iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023429

Ensembl Protein ID

ENSCSAP00000013659.1

UniProt Accession

A0A0D9RYH0; A0A0D9RYH0_CHLSB

Genbank Protein ID

ENSCSAP00000013659

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01129185

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000017633.1	ENSCSAT00000015728.1	ENSCSAP00000013659.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.40e-66	222.8	105	480
ULD/UDP/UBQ/UBQ_Other	1.20e-09	37.9	5	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+++l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKDALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekge 191
           7******************************.****************************.99999******************999*9 PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+  ++ +++e+        s++a+  +++k+ksli++ F++++++++kc e +++ +++ + ++l
   Q: 192  qgQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETD-------SSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQL 273
           999*********************664444444443.......33478899**************************999999888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 274  QLSCFINQEV--KYLFTGLKLRLQEEITK-----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDM 355
           8888877754..58999999999999998.....58899999999******************************************** PP
   S: 262  spfcts........................peekqke...........................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                         p     +                           +  Y+L av+ H+G s+ssGHYv++
   Q: 356  YELCTPelqekmmsfrskfkdledkkvnqqP-----NtsdkksspqkevkyepfsfaddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 439
           ******7777777777777777666666661.....0444455666667777777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 440  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 480
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           +vtvk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd ++++ ++k+g+t++++ +
   Q: 5    SVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDD-DWGNIKIKNGMTLLMMGS 74
           69********99*************************************999.9**************965 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MPLYSVTVKW GKEKFEGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKDDDWGN 60
IKIKNGMTLL MMGSADALPE EPSAKTVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGTCCCTC CCTCGCTCCC TCCTTGCTTC CCGCCACCCC TCCACCGCCT TCCCCCTCCT 60
CCCTCCTCTC GCCACCTCCA GGCCCCGCCC CGGCCCTGCC GCCCTATCTC CTCCCTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

csab:103222671

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.96	2.00e-38	153.00
IUUC-Aml-002053	Ailuropoda melanoleuca	98.78	0.00e+00	932.00
IUUC-Atr-002725	Amborella trichopoda	42.03	6.00e-103	367.00
IUUC-Apl-004031	Anas platyrhynchos	91.04	0.00e+00	890.00
IUUC-Aca-004361	Anolis carolinensis	89.07	0.00e+00	909.00
IUUC-Aly-006078	Arabidopsis lyrata	42.20	2.00e-112	399.00
IUUC-Ath-007623	Arabidopsis thaliana	42.18	9.00e-113	400.00
IUUC-Ago-007796	Ashbya gossypii	32.22	2.00e-58	219.00
IUUC-Acl-008258	Aspergillus clavatus	36.27	2.00e-64	240.00
IUUC-Afl-008732	Aspergillus flavus	33.85	2.00e-77	283.00
IUUC-Afu-008755	Aspergillus fumigatus	34.83	9.00e-80	291.00
IUUC-Ani-009148	Aspergillus nidulans	37.90	4.00e-70	258.00
IUUC-Ang-009878	Aspergillus niger	37.32	4.00e-65	242.00
IUUC-Aor-010239	Aspergillus oryzae	33.85	2.00e-77	283.00
IUUC-Ate-010243	Aspergillus terreus	33.74	1.00e-70	260.00
IUUC-Ame-011327	Astyanax mexicanus	50.91	8.00e-127	447.00
IUUC-Bgr-012231	Blumeria graminis	34.15	4.00e-79	288.00
IUUC-Bta-012553	Bos taurus	97.36	0.00e+00	946.00
IUUC-Bci-013606	Botrytis cinerea	39.95	1.00e-69	257.00
IUUC-Bdi-014567	Brachypodium distachyon	42.91	2.00e-112	399.00
IUUC-Bol-016127	Brassica oleracea	42.60	2.00e-114	405.00
IUUC-Bra-017501	Brassica rapa	42.40	2.00e-113	402.00
IUUC-Cel-018140	Caenorhabditis elegans	41.35	6.00e-100	357.00
IUUC-Cja-019516	Callithrix jacchus	98.79	0.00e+00	963.00
IUUC-Cfa-020808	Canis familiaris	98.99	0.00e+00	958.00
IUUC-Cpo-021688	Cavia porcellus	96.75	0.00e+00	937.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.78	8.00e-83	300.00
IUUC-Cho-024347	Choloepus hoffmanni	97.57	0.00e+00	953.00
IUUC-Cin-025198	Ciona intestinalis	54.38	3.00e-151	528.00
IUUC-Csv-026007	Ciona savignyi	53.01	3.00e-153	535.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	38.44	2.00e-63	236.00
IUUC-Cne-026963	Cryptococcus neoformans	34.68	1.00e-76	280.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.62	6.00e-60	224.00
IUUC-Dre-027647	Danio rerio	82.24	0.00e+00	830.00
IUUC-Dno-029967	Dasypus novemcinctus	97.97	0.00e+00	934.00
IUUC-Dor-030886	Dipodomys ordii	92.26	0.00e+00	762.00
IUUC-Dse-031466	Dothistroma septosporum	35.03	1.00e-56	214.00
IUUC-Dme-032079	Drosophila melanogaster	55.35	5.00e-159	553.00
IUUC-Ete-032351	Echinops telfairi	86.00	0.00e+00	857.00
IUUC-Eca-033461	Equus caballus	97.97	0.00e+00	991.00
IUUC-Eeu-035220	Erinaceus europaeus	74.13	0.00e+00	686.00
IUUC-Fca-036210	Felis catus	99.19	0.00e+00	960.00
IUUC-Fal-037528	Ficedula albicollis	90.45	0.00e+00	873.00
IUUC-Fox-037805	Fusarium oxysporum	39.90	2.00e-70	259.00
IUUC-Fso-038177	Fusarium solani	37.56	3.00e-67	249.00
IUUC-Gmo-038953	Gadus morhua	78.21	0.00e+00	767.00
IUUC-Ggr-039972	Gaeumannomyces graminis	34.12	1.00e-73	270.00
IUUC-Gga-040462	Gallus gallus	90.06	0.00e+00	883.00
IUUC-Gac-041312	Gasterosteus aculeatus	81.72	0.00e+00	803.00
IUUC-Gma-043255	Glycine max	42.43	5.00e-109	387.00
IUUC-Ggo-045458	Gorilla gorilla	82.63	0.00e+00	788.00
IUUC-Hsa-045706	Homo sapiens	99.80	0.00e+00	946.00
IUUC-Hvu-047821	Hordeum vulgare	46.76	1.00e-57	216.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	97.97	0.00e+00	959.00
IUUC-Lch-050464	Latimeria chalumnae	82.45	0.00e+00	821.00
IUUC-Lpe-051419	Leersia perrieri	42.71	2.00e-108	385.00
IUUC-Loc-052732	Lepisosteus oculatus	80.65	0.00e+00	839.00
IUUC-Lma-053177	Leptosphaeria maculans	40.67	3.00e-70	259.00
IUUC-Laf-053822	Loxodonta africana	97.77	0.00e+00	948.00
IUUC-Mcc-055893	Macaca mulatta	99.80	0.00e+00	946.00
IUUC-Meu-056307	Macropus eugenii	82.38	0.00e+00	792.00
IUUC-Mor-057171	Magnaporthe oryzae	38.42	1.00e-67	250.00
IUUC-Mpo-057415	Magnaporthe poae	38.83	2.00e-69	256.00
IUUC-Mtr-057901	Medicago truncatula	43.23	9.00e-112	397.00
IUUC-Mla-058897	Melampsora laricipopulina	39.63	1.00e-75	277.00
IUUC-Mga-060016	Meleagris gallopavo	90.63	0.00e+00	887.00
IUUC-Mvi-060562	Microbotryum violaceum	38.77	2.00e-67	249.00
IUUC-Mmr-060624	Microcebus murinus	97.77	0.00e+00	995.00
IUUC-Mdo-061809	Monodelphis domestica	93.12	0.00e+00	899.00
IUUC-Mmu-063869	Mus musculus	96.55	0.00e+00	937.00
IUUC-Mac-064876	Musa acuminata	39.68	5.00e-97	348.00
IUUC-Mpu-066480	Mustela putorius furo	98.58	0.00e+00	955.00
IUUC-Mlu-067866	Myotis lucifugus	97.36	0.00e+00	955.00
IUUC-Nfi-068393	Neosartorya fischeri	36.38	5.00e-65	241.00
IUUC-Ncr-068815	Neurospora crassa	35.84	6.00e-82	298.00
IUUC-Nle-070121	Nomascus leucogenys	100.00	4.00e-141	493.00
IUUC-Opr-070712	Ochotona princeps	77.10	7.00e-173	600.00
IUUC-Ont-071544	Oreochromis niloticus	81.87	0.00e+00	770.00
IUUC-Oan-073635	Ornithorhynchus anatinus	91.33	0.00e+00	742.00
IUUC-Ocu-074926	Oryctolagus cuniculus	96.96	0.00e+00	929.00
IUUC-Oba-075633	Oryza barthii	42.18	1.00e-108	386.00
IUUC-Obr-076423	Oryza brachyantha	42.86	1.00e-110	393.00
IUUC-Ogl-077913	Oryza glaberrima	42.02	3.00e-111	395.00
IUUC-Ogu-078435	Oryza glumaepatula	42.18	1.00e-108	386.00
IUUC-Oin-080072	Oryza indica	42.15	9.00e-109	387.00
IUUC-Olo-080535	Oryza longistaminata	39.00	3.00e-93	335.00
IUUC-Ome-081309	Oryza meridionalis	42.18	1.00e-108	386.00
IUUC-Oni-083113	Oryza nivara	42.18	1.00e-108	386.00
IUUC-Opu-083168	Oryza punctata	41.24	5.00e-103	367.00
IUUC-Oru-084253	Oryza rufipogon	42.18	1.00e-108	386.00
IUUC-Osa-085554	Oryza sativa	42.02	3.00e-111	395.00
IUUC-Ola-086998	Oryzias latipes	81.14	0.00e+00	794.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.09	4.00e-71	261.00
IUUC-Oga-088571	Otolemur garnettii	97.77	0.00e+00	946.00
IUUC-Oar-089526	Ovis aries	97.15	0.00e+00	939.00
IUUC-Ptr-091433	Pan troglodytes	99.80	0.00e+00	946.00
IUUC-Pan-091966	Papio anubis	100.00	0.00e+00	947.00
IUUC-Psi-093458	Pelodiscus sinensis	89.01	0.00e+00	849.00
IUUC-Pma-094343	Petromyzon marinus	68.86	4.00e-121	427.00
IUUC-Pno-095109	Phaeosphaeria nodorum	39.65	2.00e-65	243.00
IUUC-Ppa-095756	Physcomitrella patens	43.70	5.00e-111	394.00
IUUC-Pfo-096514	Poecilia formosa	82.28	0.00e+00	785.00
IUUC-Pab-098477	Pongo abelii	87.23	0.00e+00	747.00
IUUC-Pop-099221	Populus trichocarpa	41.16	2.00e-103	369.00
IUUC-Pca-100791	Procavia capensis	81.31	7.00e-179	619.00
IUUC-Ppe-101812	Prunus persica	41.77	1.00e-107	383.00
IUUC-Pva-102462	Pteropus vampyrus	92.99	0.00e+00	765.00
IUUC-Pgr-103623	Puccinia graminis	40.69	6.00e-75	275.00
IUUC-Ptt-103767	Puccinia triticina	39.40	3.00e-68	252.00
IUUC-Pte-104109	Pyrenophora teres	38.69	3.00e-69	256.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.72	1.00e-69	257.00
IUUC-Rno-105351	Rattus norvegicus	96.55	0.00e+00	902.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.21	3.00e-62	232.00
IUUC-Sha-107491	Sarcophilus harrisii	92.90	0.00e+00	910.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	33.73	6.00e-78	284.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.63	1.00e-80	293.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	34.74	4.00e-84	305.00
IUUC-Smo-108805	Selaginella moellendorffii	43.27	6.00e-110	390.00
IUUC-Sit-110361	Setaria italica	42.34	2.00e-113	402.00
IUUC-Sly-110965	Solanum lycopersicum	40.35	2.00e-108	386.00
IUUC-Sar-113355	Sorex araneus	84.35	0.00e+00	659.00
IUUC-Sbi-114778	Sorghum bicolor	43.03	2.00e-112	399.00
IUUC-Sre-115011	Sporisorium reilianum	36.06	1.00e-61	230.00
IUUC-Ssc-116273	Sus scrofa	97.56	0.00e+00	934.00
IUUC-Tgu-117063	Taeniopygia guttata	89.82	0.00e+00	869.00
IUUC-Tru-118381	Takifugu rubripes	78.86	0.00e+00	790.00
IUUC-Tsy-119076	Tarsius syrichta	82.14	3.00e-119	421.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.02	0.00e+00	782.00
IUUC-Tca-121246	Theobroma cacao	41.49	1.00e-109	389.00
IUUC-Tre-121969	Trichoderma reesei	34.49	3.00e-75	276.00
IUUC-Tvi-122543	Trichoderma virens	34.87	3.00e-77	282.00
IUUC-Tae-125484	Triticum aestivum	41.88	3.00e-109	388.00
IUUC-Tur-126128	Triticum urartu	41.87	2.00e-39	156.00
IUUC-Tbe-128030	Tupaia belangeri	90.97	0.00e+00	851.00
IUUC-Ttr-128701	Tursiops truncatus	96.69	0.00e+00	766.00
IUUC-Uma-129657	Ustilago maydis	36.80	8.00e-65	241.00
IUUC-Vda-129723	Verticillium dahliae	32.31	3.00e-71	262.00
IUUC-Vpa-130284	Vicugna pacos	70.64	0.00e+00	632.00
IUUC-Vvi-131037	Vitis vinifera	42.55	2.00e-108	386.00
IUUC-Xtr-132235	Xenopus tropicalis	85.86	0.00e+00	875.00
IUUC-Xma-133840	Xiphophorus maculatus	82.28	0.00e+00	810.00
IUUC-Yli-134453	Yarrowia lipolytica	36.78	3.00e-82	298.00
IUUC-Zma-135669	Zea mays	36.27	4.00e-94	338.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence