iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054243

UUCD1 version

UUC-LoA-01099

Ensembl Protein ID

ENSLAFP00000011964.3

UniProt Accession

G3TCY5; G3TCY5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014285.3	ENSLAFT00000014287.3	ENSLAFP00000011964.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-79	267.8	123	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS++QcL+ +p+l+++ll+ ++ ++++     +   ++l+ +q+ + +   ++ +a++p ++++ lkk+a++f+  +q
   Q: 123  GLHNLGNTCFLNSTVQCLTYTPPLANYLLSkEHARSCH-----QGGFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLKKIARHFRFGNQ 206
           9*****************************33333333.....456799999999999999**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l+  a+ + +++ ++l++++F+g l+s++kc  c++vs +++p ld+ l++++
   Q: 207  EDAHEFLRYTIDAMQKAC------------------LNGYAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEIRQ 277
           ******************..................444556788999***************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c kckkk+ a+k++++++ + vL+l LkRf    ++    ki+k v +p+ L+++p++++
   Q: 278  AA-----NIVRALEVFVKPDVLSGENAYMCAKCKKKVPASKRFSIHRASSVLTLSLKRF----ANFTGGKITKDVGYPEFLNIRPYMSQ 357
           **.....9***************************************************....668889******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds V+ ++ + vl+   ++aYvlfY 
   Q: 358  SNGE---PVMYGLYAVLVHSGySCHAGHYYCYVKVSNGQWYQMNDSLVHLSNIKVVLN---QQAYVLFYL 421
           6654...9**************************************************...********6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPIVDKLKEV LKPGRKDSAD DGELGKLLAS SAKKVLLQKI EFEPASKSFS YQLESLKSKY 60
VLLNPKTEEA SRHKSGSEPQ ARRQGGEHVY ESCTDGVPAP QKVLFPTEQL SLKWERVYRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAATTG TCGATAAGCT GAAGGAAGTG CTGAAGCCTG GCCGCAAGGA CTCGGCGGAT 60
GATGGGGAGC TGGGGAAACT CCTGGCCTCC TCTGCCAAGA AGGTCCTACT CCAGAAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002092	Ailuropoda melanoleuca	68.97	0.00e+00	1238.00
IUUC-Atr-003102	Amborella trichopoda	40.44	5.00e-86	312.00
IUUC-Aca-005360	Anolis carolinensis	65.60	0.00e+00	895.00
IUUC-Bta-013047	Bos taurus	64.34	0.00e+00	1183.00
IUUC-Bdi-014036	Brachypodium distachyon	44.41	7.00e-85	308.00
IUUC-Cja-019203	Callithrix jacchus	69.12	0.00e+00	1238.00
IUUC-Cfa-020586	Canis familiaris	69.18	0.00e+00	1285.00
IUUC-Cpo-021804	Cavia porcellus	63.37	0.00e+00	1179.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	47.53	3.00e-52	198.00
IUUC-Csa-023137	Chlorocebus sabaeus	71.42	0.00e+00	1327.00
IUUC-Cin-025230	Ciona intestinalis	53.78	2.00e-99	355.00
IUUC-Cne-027049	Cryptococcus neoformans	33.89	1.00e-38	154.00
IUUC-Cme-027339	Cyanidioschyzon merolae	35.14	1.00e-62	233.00
IUUC-Dre-028587	Danio rerio	74.16	0.00e+00	796.00
IUUC-Dno-029149	Dasypus novemcinctus	67.26	0.00e+00	1274.00
IUUC-Dor-030836	Dipodomys ordii	67.43	0.00e+00	917.00
IUUC-Dme-032119	Drosophila melanogaster	34.17	2.00e-71	264.00
IUUC-Ete-032567	Echinops telfairi	72.92	0.00e+00	927.00
IUUC-Eca-033600	Equus caballus	69.96	0.00e+00	1295.00
IUUC-Eeu-035206	Erinaceus europaeus	51.27	6.00e-114	405.00
IUUC-Fca-036392	Felis catus	53.35	9.00e-165	573.00
IUUC-Fal-036852	Ficedula albicollis	64.80	1.00e-156	547.00
IUUC-Gmo-039033	Gadus morhua	74.08	0.00e+00	790.00
IUUC-Gga-040664	Gallus gallus	75.00	0.00e+00	739.00
IUUC-Gac-042176	Gasterosteus aculeatus	72.03	0.00e+00	790.00
IUUC-Ggo-045437	Gorilla gorilla	71.42	0.00e+00	1293.00
IUUC-Hsa-046863	Homo sapiens	71.77	0.00e+00	1305.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	66.19	0.00e+00	1202.00
IUUC-Lch-050120	Latimeria chalumnae	60.53	0.00e+00	751.00
IUUC-Lpe-051574	Leersia perrieri	42.82	2.00e-79	290.00
IUUC-Loc-052796	Lepisosteus oculatus	72.01	0.00e+00	761.00
IUUC-Mcc-055762	Macaca mulatta	71.33	0.00e+00	1307.00
IUUC-Meu-056697	Macropus eugenii	65.52	0.00e+00	1246.00
IUUC-Mtr-058537	Medicago truncatula	40.48	1.00e-86	314.00
IUUC-Mla-059049	Melampsora laricipopulina	42.51	8.00e-61	228.00
IUUC-Mga-059359	Meleagris gallopavo	73.12	8.00e-155	541.00
IUUC-Mmr-060966	Microcebus murinus	68.25	0.00e+00	1222.00
IUUC-Mdo-062733	Monodelphis domestica	63.91	0.00e+00	1200.00
IUUC-Mmu-064331	Mus musculus	65.78	0.00e+00	1225.00
IUUC-Mac-065039	Musa acuminata	40.53	7.00e-90	325.00
IUUC-Mpu-065759	Mustela putorius furo	67.49	0.00e+00	1178.00
IUUC-Mlu-067371	Myotis lucifugus	74.86	0.00e+00	1009.00
IUUC-Nle-070087	Nomascus leucogenys	70.71	0.00e+00	1278.00
IUUC-Opr-070729	Ochotona princeps	64.03	0.00e+00	965.00
IUUC-Ont-071346	Oreochromis niloticus	76.30	0.00e+00	798.00
IUUC-Oan-072931	Ornithorhynchus anatinus	65.06	0.00e+00	884.00
IUUC-Ocu-074823	Oryctolagus cuniculus	69.14	0.00e+00	902.00
IUUC-Oba-075866	Oryza barthii	45.40	6.00e-84	305.00
IUUC-Obr-076408	Oryza brachyantha	44.94	2.00e-84	306.00
IUUC-Ogl-077239	Oryza glaberrima	42.54	5.00e-85	309.00
IUUC-Ogu-078064	Oryza glumaepatula	42.54	4.00e-85	309.00
IUUC-Oin-079157	Oryza indica	42.54	5.00e-85	309.00
IUUC-Olo-080231	Oryza longistaminata	44.30	4.00e-77	283.00
IUUC-Ome-081746	Oryza meridionalis	42.90	7.00e-84	305.00
IUUC-Oni-082339	Oryza nivara	42.54	5.00e-85	309.00
IUUC-Opu-083194	Oryza punctata	42.82	6.00e-85	310.00
IUUC-Oru-085083	Oryza rufipogon	42.54	4.00e-85	309.00
IUUC-Osa-086180	Oryza sativa	42.54	5.00e-85	309.00
IUUC-Ola-087255	Oryzias latipes	72.28	0.00e+00	801.00
IUUC-Olu-087773	Ostreococcus lucimarinus	44.94	2.00e-70	258.00
IUUC-Oga-088818	Otolemur garnettii	69.85	0.00e+00	1083.00
IUUC-Oar-089410	Ovis aries	62.95	0.00e+00	1162.00
IUUC-Ptr-090680	Pan troglodytes	72.16	0.00e+00	1117.00
IUUC-Pan-092482	Papio anubis	71.06	0.00e+00	1317.00
IUUC-Ppa-095853	Physcomitrella patens	47.13	2.00e-91	330.00
IUUC-Pfo-096807	Poecilia formosa	72.68	0.00e+00	813.00
IUUC-Pab-098724	Pongo abelii	71.26	0.00e+00	1325.00
IUUC-Pop-099693	Populus trichocarpa	46.91	4.00e-83	302.00
IUUC-Pca-100117	Procavia capensis	79.77	2.00e-157	550.00
IUUC-Pva-102883	Pteropus vampyrus	56.24	0.00e+00	920.00
IUUC-Pgr-103270	Puccinia graminis	45.31	1.00e-68	254.00
IUUC-Ptt-103887	Puccinia triticina	44.34	1.00e-69	257.00
IUUC-Rno-105340	Rattus norvegicus	66.88	0.00e+00	1037.00
IUUC-Sha-107019	Sarcophilus harrisii	65.30	0.00e+00	1249.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	41.80	6.00e-77	281.00
IUUC-Spo-108119	Schizosaccharomyces pombe	44.19	5.00e-84	305.00
IUUC-Sit-110536	Setaria italica	46.52	2.00e-80	294.00
IUUC-Sly-111722	Solanum lycopersicum	40.84	2.00e-80	293.00
IUUC-Stu-112912	Solanum tuberosum	40.89	1.00e-82	301.00
IUUC-Sbi-114477	Sorghum bicolor	45.57	9.00e-86	311.00
IUUC-Sre-114924	Sporisorium reilianum	41.07	1.00e-65	244.00
IUUC-Ssc-116022	Sus scrofa	83.77	0.00e+00	872.00
IUUC-Tgu-116976	Taeniopygia guttata	70.59	5.00e-159	553.00
IUUC-Tru-118391	Takifugu rubripes	62.95	0.00e+00	806.00
IUUC-Tsy-119253	Tarsius syrichta	57.11	0.00e+00	769.00
IUUC-Tni-120064	Tetraodon nigroviridis	77.69	0.00e+00	786.00
IUUC-Tae-125259	Triticum aestivum	48.26	2.00e-88	320.00
IUUC-Tur-126014	Triticum urartu	47.39	3.00e-84	306.00
IUUC-Tbe-127377	Tupaia belangeri	56.44	0.00e+00	740.00
IUUC-Ttr-129259	Tursiops truncatus	82.69	0.00e+00	761.00
IUUC-Uma-129416	Ustilago maydis	42.90	3.00e-68	253.00
IUUC-Vpa-130568	Vicugna pacos	68.38	1.00e-44	175.00
IUUC-Xtr-132944	Xenopus tropicalis	77.96	0.00e+00	675.00
IUUC-Xma-133735	Xiphophorus maculatus	72.94	0.00e+00	816.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence