iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068852

Ensembl Protein ID

ESA43955

UniProt Accession

V5IQI3; V5IQI3_NEUCR

Genbank Protein ID

ESA43955.1

Protein Name

Ubiquitin-conjugating enzyme E2Z

Genbank Nucleotide ID

CM002236

Gene Name

NCU02688

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU02688	ESA43955	ESA43955

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-46	156.9	7	155

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}
383	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyenGkvClsilk.....eeek 91
           R++kel++l+kd+  ++ + + d  d+ + +++i+Gp++tpYe g+F++ + f++dYP ++P+v+ +t+     +f+Pn+y+nGkvClsil+     + e+
   Q: 7    RITKELSDLQKDSDLSLAVACRDV-DVRNVKAMIIGPHETPYEFGFFEFAFVFNKDYPRRSPQVQATTTndgrtRFNPNIYANGKVCLSILGtwrgeRGEQ 106
           89**********************.9******************************************99*********************66667789** PP
   S: 92   Wspalsvesvllsiqsll.aepnpesplneeaaell.kknreeykkkvr 138
           Ws+a+ +es+llsiqsl+  +p+ ++p  e+a e   +kn+++y +k+r
   Q: 107  WSAAQGLESILLSIQSLMsMNPYENEPGFEDAKEAQdQKNQKDYIQKIR 155
           ******************777**********996541677789999987 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MDQSVFRITK ELSDLQKDSD LSLAVACRDV DVRNVKAMII GPHETPYEFG FFEFAFVFNK 60
DYPRRSPQVQ ATTTNDGRTR FNPNIYANGK VCLSILGTWR GERGEQWSAA QGLESILLSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCTTACCA CTTCCTCTTC TTGCCTGAAC TCAGCTTGGT GTTGTCGTCT CGCTCGCTAC 60
TTCTCACCTC AACCACCGAC TGCTACCTGA ATGGGAAACA GAAAATACAA CTTAAGCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001098	Aegilops tauschii	39.46	1.00e-19	89.00
IUUC-Aml-001560	Ailuropoda melanoleuca	36.47	3.00e-31	127.00
IUUC-Apl-003980	Anas platyrhynchos	35.69	2.00e-30	124.00
IUUC-Aca-005372	Anolis carolinensis	35.93	7.00e-31	125.00
IUUC-Acl-008373	Aspergillus clavatus	50.93	2.00e-114	403.00
IUUC-Afl-008391	Aspergillus flavus	53.57	2.00e-101	360.00
IUUC-Afu-009108	Aspergillus fumigatus	52.20	6.00e-126	442.00
IUUC-Ani-009463	Aspergillus nidulans	53.32	1.00e-134	471.00
IUUC-Ang-009532	Aspergillus niger	50.26	2.00e-106	377.00
IUUC-Aor-010121	Aspergillus oryzae	38.52	1.00e-12	67.00
IUUC-Ate-010525	Aspergillus terreus	46.24	2.00e-110	390.00
IUUC-Ame-011940	Astyanax mexicanus	47.59	2.00e-30	125.00
IUUC-Bta-012643	Bos taurus	36.90	5.00e-33	133.00
IUUC-Bci-013596	Botrytis cinerea	67.04	6.00e-166	575.00
IUUC-Bdi-014342	Brachypodium distachyon	40.14	1.00e-20	92.80
IUUC-Cel-018661	Caenorhabditis elegans	39.53	7.00e-24	103.00
IUUC-Cja-018722	Callithrix jacchus	36.16	1.00e-31	128.00
IUUC-Cfa-020605	Canis familiaris	36.47	1.00e-31	127.00
IUUC-Cpo-021673	Cavia porcellus	36.70	5.00e-32	129.00
IUUC-Csa-024068	Chlorocebus sabaeus	36.90	5.00e-33	133.00
IUUC-Cho-024890	Choloepus hoffmanni	35.62	6.00e-16	80.50
IUUC-Cgl-026412	Colletotrichum gloeosporioides	70.69	0.00e+00	630.00
IUUC-Cne-026995	Cryptococcus neoformans	38.85	8.00e-18	84.00
IUUC-Dre-027988	Danio rerio	36.13	8.00e-31	125.00
IUUC-Dno-029140	Dasypus novemcinctus	36.30	2.00e-31	127.00
IUUC-Dor-030106	Dipodomys ordii	48.10	3.00e-29	120.00
IUUC-Dse-031321	Dothistroma septosporum	48.64	1.00e-114	405.00
IUUC-Dme-031592	Drosophila melanogaster	39.71	3.00e-19	91.70
IUUC-Ete-032587	Echinops telfairi	34.23	5.00e-16	80.50
IUUC-Eca-034348	Equus caballus	36.47	1.00e-31	127.00
IUUC-Eeu-034803	Erinaceus europaeus	38.49	6.00e-28	115.00
IUUC-Fca-036527	Felis catus	35.53	3.00e-31	127.00
IUUC-Fal-037318	Ficedula albicollis	34.81	4.00e-17	84.30
IUUC-Fox-037961	Fusarium oxysporum	70.48	9.00e-180	620.00
IUUC-Fso-038352	Fusarium solani	68.51	2.00e-172	596.00
IUUC-Gmo-038800	Gadus morhua	46.39	2.00e-29	121.00
IUUC-Ggr-040018	Gaeumannomyces graminis	74.89	0.00e+00	665.00
IUUC-Gga-041237	Gallus gallus	35.93	1.00e-30	125.00
IUUC-Gac-041848	Gasterosteus aculeatus	47.59	1.00e-30	125.00
IUUC-Ggo-045631	Gorilla gorilla	36.02	6.00e-22	95.90
IUUC-Hsa-046207	Homo sapiens	36.90	5.00e-33	133.00
IUUC-Hvu-047795	Hordeum vulgare	39.46	7.00e-21	92.80
IUUC-Itr-048609	Ictidomys tridecemlineatus	36.47	1.00e-31	127.00
IUUC-Lch-050278	Latimeria chalumnae	46.99	6.00e-31	126.00
IUUC-Lpe-050857	Leersia perrieri	40.82	2.00e-21	94.70
IUUC-Loc-052800	Lepisosteus oculatus	36.30	3.00e-17	84.70
IUUC-Lma-053044	Leptosphaeria maculans	61.25	4.00e-152	529.00
IUUC-Laf-053726	Loxodonta africana	36.19	3.00e-30	123.00
IUUC-Mcc-055267	Macaca mulatta	34.81	6.00e-17	84.00
IUUC-Meu-056221	Macropus eugenii	50.00	2.00e-23	100.00
IUUC-Mor-057074	Magnaporthe oryzae	71.52	1.00e-180	624.00
IUUC-Mpo-057495	Magnaporthe poae	74.44	0.00e+00	656.00
IUUC-Mtr-057941	Medicago truncatula	42.98	2.00e-19	88.60
IUUC-Mga-060059	Meleagris gallopavo	35.14	4.00e-31	126.00
IUUC-Mvi-060389	Microbotryum violaceum	31.49	3.00e-15	75.50
IUUC-Mmr-061455	Microcebus murinus	36.06	2.00e-31	127.00
IUUC-Mdo-062002	Monodelphis domestica	35.98	1.00e-30	124.00
IUUC-Mmu-063224	Mus musculus	36.90	5.00e-33	133.00
IUUC-Mac-064722	Musa acuminata	40.46	2.00e-18	85.10
IUUC-Mpu-066230	Mustela putorius furo	36.47	1.00e-31	127.00
IUUC-Mlu-067587	Myotis lucifugus	36.74	4.00e-31	127.00
IUUC-Nfi-068281	Neosartorya fischeri	55.74	3.00e-124	436.00
IUUC-Nle-069355	Nomascus leucogenys	48.48	7.00e-24	102.00
IUUC-Opr-070799	Ochotona princeps	34.81	5.00e-17	84.00
IUUC-Ont-071793	Oreochromis niloticus	47.59	2.00e-30	124.00
IUUC-Oan-073328	Ornithorhynchus anatinus	49.35	6.00e-30	121.00
IUUC-Ocu-073819	Oryctolagus cuniculus	36.90	4.00e-33	133.00
IUUC-Oba-075386	Oryza barthii	42.86	2.00e-22	98.20
IUUC-Obr-076484	Oryza brachyantha	42.86	3.00e-22	97.80
IUUC-Ogl-077926	Oryza glaberrima	42.86	2.00e-22	98.20
IUUC-Ogu-078653	Oryza glumaepatula	42.86	2.00e-22	98.20
IUUC-Oin-079106	Oryza indica	42.86	2.00e-22	98.20
IUUC-Olo-080468	Oryza longistaminata	42.86	1.00e-22	99.00
IUUC-Ome-081434	Oryza meridionalis	42.11	3.00e-19	88.20
IUUC-Oni-082866	Oryza nivara	42.86	2.00e-22	98.20
IUUC-Opu-083330	Oryza punctata	42.86	3.00e-22	97.80
IUUC-Oru-085215	Oryza rufipogon	42.86	3.00e-22	97.80
IUUC-Osa-085432	Oryza sativa	42.86	2.00e-22	98.20
IUUC-Ola-087432	Oryzias latipes	46.95	2.00e-29	120.00
IUUC-Oga-087941	Otolemur garnettii	36.90	5.00e-33	133.00
IUUC-Oar-089782	Ovis aries	36.47	3.00e-31	127.00
IUUC-Ptr-091361	Pan troglodytes	36.90	3.00e-33	134.00
IUUC-Pan-092426	Papio anubis	36.90	5.00e-33	133.00
IUUC-Psi-093231	Pelodiscus sinensis	39.42	6.00e-18	85.10
IUUC-Pma-094305	Petromyzon marinus	53.73	1.00e-25	107.00
IUUC-Pno-094902	Phaeosphaeria nodorum	55.90	6.00e-123	432.00
IUUC-Ppa-095592	Physcomitrella patens	39.29	6.00e-23	101.00
IUUC-Pfo-097059	Poecilia formosa	46.39	3.00e-34	137.00
IUUC-Pab-097711	Pongo abelii	50.00	1.00e-29	120.00
IUUC-Pca-100473	Procavia capensis	36.88	3.00e-31	126.00
IUUC-Ppe-101602	Prunus persica	37.75	2.00e-20	91.70
IUUC-Pva-103012	Pteropus vampyrus	36.90	5.00e-33	133.00
IUUC-Pte-104107	Pyrenophora teres	61.11	1.00e-153	534.00
IUUC-Pyt-104452	Pyrenophora triticirepentis	61.11	5.00e-154	535.00
IUUC-Rno-105444	Rattus norvegicus	36.90	5.00e-33	133.00
IUUC-Sha-107291	Sarcophilus harrisii	35.98	2.00e-30	124.00
IUUC-Smo-108915	Selaginella moellendorffii	40.15	5.00e-20	89.70
IUUC-Sit-110473	Setaria italica	43.18	1.00e-20	92.40
IUUC-Sar-113102	Sorex araneus	55.86	1.00e-22	98.60
IUUC-Sbi-114054	Sorghum bicolor	39.33	7.00e-21	92.80
IUUC-Sre-114954	Sporisorium reilianum	35.48	9.00e-18	84.00
IUUC-Ssc-115575	Sus scrofa	36.90	4.00e-33	133.00
IUUC-Tgu-117132	Taeniopygia guttata	33.96	8.00e-17	83.60
IUUC-Tru-117883	Takifugu rubripes	47.59	2.00e-30	124.00
IUUC-Tsy-118899	Tarsius syrichta	34.81	6.00e-17	84.00
IUUC-Tni-120523	Tetraodon nigroviridis	47.59	2.00e-30	125.00
IUUC-Tca-121399	Theobroma cacao	40.91	2.00e-18	85.50
IUUC-Tre-121946	Trichoderma reesei	65.41	4.00e-170	588.00
IUUC-Tvi-122513	Trichoderma virens	67.55	6.00e-178	615.00
IUUC-Tae-124135	Triticum aestivum	43.70	1.00e-19	88.60
IUUC-Tur-126255	Triticum urartu	39.46	1.00e-19	89.40
IUUC-Tme-126888	Tuber melanosporum	62.91	8.00e-155	538.00
IUUC-Ttr-128772	Tursiops truncatus	36.88	3.00e-31	126.00
IUUC-Uma-129323	Ustilago maydis	33.99	1.00e-17	83.60
IUUC-Vda-129728	Verticillium dahliae	70.00	9.00e-172	594.00
IUUC-Vpa-130763	Vicugna pacos	52.50	2.00e-22	96.70
IUUC-Xtr-132764	Xenopus tropicalis	49.10	1.00e-31	128.00
IUUC-Xma-134051	Xiphophorus maculatus	47.59	1.00e-30	125.00
IUUC-Zma-135487	Zea mays	46.15	1.00e-18	84.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence