iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lma-053218

Ensembl Protein ID

CBX90678

UniProt Accession

E4ZHA8; E4ZHA8_LEPMJ

Genbank Protein ID

CBX90678.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

FP929065

Gene Name

LEMA_P057120.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LEMA_P057120.1	CBX90678	CBX90678

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-27	93.8	185	216
UBD/Beta-Prp	1.00e-66	224.5	11	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf...sd.tllvsGsdDgtikvWDlrtg 33
           v+ +++   sd ++l++ sdD t+kvWD++t 
   Q: 185  VNFIDYypqSDkPYLLTTSDDRTVKVWDYTTK 216
           555665899999****************9986 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklv 110
           +++++ ++f+p +++++t+ ++g + +w++ t++ +++++  + +v+a +f  +++++v gs+D  ++v++++t++ v ++++h d++++++++p++++++
   Q: 11   SERVKGIDFHPVEPWILTTLYSGHVHIWSYITQSIVKTFELTDVPVRAGRFVARKNWIVAGSDDFQLRVYNYNTSEKVTSFEAHPDYIRAIAVHPTQSFVL 111
           678999*********************************************************************************************** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwd 208
           ++s+d ti++wd+++ ++  + ++gh++ v++++++p++ n ++s++lDrtv++W+l + +   tl+   t+ v+ +++ +++  ++l++ s+d+tvk+wd
   Q: 112  TASDDMTIKLWDWDKSWKCVQEFAGHQHYVMGIAINPKDpNTFASACLDRTVKIWSLGSSTPNFTLEAHETKGVNFIDYYPQSdkPYLLTTSDDRTVKVWD 212
           **************9998888***********************************************99********9998888**************** PP
   S: 209  lqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvni 291
           + t+  + tl+ght+nv+    +p+   ++sgs+Dg+i+iW + +  l ++l++  ++ ++va+ + g+n ++lg +d+ v i
   Q: 213  YTTKALIATLEGHTSNVSFAVYHPELPVIISGSEDGTIKIWHSSTYRLEQSLNYGLERAWCVAY-QKGKNGVALGFDDGAVVI 294
           ****************************************************************.888999988888887766 PP

Organism

Leptosphaeria maculans

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDVKLFAR SERVKGIDFH PVEPWILTTL YSGHVHIWSY ITQSIVKTFE LTDVPVRAGR 60
FVARKNWIVA GSDDFQLRVY NYNTSEKVTS FEAHPDYIRA IAVHPTQSFV LTASDDMTIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGTCTCG ACGTAAAGGT AGGAGACAAT ACGACTTGAA CGGCTATTTT CAGGAGGCAG 60
AAGAGTCAGT CTGACATGTT CGAACTATAG AGACAGCTAT TTGCGCGGTC GGAGCGTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	45.59	0.00e+00	741.00
IUUC-Aml-002154	Ailuropoda melanoleuca	54.66	0.00e+00	954.00
IUUC-Atr-003090	Amborella trichopoda	53.89	0.00e+00	869.00
IUUC-Apl-003976	Anas platyrhynchos	54.84	0.00e+00	948.00
IUUC-Aca-004301	Anolis carolinensis	54.96	0.00e+00	951.00
IUUC-Aly-005643	Arabidopsis lyrata	52.71	0.00e+00	862.00
IUUC-Ath-007630	Arabidopsis thaliana	52.26	0.00e+00	869.00
IUUC-Ago-007914	Ashbya gossypii	51.55	0.00e+00	830.00
IUUC-Acl-008237	Aspergillus clavatus	74.85	0.00e+00	1281.00
IUUC-Afl-008535	Aspergillus flavus	73.86	0.00e+00	1228.00
IUUC-Afu-008845	Aspergillus fumigatus	74.73	0.00e+00	1243.00
IUUC-Ani-009135	Aspergillus nidulans	74.09	0.00e+00	1223.00
IUUC-Ang-009654	Aspergillus niger	78.13	0.00e+00	1082.00
IUUC-Aor-009939	Aspergillus oryzae	74.70	0.00e+00	1299.00
IUUC-Ate-010355	Aspergillus terreus	74.97	0.00e+00	1236.00
IUUC-Ame-010922	Astyanax mexicanus	48.78	0.00e+00	813.00
IUUC-Bgr-012249	Blumeria graminis	72.96	0.00e+00	1227.00
IUUC-Bta-013579	Bos taurus	55.79	0.00e+00	877.00
IUUC-Bci-013866	Botrytis cinerea	74.88	0.00e+00	1198.00
IUUC-Bdi-015046	Brachypodium distachyon	52.44	0.00e+00	884.00
IUUC-Bol-015466	Brassica oleracea	50.67	0.00e+00	854.00
IUUC-Bra-016617	Brassica rapa	50.43	0.00e+00	850.00
IUUC-Cel-018387	Caenorhabditis elegans	49.69	0.00e+00	870.00
IUUC-Cja-019145	Callithrix jacchus	54.78	0.00e+00	956.00
IUUC-Cfa-020564	Canis familiaris	54.66	0.00e+00	954.00
IUUC-Cpo-022201	Cavia porcellus	54.66	0.00e+00	956.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	51.95	0.00e+00	841.00
IUUC-Csa-023383	Chlorocebus sabaeus	58.88	0.00e+00	728.00
IUUC-Cho-024454	Choloepus hoffmanni	51.90	0.00e+00	816.00
IUUC-Cin-025681	Ciona intestinalis	52.67	0.00e+00	887.00
IUUC-Csv-026012	Ciona savignyi	53.06	0.00e+00	881.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	69.46	0.00e+00	1103.00
IUUC-Cne-026986	Cryptococcus neoformans	57.26	0.00e+00	966.00
IUUC-Cme-027219	Cyanidioschyzon merolae	46.22	0.00e+00	765.00
IUUC-Dre-027846	Danio rerio	54.84	0.00e+00	949.00
IUUC-Dor-030462	Dipodomys ordii	53.52	0.00e+00	766.00
IUUC-Dse-031268	Dothistroma septosporum	74.97	0.00e+00	1268.00
IUUC-Dme-031791	Drosophila melanogaster	51.59	0.00e+00	878.00
IUUC-Ete-033166	Echinops telfairi	52.14	1.00e-175	608.00
IUUC-Eca-034180	Equus caballus	53.12	0.00e+00	910.00
IUUC-Eeu-035086	Erinaceus europaeus	42.35	3.00e-100	358.00
IUUC-Fca-036265	Felis catus	54.66	0.00e+00	954.00
IUUC-Fal-037202	Ficedula albicollis	54.43	0.00e+00	914.00
IUUC-Fox-037711	Fusarium oxysporum	73.26	0.00e+00	1142.00
IUUC-Fso-038268	Fusarium solani	73.18	0.00e+00	1142.00
IUUC-Gmo-039046	Gadus morhua	54.22	0.00e+00	942.00
IUUC-Ggr-039863	Gaeumannomyces graminis	75.43	0.00e+00	1190.00
IUUC-Gga-041112	Gallus gallus	54.41	0.00e+00	952.00
IUUC-Gac-041733	Gasterosteus aculeatus	54.36	0.00e+00	920.00
IUUC-Gma-044333	Glycine max	52.31	0.00e+00	885.00
IUUC-Ggo-044984	Gorilla gorilla	54.78	0.00e+00	954.00
IUUC-Hsa-046698	Homo sapiens	54.66	0.00e+00	954.00
IUUC-Hvu-047669	Hordeum vulgare	60.73	9.00e-136	474.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	54.66	0.00e+00	953.00
IUUC-Kpa-049265	Komagataella pastoris	57.65	0.00e+00	957.00
IUUC-Lch-050473	Latimeria chalumnae	54.59	0.00e+00	945.00
IUUC-Lpe-051579	Leersia perrieri	52.03	0.00e+00	869.00
IUUC-Loc-052675	Lepisosteus oculatus	54.17	0.00e+00	948.00
IUUC-Laf-053757	Loxodonta africana	54.40	0.00e+00	946.00
IUUC-Mcc-054859	Macaca mulatta	54.78	0.00e+00	955.00
IUUC-Meu-056174	Macropus eugenii	44.51	5.00e-86	310.00
IUUC-Mor-057264	Magnaporthe oryzae	73.84	0.00e+00	1161.00
IUUC-Mpo-057538	Magnaporthe poae	75.06	0.00e+00	1206.00
IUUC-Mtr-058310	Medicago truncatula	51.95	0.00e+00	881.00
IUUC-Mla-058937	Melampsora laricipopulina	55.01	0.00e+00	927.00
IUUC-Mga-059875	Meleagris gallopavo	54.16	0.00e+00	946.00
IUUC-Mvi-060240	Microbotryum violaceum	56.90	0.00e+00	977.00
IUUC-Mmr-061261	Microcebus murinus	54.66	0.00e+00	954.00
IUUC-Mdo-062076	Monodelphis domestica	54.49	0.00e+00	957.00
IUUC-Mmu-063324	Mus musculus	54.53	0.00e+00	953.00
IUUC-Mac-064636	Musa acuminata	52.81	0.00e+00	860.00
IUUC-Mpu-065961	Mustela putorius furo	54.66	0.00e+00	953.00
IUUC-Mlu-067059	Myotis lucifugus	54.41	0.00e+00	927.00
IUUC-Nfi-068277	Neosartorya fischeri	75.12	0.00e+00	1237.00
IUUC-Ncr-068659	Neurospora crassa	72.85	0.00e+00	1228.00
IUUC-Nle-069034	Nomascus leucogenys	54.78	0.00e+00	954.00
IUUC-Opr-070334	Ochotona princeps	56.10	0.00e+00	895.00
IUUC-Ont-071563	Oreochromis niloticus	54.59	0.00e+00	944.00
IUUC-Oan-073416	Ornithorhynchus anatinus	54.69	0.00e+00	918.00
IUUC-Ocu-074522	Oryctolagus cuniculus	54.53	0.00e+00	950.00
IUUC-Oba-075760	Oryza barthii	51.53	0.00e+00	855.00
IUUC-Obr-076163	Oryza brachyantha	51.96	0.00e+00	871.00
IUUC-Ogl-077450	Oryza glaberrima	52.14	0.00e+00	877.00
IUUC-Ogu-078994	Oryza glumaepatula	51.53	0.00e+00	853.00
IUUC-Oin-079856	Oryza indica	52.04	0.00e+00	868.00
IUUC-Olo-080731	Oryza longistaminata	51.90	0.00e+00	847.00
IUUC-Ome-081554	Oryza meridionalis	48.90	0.00e+00	797.00
IUUC-Oni-082324	Oryza nivara	51.53	0.00e+00	855.00
IUUC-Opu-083400	Oryza punctata	50.12	0.00e+00	848.00
IUUC-Oru-084829	Oryza rufipogon	51.53	0.00e+00	855.00
IUUC-Osa-086026	Oryza sativa	52.26	0.00e+00	879.00
IUUC-Ola-087245	Oryzias latipes	54.00	0.00e+00	948.00
IUUC-Olu-087655	Ostreococcus lucimarinus	51.29	0.00e+00	861.00
IUUC-Oga-088163	Otolemur garnettii	52.57	0.00e+00	905.00
IUUC-Oar-089842	Ovis aries	54.53	0.00e+00	953.00
IUUC-Ptr-090501	Pan troglodytes	54.78	0.00e+00	954.00
IUUC-Pan-092011	Papio anubis	54.78	0.00e+00	955.00
IUUC-Psi-093308	Pelodiscus sinensis	54.72	0.00e+00	951.00
IUUC-Pma-094695	Petromyzon marinus	53.61	0.00e+00	880.00
IUUC-Pno-094785	Phaeosphaeria nodorum	95.12	6.00e-166	575.00
IUUC-Ppa-095911	Physcomitrella patens	52.94	0.00e+00	885.00
IUUC-Pfo-096587	Poecilia formosa	55.09	0.00e+00	951.00
IUUC-Pab-097926	Pongo abelii	53.48	0.00e+00	889.00
IUUC-Pop-099634	Populus trichocarpa	52.20	0.00e+00	883.00
IUUC-Pca-100965	Procavia capensis	53.68	0.00e+00	920.00
IUUC-Ppe-101470	Prunus persica	52.20	0.00e+00	884.00
IUUC-Pva-102451	Pteropus vampyrus	52.77	0.00e+00	756.00
IUUC-Pgr-103590	Puccinia graminis	55.07	0.00e+00	950.00
IUUC-Ptt-103868	Puccinia triticina	54.83	0.00e+00	947.00
IUUC-Pte-104274	Pyrenophora teres	93.39	0.00e+00	1528.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	89.58	0.00e+00	1474.00
IUUC-Rno-105979	Rattus norvegicus	47.35	0.00e+00	720.00
IUUC-Sce-106269	Saccharomyces cerevisiae	51.60	0.00e+00	853.00
IUUC-Sha-106905	Sarcophilus harrisii	54.49	0.00e+00	956.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	51.71	0.00e+00	848.00
IUUC-Spo-108299	Schizosaccharomyces pombe	51.77	0.00e+00	875.00
IUUC-Smo-108695	Selaginella moellendorffii	50.98	0.00e+00	868.00
IUUC-Sit-110239	Setaria italica	52.75	0.00e+00	884.00
IUUC-Sly-111775	Solanum lycopersicum	52.04	0.00e+00	870.00
IUUC-Stu-112906	Solanum tuberosum	51.94	0.00e+00	787.00
IUUC-Sar-113472	Sorex araneus	52.57	0.00e+00	699.00
IUUC-Sbi-114052	Sorghum bicolor	52.70	0.00e+00	889.00
IUUC-Sre-115040	Sporisorium reilianum	55.73	0.00e+00	951.00
IUUC-Ssc-115593	Sus scrofa	54.66	0.00e+00	954.00
IUUC-Tgu-117239	Taeniopygia guttata	54.71	0.00e+00	949.00
IUUC-Tru-118025	Takifugu rubripes	54.40	0.00e+00	941.00
IUUC-Tsy-118824	Tarsius syrichta	51.67	0.00e+00	690.00
IUUC-Tni-120142	Tetraodon nigroviridis	53.99	0.00e+00	937.00
IUUC-Tca-121613	Theobroma cacao	52.32	0.00e+00	882.00
IUUC-Tre-122072	Trichoderma reesei	72.35	0.00e+00	1212.00
IUUC-Tvi-122546	Trichoderma virens	73.17	0.00e+00	1217.00
IUUC-Tae-125395	Triticum aestivum	52.51	0.00e+00	877.00
IUUC-Tur-126283	Triticum urartu	46.01	0.00e+00	732.00
IUUC-Tme-127041	Tuber melanosporum	71.27	0.00e+00	1215.00
IUUC-Tbe-127770	Tupaia belangeri	54.87	0.00e+00	786.00
IUUC-Ttr-129294	Tursiops truncatus	54.78	0.00e+00	953.00
IUUC-Uma-129351	Ustilago maydis	54.98	0.00e+00	942.00
IUUC-Vda-129716	Verticillium dahliae	74.54	0.00e+00	1248.00
IUUC-Vpa-130037	Vicugna pacos	43.97	8.00e-109	386.00
IUUC-Vvi-131689	Vitis vinifera	52.57	0.00e+00	878.00
IUUC-Xtr-132633	Xenopus tropicalis	54.71	0.00e+00	948.00
IUUC-Xma-133347	Xiphophorus maculatus	54.96	0.00e+00	950.00
IUUC-Yli-134455	Yarrowia lipolytica	56.01	0.00e+00	921.00
IUUC-Zma-135867	Zea mays	52.45	0.00e+00	886.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence