryza brachyantha	27.65	2.00e-34	138.00
IUUC-Ogl-076937	Oryza glaberrima	28.54	8.00e-43	166.00
IUUC-Ogu-078909	Oryza glumaepatula	28.44	1.00e-40	159.00
IUUC-Oin-079617	Oryza indica	28.54	1.00e-42	166.00
IUUC-Olo-081043	Oryza longistaminata	24.50	7.00e-16	77.00
IUUC-Oni-082914	Oryza nivara	28.44	1.00e-40	159.00
IUUC-Oru-084878	Oryza rufipogon	28.44	8.00e-41	159.00
IUUC-Osa-085822	Oryza sativa	28.60	4.00e-44	170.00
IUUC-Ola-086931	Oryzias latipes	30.22	2.00e-45	175.00
IUUC-Oga-088443	Otolemur garnettii	32.08	1.00e-51	196.00
IUUC-Oar-089325	Ovis aries	35.87	9.00e-50	189.00
IUUC-Ptr-091584	Pan troglodytes	31.18	1.00e-45	176.00
IUUC-Pan-092551	Papio anubis	31.19	6.00e-48	183.00
IUUC-Psi-093366	Pelodiscus sinensis	31.44	9.00e-21	92.80
IUUC-Pno-095136	Phaeosphaeria nodorum	37.63	4.00e-64	238.00
IUUC-Ppa-095574	Physcomitrella patens	29.62	9.00e-40	156.00
IUUC-Pfo-097462	Poecilia formosa	31.69	6.00e-46	177.00
IUUC-Pab-098547	Pongo abelii	32.08	1.00e-52	199.00
IUUC-Pop-099529	Populus trichocarpa	30.27	2.00e-40	158.00
IUUC-Pca-101066	Procavia capensis	32.33	5.00e-39	154.00
IUUC-Ppe-102110	Prunus persica	32.68	5.00e-37	146.00
IUUC-Pva-103015	Pteropus vampyrus	32.23	5.00e-52	197.00
IUUC-Ptt-103998	Puccinia triticina	37.16	8.00e-79	286.00
IUUC-Pte-104417	Pyrenophora teres	42.74	5.00e-79	287.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	43.17	9.00e-80	289.00
IUUC-Rno-105533	Rattus norvegicus	32.74	1.00e-54	206.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.82	2.00e-45	176.00
IUUC-Sha-106590	Sarcophilus harrisii	33.20	2.00e-34	138.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	37.56	5.00e-76	276.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.10	6.00e-75	273.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	38.53	4.00e-76	277.00
IUUC-Smo-109645	Selaginella moellendorffii	30.42	2.00e-21	94.00
IUUC-Sit-110781	Setaria italica	29.98	6.00e-44	170.00
IUUC-Sly-111797	Solanum lycopersicum	29.31	2.00e-38	151.00
IUUC-Stu-112188	Solanum tuberosum	28.54	1.00e-39	155.00
IUUC-Sbi-114862	Sorghum bicolor	32.12	8.00e-36	143.00
IUUC-Sre-115162	Sporisorium reilianum	42.77	9.00e-95	339.00
IUUC-Ssc-115505	Sus scrofa	32.96	1.00e-40	158.00
IUUC-Tgu-116535	Taeniopygia guttata	32.51	7.00e-53	200.00
IUUC-Tru-117542	Takifugu rubripes	31.60	6.00e-49	187.00
IUUC-Tni-120200	Tetraodon nigroviridis	31.54	1.00e-47	182.00
IUUC-Tca-121548	Theobroma cacao	32.30	8.00e-34	136.00
IUUC-Tre-122124	Trichoderma reesei	38.66	1.00e-82	298.00
IUUC-Tvi-122457	Trichoderma virens	36.19	4.00e-75	274.00
IUUC-Tae-125352	Triticum aestivum	28.86	1.00e-42	166.00
IUUC-Tme-127180	Tuber melanosporum	38.54	9.00e-88	316.00
IUUC-Tbe-127530	Tupaia belangeri	32.36	6.00e-28	117.00
IUUC-Ttr-128549	Tursiops truncatus	31.74	1.00e-25	110.00
IUUC-Uma-129381	Ustilago maydis	43.13	4.00e-96	343.00
IUUC-Vda-129889	Verticillium dahliae	35.99	6.00e-65	240.00
IUUC-Vpa-130100	Vicugna pacos	29.27	1.00e-40	159.00
IUUC-Vvi-131366	Vitis vinifera	33.24	8.00e-42	162.00
IUUC-Xtr-132048	Xenopus tropicalis	32.28	4.00e-51	194.00
IUUC-Xma-133593	Xiphophorus maculatus	31.60	1.00e-45	176.00
IUUC-Yli-134338	Yarrowia lipolytica	26.88	1.00e-37	149.00
IUUC-Zma-135255	Zea mays	28.80	5.00e-41	161.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence